NL7614308A - Werkwijze voor de bereiding van esterderivaten van fenylazijnzuur en de toepassing hiervan als geneesmiddel. - Google Patents
Werkwijze voor de bereiding van esterderivaten van fenylazijnzuur en de toepassing hiervan als geneesmiddel.Info
- Publication number
- NL7614308A NL7614308A NL7614308A NL7614308A NL7614308A NL 7614308 A NL7614308 A NL 7614308A NL 7614308 A NL7614308 A NL 7614308A NL 7614308 A NL7614308 A NL 7614308A NL 7614308 A NL7614308 A NL 7614308A
- Authority
- NL
- Netherlands
- Prior art keywords
- phenylaic
- preparation
- acid
- ester derivatives
- medicinal product
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50156799A JPS5826744B2 (ja) | 1975-12-24 | 1975-12-24 | シンキナプロピオンサン エステルユウドウタイノセイゾウホウ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL7614308A true NL7614308A (nl) | 1977-06-28 |
| NL180381B NL180381B (nl) | 1986-09-16 |
| NL180381C NL180381C (nl) | 1987-02-16 |
Family
ID=15635562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7614308,A NL180381C (nl) | 1975-12-24 | 1976-12-23 | Werkwijze ter bereiding van een 2-(4-isobutylfenyl)propionzure ester bevattend geneesmiddel en werkwijze ter bereiding van de geneeskrachtige verbindingen. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5826744B2 (nl) |
| AU (1) | AU507661B2 (nl) |
| CA (1) | CA1076134A (nl) |
| CH (1) | CH617919A5 (nl) |
| DE (1) | DE2658610C2 (nl) |
| FR (1) | FR2336126A1 (nl) |
| GB (1) | GB1573322A (nl) |
| NL (1) | NL180381C (nl) |
| SE (1) | SE433492B (nl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54144336A (en) * | 1978-07-24 | 1979-11-10 | Teikoku Seiyaku Kk | Propionic acid propylester derivative*its manufacture and antiiinflammatory and sedative agent containing it |
| JPS5517358A (en) * | 1978-07-24 | 1980-02-06 | Teikoku Seiyaku Kk | Butyl propionate derivative, its preparation, and antiphlogistic and analgesic comprising it |
| JPS5587770A (en) * | 1978-12-27 | 1980-07-02 | Hisamitsu Pharmaceut Co Inc | Preparation of 2-(p-isobutylphenyl)propionic acid 2-pyridinemethyl ester |
| JPS57203035A (en) * | 1981-06-05 | 1982-12-13 | Taisho Pharmaceut Co Ltd | Carboxylic acid ester |
| DE3225290A1 (de) * | 1982-07-07 | 1984-01-12 | Merck Patent Gmbh | Ringverbindungen |
| YU43408B (en) * | 1985-04-26 | 1989-06-30 | Lek Tovarna Farmacevtskih | Process for preparation of 2-(4-isobuthylphenyl)-prophiohydroxamic acid |
| JPH0635378B2 (ja) * | 1985-06-27 | 1994-05-11 | ポ−ラ化成工業株式会社 | 化粧料 |
| ES2004447A6 (es) * | 1987-07-06 | 1989-01-01 | Sune Coma Nuria | Procedimiento de obtencion de un nuevo ester del acido 2-(p-isobutilfeni)-propionico |
| DE3811118C1 (nl) * | 1988-03-31 | 1989-10-12 | Merckle Gmbh, 7902 Blaubeuren, De | |
| IT1217589B (it) * | 1988-05-13 | 1990-03-30 | Pulitzer Italiana | Agente antiinfiammatorio per la terapia dell'ipertrofia prostatica,sua preparazione e relative composizioni farmaceutiche |
| JPH0639449B2 (ja) * | 1989-04-10 | 1994-05-25 | エーザイ株式会社 | ポリプレニル系化合物およびその製造方法ならびにそれを含有する医薬 |
| UA34430C2 (uk) | 1991-05-13 | 2001-03-15 | Дзе Бутс Компані Плс | S(-)-2-(4-ізобутилфеніл)пропіонат натрію дигідрат, придатний для лікування запалення, болю і гіпертермії, фармацевтична композиція на його основі та спосіб одержання s(-)-2-(4-ізобутилфеніл)пропіонату натрію |
