MEP11809A - Jedinjenje indola - Google Patents

Jedinjenje indola

Info

Publication number
MEP11809A
MEP11809A MEP-118/09A MEP11809A MEP11809A ME P11809 A MEP11809 A ME P11809A ME P11809 A MEP11809 A ME P11809A ME P11809 A MEP11809 A ME P11809A
Authority
ME
Montenegro
Prior art keywords
indole compound
present
glucokinase activator
prodrug
prophylaxis
Prior art date
Application number
MEP-118/09A
Other languages
English (en)
Inventor
Tsuneo Yasuma
Osamu Ujikawa
Masahiro Itoh
Kazuko Aoki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39010108&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MEP11809(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of ME00681B publication Critical patent/ME00681B/me
Publication of MEP11809A publication Critical patent/MEP11809A/bs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Svrha ovog pronalaska je da obezbijedi akti vator glukokinaze koristan kao farmaceutsko sredstvo kao što je sredstvo za profi laksu ili tretman dijabeti sa, gojaznosti i sl. Ovaj pronalazak obezbjeđuje akti vator glukokinaze koji sadrži jedinjenje predstavljeno formulom (I): gdje R1 je atom vodonika ili atom halogene; R2 je grupa predstavljena sa Gdje je svaki simbol defi nisan u specifi kacij, ili njegovu so ili njegov prolek.
MEP-118/09A 2006-10-19 2007-10-18 Jedinjenje indola MEP11809A (bs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006285551 2006-10-19
PCT/JP2007/070772 WO2008050821A1 (en) 2006-10-19 2007-10-18 Indole compound

Publications (2)

Publication Number Publication Date
ME00681B ME00681B (me) 2011-12-20
MEP11809A true MEP11809A (bs) 2011-12-20

Family

ID=39010108

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-118/09A MEP11809A (bs) 2006-10-19 2007-10-18 Jedinjenje indola

Country Status (26)

Country Link
US (4) US7652133B2 (bs)
EP (2) EP2508524A3 (bs)
JP (1) JP5260507B2 (bs)
KR (1) KR101444486B1 (bs)
CN (1) CN101573357B (bs)
AU (1) AU2007310064B2 (bs)
BR (1) BRPI0717722A2 (bs)
CA (1) CA2666973C (bs)
CL (1) CL2008001017A1 (bs)
CR (1) CR10748A (bs)
EC (1) ECSP099330A (bs)
GE (1) GEP20115241B (bs)
IL (1) IL198154A (bs)
MA (1) MA30890B1 (bs)
ME (1) MEP11809A (bs)
MX (1) MX2009003972A (bs)
MY (1) MY158052A (bs)
NO (1) NO20091948L (bs)
NZ (1) NZ576570A (bs)
PE (1) PE20090884A1 (bs)
RU (1) RU2454415C9 (bs)
TN (1) TN2009000129A1 (bs)
TW (1) TWI460176B (bs)
UA (1) UA97257C2 (bs)
WO (1) WO2008050821A1 (bs)
ZA (1) ZA200902585B (bs)

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Also Published As

Publication number Publication date
BRPI0717722A2 (pt) 2013-10-29
CN101573357B (zh) 2013-01-23
GEP20115241B (en) 2011-06-10
US7718798B2 (en) 2010-05-18
RU2454415C2 (ru) 2012-06-27
UA97257C2 (en) 2012-01-25
US20100137610A1 (en) 2010-06-03
WO2008050821A1 (en) 2008-05-02
IL198154A (en) 2014-08-31
ME00681B (me) 2011-12-20
US20080096877A1 (en) 2008-04-24
MX2009003972A (es) 2009-04-27
US7652133B2 (en) 2010-01-26
EP2508524A2 (en) 2012-10-10
ECSP099330A (es) 2009-06-30
NZ576570A (en) 2010-11-26
JP5260507B2 (ja) 2013-08-14
JP2010506825A (ja) 2010-03-04
PE20090884A1 (es) 2009-08-05
CR10748A (es) 2009-05-20
US8410087B2 (en) 2013-04-02
AU2007310064A2 (en) 2009-06-04
TN2009000129A1 (en) 2010-10-18
EP2074119A1 (en) 2009-07-01
AU2007310064B2 (en) 2013-03-28
US7777047B2 (en) 2010-08-17
EP2508524A3 (en) 2012-10-24
RU2009118602A (ru) 2010-11-27
MA30890B1 (fr) 2009-11-02
RU2454415C9 (ru) 2013-02-27
CA2666973C (en) 2015-03-31
MY158052A (en) 2016-08-30
ZA200902585B (en) 2010-09-29
CL2008001017A1 (es) 2009-04-24
US20100144702A1 (en) 2010-06-10
KR20090068292A (ko) 2009-06-25
KR101444486B1 (ko) 2014-09-24
CN101573357A (zh) 2009-11-04
CA2666973A1 (en) 2008-05-02
TW200825071A (en) 2008-06-16
TWI460176B (zh) 2014-11-11
US20090286975A1 (en) 2009-11-19
NO20091948L (no) 2009-07-13
IL198154A0 (en) 2009-12-24
AU2007310064A1 (en) 2008-05-02

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