MY128007A - Thiazolidinedione derivative and its use as antidiabetic - Google Patents

Thiazolidinedione derivative and its use as antidiabetic

Info

Publication number: MY128007A
Authority: MY; Malaysia
Prior art keywords: provides; compound; containing peaks; set out; spectrum containing
Prior art date: 1999-04-23

Application number

MYPI20001707A

Other languages

English (en)

Inventor

Paul David James Blackler

Robert Gordon Giles

Michael John Sasse

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-23

Filing date

2000-04-21

Publication date

2007-01-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315460&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY128007(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-04-23 Priority claimed from GBGB9909472.4A external-priority patent/GB9909472D0/en

1999-05-25 Priority claimed from GBGB9912197.2A external-priority patent/GB9912197D0/en

2000-04-21 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2007-01-31 Publication of MY128007A publication Critical patent/MY128007A/en

Links

230000003178 anti-diabetic effect Effects 0.000 title 1
239000003472 antidiabetic agent Substances 0.000 title 1
150000001467 thiazolidinediones Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
238000000634 powder X-ray diffraction Methods 0.000 abstract 2
238000001237 Raman spectrum Methods 0.000 abstract 1
YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 abstract 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical class OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000000279 solid-state nuclear magnetic resonance spectrum Methods 0.000 abstract 1
238000001228 spectrum Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

MYPI20001707A 1999-04-23 2000-04-21 Thiazolidinedione derivative and its use as antidiabetic MY128007A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9909472.4A GB9909472D0 (en)	1999-04-23	1999-04-23	Novel compounds
GBGB9912197.2A GB9912197D0 (en)	1999-05-25	1999-05-25	Novel pharmaceutical

Publications (1)

Publication Number	Publication Date
MY128007A true MY128007A (en)	2007-01-31

Family

ID=26315460

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI20001707A MY128007A (en)	1999-04-23	2000-04-21	Thiazolidinedione derivative and its use as antidiabetic

Country Status (40)

Country	Link
US (2)	US6815457B1 (fr)
EP (3)	EP1903043A1 (fr)
JP (1)	JP2002543075A (fr)
KR (1)	KR100744359B1 (fr)
CN (1)	CN1208335C (fr)
AP (1)	AP1495A (fr)
AR (2)	AR023568A1 (fr)
AT (2)	ATE382046T1 (fr)
AU (1)	AU765498B2 (fr)
BG (1)	BG65427B1 (fr)
BR (1)	BR0009934A (fr)
CA (1)	CA2370258A1 (fr)
CO (1)	CO5170424A1 (fr)
CY (1)	CY1107238T1 (fr)
CZ (1)	CZ20013799A3 (fr)
DE (2)	DE60037602T2 (fr)
DK (2)	DK1173434T3 (fr)
DZ (1)	DZ3155A1 (fr)
EA (1)	EA004534B1 (fr)
ES (2)	ES2298327T3 (fr)
HK (1)	HK1045154B (fr)
HR (1)	HRP20010773B1 (fr)
HU (1)	HUP0200929A3 (fr)
IL (1)	IL146110A0 (fr)
MA (1)	MA26785A1 (fr)
MX (1)	MXPA01010820A (fr)
MY (1)	MY128007A (fr)
NO (1)	NO320589B1 (fr)
NZ (1)	NZ515163A (fr)
OA (1)	OA11871A (fr)
PE (1)	PE20010040A1 (fr)
PL (1)	PL351686A1 (fr)
PT (2)	PT1284268E (fr)
RS (1)	RS50114B (fr)
SK (1)	SK286423B6 (fr)
TR (1)	TR200103061T2 (fr)
TW (1)	TW591027B (fr)
UA (1)	UA67843C2 (fr)
UY (1)	UY26120A1 (fr)
WO (1)	WO2000064892A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9726568D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US20020137940A1 (en) *	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
CN1167702C (zh)	1999-04-23	2004-09-22	史密丝克莱恩比彻姆有限公司	5-[4-[2-n-甲基-n-(2-吡啶基)氨基]乙氧基]苄基]噻唑烷-2,4-二酮马来酸盐的多晶型物
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
RS50114B (sr)	1999-04-23	2009-03-25	Smithkline Beecham P.L.C.,	Novi polimorfni oblik 5-/4-/2-(n-metil- n-(2-piridil)amino/ etoksi/benzil/ tiazolidin-2,4-dion, soli maleinske kiseline
GB0006133D0 (en)	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
US7241895B2 (en) *	2000-09-26	2007-07-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
AU9123201A (en) *	2000-09-26	2002-04-08	Reddy S Res Foundation	Novel polymorphic forms of 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,4-dione maleate and process for their preparation
WO2003050116A1 (fr) *	2001-12-13	2003-06-19	Smithkline Beecham Plc	Sel d'acide 10-camphorsulphonique de 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione et son utilisation contre le diabete sucre
GB0130511D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
WO2003053962A1 (fr) *	2001-12-20	2003-07-03	Smithkline Beecham Plc	Sel d'acide malique 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy) benzyl) thiazolidine-2, 4-dione et son utilisation contre le diabete sucre
GB0307259D0 (en) *	2003-03-28	2003-05-07	Glaxo Group Ltd	Process
EP1468997A3 (fr) *	2003-04-18	2004-11-03	CHEMI S.p.A.	Formes polymorphes de maléate de rosiglitatone
GB2405403A (en) *	2003-08-29	2005-03-02	Cipla Ltd	Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
EP1709038A2 (fr) *	2004-01-28	2006-10-11	Usv Limited	Procede de preparation de maleate de 5- 4- 2- n-methyl-n-(2-pyridyl) amino¨ ethoxy¨ phenyl methyl¨ thiazolidine-2, 4-dione
ITMI20041537A1 (it) *	2004-07-28	2004-10-28	Chemi Spa	Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) *	2005-05-24	2007-09-26	Zentiva, A. S.	Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
US7435741B2 (en) *	2006-05-09	2008-10-14	Teva Pharmaceutical Industries, Ltd.	2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
US20090076093A1 (en) *	2007-09-14	2009-03-19	Protia, Llc	Deuterium-enriched rosiglitazone
EP2184055A1 (fr)	2008-11-07	2010-05-12	LEK Pharmaceuticals d.d.	Procédé de préparation de formes galéniques solides de maléate de rosiglitazone

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0842925A1 (fr)	1987-09-04	1998-05-20	Beecham Group Plc	Thiazolidinédiones substituées
US6288095B1 (en)	1987-09-04	2001-09-11	Beecham Group P.L.C.	Compounds
GB9124513D0 (en)	1991-11-19	1992-01-08	Smithkline Beecham Plc	Novel process
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5741803A (en)	1992-09-05	1998-04-21	Smithkline Beecham Plc	Substituted thiazolidinedionle derivatives
US5457109A (en) *	1993-09-15	1995-10-10	Warner-Lambert Company	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
DE4404198A1 (de)	1994-02-10	1995-08-17	Henkel Kgaa	2-Fluor-6-nitroaniline
SG47100A1 (en)	1994-02-10	1998-03-20	Smithkline Beecham Plc	Use of insulin sensitisers for treating renal diseases
US20010044458A1 (en) *	1994-02-10	2001-11-22	Smithkline Beechamp P.L.C.	Use of insulin sensitisers for treating renal diseases
TWI238064B (en) *	1995-06-20	2005-08-21	Takeda Chemical Industries Ltd	A pharmaceutical composition for prophylaxis and treatment of diabetes
US6153632A (en) *	1997-02-24	2000-11-28	Rieveley; Robert B.	Method and composition for the treatment of diabetes
GB9711683D0 (en)	1997-06-05	1997-08-06	Smithkline Beecham Plc	Composition
GB9712866D0 (en)	1997-06-18	1997-08-20	Smithkline Beecham Plc	Novel method of treatment
US20020004515A1 (en) *	1997-06-18	2002-01-10	Smith Stephen Alistair	Treatment of diabetes with thiazolidinedione and metformin
CN1168451C (zh)	1997-06-18	2004-09-29	史密丝克莱恩比彻姆有限公司	噻唑烷二酮和磺酰脲组合物在制备治疗糖尿病的药物中的用途
CN1114404C (zh)	1997-06-18	2003-07-16	史密丝克莱恩比彻姆有限公司	用噻唑烷二酮和二甲双胍治疗糖尿病
US20020028768A1 (en) *	1997-06-18	2002-03-07	Smithkline Beecham P.L.C.	Treatment of diabetes with rosiglitazone and insulin
US20010049380A1 (en) *	1997-06-18	2001-12-06	Smith Stephen Alistair	Treatment of diabetes with thiazolidinedione and sulphonylurea
CA2294134A1 (fr)	1997-06-18	1998-12-23	Stephen Alistair Smith	Traitement du diabete a l'aide de thiazolidinedione et d'un inhibiteur des alpha-glucosidases
US20020045649A1 (en) *	1997-07-18	2002-04-18	Smithkline Beecham P.L.C.	Treatment of diabetes with thiazolidinedione and sulphonylurea
US20020016287A1 (en) *	1997-07-18	2002-02-07	Smithkline Beecham P.L.C.	Treatment of diabetes with thiazolidinedione, insulin secretagogue and diguanide
GB9726568D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
GB9726566D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US20020137940A1 (en)	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726563D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
RS50114B (sr)	1999-04-23	2009-03-25	Smithkline Beecham P.L.C.,	Novi polimorfni oblik 5-/4-/2-(n-metil- n-(2-piridil)amino/ etoksi/benzil/ tiazolidin-2,4-dion, soli maleinske kiseline
EA003031B1 (ru)	1999-04-23	2002-12-26	Смитклайн Бичам Плс	Новый фармацевтический препарат
CN1167702C (zh)	1999-04-23	2004-09-22	史密丝克莱恩比彻姆有限公司	5-[4-[2-n-甲基-n-(2-吡啶基)氨基]乙氧基]苄基]噻唑烷-2,4-二酮马来酸盐的多晶型物
AU9123201A (en)	2000-09-26	2002-04-08	Reddy S Res Foundation	Novel polymorphic forms of 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,4-dione maleate and process for their preparation

2000
- 2000-04-19 RS YUP-752/01A patent/RS50114B/sr unknown
- 2000-04-19 AR ARP000101870A patent/AR023568A1/es unknown
- 2000-04-19 AP APAP/P/2001/002333A patent/AP1495A/en active
- 2000-04-19 JP JP2000614244A patent/JP2002543075A/ja active Pending
- 2000-04-19 PT PT02080320T patent/PT1284268E/pt unknown
- 2000-04-19 HR HR20010773A patent/HRP20010773B1/xx not_active IP Right Cessation
- 2000-04-19 US US10/030,323 patent/US6815457B1/en not_active Expired - Fee Related
- 2000-04-19 OA OA1200100275A patent/OA11871A/en unknown
- 2000-04-19 CZ CZ20013799A patent/CZ20013799A3/cs unknown
- 2000-04-19 WO PCT/GB2000/001514 patent/WO2000064892A2/fr not_active Ceased
- 2000-04-19 DK DK00920889T patent/DK1173434T3/da active
- 2000-04-19 CA CA002370258A patent/CA2370258A1/fr not_active Abandoned
- 2000-04-19 DK DK02080320T patent/DK1284268T3/da active
- 2000-04-19 UA UA2001117938A patent/UA67843C2/uk unknown
- 2000-04-19 KR KR1020017013557A patent/KR100744359B1/ko not_active Expired - Fee Related
- 2000-04-19 PL PL00351686A patent/PL351686A1/xx not_active Application Discontinuation
- 2000-04-19 SK SK1491-2001A patent/SK286423B6/sk not_active IP Right Cessation
- 2000-04-19 AT AT02080320T patent/ATE382046T1/de not_active IP Right Cessation
- 2000-04-19 AR ARP000101865A patent/AR023564A1/es unknown
- 2000-04-19 DZ DZ003155A patent/DZ3155A1/fr active
- 2000-04-19 AT AT00920889T patent/ATE247653T1/de not_active IP Right Cessation
- 2000-04-19 HK HK02104882.1A patent/HK1045154B/en not_active IP Right Cessation
- 2000-04-19 MX MXPA01010820A patent/MXPA01010820A/es unknown
- 2000-04-19 EP EP07150378A patent/EP1903043A1/fr not_active Withdrawn
- 2000-04-19 ES ES02080320T patent/ES2298327T3/es not_active Expired - Lifetime
- 2000-04-19 DE DE60037602T patent/DE60037602T2/de not_active Expired - Fee Related
- 2000-04-19 HU HU0200929A patent/HUP0200929A3/hu not_active IP Right Cessation
- 2000-04-19 BR BR0009934-1A patent/BR0009934A/pt not_active Application Discontinuation
- 2000-04-19 NZ NZ515163A patent/NZ515163A/xx unknown
- 2000-04-19 CN CNB008090572A patent/CN1208335C/zh not_active Expired - Fee Related
- 2000-04-19 EP EP02080320A patent/EP1284268B1/fr not_active Expired - Lifetime
- 2000-04-19 PT PT00920889T patent/PT1173434E/pt unknown
- 2000-04-19 EP EP00920889A patent/EP1173434B1/fr not_active Expired - Lifetime
- 2000-04-19 AU AU41306/00A patent/AU765498B2/en not_active Ceased
- 2000-04-19 EA EA200101119A patent/EA004534B1/ru not_active IP Right Cessation
- 2000-04-19 TR TR2001/03061T patent/TR200103061T2/xx unknown
- 2000-04-19 IL IL14611000A patent/IL146110A0/xx unknown
- 2000-04-19 DE DE60004658T patent/DE60004658T2/de not_active Expired - Fee Related
- 2000-04-19 ES ES00920889T patent/ES2204557T3/es not_active Expired - Lifetime
- 2000-04-19 CO CO00028932A patent/CO5170424A1/es not_active Application Discontinuation
- 2000-04-19 PE PE2000000364A patent/PE20010040A1/es not_active Application Discontinuation
- 2000-04-21 MY MYPI20001707A patent/MY128007A/en unknown
- 2000-04-24 TW TW089107633A patent/TW591027B/zh not_active IP Right Cessation
- 2000-04-24 UY UY26120A patent/UY26120A1/es not_active Application Discontinuation
2001
- 2001-10-22 MA MA26377A patent/MA26785A1/fr unknown
- 2001-10-22 NO NO20015149A patent/NO320589B1/no unknown
- 2001-11-20 BG BG106119A patent/BG65427B1/bg unknown
2003
- 2003-11-07 US US10/703,887 patent/US20040092555A1/en not_active Abandoned
2008
- 2008-03-12 CY CY20081100277T patent/CY1107238T1/el unknown

