NL7905810A - Werkwijze voor het bereiden van farmaceutisch preparaat op basis van een piperazinederivaat, dat actief is ten aanzien van het centrale zenuwstelsel en een pijnstil- lend middel is, werkwijze ter bereiding van het piperazinederivaat en het aldus bereide farmaceutische preparaat. - Google Patents

Werkwijze voor het bereiden van farmaceutisch preparaat op basis van een piperazinederivaat, dat actief is ten aanzien van het centrale zenuwstelsel en een pijnstil- lend middel is, werkwijze ter bereiding van het piperazinederivaat en het aldus bereide farmaceutische preparaat. Download PDF

Info

Publication number
NL7905810A
NL7905810A NL7905810A NL7905810A NL7905810A NL 7905810 A NL7905810 A NL 7905810A NL 7905810 A NL7905810 A NL 7905810A NL 7905810 A NL7905810 A NL 7905810A NL 7905810 A NL7905810 A NL 7905810A
Authority
NL
Netherlands
Prior art keywords
formula
radical
derivatives
preparing
piperazine derivative
Prior art date
Application number
NL7905810A
Other languages
English (en)
Dutch (nl)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7822672A external-priority patent/FR2432515A1/fr
Priority claimed from FR7833105A external-priority patent/FR2442234A2/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of NL7905810A publication Critical patent/NL7905810A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7905810A 1978-08-01 1979-07-27 Werkwijze voor het bereiden van farmaceutisch preparaat op basis van een piperazinederivaat, dat actief is ten aanzien van het centrale zenuwstelsel en een pijnstil- lend middel is, werkwijze ter bereiding van het piperazinederivaat en het aldus bereide farmaceutische preparaat. NL7905810A (nl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR7822672 1978-08-01
FR7822672A FR2432515A1 (fr) 1978-08-01 1978-08-01 Derives de phenyl-1 piperazine et leur application en therapeutique
FR7833105 1978-11-23
FR7833105A FR2442234A2 (fr) 1978-08-01 1978-11-23 Derives de phenyl-1 piperazine et leur application en therapeutique
FR7916029 1979-06-22
FR7916029A FR2459797A2 (fr) 1978-08-01 1979-06-22 Derives de phenyl-1 piperazine et leur application en therapeutique

Publications (1)

Publication Number Publication Date
NL7905810A true NL7905810A (nl) 1980-02-05

Family

ID=27250847

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7905810A NL7905810A (nl) 1978-08-01 1979-07-27 Werkwijze voor het bereiden van farmaceutisch preparaat op basis van een piperazinederivaat, dat actief is ten aanzien van het centrale zenuwstelsel en een pijnstil- lend middel is, werkwijze ter bereiding van het piperazinederivaat en het aldus bereide farmaceutische preparaat.

Country Status (18)

Country Link
JP (1) JPS5522690A (da)
AU (1) AU4930979A (da)
BE (1) BE877994A (da)
DE (1) DE2930440A1 (da)
DK (1) DK321479A (da)
ES (1) ES483003A1 (da)
FI (1) FI792401A7 (da)
FR (1) FR2459797A2 (da)
GB (1) GB2027703A (da)
GR (1) GR69703B (da)
IL (1) IL57920A0 (da)
IT (1) IT1123497B (da)
LU (1) LU81562A1 (da)
NL (1) NL7905810A (da)
NO (1) NO792502L (da)
NZ (1) NZ191140A (da)
PT (1) PT70007A (da)
SE (1) SE7906507L (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2582288B1 (fr) * 1985-05-21 1987-08-07 Massonnet Henry Poubelle compacteuse perfectionnee
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904724D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
SE9904723D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
MXPA06013941A (es) 2004-06-08 2007-12-10 Neurosearch Sweden Ab Fenilpiperidinas disustituidas, novedosas, como moduladores de la neurotransmision de dopamina y serotonina.
NZ552411A (en) 2004-06-08 2010-04-30 Nsab Af Neurosearch Sweden Ab New disubstituted phenylpiperidines/piperazines as modulators of dopamine neurotransmission
US7851629B2 (en) 2004-06-08 2010-12-14 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
PL1802573T3 (pl) 2004-10-13 2017-03-31 Teva Pharmaceuticals International Gmbh Proces syntezy 4-(3-metanosulfonylofenylo)-1-N-propylopiperydyny
SE529246C2 (sv) 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
MX347209B (es) 2011-12-08 2017-04-19 Teva Pharmaceuticals Int Gmbh La sal de bromhidrato de pridopidina.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH353743A (fr) * 1955-06-29 1961-04-30 Parke Davis & Co Procédé de préparation de pipérazines
US2976290A (en) * 1959-04-24 1961-03-21 Parke Davis & Co Piperazine derivatives and methods for their production
FR2224464A1 (en) * 1973-04-05 1974-10-31 Synthelabo N-Phenyl-N'-beta-hydroxy-ethyl piperazines - as analgesic and anti-inflammatory agents

