MEP16408A - Combination of a taxane and a cyclin-dependent kinase inhibitor - Google Patents

Combination of a taxane and a cyclin-dependent kinase inhibitor

Info

Publication number: MEP16408A
Authority: ME; Montenegro
Prior art keywords: cyclin; dependent kinase; taxane; combination; kinase inhibitor
Prior art date: 2001-03-23

Application number

MEP-164/08A

Other languages

Bosnian (bs)

English (en)

Croatian (hr)

Inventor

Marie-Christi Ne Bissery

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-23

Filing date

2002-03-22

Publication date

2010-10-10

2002-03-22 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2010-10-10 Publication of MEP16408A publication Critical patent/MEP16408A/xx

Links

229940126074 CDK kinase inhibitor Drugs 0.000 title 1
102100034770 Cyclin-dependent kinase inhibitor 3 Human genes 0.000 title 1
101000945639 Homo sapiens Cyclin-dependent kinase inhibitor 3 Proteins 0.000 title 1
229940123237 Taxane Drugs 0.000 title 1
239000002875 cyclin dependent kinase inhibitor Substances 0.000 title 1
229940043378 cyclin-dependent kinase inhibitor Drugs 0.000 title 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
102000003903 Cyclin-dependent kinases Human genes 0.000 abstract 2
108090000266 Cyclin-dependent kinases Proteins 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229930184616 taxin Natural products 0.000 abstract 1
KOTXAHKUCAQPQA-AAUVPWARSA-N taxine Chemical compound C1([C@@H]([C@@H](O)C(=O)O[C@@H]2C=3/C[C@@](C([C@H](O)C4=C(C)[C@@H](OC(C)=O)CC(C4(C)C)[C@@H](OC(C)=O)\C=3)=O)(C)[C@@H](O)C2)N(C)C)=CC=CC=C1 KOTXAHKUCAQPQA-AAUVPWARSA-N 0.000 abstract 1
RCINICONZNJXQF-XAZOAEDWSA-N taxol® Chemical compound O([C@@H]1[C@@]2(CC(C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3(C21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-XAZOAEDWSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

MEP-164/08A 2001-03-23 2002-03-22 Combination of a taxane and a cyclin-dependent kinase inhibitor MEP16408A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US27794801P	2001-03-23	2001-03-23
US30269201P	2001-07-05	2001-07-05
US33491601P	2001-12-04	2001-12-04
PCT/EP2002/004083 WO2002076484A2 (en)	2001-03-23	2002-03-22	Combination of a taxane and a cyclin-dependent kinase inhibitor

Publications (1)

Publication Number	Publication Date
MEP16408A true MEP16408A (en)	2010-10-10

Family

ID=27402954

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MEP-164/08A MEP16408A (en)	2001-03-23	2002-03-22	Combination of a taxane and a cyclin-dependent kinase inhibitor

Country Status (33)

