NL178421C - Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat. - Google Patents

Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat.

Info

Publication number
NL178421C
NL178421C NLAANVRAGE7904337,A NL7904337A NL178421C NL 178421 C NL178421 C NL 178421C NL 7904337 A NL7904337 A NL 7904337A NL 178421 C NL178421 C NL 178421C
Authority
NL
Netherlands
Prior art keywords
aminothiazole derivative
sponsulating
immune
inflammatory
effect
Prior art date
Application number
NLAANVRAGE7904337,A
Other languages
English (en)
Dutch (nl)
Other versions
NL178421B (nl
NL7904337A (nl
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7904337A publication Critical patent/NL7904337A/xx
Publication of NL178421B publication Critical patent/NL178421B/xx
Application granted granted Critical
Publication of NL178421C publication Critical patent/NL178421C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B15/00—Nails; Staples
    • F16B15/0023—Nail plates
    • F16B2015/0076—Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7904337,A 1978-06-02 1979-06-01 Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat. NL178421C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91183078A 1978-06-02 1978-06-02

Publications (3)

Publication Number Publication Date
NL7904337A NL7904337A (nl) 1979-12-04
NL178421B NL178421B (nl) 1985-10-16
NL178421C true NL178421C (nl) 1986-03-17

Family

ID=25430923

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7904337,A NL178421C (nl) 1978-06-02 1979-06-01 Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat.

Country Status (36)

Country Link
JP (1) JPS5936988B2 (da)
AR (1) AR226285A1 (da)
AT (1) AT373248B (da)
AU (1) AU511242B2 (da)
BE (1) BE876732A (da)
CA (1) CA1117949A (da)
CH (1) CH639653A5 (da)
CS (1) CS216927B2 (da)
DD (1) DD144055A5 (da)
DE (1) DE2922523C2 (da)
DK (1) DK150068C (da)
EG (1) EG14354A (da)
ES (1) ES481220A1 (da)
FI (1) FI68820C (da)
FR (1) FR2427333A1 (da)
GB (1) GB2022085B (da)
GR (1) GR73142B (da)
HK (1) HK66487A (da)
HU (1) HU180045B (da)
IE (1) IE48426B1 (da)
IL (1) IL57450A (da)
IT (1) IT1121238B (da)
KE (1) KE3459A (da)
LU (1) LU81349A1 (da)
MY (1) MY8500318A (da)
NL (1) NL178421C (da)
NO (1) NO150760C (da)
NZ (1) NZ190623A (da)
PH (1) PH17020A (da)
PL (1) PL117515B1 (da)
PT (1) PT69718A (da)
SE (1) SE438333B (da)
SG (1) SG56184G (da)
SU (1) SU843746A3 (da)
YU (1) YU40997B (da)
ZA (1) ZA792729B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001481A1 (en) * 1980-10-24 1982-05-13 Ronald P Hansen Dust mitigation system
US4511574A (en) * 1981-01-08 1985-04-16 Mitsui Toatsu Kagaku Kabushiki Kaisha N-(4-Phenyl-2-thiazolyl)carbamate derivatives
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
WO1982002386A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
WO1982002383A1 (fr) * 1981-01-13 1982-07-22 Sakano Isao Nouveaux composes de thiazol, procede de preparation, et composition medicinale en contenant
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (de) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen
WO1986003203A1 (fr) * 1984-11-22 1986-06-05 Yoshitomi Pharmaceutical Industries, Ltd. Derives de thienylthiazole
FR2581063B1 (fr) * 1985-04-30 1987-07-17 Chauvin Blache Lab Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS63152368A (ja) * 1986-06-03 1988-06-24 Sumitomo Pharmaceut Co Ltd 新規なアミノアゾ−ル誘導体およびその酸付加塩
JPH075579B2 (ja) * 1986-09-01 1995-01-25 吉富製薬株式会社 アミノチアゾ−ル化合物
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
ES2111540T3 (es) * 1989-08-10 1998-03-16 Commw Scient Ind Res Org Metodo para la produccion de una electrosuspension de microparticulas.
AU654125B2 (en) * 1991-03-07 1994-10-27 Hisamitsu Pharmaceutical Co., Inc. Novel diphenylthyazole derivative
FR2692893B1 (fr) * 1992-06-24 1994-09-02 Sanofi Elf Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
WO1996003392A1 (en) * 1994-07-27 1996-02-08 G.D. Searle & Co. Substituted thiazoles for the treatment of inflammation
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
ATE414079T1 (de) 2000-03-01 2008-11-15 Janssen Pharmaceutica Nv 2,4-disubstituierte thiazolyl derivate
EP1423113A4 (en) * 2001-08-13 2007-04-18 Phenex Pharmaceuticals Ag NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS
WO2003027094A2 (en) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors
RU2330839C2 (ru) 2002-01-11 2008-08-10 Санкио Компани, Лимитед Производные аминоспиртов или производные фосфорных кислот и фармацевтические композиции, содержащие указанные производные
EP1555264A1 (en) * 2004-01-15 2005-07-20 Sireen AG Five-membered heterocyclic compounds as inhibitors of SRC family protein kinase.
TWI355934B (en) 2004-02-24 2012-01-11 Sankyo Co Pharmaceutical composition for treatment or prophy
SG159561A1 (en) 2005-05-09 2010-03-30 Achillion Pharmaceuticals Inc Thiazole compounds and methods of use
CN101421265A (zh) 2006-01-18 2009-04-29 安姆根有限公司 作为蛋白激酶b(pkb)抑制剂的噻唑化合物
AU2008276521B2 (en) 2007-07-17 2011-11-03 Amgen Inc. Heterocyclic modulators of PKB
WO2009011871A2 (en) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
US20130143927A1 (en) * 2011-06-10 2013-06-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
US20120316182A1 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
US9856240B2 (en) 2011-10-19 2018-01-02 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN110590785B (zh) * 2019-09-23 2021-02-02 武汉大学 一种氨基噻唑类化合物及其制备方法与抗肠道病毒71型的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458526A (en) * 1966-09-26 1969-07-29 Upjohn Co Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