Also Published As

Publication number Publication date
IT1123497B (it) 1986-04-30
IL57920A0 (en) 1979-11-30
FR2459797A2 (fr) 1981-01-16
JPS5522690A (en) 1980-02-18
LU81562A1 (fr) 1981-03-24
BE877994A (fr) 1980-01-31
DE2930440A1 (de) 1980-02-28
FR2459797B2 (da) 1982-05-14
AU4930979A (en) 1980-02-07
PT70007A (fr) 1979-08-01
DK321479A (da) 1980-02-02
FI792401A7 (fi) 1981-01-01
GB2027703A (en) 1980-02-27
ES483003A1 (es) 1980-04-16
GR69703B (da) 1982-07-09
NZ191140A (en) 1981-01-23
IT7924749A0 (it) 1979-07-27
SE7906507L (sv) 1980-02-02
NO792502L (no) 1980-02-04

Similar Documents

Publication Publication Date Title
US5098903A (en) Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents
CA2057578C (fr) Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
EP2865381A1 (en) ITK inhibitors for treating blood cell malignancies
JP4190030B2 (ja) 抗酸化剤としてのアリールアルキルピペラジン化合物
JPH0214352B2 (da)
EP0541617B1 (en) 1,4-disubstituted piperazines
US5422367A (en) Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents
WO2024026573A1 (en) 3-ethylamino-indole dimers as serotonergic agents useful for the treatment of disorders related thereto
US4267328A (en) 1-Phenylpiperazines
US3573291A (en) Cinnamylpiperazine preparations
GB2027703A (en) 1-Phenylpiperazine derivatives
NL8201509A (nl) Werkwijze ter bereiding van piperazinederivaten, alsmede werkwijze ter vervaardiging van farmaceutica hiermede.
US3929792A (en) Phenylpiperazine derivatives, process for their preparation and applications thereof
DK168861B1 (da) 4-methyl-5-(2-(4-phenyl-1-piperazinyl)ethyl)thiazolderivater og fremgangsmåde til fremstilling deraf, farmaceutiske midler indeholdende thiazolderivaterne og fremgangsmåde til fremstilling deraf og anvendelse af derivaterne til fremstilling af lægemidler
RU2208610C2 (ru) Пиперазиновые производные, способ их получения и содержащая их композиция
US4540696A (en) 1-Piperazinyl 4-phenylquinazoline compounds having antidepressant properties and drugs containing same
BG63917B1 (bg) 1-ар(алк)ил-имидазолин-2-они с дизаместен аминов остатък на 4-място, с антиконвулсивно действие и метод за получаването им
JPS647995B2 (da)
CA1320958C (en) 2-carbonyl substituted n,n'-di-(trimethoxybenzoyl) piperazines, process for preparing the same and therapeutical compounds containing them
NZ226502A (en) Piperazinylmethyl-pyrrolyl (or furanyl)-alkyl piperidin-2-one derivatives and pharmaceutical compositions
RU2069661C1 (ru) Алкилендиаминовые производные или их фармацевтически приемлемые соли
JP3035475B2 (ja) １−（アリールアルケニル）−４−（アリールメチル）ピペラジン構造を有する新規化合物、その製造方法及びそれを含有する薬学的組成物
RU2619110C2 (ru) Производные пиперазина, способы их получения и их применение в лечении инсулинорезистентности
US4242343A (en) Phenylpiperazine derivatives
EP1507523A1 (en) Cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease

Legal Events

Date Code Title Description
BV The patent application has lapsed