Country	Link
US (2)	US20020182204A1 (de)
EP (1)	EP1372652B1 (de)
JP (1)	JP2004521140A (de)
KR (1)	KR100879712B1 (de)
CN (1)	CN1498107A (de)
AR (1)	AR034222A1 (de)
AT (1)	ATE395917T1 (de)
AU (1)	AU2002312815B2 (de)
BR (1)	BR0208221A (de)
CA (1)	CA2441441C (de)
CY (1)	CY1110449T1 (de)
CZ (1)	CZ301423B6 (de)
DE (1)	DE60226710D1 (de)
DK (1)	DK1372652T3 (de)
EA (1)	EA007815B1 (de)
ES (1)	ES2305253T3 (de)
HR (1)	HRPK20030766B3 (de)
HU (1)	HU229258B1 (de)
IL (2)	IL158058A0 (de)
ME (1)	MEP16408A (de)
MX (1)	MXPA03007743A (de)
NO (1)	NO332441B1 (de)
NZ (1)	NZ527655A (de)
PE (1)	PE20020907A1 (de)
PL (1)	PL206118B1 (de)
PT (1)	PT1372652E (de)
RS (1)	RS50681B (de)
SI (1)	SI1372652T1 (de)
SK (1)	SK287481B6 (de)
TW (1)	TWI355935B (de)
UY (1)	UY27220A1 (de)
WO (1)	WO2002076484A2 (de)
ZA (1)	ZA200307381B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60313754T2 (de) *	2002-03-06	2008-01-24	The Medical Research and Education Trust, San Diego	Botanischer extrakt mit antikrebs-aktivität enthaltend isoliquiritigenin
WO2004035034A2 (en) *	2002-10-16	2004-04-29	Ilex Products, Inc.	Clofarabine and taxane chemotherapy combination
BR0316010A (pt) *	2002-11-06	2005-09-13	Cyclacel Ltd	Combinação
EA014231B1 (ru) *	2006-02-10	2010-10-29	НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л.	Комбинации, включающие ингибитор cdk и антитело фактора роста или антимитотик
AU2011330733A1 (en) *	2010-11-19	2013-06-06	Piramal Enterprises Limited	Pharmaceutical combination of paclitaxel and a CDK inhibitor
WO2012131399A1 (en) *	2011-04-01	2012-10-04	Astrazeneca Ab	Therapeutic treatment
PT2785349T (pt)	2011-11-30	2019-12-11	Astrazeneca Ab	Tratamento combinado de cancro
AU2013204533B2 (en)	2012-04-17	2017-02-02	Astrazeneca Ab	Crystalline forms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
MX9102128A (es) *	1990-11-23	1992-07-08	Rhone Poulenc Rorer Sa	Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2697752B1 (fr) *	1992-11-10	1995-04-14	Rhone Poulenc Rorer Sa	Compositions antitumorales contenant des dérivés du taxane.
EP0888458A4 (de) *	1996-02-20	2004-05-06	Sloan Kettering Institutefor C	Kombination von pkc-inhibitoren und therapeutischen agenzien zur behandlung von krebs

2002
- 2002-03-21 US US10/101,947 patent/US20020182204A1/en not_active Abandoned
- 2002-03-21 UY UY27220A patent/UY27220A1/es not_active Application Discontinuation
- 2002-03-22 RS YUP-695/03A patent/RS50681B/sr unknown
- 2002-03-22 DE DE60226710T patent/DE60226710D1/de not_active Expired - Lifetime
- 2002-03-22 MX MXPA03007743A patent/MXPA03007743A/es active IP Right Grant
- 2002-03-22 AU AU2002312815A patent/AU2002312815B2/en not_active Ceased
- 2002-03-22 WO PCT/EP2002/004083 patent/WO2002076484A2/en not_active Ceased
- 2002-03-22 TW TW091105567A patent/TWI355935B/zh not_active IP Right Cessation
- 2002-03-22 HR HR20030766A patent/HRPK20030766B3/xx not_active IP Right Cessation
- 2002-03-22 PT PT02737950T patent/PT1372652E/pt unknown
- 2002-03-22 PL PL367702A patent/PL206118B1/pl not_active IP Right Cessation
- 2002-03-22 SI SI200230711T patent/SI1372652T1/sl unknown
- 2002-03-22 IL IL15805802A patent/IL158058A0/xx unknown
- 2002-03-22 ME MEP-164/08A patent/MEP16408A/xx unknown
- 2002-03-22 NZ NZ527655A patent/NZ527655A/xx not_active IP Right Cessation
- 2002-03-22 JP JP2002574997A patent/JP2004521140A/ja active Pending
- 2002-03-22 HU HU0303589A patent/HU229258B1/hu not_active IP Right Cessation
- 2002-03-22 AR ARP020101061A patent/AR034222A1/es unknown
- 2002-03-22 EA EA200301053A patent/EA007815B1/ru not_active IP Right Cessation
- 2002-03-22 PE PE2002000230A patent/PE20020907A1/es not_active Application Discontinuation
- 2002-03-22 AT AT02737950T patent/ATE395917T1/de active
- 2002-03-22 CA CA002441441A patent/CA2441441C/en not_active Expired - Fee Related
- 2002-03-22 ES ES02737950T patent/ES2305253T3/es not_active Expired - Lifetime
- 2002-03-22 KR KR1020037012338A patent/KR100879712B1/ko not_active Expired - Fee Related
- 2002-03-22 EP EP02737950A patent/EP1372652B1/de not_active Expired - Lifetime
- 2002-03-22 SK SK1169-2003A patent/SK287481B6/sk not_active IP Right Cessation
- 2002-03-22 BR BR0208221-7A patent/BR0208221A/pt not_active Application Discontinuation
- 2002-03-22 CN CNA028070380A patent/CN1498107A/zh active Pending
- 2002-03-22 CZ CZ20032551A patent/CZ301423B6/cs not_active IP Right Cessation
- 2002-03-22 DK DK02737950T patent/DK1372652T3/da active
2003
- 2003-09-16 NO NO20034124A patent/NO332441B1/no not_active IP Right Cessation
- 2003-09-22 IL IL158058A patent/IL158058A/en not_active IP Right Cessation
- 2003-09-22 ZA ZA2003/07381A patent/ZA200307381B/en unknown
2006
- 2006-01-27 US US11/341,840 patent/US20060128640A1/en not_active Abandoned
2008
- 2008-08-11 CY CY20081100843T patent/CY1110449T1/el unknown