Also Published As

Publication number	Publication date
DE60004658D1 (de)	2003-09-25
EP1903043A1 (fr)	2008-03-26
YU75201A (sh)	2004-09-03
PT1284268E (pt)	2008-03-10
CY1107238T1 (el)	2012-11-21
HRP20010773B1 (en)	2005-06-30
BG106119A (en)	2002-05-31
HRP20010773A2 (en)	2002-10-31
DE60037602D1 (de)	2008-02-07
EA200101119A1 (ru)	2002-04-25
WO2000064892A2 (fr)	2000-11-02
DE60004658T2 (de)	2004-06-24
JP2002543075A (ja)	2002-12-17
SK14912001A3 (sk)	2002-02-05
DZ3155A1 (fr)	2000-11-02
NO320589B1 (no)	2005-12-27
NZ515163A (en)	2004-02-27
EP1284268A1 (fr)	2003-02-19
HK1045154B (en)	2004-06-25
CZ20013799A3 (cs)	2002-04-17
TR200103061T2 (tr)	2002-05-21
UA67843C2 (uk)	2004-07-15
HUP0200929A3 (en)	2004-03-29
RS50114B (sr)	2009-03-25
WO2000064892A3 (fr)	2001-01-25
BG65427B1 (bg)	2008-07-31
HK1045154A1 (en)	2002-11-15
HUP0200929A2 (en)	2002-08-28
AU765498B2 (en)	2003-09-18
SK286423B6 (sk)	2008-09-05
OA11871A (en)	2006-03-27
PL351686A1 (en)	2003-06-02
EP1173434B1 (fr)	2003-08-20
ES2298327T3 (es)	2008-05-16
US20040092555A1 (en)	2004-05-13
CA2370258A1 (fr)	2000-11-02
CN1208335C (zh)	2005-06-29
KR100744359B1 (ko)	2007-07-30
NO20015149L (no)	2001-12-17
NO20015149D0 (no)	2001-10-22
CN1355801A (zh)	2002-06-26
UY26120A1 (es)	2000-12-29
KR20020028873A (ko)	2002-04-17
IL146110A0 (en)	2002-07-25
HK1055293A1 (en)	2004-01-02
AR023568A1 (es)	2002-09-04
US6815457B1 (en)	2004-11-09
EA004534B1 (ru)	2004-06-24
DK1173434T3 (da)	2003-12-08
EP1173434A2 (fr)	2002-01-23
AU4130600A (en)	2000-11-10
ATE247653T1 (de)	2003-09-15
EP1284268B1 (fr)	2007-12-26
ATE382046T1 (de)	2008-01-15
MA26785A1 (fr)	2004-12-20
ES2204557T3 (es)	2004-05-01
PT1173434E (pt)	2003-12-31
MXPA01010820A (es)	2002-06-04
AP1495A (en)	2005-11-30
AR023564A1 (es)	2002-09-04
TW591027B (en)	2004-06-11
CO5170424A1 (es)	2002-06-27
PE20010040A1 (es)	2001-03-10
DE60037602T2 (de)	2009-01-08
DK1284268T3 (da)	2008-04-28
BR0009934A (pt)	2002-06-04

Publication	Publication Date	Title
MY128007A (en)	2007-01-31	Thiazolidinedione derivative and its use as antidiabetic
NZ515168A (en)	2004-02-27	Polymorph of 5-[4-[2- (n-methyl-n-( 2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt
YU36400A (sh)	2003-12-31	Supstituisani tiazolidinedion derivat, postupak za njegovo dobijanje i njegova farmaceutska primena
MY135612A (en)	2008-05-30	Novel pharmaceutical
AP1607A (en)	2006-05-03	Thiazolidinedione derivative and its use as antidiabetic.
AP1441A (en)	2005-07-30	Hydrate of 5- [4-{2-(N-methlyl-N-(2-pyridil) amino) ethoxy} benzyl] thiazolidine-2,4-dione maleic acid salt.
MY126034A (en)	2006-09-29	Thiazolidinedione derivative and its use as antidiabetic
NZ515164A (en)	2004-02-27	Thiazolidinedione derivative and its use as antidiabetic
AU2001284285A1 (en)	2002-03-22	A thiazolidinedione derivative and its use as antidiabetic
ECSP003438A (es)	2000-06-19	Nuevos compuestos
ECSP982780A (es)	1999-05-17	Nuevo producto farmaceutico proceso para su preparacion y su uso en medicina
ECSP003434A (es)	2000-07-21	Nuevos compuestos