| US6399618B1 (en) * | 1997-07-09 | 2002-06-04 | Cardiome Pharma Corp | Compositions and methods for modulating sexual activity |
| CN103948571A (zh) * | 2006-07-18 | 2014-07-30 | 天津昕晨泰飞尔医药科技有限公司 | 具有快速皮肤穿透率的带正电荷的水溶性布洛芬前药 |
| JP5424880B2 (ja) * | 2006-08-15 | 2014-02-26 | テックフィールズ バイオケム カンパニー リミテッド | 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ |
| KR20150058566A (ko) | 2007-06-04 | 2015-05-28 | 테크필즈 인크 | 매우 높은 피부 및 막 침투율을 가지는 ｎｓａｉａ 약물전구체 및 이들의 새로운 의약적 용도 |
| EP2773378B1 (en) | 2011-10-31 | 2016-08-10 | Larsen, Claus Selch | Prodrugs of non-steroid anti-inflammatory agents (nsaids) |
| US9557087B2 (en) | 2012-12-13 | 2017-01-31 | Whirlpool Corporation | Clear ice making apparatus having an oscillation frequency and angle |
| US9470448B2 (en) | 2012-12-13 | 2016-10-18 | Whirlpool Corporation | Apparatus to warm plastic side of mold |
| US9759472B2 (en) | 2012-12-13 | 2017-09-12 | Whirlpool Corporation | Clear ice maker with warm air flow |
| US9500398B2 (en) | 2012-12-13 | 2016-11-22 | Whirlpool Corporation | Twist harvest ice geometry |
| CN105461731B (zh) * | 2014-08-07 | 2017-05-24 | 富力 | 连翘脂素布洛芬酯、其制备及其应用 |
| WO2016065269A2 (en) | 2014-10-23 | 2016-04-28 | Whirlpool Corporation | Method and apparatus for increasing rate of ice production in an automatic ice maker |
| JP6153264B2 (ja) * | 2015-01-05 | 2017-06-28 | テックフィールズ インコーポレイテッド | 非常に速い皮膚及び膜浸透速度を有するｎｓａｉａプロドラッグ及びその新規医薬使用 |
| CN109134262A (zh) * | 2017-06-15 | 2019-01-04 | 北京蓝丹医药科技有限公司 | 一种洛索洛芬衍生物 |
| CN109134261A (zh) * | 2017-06-15 | 2019-01-04 | 北京蓝丹医药科技有限公司 | 一种洛索洛芬衍生物 |
| US10907874B2 (en) | 2018-10-22 | 2021-02-02 | Whirlpool Corporation | Ice maker downspout |
| CA3199426A1 (en) * | 2020-06-05 | 2021-12-09 | Chongxi Yu | Topical administration of 2-(diethylamino)ethyl 2-(4-isobutylphenyl)propionate for treatment of diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
-
1975
- 1975-12-24 JP JP50156799A patent/JPS5826744B2/ja not_active Expired
-
1976
- 1976-12-06 SE SE7613651A patent/SE433492B/xx not_active IP Right Cessation
- 1976-12-13 CA CA267,690A patent/CA1076134A/en not_active Expired
- 1976-12-21 CH CH1607276A patent/CH617919A5/fr not_active IP Right Cessation
- 1976-12-21 FR FR7638482A patent/FR2336126A1/fr active Granted
- 1976-12-23 NL NLAANVRAGE7614308,A patent/NL180381C/nl not_active IP Right Cessation
- 1976-12-23 DE DE2658610A patent/DE2658610C2/de not_active Expired
- 1976-12-23 AU AU20878/76A patent/AU507661B2/en not_active Expired
- 1976-12-24 GB GB51350/76A patent/GB1573322A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU507661B2 (en) | 1980-02-21 |
| JPS5826744B2 (ja) | 1983-06-04 |
| DE2658610C2 (de) | 1982-12-23 |
| CA1076134A (en) | 1980-04-22 |
| NL180381C (nl) | 1987-02-16 |
| DE2658610A1 (de) | 1977-07-07 |
| FR2336126A1 (fr) | 1977-07-22 |
| SE433492B (sv) | 1984-05-28 |
| GB1573322A (en) | 1980-08-20 |
| SE7613651L (sv) | 1977-06-25 |
| CH617919A5 (en) | 1980-06-30 |
| AU2087876A (en) | 1978-06-29 |
| JPS5278848A (en) | 1977-07-02 |
| NL180381B (nl) | 1986-09-16 |
| FR2336126B1 (nl) | 1979-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| SNR | Assignments of patents or rights arising from examined patent applications |
Owner name: AB NYNAES PETROLEUM |
|
| V4 | Lapsed because of reaching the maximum lifetime of a patent |
Free format text: 961223 |