Also Published As

Publication number	Publication date
NO332441B1 (no)	2012-09-17
PT1372652E (pt)	2008-07-24
IL158058A (en)	2010-02-17
TWI355935B (en)	2012-01-11
CN1498107A (zh)	2004-05-19
HU229258B1 (en)	2013-10-28
ES2305253T3 (es)	2008-11-01
WO2002076484A2 (en)	2002-10-03
HUP0303589A3 (en)	2007-05-02
MXPA03007743A (es)	2004-11-12
RS50681B (sr)	2010-06-30
CY1110449T1 (el)	2015-04-29
BR0208221A (pt)	2004-03-02
EA007815B1 (ru)	2007-02-27
SI1372652T1 (sl)	2008-10-31
SK287481B6 (sk)	2010-11-08
WO2002076484A3 (en)	2003-01-03
EA200301053A1 (ru)	2004-02-26
UY27220A1 (es)	2002-09-30
KR100879712B1 (ko)	2009-01-22
HUP0303589A2 (hu)	2004-03-01
CZ301423B6 (cs)	2010-02-24
CA2441441C (en)	2009-05-26
EP1372652B1 (de)	2008-05-21
SK11692003A3 (sk)	2004-03-02
AU2002312815B2 (en)	2006-08-24
AR034222A1 (es)	2004-02-04
US20060128640A1 (en)	2006-06-15
CZ20032551A3 (en)	2004-07-14
JP2004521140A (ja)	2004-07-15
DE60226710D1 (de)	2008-07-03
NZ527655A (en)	2006-03-31
ATE395917T1 (de)	2008-06-15
PL206118B1 (pl)	2010-07-30
ZA200307381B (en)	2005-03-30
CA2441441A1 (en)	2002-10-03
PL367702A1 (en)	2005-03-07
IL158058A0 (en)	2004-03-28
KR20030086318A (ko)	2003-11-07
US20020182204A1 (en)	2002-12-05
DK1372652T3 (da)	2008-09-22
NO20034124L (no)	2003-09-16
HRPK20030766B3 (en)	2006-11-30
YU69503A (sh)	2006-08-17
PE20020907A1 (es)	2002-12-19
NO20034124D0 (no)	2003-09-16
HRP20030766A2 (en)	2005-06-30
EP1372652A2 (de)	2004-01-02

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