NL174144C - 6,7-dialkoxy-4-piperidinochinazolinen, alsmede werkwijze ter bereiding van dergelijke verbindingen en farmaceutische preparaten, die deze verbindingen bevatten. - Google Patents
6,7-dialkoxy-4-piperidinochinazolinen, alsmede werkwijze ter bereiding van dergelijke verbindingen en farmaceutische preparaten, die deze verbindingen bevatten.Info
- Publication number
- NL174144C NL174144C NLAANVRAGE7810865,A NL7810865A NL174144C NL 174144 C NL174144 C NL 174144C NL 7810865 A NL7810865 A NL 7810865A NL 174144 C NL174144 C NL 174144C
- Authority
- NL
- Netherlands
- Prior art keywords
- compounds
- piperidinoquinazolines
- dialkoxy
- preparing
- pharmaceutical preparations
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4566977 | 1977-11-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL7810865A NL7810865A (nl) | 1979-05-07 |
| NL174144B NL174144B (nl) | 1983-12-01 |
| NL174144C true NL174144C (nl) | 1984-05-01 |
Family
ID=10438111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7810865,A NL174144C (nl) | 1977-11-03 | 1978-11-01 | 6,7-dialkoxy-4-piperidinochinazolinen, alsmede werkwijze ter bereiding van dergelijke verbindingen en farmaceutische preparaten, die deze verbindingen bevatten. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4188391A (fr) |
| JP (1) | JPS5498786A (fr) |
| AR (2) | AR221851A1 (fr) |
| AT (1) | AT366043B (fr) |
| AU (1) | AU506317B2 (fr) |
| BE (1) | BE871769A (fr) |
| CA (1) | CA1086735A (fr) |
| CH (1) | CH637130A5 (fr) |
| DE (1) | DE2847622A1 (fr) |
| DK (1) | DK488078A (fr) |
| ES (2) | ES474763A1 (fr) |
| FI (1) | FI63934C (fr) |
| FR (1) | FR2407926A1 (fr) |
| HK (1) | HK94184A (fr) |
| IE (1) | IE47996B1 (fr) |
| IL (1) | IL55845A (fr) |
| IT (1) | IT1101287B (fr) |
| KE (1) | KE3351A (fr) |
| LU (1) | LU80461A1 (fr) |
| MY (1) | MY8500284A (fr) |
| NL (1) | NL174144C (fr) |
| PH (1) | PH14693A (fr) |
| PT (1) | PT68733A (fr) |
| SE (1) | SE7811323L (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4489075A (en) * | 1982-05-15 | 1984-12-18 | Pfizer Inc. | Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants |
| JPS61215389A (ja) * | 1985-03-20 | 1986-09-25 | Kyowa Hakko Kogyo Co Ltd | キナゾリン誘導体およびそれを含有する強心剤 |
| EP0669324A4 (fr) * | 1993-09-10 | 1996-04-03 | Eisai Co Ltd | Compose de quinazoline. |
| CA2262569A1 (fr) | 1996-08-09 | 1998-02-19 | Norihito Ohi | Derives de benzopiperidine |
| EP2275096A3 (fr) | 2005-08-26 | 2011-07-13 | Braincells, Inc. | Neurogenese par modulation des recepteurs muscariniques |
| EP2258357A3 (fr) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenèse avec inhibiteur de l'acetylcholinestérase |
| WO2007047978A2 (fr) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation de la neurogenese par inhibition de la pde |
| EP2314289A1 (fr) | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Modulation de la neurogenese dont la médiation est assurée par récepteur gaba |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| CA2643199A1 (fr) * | 2006-03-08 | 2007-09-13 | Braincells, Inc. | Modulation de neurogenese par des agents nootropes |
| US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| EP2021000A2 (fr) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenèse par modulation de l'angiotensine |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| WO2008030651A1 (fr) * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinaisons contenant un dérivé de 4-acylaminopyridine |
| EP2066355A2 (fr) * | 2006-09-19 | 2009-06-10 | Braincells, Inc. | Combinaison comprenant un agent ppar et un deuxième agent neurogène pour le traitement d'une maladie du système nerveux central, pour augmenter la différentiation neuronale et pour augmenter la neurogenèse |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| CA2663044C (fr) * | 2006-10-06 | 2012-07-24 | Bausch & Lomb Incorporated | Acides quinolone-carboxyliques, derives de ceux-ci et methodes pour les produire et les utiliser |
