NL8301552A - Nieuwe azepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. - Google Patents

Nieuwe azepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. Download PDF

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Publication number
NL8301552A
NL8301552A NL8301552A NL8301552A NL8301552A NL 8301552 A NL8301552 A NL 8301552A NL 8301552 A NL8301552 A NL 8301552A NL 8301552 A NL8301552 A NL 8301552A NL 8301552 A NL8301552 A NL 8301552A
Authority
NL
Netherlands
Prior art keywords
group
acid addition
addition salt
carbon atoms
formula
Prior art date
Application number
NL8301552A
Other languages
English (en)
Dutch (nl)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NL8301552A publication Critical patent/NL8301552A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NL8301552A 1982-05-06 1983-05-03 Nieuwe azepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. NL8301552A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH280682 1982-05-06
CH2806/82A CH649553A5 (de) 1982-05-06 1982-05-06 Azepinoindole und verfahren zu deren herstellung.

Publications (1)

Publication Number Publication Date
NL8301552A true NL8301552A (nl) 1983-12-01

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8301552A NL8301552A (nl) 1982-05-06 1983-05-03 Nieuwe azepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.

Country Status (17)

Country Link
JP (1) JPS58203993A (fr)
AU (1) AU1425683A (fr)
BE (1) BE896590A (fr)
CH (1) CH649553A5 (fr)
DE (1) DE3315467A1 (fr)
DK (1) DK199883A (fr)
ES (1) ES522008A0 (fr)
FI (1) FI831475A7 (fr)
FR (1) FR2526434A1 (fr)
GB (1) GB2120662B (fr)
HU (1) HU189275B (fr)
IL (1) IL68576A0 (fr)
IT (1) IT1197644B (fr)
NL (1) NL8301552A (fr)
PT (1) PT76632B (fr)
SE (1) SE8302554L (fr)
ZA (1) ZA833266B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193083B (en) * 1984-02-22 1987-08-28 Sandoz Ag Process for preparing diazepinoindole derivatives further pharmaceutical compositions containing such compounds
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
JP2004509894A (ja) * 2000-09-20 2004-04-02 ファルマシア・アンド・アップジョン・カンパニー 置換アゼピノ［４，５−ｂ］インドリン誘導体
WO2003014118A1 (fr) * 2001-08-08 2003-02-20 Pharmacia & Upjohn Company 1h-pyrido[4,3-b] indoles therapeutiques
EP1981337B1 (fr) * 2006-01-19 2015-09-02 Athersys, Inc. Azepines de thiophenyle en tant que ligands de recepteurs de serotonine 5-ht2c et leurs utilisations
BRPI0907122B8 (pt) 2008-01-11 2021-05-25 Albany Molecular Res Inc compostos de piridoindóis (1-azinona) substituídos, composição farmacêutica compreendendo os referidos compostos, e usos dos mesmos
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
US8637501B2 (en) 2009-07-01 2014-01-28 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof
WO2011003012A1 (fr) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Antagonistes de mch-1 azapolycycles substitués par azinone, leurs procédés de fabrication et leur utilisation
WO2011003007A1 (fr) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Antagonistes de mch-1 d’azabicycloalcane-indole et d’azabicycloalcane-pyrrolo-pyridine, procédés de préparation, et utilisation de ceux-ci
WO2012088038A2 (fr) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Antagonistes de mch-1 consistant en tétrahydro-carbolines substituées par pipérazinone, leurs procédés de fabrication et utilisations
WO2012088124A2 (fr) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Antagonistes de la mch-1 à base de tétrahydro-azacarboline, leurs procédés de fabrication et leurs utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028381B1 (fr) * 1979-11-02 1985-04-10 Sandoz Ag Azépinoindoles, procédé pour leur préparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
ES8502440A1 (es) 1985-01-01
PT76632B (en) 1986-01-27
JPS58203993A (ja) 1983-11-28
FI831475L (fi) 1983-11-07
PT76632A (en) 1983-06-01
IL68576A0 (en) 1983-09-30
ZA833266B (en) 1984-12-24
CH649553A5 (de) 1985-05-31
GB2120662B (en) 1985-09-11
BE896590A (fr) 1983-10-28
GB2120662A (en) 1983-12-07
IT8348232A0 (it) 1983-05-06
DE3315467A1 (de) 1983-11-17
DK199883D0 (da) 1983-05-04
FI831475A0 (fi) 1983-04-29
FR2526434A1 (fr) 1983-11-10
ES522008A0 (es) 1985-01-01
HU189275B (en) 1986-06-30
IT1197644B (it) 1988-12-06
SE8302554D0 (sv) 1983-05-04
SE8302554L (sv) 1983-11-07
FI831475A7 (fi) 1983-11-07
GB8312159D0 (en) 1983-06-08
DK199883A (da) 1983-11-07
IT8348232A1 (it) 1984-11-06
AU1425683A (en) 1983-11-10

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed