NO139048C - Analogifremgangsmaate for fremstilling av nye analgetisk og/eller antiinflammatorisk virksomme (4h)-5,6-dihydro-(4,3-a)-s-triazolo-1,5-benzodiazepiner - Google Patents

Analogifremgangsmaate for fremstilling av nye analgetisk og/eller antiinflammatorisk virksomme (4h)-5,6-dihydro-(4,3-a)-s-triazolo-1,5-benzodiazepiner

Info

Publication number: NO139048C
Authority: NO; Norway
Prior art keywords: inflammatoric; analgetic; benzodiazepines; triazolo; dihydro
Prior art date: 1973-03-09

Application number

NO740833A

Other languages

English (en)

Norwegian (no)

Other versions

NO139048B (no

NO740833L (no

Inventor

Etienne Szarvasi

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-03-09

Filing date

1974-03-08

Publication date

1979-01-03

1973-03-09 Priority claimed from FR7308510A external-priority patent/FR2220257A1/fr

1973-10-04 Priority claimed from FR7335522A external-priority patent/FR2246273A2/fr

1973-11-22 Priority claimed from FR7341583A external-priority patent/FR2252102A2/fr

1974-03-08 Application filed by Lipha filed Critical Lipha

1974-09-10 Publication of NO740833L publication Critical patent/NO740833L/no

1978-09-18 Publication of NO139048B publication Critical patent/NO139048B/no

1979-01-03 Publication of NO139048C publication Critical patent/NO139048C/no

Links

230000000202 analgesic effect Effects 0.000 title 1
230000003110 anti-inflammatory effect Effects 0.000 title 1
229940049706 benzodiazepine Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO740833A 1973-03-09 1974-03-08 Analogifremgangsmaate for fremstilling av nye analgetisk og/eller antiinflammatorisk virksomme (4h)-5,6-dihydro-(4,3-a)-s-triazolo-1,5-benzodiazepiner NO139048C (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR7308510A FR2220257A1 (en)	1973-03-09	1973-03-09	5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects
FR7335522A FR2246273A2 (en)	1973-10-04	1973-10-04	5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects
FR7341583A FR2252102A2 (en)	1973-11-22	1973-11-22	5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects

Publications (3)

Publication Number	Publication Date
NO740833L NO740833L (no)	1974-09-10
NO139048B NO139048B (no)	1978-09-18
NO139048C true NO139048C (no)	1979-01-03

Family

ID=27250074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO740833A NO139048C (no)	1973-03-09	1974-03-08	Analogifremgangsmaate for fremstilling av nye analgetisk og/eller antiinflammatorisk virksomme (4h)-5,6-dihydro-(4,3-a)-s-triazolo-1,5-benzodiazepiner

Country Status (13)

Country	Link
US (1)	US4110337A (de)
JP (1)	JPS49125395A (de)
CA (1)	CA1011333A (de)
CH (1)	CH589084A5 (de)
DD (1)	DD110497A5 (de)
DE (1)	DE2409308C3 (de)
DK (1)	DK139099B (de)
ES (1)	ES424067A1 (de)
GB (1)	GB1409693A (de)
IE (1)	IE38931B1 (de)
IL (1)	IL44338A (de)
NL (1)	NL7403247A (de)
NO (1)	NO139048C (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
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US4076823A (en) *	1977-08-18	1978-02-28	E. R. Squibb & Sons, Inc.	Triazolo-2,4-benzodiazepines
ES2139595T3 (es) *	1991-04-23	2000-02-16	Toray Industries	Derivados triazolicos triciclicos, fabricacion de los mismos y su utilizacion.
US5683998A (en) *	1991-04-23	1997-11-04	Toray Industries, Inc.	Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
FR2769309B1 (fr)	1997-10-08	2001-06-15	Oreal	Composition de teinture d'oxydation des fibres keratiniques comprenant un derive d'aminoacide en tant que base d'oxydation et nouveaux derives d'aminoacides
US20040176358A1 (en) *	1999-04-30	2004-09-09	The Regents Of The University Of Michigan	Compositions and methods relating to novel compounds and targets thereof
JP5127096B2 (ja)	1999-04-30	2013-01-23	ザリージェンツオブザユニバーシティオブミシガン	アポトーシスにより誘導される自己免疫疾患を処置するためのベンゾジアゼピンの使用
US7144880B2 (en)	1999-04-30	2006-12-05	Regents Of The University Of Michigan	Compositions relating to novel compounds and targets thereof
US7276348B2 (en) *	1999-04-30	2007-10-02	Regents Of The University Of Michigan	Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US20050113460A1 (en) *	1999-04-30	2005-05-26	The Regents Of The University Of Michigan	Compositions and methods relating to novel compounds and targets thereof
US20030119029A1 (en) *	1999-04-30	2003-06-26	Regents Of The University Of Michigan	Compositions and methods relating to novel benzodiazepine compounds and targets thereof
US20060025388A1 (en)	1999-04-30	2006-02-02	Glick Gary D	Compositions and methods relating to novel compounds and targets thereof
US20050272723A1 (en) *	2004-04-27	2005-12-08	The Regents Of The University Of Michigan	Methods and compositions for treating diseases and conditions associated with mitochondrial function
US20060052369A1 (en) *	2004-09-07	2006-03-09	The Regents Of The University Of Michigan	Compositions and methods relating to novel compounds and targets thereof
JP2008528448A (ja) *	2005-01-03	2008-07-31	ザリージェンツオブザユニバーシティオブミシガン	新規化合物に関連する組成物および方法、ならびにその標的
JP2008545757A (ja)	2005-06-01	2008-12-18	ザリージェンツオブザユニバーシティオブミシガン	溶媒和されていないベンゾジアゼピン組成物および方法
US20070105844A1 (en) *	2005-10-26	2007-05-10	Regents Of The University Of Michigan	Therapeutic compositions and methods
EP1948191B1 (de)	2005-11-01	2013-01-16	The Regents of the University of Michigan	Neuartige 1,4-benzodiazepin-2,5-dione mit therapeutischen eigenschaften
DE102005061840A1 (de)	2005-12-23	2007-06-28	Merck Patent Gmbh	Triazolderivate
US7759338B2 (en) *	2006-04-27	2010-07-20	The Regents Of The University Of Michigan	Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2418206A3 (de)	2006-06-09	2012-06-27	The Regents of the University of Michigan	Benzodiazepin-derivate zur behandlung von autoimmunerkrankungen
KR101164718B1 (ko)	2007-03-09	2012-07-11	더 리젠츠 오브 더 유니버시티 오브 미시간	신규 화합물 및 이의 표적에 관한 조성물 및 방법
MX2010002732A (es)	2007-09-14	2010-06-02	Univ Michigan	Inhibidores de f1f0-atpasa y metodos relacionados.
CN101918375A (zh)	2007-11-06	2010-12-15	密歇根大学董事会	在皮肤病症的治疗中有用的苯并二氮杂*酮化合物
US8497307B2 (en)	2008-09-11	2013-07-30	The Regents Of The University Of Michigan	Aryl guanidine F1F0-ATPase inhibitors and related methods
WO2010121164A2 (en)	2009-04-17	2010-10-21	The Regents Of The University Of Michigan	1,4-benzodiazepinone compounds and their use in treating cancer
EP2470020A4 (de)	2009-09-18	2013-03-13	Univ Michigan	Benzodiazepinonverbindungen und behandlungsverfahren damit
WO2011062765A2 (en)	2009-11-17	2011-05-26	The Regents Of The University Of Michigan	1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
JP5856064B2 (ja)	2009-11-17	2016-02-09	ザリージェンツオブザユニバーシティオブミシガン	治療特性を有する１，４−ベンゾジアゼピン−２，５−ジオンおよび関連化合物
WO2012075456A1 (en)	2010-12-02	2012-06-07	Constellation Pharmaceuticals	Bromodomain inhibitors and uses thereof
AR084070A1 (es)	2010-12-02	2013-04-17	Constellation Pharmaceuticals Inc	Inhibidores del bromodominio y usos de los mismos
US9422292B2 (en)	2011-05-04	2016-08-23	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
WO2012174487A2 (en)	2011-06-17	2012-12-20	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
TWI602820B (zh)	2012-06-06	2017-10-21	星宿藥物公司	溴域抑制劑及其用途
US9624244B2 (en)	2012-06-06	2017-04-18	Constellation Pharmaceuticals, Inc.	Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
PL3157928T3 (pl)	2014-06-20	2019-07-31	Constellation Pharmaceuticals, Inc.	Krystaliczne postacie 2-((4S)-6-(4-chlorofenylo)-1-metylo-4H-benzo[ c]izoksazolo-[4,5-e]azepin-4-ylo)acetamidu

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3681343A (en) *	1971-05-11	1972-08-01	Upjohn Co	6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines

1974
- 1974-02-26 IE IE00393/74A patent/IE38931B1/xx unknown
- 1974-02-27 DE DE2409308A patent/DE2409308C3/de not_active Expired
- 1974-03-04 IL IL44338A patent/IL44338A/en unknown
- 1974-03-07 GB GB1035574A patent/GB1409693A/en not_active Expired
- 1974-03-08 DD DD177060A patent/DD110497A5/xx unknown
- 1974-03-08 CA CA194,513A patent/CA1011333A/en not_active Expired
- 1974-03-08 ES ES424067A patent/ES424067A1/es not_active Expired
- 1974-03-08 DK DK125874AA patent/DK139099B/da unknown
- 1974-03-08 US US05/449,477 patent/US4110337A/en not_active Expired - Lifetime
- 1974-03-08 CH CH332374A patent/CH589084A5/xx not_active IP Right Cessation
- 1974-03-08 NO NO740833A patent/NO139048C/no unknown
- 1974-03-09 JP JP49026797A patent/JPS49125395A/ja active Pending
- 1974-03-11 NL NL7403247A patent/NL7403247A/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU6627674A (en)	1975-09-11
DE2409308A1 (de)	1974-09-19
IE38931L (en)	1974-09-09
JPS49125395A (de)	1974-11-30
DK139099C (de)	1979-05-28
ES424067A1 (es)	1976-06-01
NL7403247A (de)	1974-09-11
US4110337A (en)	1978-08-29
IL44338A0 (en)	1974-06-30
IE38931B1 (en)	1978-07-05
DE2409308C3 (de)	1978-05-18
CH589084A5 (de)	1977-06-30
NO139048B (no)	1978-09-18
NO740833L (no)	1974-09-10
DE2409308B2 (de)	1977-09-22
GB1409693A (en)	1975-10-15
DK139099B (da)	1978-12-18
DD110497A5 (de)	1974-12-20
IL44338A (en)	1977-01-31
CA1011333A (en)	1977-05-31

Publication	Publication Date	Title
NO139048C (no)	1979-01-03	Analogifremgangsmaate for fremstilling av nye analgetisk og/eller antiinflammatorisk virksomme (4h)-5,6-dihydro-(4,3-a)-s-triazolo-1,5-benzodiazepiner
SE435713B (sv)	1984-10-15	Forfarande for framstellning av 1,3-bensoxazoler
AR206514A1 (es)	1976-07-30	Procedimiento para preparar derivados de s-triazol-(4,3-b)-piridacinas substituidas
FR2278691A2 (fr)	1976-02-13	Preparation de la 2,2-dioxo-6-methyl-3,4-dihydro-1,2,3-oxathiazine-4-one
SE391925B (sv)	1977-03-07	Forfarande for framstellning av 9-(substituerad amino)-imidazo/4,5-f/kinoliner
AR211006A1 (es)	1977-10-14	Procedimiento para preparar nuevos derivados de la 2-hidroxi-4-flourobutiprofenona depresores del sistema nervioso central.
BE813021A (fr)	1974-07-15	Nouveaux derives de pyrido(1
NO781340L (no)	1975-05-21	Anvendelse av derivater av blokkopolymerer
IT1055549B (it)	1982-01-11	Derivati azetidinioi e procedimento per la loro preparazione ed impiego
AR203653A1 (es)	1975-09-30	Procedimiento para la obtencion de derivados de 3,4-dihidro-2h-naftalinona-(1)-5-oxi-propil-piperazina
AR217034A1 (es)	1980-02-29	Procedimiento para la preparacion de derivados de 2-cloro-6h-tieno-(3,2-f)-c-triazol-(4,3-a)(,4)diazepina
SE419443B (sv)	1981-08-03	Forfarande for framstellning av nya 2,4 diamino-5-bensylpyrimidinderivat
TR18255A (tr)	1976-11-10	N-silfenillenmis 2,3-dihidrobenzofuranil-7-metil karbamatlar bunlarin hazirlanmasina mahsus usuller ve bunlarin ensekstisidler olarak kullanilmalari
IT1019398B (it)	1977-11-10	Procedimento per la n alchilazione di ammine aromatiche
IT1002076B (it)	1976-05-20	Coloranti e procedimento per la loro preparazione
SE7700792L (sv)	1977-01-26	Forfarande for framstellning av n,n'-diklor-isoftalsyraamid
AR205800A1 (es)	1976-06-07	Procedimiento para la preparacion de nuevos derivados de 3,4-difenil-imidazolina
FI55664C (fi)	1979-09-10	Foerfarande foer framstaellning av blodtryckssaenkande 5-oxo-2,3-dihydro-imidazo-(1,2-a)-s-triaziner
AR203399A1 (es)	1975-09-08	Nuevos derivados de 1,2-oxafosfolanos
AR204535A1 (es)	1976-02-12	Procedimiento para la preparacion de derivados de 6-fenil-4h-s-triazolo(4,3-a)-1,4-benzodiacepina
BE822765A (fr)	1975-03-14	Derives d'acides alpha-aminoxyhydroxamiques substitues
SE407689B (sv)	1979-04-09	Forfarande for framstellning av 2,2'-anhydro-1beta-d-arabinofuranosyl-5-fluorcytosin
SE413025B (sv)	1980-03-31	Forfarande for framstellning av nya 6,7-bensomorfanderivat
IT994973B (it)	1975-10-20	Procedimento per la preparazione di i aza 2 idrossibenzantrone
BE785574A (fr)	1972-12-29	Preparation de 2(aryl)-as-triazine-3,5(2h,4h)-diones