| US7632944B2 (en) * | 2007-01-24 | 2009-12-15 | Bausch & Lomb Incorporated | Quinolone carboxylic acids, derivatives thereof, and methods of making and using same |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2013106547A1 (fr) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation |
| WO2020190912A1 (fr) | 2019-03-19 | 2020-09-24 | Stingray Therapeutics, Inc. | Composés de quinoléine et de quinazoline et leurs procédés d'utilisation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3812127A (en) * | 1966-10-31 | 1974-05-21 | Pfizer | 4-(quinolin-4-yl)piperazine-1-carboxylic acid esters |
| GB1199768A (en) * | 1966-10-31 | 1970-07-22 | Pfizer & Co C | Nitrogen Heterocycles and process for their preparation |
| US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
| GB1460389A (en) * | 1974-07-25 | 1977-01-06 | Pfizer Ltd | 4-substituted quinazoline cardiac stimulants |
-
1978
- 1978-10-24 CA CA314,062A patent/CA1086735A/fr not_active Expired
- 1978-10-26 US US05/954,931 patent/US4188391A/en not_active Expired - Lifetime
- 1978-10-30 PH PH21751A patent/PH14693A/en unknown
- 1978-10-31 LU LU80461A patent/LU80461A1/fr unknown
- 1978-11-01 IL IL55845A patent/IL55845A/xx unknown
- 1978-11-01 SE SE7811323A patent/SE7811323L/xx unknown
- 1978-11-01 AR AR274310A patent/AR221851A1/es active
- 1978-11-01 CH CH1125378A patent/CH637130A5/de not_active IP Right Cessation
- 1978-11-01 NL NLAANVRAGE7810865,A patent/NL174144C/xx not_active IP Right Cessation
- 1978-11-01 FI FI783325A patent/FI63934C/fi not_active IP Right Cessation
- 1978-11-01 DK DK488078A patent/DK488078A/da not_active Application Discontinuation
- 1978-11-02 AU AU41277/78A patent/AU506317B2/en not_active Expired
- 1978-11-02 AT AT0783878A patent/AT366043B/de not_active IP Right Cessation
- 1978-11-02 ES ES474763A patent/ES474763A1/es not_active Expired
- 1978-11-02 JP JP13569678A patent/JPS5498786A/ja active Granted
- 1978-11-02 DE DE19782847622 patent/DE2847622A1/de not_active Ceased
- 1978-11-02 IT IT29368/78A patent/IT1101287B/it active
- 1978-11-02 IE IE2165/78A patent/IE47996B1/en unknown
- 1978-11-02 PT PT68733A patent/PT68733A/pt unknown
- 1978-11-02 FR FR7831062A patent/FR2407926A1/fr active Granted
- 1978-11-03 BE BE191542A patent/BE871769A/fr not_active IP Right Cessation
-
1979
- 1979-04-27 ES ES480053A patent/ES480053A1/es not_active Expired
- 1979-11-01 AR AR278733A patent/AR221251A1/es active
-
1983
- 1983-11-21 KE KE3351A patent/KE3351A/xx unknown
-
1984
- 1984-11-29 HK HK941/84A patent/HK94184A/xx unknown
-
1985
- 1985-12-30 MY MY284/85A patent/MY8500284A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4127778A (en) | 1979-05-17 |
| AU506317B2 (en) | 1979-12-20 |
| NL174144B (nl) | 1983-12-01 |
| AT366043B (de) | 1982-03-10 |
| IT7829368A0 (it) | 1978-11-02 |
| US4188391A (en) | 1980-02-12 |
| DE2847622A1 (de) | 1979-05-31 |
| FI63934C (fi) | 1983-09-12 |
| SE7811323L (sv) | 1979-05-04 |
| NL7810865A (nl) | 1979-05-07 |
| DK488078A (da) | 1979-05-04 |
| JPS566428B2 (fr) | 1981-02-10 |
| PT68733A (en) | 1978-12-01 |
| IL55845A (en) | 1982-07-30 |
| ES474763A1 (es) | 1980-12-16 |
| ATA783878A (de) | 1981-07-15 |
| FR2407926B1 (fr) | 1982-11-12 |
| CH637130A5 (de) | 1983-07-15 |
| IT1101287B (it) | 1985-09-28 |
| IL55845A0 (en) | 1979-01-31 |
| IE47996B1 (en) | 1984-08-22 |
| AR221851A1 (es) | 1981-03-31 |
| HK94184A (en) | 1984-12-07 |
| CA1086735A (fr) | 1980-09-30 |
| FI63934B (fi) | 1983-05-31 |
| FI783325A7 (fi) | 1979-05-04 |
| ES480053A1 (es) | 1980-07-16 |
| FR2407926A1 (fr) | 1979-06-01 |
| AR221251A1 (es) | 1981-01-15 |
| PH14693A (en) | 1981-11-10 |
| BE871769A (fr) | 1979-05-03 |
| JPS5498786A (en) | 1979-08-03 |
| KE3351A (en) | 1983-12-16 |
| LU80461A1 (fr) | 1980-05-07 |
| MY8500284A (en) | 1985-12-31 |
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| A1A | A request for search or an international-type search has been filed | ||
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| V1 | Lapsed because of non-payment of the annual fee |