Also Published As

Publication number Publication date
BE876732A (fr) 1979-12-03
DE2922523C2 (de) 1982-10-21
DD144055A5 (de) 1980-09-24
KE3459A (en) 1984-10-12
JPS54160369A (en) 1979-12-19
FR2427333A1 (fr) 1979-12-28
EG14354A (en) 1984-06-30
GB2022085B (en) 1983-01-12
AT373248B (de) 1983-12-27
DK150068B (da) 1986-12-01
GR73142B (da) 1984-02-09
PL117515B1 (en) 1981-08-31
PT69718A (en) 1979-07-01
CH639653A5 (fr) 1983-11-30
CS216927B2 (en) 1982-12-31
IL57450A0 (en) 1979-09-30
NL178421B (nl) 1985-10-16
NO150760B (no) 1984-09-03
MY8500318A (en) 1985-12-31
FI791754A7 (fi) 1979-11-26
NL7904337A (nl) 1979-12-04
YU40997B (en) 1986-10-31
AU511242B2 (en) 1980-08-07
FR2427333B1 (da) 1983-05-20
SU843746A3 (ru) 1981-06-30
FI68820B (fi) 1985-07-31
JPS5936988B2 (ja) 1984-09-06
SE7904798L (sv) 1979-12-03
AU4763479A (en) 1979-12-06
IT7923228A0 (it) 1979-06-01
NO791831L (no) 1979-12-04
ATA401679A (de) 1983-05-15
SE438333B (sv) 1985-04-15
IL57450A (en) 1982-11-30
DK150068C (da) 1987-06-29
IT1121238B (it) 1986-03-26
DK177679A (da) 1979-12-03
HK66487A (en) 1987-09-25
CA1117949A (en) 1982-02-09
FI68820C (fi) 1985-11-11
DE2922523A1 (de) 1979-12-06
LU81349A1 (fr) 1979-12-07
ZA792729B (en) 1981-03-25
GB2022085A (en) 1979-12-12
IE48426B1 (en) 1985-01-23
IE791069L (en) 1979-12-02
AR226285A1 (es) 1982-06-30
ES481220A1 (es) 1980-09-01
NO150760C (no) 1984-12-12
NZ190623A (en) 1984-07-06
HU180045B (en) 1983-01-28
PL216030A1 (da) 1980-03-10
YU128879A (en) 1982-10-31
PH17020A (en) 1984-05-11
SG56184G (en) 1985-03-08

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Legal Events

Date Code Title Description
A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee