MC1816A1 - Derives d'isoquinoleine - Google Patents

Derives d'isoquinoleine

Info

Publication number
MC1816A1
MC1816A1 MC871887A MC1887A MC1816A1 MC 1816 A1 MC1816 A1 MC 1816A1 MC 871887 A MC871887 A MC 871887A MC 1887 A MC1887 A MC 1887A MC 1816 A1 MC1816 A1 MC 1816A1
Authority
MC
Monaco
Prior art keywords
dimethyl
group
formula
trans
alkyl
Prior art date
Application number
MC871887A
Other languages
English (en)
French (fr)
Inventor
Berger Leo
Olson Gary-Lee
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1816A1 publication Critical patent/MC1816A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MC871887A 1986-05-23 1987-05-21 Derives d'isoquinoleine MC1816A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/866,532 US4732902A (en) 1986-05-23 1986-05-23 Pyrroloisoquinolinyl-dimethyloxoalkyl alkonoates and their use as antipsychotic agents

Publications (1)

Publication Number Publication Date
MC1816A1 true MC1816A1 (fr) 1988-03-18

Family

ID=25347803

Family Applications (1)

Application Number Title Priority Date Filing Date
MC871887A MC1816A1 (fr) 1986-05-23 1987-05-21 Derives d'isoquinoleine

Country Status (14)

Country Link
US (1) US4732902A (da)
EP (1) EP0246529A3 (da)
JP (1) JPS62283971A (da)
KR (1) KR870011138A (da)
AU (1) AU7331587A (da)
DK (1) DK255687A (da)
FI (1) FI872233A7 (da)
HU (1) HU197744B (da)
IL (1) IL82594A0 (da)
MC (1) MC1816A1 (da)
NO (1) NO872157L (da)
NZ (1) NZ220383A (da)
PT (1) PT84937B (da)
ZA (1) ZA873637B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851417A (en) * 1988-05-26 1989-07-25 Rensselaer Polytechnic Institute 9-substituted 6H-pyrido[4,3-b]carbazoles
US8354444B2 (en) 2008-09-18 2013-01-15 Hoffmann-La Roche Inc. Substituted pyrrolidine-2-carboxamides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260762A (en) * 1979-09-10 1981-04-07 Hoffmann-La Roche Inc. Octahydro-1H-pyrrolo[2,3-g]isoquinolines
CA1132553A (en) * 1978-10-13 1982-09-28 Gary L. Olson Isoquinoline derivatives
MC1377A1 (fr) * 1980-02-28 1982-01-19 Hoffmann La Roche Derives d'isoquinoleine
US4334070A (en) * 1980-12-15 1982-06-08 Hoffmann-La Roche Inc. Cycloalka[4,5]pyrrolo[2,3-g]isoquinolines

Also Published As

Publication number Publication date
EP0246529A2 (en) 1987-11-25
US4732902A (en) 1988-03-22
HUT43601A (en) 1987-11-30
IL82594A0 (en) 1987-11-30
NZ220383A (en) 1990-07-26
KR870011138A (ko) 1987-12-21
AU7331587A (en) 1987-11-26
PT84937B (en) 1989-07-21
DK255687D0 (da) 1987-05-20
FI872233A0 (fi) 1987-05-21
DK255687A (da) 1987-11-24
NO872157L (no) 1987-11-24
PT84937A (en) 1987-06-01
FI872233A7 (fi) 1987-11-24
ZA873637B (en) 1988-01-27
NO872157D0 (no) 1987-05-22
JPS62283971A (ja) 1987-12-09
HU197744B (en) 1989-05-29
EP0246529A3 (en) 1989-04-19

Similar Documents

Publication Publication Date Title
EP0018342B1 (fr) Nouveaux dérivés du glycerol, leurs procédés de préparation ainsi que les compositions pharmaceutiques les contenant
EP0302788A1 (fr) Dérivés de [(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 9H-pyrido[3,4-b]indole, leur préparation et leur application en thérapeutique
CH645642A5 (fr) Derives de d-6-n-propylergolines, leur procede de preparation et compositions pharmaceutiques en contenant.
EP0110755B1 (fr) Dérivés de la pipéridinedione protecteurs du myocarde présentant une activité antiarythmique, leur procédé de préparation et les médicaments qui contiennent lesdits dérivés
EP0343050B1 (fr) Dérivés de phényl-6 pipérazinyl-alkyl-3 1H,3H-pyrimidinedione-2,4, leur préparation et leur application en thérapeutique
EP0337858B1 (fr) Procédé stéréospécifique pour la préparation des enantiomères de la furo[3,4-c]pyridine, composés ainsi obtenus et compositions thérapeutiques à base de ces composés
EP0351255B1 (fr) Dérivés de [(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
FR2621587A1 (fr) Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant
MC1357A1 (fr) Derives de 2,3-indoledione
MC1816A1 (fr) Derives d'isoquinoleine
EP0099303A2 (fr) Nouvelles benzothiopyranopyridinones et leurs sels, leur préparation, leur application comme médicaments et les compositions les renfermant
FR2510575A1 (fr) Nouveaux composes bicycliques, leur procede de preparation et composition pharmaceutique les renfermant
CH626881A5 (en) Process for the preparation of new octahydrobenzo[c]quinolines
EP0302787B1 (fr) Dérivés de (pipéridinyl-4)méthyl-2 benzofuro[2,3-c]pyridines, leur préparation et leur application en thérapeutique
FR2565586A1 (fr) Derives de la naphtoxazine, leur preparation, leur application comme medicaments et compositions pharmaceutiques les contenant
CA1060020A (fr) Procede de preparation de nouveaux derives de la dibenzo/b,c/ thiepine et leurs sels
EP0351283A1 (fr) Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique
JPS6323189B2 (da)
EP0007828A1 (fr) Procédé de préparation d'esters d'alcoyle de l'acide dl-cis chrysanthémique
EP0026168B1 (fr) Nouveaux dérivés de décahydroquinoléinol, leur procédé de préparation ainsi que leurs applications en thérapeutique
CH642655A5 (fr) Derives bromes de la vincamine, leur procede d'obtention et leur application en tant que medicaments.
EP0337885A1 (fr) Nouveaux dérivés triéniques de structure chroménique, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
FR2690917A1 (fr) Aminoesters, leur procédé de préparation et leur application en thérapeutique.
EP0324111B1 (fr) Procédé pour la préparation d'aldéhydes cycloaliphatiques
BE874322R (fr) Nouveaux composes heterocycliques, leur preparation et leur application comme medicaments

Legal Events

Date Code Title Description
YP Annual fee paid