MY8600700A - Aroylimidazolones and analogues thereof - Google Patents

Aroylimidazolones and analogues thereof

Info

Publication number
MY8600700A
MY8600700A MY700/86A MY8600700A MY8600700A MY 8600700 A MY8600700 A MY 8600700A MY 700/86 A MY700/86 A MY 700/86A MY 8600700 A MY8600700 A MY 8600700A MY 8600700 A MY8600700 A MY 8600700A
Authority
MY
Malaysia
Prior art keywords
aroylimidazolones
analogues
aroylimidazole
cardiotonics
ones
Prior art date
Application number
MY700/86A
Other languages
English (en)
Inventor
Richard C Dage
Frank P Palopoli
Richard A Schettler
J Martin Grisar
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of MY8600700A publication Critical patent/MY8600700A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Luminescent Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
MY700/86A 1981-03-05 1986-12-30 Aroylimidazolones and analogues thereof MY8600700A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24088981A 1981-03-05 1981-03-05
US06/314,312 US4405628A (en) 1981-03-05 1981-10-23 4-Pyridylimidazolones and method of use

Publications (1)

Publication Number Publication Date
MY8600700A true MY8600700A (en) 1986-12-31

Family

ID=26933806

Family Applications (1)

Application Number Title Priority Date Filing Date
MY700/86A MY8600700A (en) 1981-03-05 1986-12-30 Aroylimidazolones and analogues thereof

Country Status (18)

Country Link
US (1) US4405628A (de)
EP (1) EP0059948B1 (de)
KR (1) KR890000765B1 (de)
AT (1) ATE16489T1 (de)
AU (1) AU557590B2 (de)
CA (1) CA1190550A (de)
DE (1) DE3267352D1 (de)
DK (1) DK168627B1 (de)
ES (2) ES8305352A1 (de)
GB (1) GB2096600B (de)
GR (1) GR76518B (de)
HK (1) HK61686A (de)
IE (1) IE52387B1 (de)
IL (1) IL65137A (de)
MY (1) MY8600700A (de)
NO (1) NO157175C (de)
NZ (1) NZ199885A (de)
PH (1) PH18345A (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4552880A (en) * 1983-02-15 1985-11-12 Merrell Dow Pharmaceuticals Inc. Aroylimidazolones
US4532250A (en) * 1983-11-23 1985-07-30 American Hospital Supply Corporation 5-Heteroarylimidazol-2-ones having cardiotonic activity
US4556665A (en) * 1984-07-09 1985-12-03 Schering A.G. Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
US4803278A (en) * 1984-07-30 1989-02-07 Merrell Dow Pharmaceuticals, Inc. Preparation of 1,3-dihydro-4-pyridoyl-2H-imidazol-2-ones
CA1262732A (en) * 1984-07-30 1989-11-07 Richard A. Schnettler Preparation of 1,3-dihydro-4-pyridoyl-2h-imidazol-2- ones
US4999365A (en) * 1987-03-20 1991-03-12 Merrell Dow Pharmaceuticals Inc. Method of reducing reperfusion injury with imidazol-2-thiones
ZA881807B (en) * 1987-03-20 1988-09-05 Merrell Dow Pharmaceuticals Inc. Method for reducing reperfusion injury with imidazol-2-thiones
ZA887662B (en) * 1987-10-19 1989-06-28 Merrell Dow Pharma Method for reducing reperfusion injury with imidazol-2-thione-carboxamides
AU8212491A (en) * 1990-06-29 1992-01-23 Upjohn Company, The Substituted 1-(alkoxyphenyl)piperazines with cns and antihypertensive activity
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (de) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (ru) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. Способ получения агонистов гуанилатциклазы c
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
EP3492106B1 (de) 2013-08-09 2021-02-17 Ardelyx, Inc. Verbindungen und verfahren zur hemmung eines phosphattransports
EP3972599B1 (de) 2019-05-21 2025-10-22 Ardelyx, Inc. Kombination zur senkung des serum-phosphatspiegels bei einem patienten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them
US3538104A (en) * 1969-02-28 1970-11-03 Geigy Chem Corp Pyridyl-2-imidazolones
ZA803332B (en) * 1979-06-18 1981-01-28 Richardson Merrell Inc Novel 4-aroylimidazol-2-ones
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones

Also Published As

Publication number Publication date
KR830009046A (ko) 1983-12-17
IL65137A (en) 1987-02-27
IL65137A0 (en) 1982-05-31
AU557590B2 (en) 1986-12-24
GB2096600A (en) 1982-10-20
ES510087A0 (es) 1983-04-16
ES8305352A1 (es) 1983-04-16
HK61686A (en) 1986-08-29
DK168627B1 (da) 1994-05-09
DK95482A (da) 1982-09-06
NO157175C (no) 1988-02-03
AU8103782A (en) 1982-09-09
GB2096600B (en) 1985-06-05
US4405628A (en) 1983-09-20
EP0059948A1 (de) 1982-09-15
NO157175B (no) 1987-10-26
ATE16489T1 (de) 1985-11-15
CA1190550A (en) 1985-07-16
DE3267352D1 (en) 1985-12-19
NZ199885A (en) 1985-04-30
KR890000765B1 (ko) 1989-04-05
EP0059948B1 (de) 1985-11-13
ES519254A0 (es) 1984-03-01
GR76518B (de) 1984-08-10
IE52387B1 (en) 1987-10-14
PH18345A (en) 1985-06-05
ES8402827A1 (es) 1984-03-01
NO820686L (no) 1982-09-06
IE820491L (en) 1982-09-05

Similar Documents

Publication Publication Date Title
GB2096600B (en) Aroylimidazolones and analogues thereof
EP0179808A4 (de) Arzneimittelzusammensetzung geeignet zur behandlung oder prophylaxe von herzstörungen.
ATE7387T1 (de) Herstellung des calciumsalzes von alpha-hydroxy- gamma-methylmercaptobuttersaeure.
JPS57122085A (en) Circulatory disease extirpenter and use
IE822519L (en) Phosphonic acid derivatives
DE3778587D1 (de) Herzschrittmacher zur stimulierung des menschlichen herzens.
IL65588A0 (en) Pharmaceutical compositions for the treatment of skin
NO864514D0 (no) Fremgangsmaate for fremstilling av thiazoloner.
ES546090A0 (es) Proceso para preparar tejido implantable para retardar la mineralizacion.
DE3462688D1 (en) 1,7-diphenyl-3-methylaza-7-cyano-8-methylnonane useful in combating diseases
DE3686472D1 (de) Cardiotonische phenyloxazolone.
IT1221010B (it) Impiego di chinoloni nel trattamento di malattie cardiache
ES8504182A1 (es) Procedimiento para preparar nuevos derivados de piperidina
GR75239B (de)
ZA873928B (en) Topical methotrexate preparation for the treatment of hyperproliferative epithelial disease
GR77250B (de)
PH25506A (en) Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants
DE3564763D1 (en) Appliance for the lung treatment of man or animal
FR2474863B1 (de)
ES530605A0 (es) Procedimiento para fabricar compuestos piperidinonicos eficaces en el tratamiento de cardiopatias
GB2120079B (en) Improvements in or relating to the manufacture of footwear
IT1212555B (it) Composizione a base di dobesilato di calcio per il trattamento di malattie cardiache
IT8322047A0 (it) Composizione per la stimolazione della tricogenesi.