MY100777A - Pyridinylpiperazine derivatives - Google Patents

Pyridinylpiperazine derivatives

Info

Publication number: MY100777A
Authority: MY; Malaysia
Prior art keywords: furo; substituent; piperazinyl; derivatives; antipsychotic
Prior art date: 1985-05-06

Application number

MYPI87002712A

Other languages

English (en)

Inventor

Stewart New James

P Yevice Joseph

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-06

Filing date

1987-10-01

Publication date

1991-02-14

1987-10-01 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1991-02-14 Publication of MY100777A publication Critical patent/MY100777A/en

Links

GZRKXKUVVPSREJ-UHFFFAOYSA-N pyridinylpiperazine Chemical class C1CNCCN1C1=CC=CC=N1 GZRKXKUVVPSREJ-UHFFFAOYSA-N 0.000 title 1
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
230000000561 anti-psychotic effect Effects 0.000 abstract 2
QBICJHHCQYFVMI-UHFFFAOYSA-N 4-[4-(4-furo[3,2-c]pyridin-4-ylpiperazin-1-yl)butyl]morpholine-3,5-dione Chemical compound O=C1COCC(=O)N1CCCCN1CCN(C=2C=3C=COC=3C=CN=2)CC1 QBICJHHCQYFVMI-UHFFFAOYSA-N 0.000 abstract 1
229940123464 Thiazolidinedione Drugs 0.000 abstract 1
239000003420 antiserotonin agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000003949 imides Chemical class 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
150000001467 thiazolidinediones Chemical class 0.000 abstract 1
DBDCNCCRPKTRSD-UHFFFAOYSA-N thieno[3,2-b]pyridine Chemical compound C1=CC=C2SC=CC2=N1 DBDCNCCRPKTRSD-UHFFFAOYSA-N 0.000 abstract 1
229940125670 thienopyridine Drugs 0.000 abstract 1
239000002175 thienopyridine Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

MYPI87002712A 1985-05-06 1987-10-01 Pyridinylpiperazine derivatives MY100777A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73120185A	1985-05-06	1985-05-06

Publications (1)

Publication Number	Publication Date
MY100777A true MY100777A (en)	1991-02-14

Family

ID=24938510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI87002712A MY100777A (en)	1985-05-06	1987-10-01	Pyridinylpiperazine derivatives

Country Status (25)

Country	Link
JP (1)	JPH0753728B2 (de)
KR (1)	KR940000829B1 (de)
CN (1)	CN1017901B (de)
AT (1)	AT398572B (de)
AU (1)	AU593244B2 (de)
BE (1)	BE904724A (de)
CA (1)	CA1278792C (de)
CH (1)	CH672787A5 (de)
DE (1)	DE3615180C2 (de)
DK (1)	DK165745C (de)
EG (1)	EG18206A (de)
ES (6)	ES8801250A1 (de)
FI (1)	FI85484C (de)
FR (1)	FR2581385B1 (de)
GB (1)	GB2174703B (de)
GR (1)	GR861149B (de)
HU (1)	HU195509B (de)
IE (1)	IE59201B1 (de)
IT (1)	IT1208607B (de)
LU (1)	LU86421A1 (de)
MY (1)	MY100777A (de)
NL (1)	NL8601146A (de)
PT (1)	PT82523B (de)
SE (1)	SE465270B (de)
ZA (1)	ZA862046B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5801186A (en) *	1987-11-20	1998-09-01	Hoechst Marion Roussel, Inc.	3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
US4880930A (en) *	1987-11-30	1989-11-14	New James S	Psychotropic acyclic amide derivatives
US4780466A (en) *	1988-03-17	1988-10-25	Hoechst-Roussel Pharmaceuticals, Inc.	Arylpiperazinylalkoxy derivatives of cyclic imides
IE903410A1 (en) *	1989-10-09	1991-04-10	Novo Nordisk As	Indole derivatives, their preparation and use
US5272148A (en) *	1992-09-09	1993-12-21	Hoechst-Roussel Pharmaceuticals Incorporated	Heteroarenylpiperazines
BR9610579A (pt) *	1995-09-15	1999-07-06	Sanofi Synthelabo	Derivados de quinolein-2(1H)-ona como antagonistas da serotonina
FR2738823B1 (fr) *	1995-09-15	1997-10-31	Synthelabo	Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique
FR2738822B1 (fr) *	1995-09-15	1997-10-31	Synthelabo	Derives de 4-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)quinolein-2(1h)-one, leur preparation et leur application en therapeutique
FR2738824B1 (fr) *	1995-09-15	1997-10-31	Synthelabo	Derives de 3-(omega(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1 -yl)alkyl)-3,4-dihydroquinazolin-2(1h)-one,leur preparation et leur application en therapeutique
FR2761071B1 (fr) *	1997-03-20	1999-12-03	Synthelabo	Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
FR2797874B1 (fr) *	1999-08-27	2002-03-29	Adir	Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20040077605A1 (en)	2001-06-20	2004-04-22	Salvati Mark E.	Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4367335A (en) *	1981-08-03	1983-01-04	Mead Johnson & Company	Thiazolidinylalkylene piperazine derivatives
US4452799A (en) *	1981-12-23	1984-06-05	Mead Johnson & Company	Benzisothiazole and benzisoxazole piperazine derivatives
US4361565A (en) *	1981-12-28	1982-11-30	Mead Johnson & Company	2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines

1986
- 1986-03-11 CA CA000503794A patent/CA1278792C/en not_active Expired - Fee Related
- 1986-03-19 ZA ZA862046A patent/ZA862046B/xx unknown
- 1986-04-29 GR GR861149A patent/GR861149B/el unknown
- 1986-04-29 EG EG250/86A patent/EG18206A/xx active
- 1986-04-29 AU AU56795/86A patent/AU593244B2/en not_active Expired
- 1986-04-30 FI FI861820A patent/FI85484C/fi not_active IP Right Cessation
- 1986-05-02 GB GB08610810A patent/GB2174703B/en not_active Expired
- 1986-05-02 KR KR1019860003445A patent/KR940000829B1/ko not_active Expired - Fee Related
- 1986-05-05 CH CH1830/86A patent/CH672787A5/de not_active IP Right Cessation
- 1986-05-05 FR FR8606471A patent/FR2581385B1/fr not_active Expired - Lifetime
- 1986-05-05 CN CN86103071A patent/CN1017901B/zh not_active Expired
- 1986-05-05 IE IE119386A patent/IE59201B1/en not_active IP Right Cessation
- 1986-05-05 SE SE8602061A patent/SE465270B/sv not_active IP Right Cessation
- 1986-05-05 NL NL8601146A patent/NL8601146A/nl active Search and Examination
- 1986-05-05 DE DE3615180A patent/DE3615180C2/de not_active Expired - Lifetime
- 1986-05-05 DK DK207186A patent/DK165745C/da not_active IP Right Cessation
- 1986-05-05 BE BE0/216623A patent/BE904724A/fr not_active IP Right Cessation
- 1986-05-05 LU LU86421A patent/LU86421A1/fr unknown
- 1986-05-05 ES ES554659A patent/ES8801250A1/es not_active Expired
- 1986-05-06 IT IT8620313A patent/IT1208607B/it active
- 1986-05-06 HU HU861860A patent/HU195509B/hu unknown
- 1986-05-06 AT AT0121486A patent/AT398572B/de not_active IP Right Cessation
- 1986-05-06 JP JP61103726A patent/JPH0753728B2/ja not_active Expired - Lifetime
- 1986-05-06 PT PT82523A patent/PT82523B/pt unknown
1987
- 1987-09-25 ES ES557757A patent/ES8802149A1/es not_active Expired
- 1987-10-01 MY MYPI87002712A patent/MY100777A/en unknown
1988
- 1988-01-28 ES ES557809A patent/ES8802614A1/es not_active Expired
- 1988-05-26 ES ES557839A patent/ES8900138A1/es not_active Expired
- 1988-11-16 ES ES557855A patent/ES8900253A1/es not_active Expired
1989
- 1989-02-27 ES ES557865A patent/ES9000005A1/es not_active Expired

