MX377155B - Variantes de quimosina con propiedades de coagulacion de leche mejoradas. - Google Patents
Variantes de quimosina con propiedades de coagulacion de leche mejoradas.Info
- Publication number
- MX377155B MX377155B MX2019008255A MX2019008255A MX377155B MX 377155 B MX377155 B MX 377155B MX 2019008255 A MX2019008255 A MX 2019008255A MX 2019008255 A MX2019008255 A MX 2019008255A MX 377155 B MX377155 B MX 377155B
- Authority
- MX
- Mexico
- Prior art keywords
- milk clotting
- improved milk
- chymosin variants
- clotting properties
- properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/23—Aspartic endopeptidases (3.4.23)
- C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C11/00—Milk substitutes, e.g. coffee whitener compositions
- A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
- A23C11/10—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins
- A23C11/103—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins containing or not lactose but no other milk components as source of fats, carbohydrates or proteins containing only proteins from pulses, oilseeds or nuts, e.g. nut milk
- A23C11/106—Addition of, or treatment with, microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0326—Rennet produced by fermentation, e.g. microbial rennet; Rennet produced by genetic engineering
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C20/00—Cheese substitutes
- A23C20/02—Cheese substitutes containing neither milk components, nor caseinate, nor lactose, as sources of fats, proteins or carbohydrates
- A23C20/025—Cheese substitutes containing neither milk components, nor caseinate, nor lactose, as sources of fats, proteins or carbohydrates mainly containing proteins from pulses or oilseeds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
- A23C9/1209—Proteolytic or milk coagulating enzymes, e.g. trypsine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
- A23L11/40—Pulse curds
- A23L11/45—Soy bean curds, e.g. tofu
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
- A23L11/60—Drinks from legumes, e.g. lupine drinks
- A23L11/65—Soy drinks
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Agronomy & Crop Science (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Animal Husbandry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Dairy Products (AREA)
- Enzymes And Modification Thereof (AREA)
- Fodder In General (AREA)
- General Preparation And Processing Of Foods (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
La presente invención se refiere a variantes de quimosina con propiedades de coagulación de leche mejoradas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12169503 | 2012-05-25 | ||
| PCT/EP2013/060460 WO2013174840A1 (en) | 2012-05-25 | 2013-05-22 | Variants of chymosin with improved milk-clotting properties |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019008255A MX2019008255A (es) | 2020-01-15 |
| MX377155B true MX377155B (es) | 2025-03-07 |
Family
ID=48577692
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019008255A MX377155B (es) | 2012-05-25 | 2013-05-22 | Variantes de quimosina con propiedades de coagulacion de leche mejoradas. |
| MX2014014300A MX366610B (es) | 2012-05-25 | 2013-05-22 | Variantes de quimosina con propiedades de coagulacion de leche mejoradas. |
| MX2020011941A MX2020011941A (es) | 2012-05-25 | 2014-11-24 | Variantes de quimosina con propiedades de coagulacion de leche mejoradas. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014014300A MX366610B (es) | 2012-05-25 | 2013-05-22 | Variantes de quimosina con propiedades de coagulacion de leche mejoradas. |
| MX2020011941A MX2020011941A (es) | 2012-05-25 | 2014-11-24 | Variantes de quimosina con propiedades de coagulacion de leche mejoradas. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9930899B2 (es) |
| EP (3) | EP2855674B2 (es) |
| JP (3) | JP2015518718A (es) |
| KR (2) | KR102245756B1 (es) |
| CN (2) | CN110714001A (es) |
| AU (3) | AU2013265343B2 (es) |
| BR (2) | BR112014029012B1 (es) |
| CA (3) | CA2874214C (es) |
| DK (2) | DK2855674T4 (es) |
| ES (1) | ES2741723T5 (es) |
| FI (1) | FI2855674T4 (es) |
| HK (1) | HK1202894A1 (es) |
| MX (3) | MX377155B (es) |
| NZ (4) | NZ742745A (es) |
| PL (2) | PL3604509T3 (es) |
| RU (2) | RU2019108268A (es) |
| TR (1) | TR201910420T4 (es) |
| UA (2) | UA118956C2 (es) |
| WO (1) | WO2013174840A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA118956C2 (uk) | 2012-05-25 | 2019-04-10 | Кр. Хансен А/С | Варіант хімозину з поліпшеними молокозгортальними властивостями |
| BR112016017502B1 (pt) | 2014-02-26 | 2023-10-24 | Chr. Hansen A/S | Variantes de polipeptídeo de quimosina isoladas método para a produção das mesmas e método para a fabricação de um produto de alimentação humana ou animal |
| CA2976358A1 (en) | 2015-02-10 | 2016-08-18 | Chr. Hansen A/S | Blends of chymosins with improved milk-clotting properties |
| WO2016207214A1 (en) * | 2015-06-22 | 2016-12-29 | Chr. Hansen A/S | Variants of chymosin with improved properties |
| JP2018525996A (ja) * | 2015-08-31 | 2018-09-13 | セーホーエル．ハンセン アクティーゼルスカブ | 改良された特性を有するキモシンの変異体 |
| AU2017267273B2 (en) | 2016-05-19 | 2021-10-21 | Chr. Hansen A/S | Variants of Chymosin with improved milk-clotting properties |
| CA3024211A1 (en) | 2016-05-19 | 2017-11-23 | Chr. Hansen A/S | Variants of chymosin with improved milk-clotting properties |
| CN106754840B (zh) * | 2016-12-22 | 2019-06-21 | 江南大学 | 一种酶活及热稳定性改善的凝乳酶突变体 |
| EP3740079B1 (en) | 2018-01-15 | 2024-02-21 | Chr. Hansen A/S | Fermented milk product and preparation thereof using phospholipase |
| CN111172139B (zh) * | 2020-02-27 | 2021-11-30 | 武汉轻工大学 | 一种小牛皱胃凝乳酶及基因与菌株和应用 |
| CN113801867B (zh) * | 2021-11-18 | 2022-03-18 | 中国农业科学院生物技术研究所 | 骆驼凝乳酶原突变蛋白及其编码基因和应用 |
| EP4504929A2 (en) | 2022-04-06 | 2025-02-12 | Chr. Hansen A/S | Aspartic protease, methods and uses thereof |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0123928A3 (en) | 1983-03-31 | 1986-02-05 | Codon Genetic Engineering Laboratories | Recombinant dna coding for a polypeptide displaying milk clotting activity |
| US7390936B1 (en) | 1999-08-23 | 2008-06-24 | Sembiosys Genetics Inc. | Commercial production of chymosin in plants |
| RU2192137C2 (ru) * | 2000-08-07 | 2002-11-10 | Открытое акционерное общество "Уфамолагропром" | Способ производства сыра |
| AU2002213838A1 (en) | 2000-11-06 | 2002-05-15 | Chr. Hansen A/S | Method of producing non-bovine chymosin and use thereof |
| MXPA05003493A (es) | 2002-10-02 | 2005-09-30 | Catalyst Biosciences | Metodos para generar y seleccionar proteasas con especificidad alterada. |
| JP4791960B2 (ja) | 2003-06-27 | 2011-10-12 | バイオレン，インク． | ルックスルー突然変異誘発 |
| US7482148B2 (en) | 2004-03-30 | 2009-01-27 | Sudershan Biotech Ltd. | Recombinant calf-chymosin and a process for producing the same |
| US20110008492A1 (en) | 2007-02-13 | 2011-01-13 | Chr. Hansen A/S | Coagulation of milk |
| JP2010046034A (ja) | 2008-08-22 | 2010-03-04 | Toyota Central R&D Labs Inc | 変異体のスクリーニング方法 |
| WO2010110464A1 (en) | 2009-03-24 | 2010-09-30 | Meito Sangyo Co., Ltd. | Improved type milk-clotting protease derived from a microorganism |
| EP3450552A3 (en) * | 2012-05-03 | 2019-05-08 | DSM IP Assets B.V. | Improved enzyme variants |
| UA118956C2 (uk) | 2012-05-25 | 2019-04-10 | Кр. Хансен А/С | Варіант хімозину з поліпшеними молокозгортальними властивостями |
| BR112016017502B1 (pt) | 2014-02-26 | 2023-10-24 | Chr. Hansen A/S | Variantes de polipeptídeo de quimosina isoladas método para a produção das mesmas e método para a fabricação de um produto de alimentação humana ou animal |
| CA2976358A1 (en) | 2015-02-10 | 2016-08-18 | Chr. Hansen A/S | Blends of chymosins with improved milk-clotting properties |
| WO2016207214A1 (en) | 2015-06-22 | 2016-12-29 | Chr. Hansen A/S | Variants of chymosin with improved properties |
| JP2018525996A (ja) | 2015-08-31 | 2018-09-13 | セーホーエル．ハンセン アクティーゼルスカブ | 改良された特性を有するキモシンの変異体 |
| CA3024211A1 (en) | 2016-05-19 | 2017-11-23 | Chr. Hansen A/S | Variants of chymosin with improved milk-clotting properties |
| AU2017267273B2 (en) | 2016-05-19 | 2021-10-21 | Chr. Hansen A/S | Variants of Chymosin with improved milk-clotting properties |
-
2013
- 2013-05-22 UA UAA201413887A patent/UA118956C2/uk unknown
- 2013-05-22 MX MX2019008255A patent/MX377155B/es active IP Right Grant
- 2013-05-22 DK DK13727539.2T patent/DK2855674T4/da active
- 2013-05-22 EP EP13727539.2A patent/EP2855674B2/en active Active
- 2013-05-22 CA CA2874214A patent/CA2874214C/en active Active
- 2013-05-22 AU AU2013265343A patent/AU2013265343B2/en active Active
- 2013-05-22 KR KR1020147036631A patent/KR102245756B1/ko active Active
- 2013-05-22 DK DK19174281.6T patent/DK3604509T3/da active
- 2013-05-22 CN CN201911082253.7A patent/CN110714001A/zh active Pending
- 2013-05-22 NZ NZ742745A patent/NZ742745A/en unknown
- 2013-05-22 TR TR2019/10420T patent/TR201910420T4/tr unknown
- 2013-05-22 HK HK15103493.9A patent/HK1202894A1/xx unknown
- 2013-05-22 MX MX2014014300A patent/MX366610B/es active IP Right Grant
- 2013-05-22 EP EP19174281.6A patent/EP3604509B1/en active Active
- 2013-05-22 BR BR112014029012-1A patent/BR112014029012B1/pt active IP Right Grant
- 2013-05-22 KR KR1020217011988A patent/KR102419515B1/ko active Active
- 2013-05-22 EP EP21164270.7A patent/EP3929288A1/en active Pending
- 2013-05-22 UA UAA201808552A patent/UA126330C2/uk unknown
- 2013-05-22 CA CA3100606A patent/CA3100606C/en active Active
- 2013-05-22 PL PL19174281T patent/PL3604509T3/pl unknown
- 2013-05-22 PL PL13727539.2T patent/PL2855674T5/pl unknown
- 2013-05-22 CN CN201380039107.0A patent/CN104487572B/zh active Active
- 2013-05-22 WO PCT/EP2013/060460 patent/WO2013174840A1/en not_active Ceased
- 2013-05-22 NZ NZ702030A patent/NZ702030A/en unknown
- 2013-05-22 RU RU2019108268A patent/RU2019108268A/ru unknown
- 2013-05-22 FI FIEP13727539.2T patent/FI2855674T4/fi active
- 2013-05-22 RU RU2014152723A patent/RU2683385C2/ru active
- 2013-05-22 BR BR122021019895-0A patent/BR122021019895B1/pt active IP Right Grant
- 2013-05-22 CA CA3201812A patent/CA3201812A1/en active Pending
- 2013-05-22 NZ NZ725398A patent/NZ725398A/en unknown
- 2013-05-22 US US14/402,567 patent/US9930899B2/en active Active
- 2013-05-22 NZ NZ742660A patent/NZ742660A/en unknown
- 2013-05-22 ES ES13727539T patent/ES2741723T5/es active Active
- 2013-05-22 JP JP2015513145A patent/JP2015518718A/ja active Pending
-
2014
- 2014-11-24 MX MX2020011941A patent/MX2020011941A/es unknown
-
2018
- 2018-02-20 US US15/900,603 patent/US10806157B2/en active Active
- 2018-06-06 JP JP2018108935A patent/JP2018148926A/ja active Pending
-
2019
- 2019-05-21 AU AU2019203589A patent/AU2019203589B2/en active Active
- 2019-12-18 JP JP2019228446A patent/JP2020058367A/ja active Pending
-
2022
- 2022-02-02 AU AU2022200663A patent/AU2022200663B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |