NL7711273A - Werkwijze ter bereiding van maytansinol en de- rivaten daarvan. - Google Patents

Werkwijze ter bereiding van maytansinol en de- rivaten daarvan.

Info

Publication number: NL7711273A
Authority: NL; Netherlands
Prior art keywords: maytansinol; preparation; devices
Prior art date: 1977-03-31

Application number

NL7711273A

Other languages

English (en)

Dutch (nl)

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-03-31

Filing date

1977-10-13

Publication date

1978-10-03

1977-10-13 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1978-10-03 Publication of NL7711273A publication Critical patent/NL7711273A/xx

Links

QWPXBEHQFHACTK-RZKXNLMUSA-N CO[C@@H]([C@@]1(O)C[C@H](OC(=O)N1)[C@@H](C)[C@@H]1O[C@@]1(C)[C@@H](O)CC(=O)N1C)\C=C\C=C(C)\CC2=CC(OC)=C(Cl)C1=C2 Chemical compound CO[C@@H]([C@@]1(O)C[C@H](OC(=O)N1)[C@@H](C)[C@@H]1O[C@@]1(C)[C@@H](O)CC(=O)N1C)\C=C\C=C(C)\CC2=CC(OC)=C(Cl)C1=C2 QWPXBEHQFHACTK-RZKXNLMUSA-N 0.000 title 1
QWPXBEHQFHACTK-UHFFFAOYSA-N Maytansinol Natural products CN1C(=O)CC(O)C2(C)OC2C(C)C(OC(=O)N2)CC2(O)C(OC)C=CC=C(C)CC2=CC(OC)=C(Cl)C1=C2 QWPXBEHQFHACTK-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Public Health (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)

NL7711273A 1977-03-31 1977-10-13 Werkwijze ter bereiding van maytansinol en de- rivaten daarvan. NL7711273A (nl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP52037167A JPS6010718B2 (ja)	1977-03-31	1977-03-31	メイタンシノ−ル，メイタナシンおよびメイタンシノ−ル・プロピオネ−トの製造法

Publications (1)

Publication Number	Publication Date
NL7711273A true NL7711273A (nl)	1978-10-03

Family

ID=12490032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL7711273A NL7711273A (nl)	1977-03-31	1977-10-13	Werkwijze ter bereiding van maytansinol en de- rivaten daarvan.

Country Status (20)

Country	Link
JP (1)	JPS6010718B2 (pl)
AT (1)	AT362058B (pl)
AU (1)	AU507869B2 (pl)
CA (1)	CA1092999A (pl)
CH (1)	CH631740A5 (pl)
CS (1)	CS214881B2 (pl)
DE (1)	DE2746253C2 (pl)
DK (1)	DK143570C (pl)
ES (1)	ES463206A1 (pl)
FR (1)	FR2385798A1 (pl)
GB (1)	GB1554395A (pl)
HU (1)	HU177391B (pl)
IE (1)	IE45888B1 (pl)
IT (1)	IT1094003B (pl)
NL (1)	NL7711273A (pl)
PL (1)	PL108863B1 (pl)
PT (1)	PT67853B (pl)
SE (1)	SE7711543L (pl)
SU (1)	SU938746A3 (pl)
YU (1)	YU243777A (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6010720B2 (ja) *	1977-11-18	1985-03-19	武田薬品工業株式会社	抗生物質ｃ―１５００３ｐ―４の製造法
JPS6016236B2 (ja) *	1977-11-18	1985-04-24	武田薬品工業株式会社	抗生物質ｃ―１５００３ｐ―３の製造法
JPS55162791A (en) *	1979-06-05	1980-12-18	Takeda Chem Ind Ltd	Antibiotic c-15003pnd and its preparation
EP0028683A1 (en) *	1979-09-21	1981-05-20	Takeda Chemical Industries, Ltd.	Antibiotic C-15003 PHO and production thereof
US6573074B2 (en)	2000-04-12	2003-06-03	Smithkline Beecham Plc	Methods for ansamitocin production
US6333410B1 (en)	2000-08-18	2001-12-25	Immunogen, Inc.	Process for the preparation and purification of thiol-containing maytansinoids
US7432088B2 (en)	2003-05-08	2008-10-07	Immunogen Inc.	Methods for the production of ansamitocins
CN116239607B (zh) *	2023-01-04	2024-04-09	山东大学	一种美登素衍生物及其生物合成方法与应用

1977
- 1977-03-31 JP JP52037167A patent/JPS6010718B2/ja not_active Expired
- 1977-09-23 AU AU29073/77A patent/AU507869B2/en not_active Expired
- 1977-10-07 FR FR7730340A patent/FR2385798A1/fr active Granted
- 1977-10-07 SU SU772533351A patent/SU938746A3/ru active
- 1977-10-10 YU YU02437/77A patent/YU243777A/xx unknown
- 1977-10-13 SE SE7711543A patent/SE7711543L/ not_active Application Discontinuation
- 1977-10-13 NL NL7711273A patent/NL7711273A/xx not_active Application Discontinuation
- 1977-10-13 CS CS776677A patent/CS214881B2/cs unknown
- 1977-10-13 HU HU77TA1458A patent/HU177391B/hu unknown
- 1977-10-14 CH CH1260477A patent/CH631740A5/de not_active IP Right Cessation
- 1977-10-14 AT AT736377A patent/AT362058B/de not_active IP Right Cessation
- 1977-10-14 CA CA288,732A patent/CA1092999A/en not_active Expired
- 1977-10-14 ES ES463206A patent/ES463206A1/es not_active Expired
- 1977-10-14 DE DE2746253A patent/DE2746253C2/de not_active Expired
- 1977-10-14 GB GB42821/77A patent/GB1554395A/en not_active Expired
- 1977-10-14 DK DK458977A patent/DK143570C/da not_active IP Right Cessation
- 1977-10-14 IE IE2100/77A patent/IE45888B1/en unknown
- 1977-10-15 PL PL1977201539A patent/PL108863B1/pl not_active IP Right Cessation
1978
- 1978-03-30 PT PT67853A patent/PT67853B/pt unknown
- 1978-03-30 IT IT21819/78A patent/IT1094003B/it active

Also Published As

Publication number	Publication date
FR2385798B1 (pl)	1980-04-25
IT7821819A0 (it)	1978-03-30
DK458977A (da)	1978-10-01
HU177391B (en)	1981-09-28
AU2907377A (en)	1979-03-29
DE2746253A1 (de)	1978-10-05
IE45888L (en)	1978-09-30
PL201539A1 (pl)	1978-09-25
PT67853A (en)	1978-04-01
YU243777A (en)	1982-06-30
FR2385798A1 (fr)	1978-10-27
DE2746253C2 (de)	1986-08-21
CH631740A5 (en)	1982-08-31
ES463206A1 (es)	1978-08-16
IT1094003B (it)	1985-07-26
SU938746A3 (ru)	1982-06-23
SE7711543L (sv)	1978-10-01
CA1092999A (en)	1981-01-06
CS214881B2 (en)	1982-06-25
JPS53121998A (en)	1978-10-24
AU507869B2 (en)	1980-02-28
JPS6010718B2 (ja)	1985-03-19
DK143570C (da)	1982-02-08
GB1554395A (en)	1979-10-17
AT362058B (de)	1981-04-27
IE45888B1 (en)	1982-12-29
ATA736377A (de)	1980-09-15
PT67853B (en)	1980-05-05
PL108863B1 (en)	1980-05-31
DK143570B (da)	1981-09-07

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Legal Events

Date	Code	Title
1984-10-01	BA	A request for search or an international-type search has been filed
1984-10-01	BB	A search report has been drawn up
1985-01-01	A85	Still pending on 85-01-01
1985-02-01	BC	A request for examination has been filed
1990-06-01	BV	The patent application has lapsed