Also Published As

Publication number	Publication date
EG18206A (en)	1992-09-30
ZA862046B (en)	1986-11-26
ES554659A0 (es)	1987-12-16
IE59201B1 (en)	1994-01-26
CN1017901B (zh)	1992-08-19
CH672787A5 (de)	1989-12-29
ES9000005A1 (es)	1989-11-01
ES557839A0 (es)	1989-01-16
KR940000829B1 (ko)	1994-02-02
DE3615180A1 (de)	1986-11-06
FI85484B (fi)	1992-01-15
FI85484C (fi)	1992-04-27
JPH0753728B2 (ja)	1995-06-07
SE8602061D0 (sv)	1986-05-05
IE861193L (en)	1986-11-06
SE465270B (sv)	1991-08-19
FI861820A0 (fi)	1986-04-30
PT82523B (pt)	1988-10-14
ATA121486A (de)	1994-05-15
GB2174703A (en)	1986-11-12
ES557855A0 (es)	1989-05-16
ES8802149A1 (es)	1988-04-01
ES557809A0 (es)	1988-09-01
SE8602061L (sv)	1986-11-07
KR860009008A (ko)	1986-12-19
ES8801250A1 (es)	1987-12-16
DK207186D0 (da)	1986-05-05
DE3615180C2 (de)	1996-03-07
LU86421A1 (fr)	1986-12-05
FR2581385A1 (fr)	1986-11-07
DK165745C (da)	1993-06-14
AT398572B (de)	1994-12-27
ES8900138A1 (es)	1989-01-16
ES8802614A1 (es)	1988-09-01
BE904724A (fr)	1986-11-05
NL8601146A (nl)	1986-12-01
JPS61268681A (ja)	1986-11-28
GB2174703B (en)	1988-10-26
HU195509B (en)	1988-05-30
CN86103071A (zh)	1987-03-18
ES557757A0 (es)	1988-04-01
ES8900253A1 (es)	1989-05-16
FI861820A7 (fi)	1986-11-07
DK165745B (da)	1993-01-11
GB8610810D0 (en)	1986-06-11
IT1208607B (it)	1989-07-10
GR861149B (en)	1986-09-09
IT8620313A0 (it)	1986-05-06
FR2581385B1 (fr)	1991-10-04
DK207186A (da)	1986-11-07
HUT43848A (en)	1987-12-28
AU593244B2 (en)	1990-02-08
CA1278792C (en)	1991-01-08
PT82523A (en)	1986-06-01
AU5679586A (en)	1986-11-13

Publication	Publication Date	Title
YU115588A (en)	1988-10-31	Process for obtaining derivatives of pyrimidanone as calcium independent camp inhibitors of phosphodiestheraze
ES8701173A1 (es)	1986-12-01	Procedimiento para la fabricacion de derivados de pirazol tienil condensados
ATE119774T1 (de)	1995-04-15	Imidazopyridinderivate und ihre verwendung.
DK0436334T3 (da)	1995-02-13	3-Aminopiperidinderivater og beslægtede nitrogenholdige heterocycliske forbindelser
AU6358986A (en)	1987-04-09	New quinazoline derivatives and a process for their production
ES8801250A1 (es)	1987-12-16	Un procedimiento para la preparacion de derivados de piperazimilo 1,4-di sustituidos.
DE3777735D1 (de)	1992-04-30	Imid-derivate, ihre herstellung und ihre verwendung.
ATE112558T1 (de)	1994-10-15	Glycosidasehemmer.
NO305973B1 (no)	1999-08-30	Anvendelse av quinolin og quinazolinderivater, forbindelsene som sådanne samt antiinflammatoriske midler inneholdende forbindelsene
ES8705869A1 (es)	1987-05-16	Un procedimiento para la preparacion de derivados de piperazina 1,4-disustituidos.
EP0275482A3 (en)	1988-12-28	Novel prolinal derivatives
DE68903226D1 (de)	1992-11-26	Dideoxydidehydrocarbocyclische nukleoside.
BE902847A (fr)	1986-01-10	Nouvelles isoindolinylalcoylpiperazines
EP0162776A3 (en)	1987-05-06	Heterocyclic derivatives, process for their preparation and medicaments useful as aldose reductase inhibitors containing them
EP0253468A3 (en)	1989-06-14	Six-membered heterocyclic derivatives of n'substituted-n,n'-diacylhydrazines
GB8823475D0 (en)	1988-11-16	Chemical compounds
ATE112569T1 (de)	1994-10-15	Verwendung von imidazopyrazolderivaten als analgesische und antiinflammatorische mittel.
MY104207A (en)	1994-02-28	Antipsychotic 4-[4-(3-benzisothiazolyl)-1- piperazinyl]butyl bridged bicyclic imides.
EP0273017A3 (en)	1989-03-01	N-alkyl derivatives of 2-amino-6,7-dimethoxy tetraline, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same
EP0486687A4 (en)	1992-06-17	Quinolonecarboxylic acid derivatives
GR861696B (en)	1986-10-30	Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl) pyridines
TW257758B (en)	1995-09-21	Piperazine derivatives (1)
ES549788A0 (es)	1986-03-16	Procedimiento de preparacion de derivados de 4-(bis(4-fluo- rofenil)metilen)-piperidina