NO145382C - Analogifremgangsmaate til fremstilling av terapeutisk aktive 3-amino-indazolkarboksylsyrederivater. - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive 3-amino-indazolkarboksylsyrederivater.

Info

Publication number: NO145382C
Authority: NO; Norway
Prior art keywords: amino; preparation; acid derivatives; therapeutic active; analogue procedure
Prior art date: 1974-12-13

Application number

NO754024A

Other languages

English (en)

Other versions

NO145382B (no

NO754024L (no

Inventor

Karl Heinrich Mayer

Siegfried Petersen

Erich Klauke

Friedrich Hoffmeister

Wolfgang Wuttke

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-12-13

Filing date

1975-11-28

Publication date

1982-03-10

1975-11-28 Application filed by Bayer Ag filed Critical Bayer Ag

1976-06-15 Publication of NO754024L publication Critical patent/NO754024L/no

1981-11-30 Publication of NO145382B publication Critical patent/NO145382B/no

1982-03-10 Publication of NO145382C publication Critical patent/NO145382C/no

Links

ZQEIOHDJCAINLJ-UHFFFAOYSA-N 3-aminoindazole-3-carboxylic acid Chemical class C1=CC=C2C(N)(C(O)=O)N=NC2=C1 ZQEIOHDJCAINLJ-UHFFFAOYSA-N 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO754024A 1974-12-13 1975-11-28 Analogifremgangsmaate til fremstilling av terapeutisk aktive 3-amino-indazolkarboksylsyrederivater. NO145382C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2458965A DE2458965C3 (de)	1974-12-13	1974-12-13	3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (3)

Publication Number	Publication Date
NO754024L NO754024L (no)	1976-06-15
NO145382B NO145382B (no)	1981-11-30
NO145382C true NO145382C (no)	1982-03-10

Family

ID=5933305

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO754024A NO145382C (no)	1974-12-13	1975-11-28	Analogifremgangsmaate til fremstilling av terapeutisk aktive 3-amino-indazolkarboksylsyrederivater.

Country Status (27)

Country	Link
US (1)	US4051252A (no)
JP (1)	JPS5182266A (no)
AT (1)	AT343653B (no)
BE (1)	BE836528A (no)
CA (1)	CA1059523A (no)
CH (1)	CH622250A5 (no)
CS (1)	CS189731B2 (no)
DD (1)	DD125484A5 (no)
DE (1)	DE2458965C3 (no)
DK (1)	DK137082C (no)
ES (1)	ES443429A1 (no)
FI (1)	FI753493A7 (no)
FR (1)	FR2293928A1 (no)
GB (1)	GB1490306A (no)
HK (1)	HK52580A (no)
HU (1)	HU173557B (no)
IE (1)	IE42208B1 (no)
IL (1)	IL48642A (no)
KE (1)	KE3078A (no)
LU (1)	LU73993A1 (no)
NL (1)	NL7514521A (no)
NO (1)	NO145382C (no)
PL (1)	PL99858B1 (no)
SE (1)	SE419645B (no)
SU (1)	SU604487A3 (no)
YU (1)	YU315275A (no)
ZA (1)	ZA757777B (no)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
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US4431657A (en) *	1982-05-24	1984-02-14	Ayerst, Mckenna & Harrison Inc.	Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) *	2000-03-02	2001-09-15	성재갑	아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
ES2266258T3 (es)	2000-09-15	2007-03-01	Vertex Pharmaceuticals Incorporated	Compuestos de pirazol utiles como inhibidores de proteina cinasas.
US7473691B2 (en) *	2000-09-15	2009-01-06	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
CN1926132B (zh) *	2000-09-15	2010-12-29	沃泰克斯药物股份有限公司	可用作蛋白激酶抑制剂的吡唑化合物
US6660731B2 (en)	2000-09-15	2003-12-09	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
EP1698627A1 (en) *	2000-09-15	2006-09-06	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
EP1345925B1 (en) *	2000-12-21	2006-05-17	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
KR100406634B1 (ko) *	2001-03-12	2003-11-20	주식회사 엘지생명과학	3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
CZ2004359A3 (cs)	2001-09-26	2004-09-15	Pharmacia Italia S.P.A.	Aminoindazolové deriváty aktivní jako inhibitory kinázy, způsob jejich přípravy a farmaceutické prostředky obsahující tyto deriváty
RU2004126671A (ru) *	2002-02-06	2005-04-10	Вертекс Фармасьютикалз Инкорпорейтед (Us)	Гетероарилсоединения, полезные в качестве ингибиторов gsk-3
FR2836915B1 (fr) *	2002-03-11	2008-01-11	Aventis Pharma Sa	Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
EP1485380B1 (en)	2002-03-15	2010-05-19	Vertex Pharmaceuticals Incorporated	Azolylaminoazines as inhibitors of protein kinases
JP4751063B2 (ja)	2002-05-17	2011-08-17	ファイザーイタリアソシエタアレスポンサビリタリミタータ	キナーゼ阻害剤として活性のアミノインダゾール誘導体、それらの調製方法、及びそれらを含む薬学的組成物
MY141867A (en)	2002-06-20	2010-07-16	Vertex Pharma	Substituted pyrimidines useful as protein kinase inhibitors
ES2273043T3 (es)	2002-08-02	2007-05-01	Vertex Pharmaceuticals Incorporated	Composiciones de pirazol utiles como inhibidores de gsk-3.
AU2003270701B2 (en) *	2002-10-31	2009-11-12	Amgen Inc.	Antiinflammation agents
WO2004072029A2 (en)	2003-02-06	2004-08-26	Vertex Pharmaceuticals Incorporated	Pyrazolopyridazines useful as inhibitors of protein kinases
US7592340B2 (en) *	2003-12-04	2009-09-22	Vertex Pharmaceuticals Incorporated	Quinoxalines useful as inhibitors of protein kinases
DE102004005172A1 (de) *	2004-02-02	2005-08-18	Aventis Pharma Deutschland Gmbh	Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
CA2619517A1 (en)	2005-08-18	2007-02-22	Michael Mortimore	Pyrazine kinase inhibitors
WO2007056163A2 (en) *	2005-11-03	2007-05-18	Vertex Pharmaceuticals Incorporated	Aminopyrimidines useful as kinase inhibitors
AU2007238019B2 (en) *	2006-04-14	2013-03-14	Abbvie Inc.	Process for the preparation of indazolyl ureas that inhibit vanilloid subtype 1 (VR1) receptors
MX2009004807A (es)	2006-11-02	2009-06-15	Vertex Pharma	Aminopiridinas y aminopirimidinas utiles como inhibidores de proteina cinasa.
JP2010513567A (ja)	2006-12-19	2010-04-30	バーテックスファーマシューティカルズインコーポレイテッド	プロテインキナーゼの阻害剤として有用なアミノピリミジン
WO2008112642A1 (en)	2007-03-09	2008-09-18	Vertex Pharmaceuticals Incorporated	Aminopyrimidines useful as inhibitors of protein kinases
ATE526328T1 (de)	2007-03-09	2011-10-15	Vertex Pharma	Als inhibitoren von proteinkinasen geeignete aminopyrimidine
WO2008112646A1 (en)	2007-03-09	2008-09-18	Vertex Pharmaceuticals Incorporated	Aminopyridines useful as inhibitors of protein kinases
CA2683785A1 (en)	2007-04-13	2008-10-23	Vertex Pharmaceuticals Incorporated	Aminopyrimidines useful as kinase inhibitors
MX2009011812A (es)	2007-05-02	2010-01-14	Vertex Pharma	Aminopirimidinas utiles como inhibidores de cinasa.
CA2685876A1 (en)	2007-05-02	2008-11-13	Vertex Pharmaceuticals Incorporated	Thiazoles and pyrazoles useful as kinase inhibitors
MX2009011811A (es) *	2007-05-02	2010-01-14	Vertex Pharma	Aminopirimidinas utiles como inhibidores de cinasa.
CN101687852A (zh) *	2007-05-24	2010-03-31	沃泰克斯药物股份有限公司	可用作激酶抑制剂的噻唑类和吡唑类化合物
AR067762A1 (es)	2007-07-31	2009-10-21	Vertex Pharma	Proceso para preparar 5-fluoro-1h-pirazolo (3,4-b) piridin-3-amina y derivados de la misma
KR20110050549A (ko) *	2008-09-03	2011-05-13	버텍스 파마슈티칼스 인코포레이티드	공-결정 및 이를 포함하는 제약 제제
DE102009004245A1 (de)	2009-01-09	2010-07-15	Bayer Schering Pharma Aktiengesellschaft	Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
ES2667056T3 (es)	2012-07-24	2018-05-09	Bial-Portela & Ca, S.A.	Compuestos de urea y su uso como inhibidores enzimáticos
CN104662002A (zh) *	2012-07-27	2015-05-27	比亚尔-珀特拉和Ca股份公司	取代脲类化合物的合成方法
KR20160034359A (ko)	2013-07-24	2016-03-29	바이알 - 포르텔라 앤드 씨에이 에스에이	이미다졸카복스아미드 및 faah 억제제로서 이들의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3133081A (en) *		1964-05-12		J-aminoindazole derivatives
CH397698A (de) *	1961-09-08	1965-08-31	Siegfried Ag	Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3277100A (en) *	1963-05-31	1966-10-04	Du Pont	Novel substituted pyrazoles
NL6707299A (no) *	1966-07-16	1968-01-17
DE1770649A1 (de) *	1968-06-15	1971-11-11	Bayer Ag	Substituierte 3-Amino-indazole

1974
- 1974-12-13 DE DE2458965A patent/DE2458965C3/de not_active Expired
1975
- 1975-10-28 GB GB44299/75A patent/GB1490306A/en not_active Expired
- 1975-11-24 US US05/634,914 patent/US4051252A/en not_active Expired - Lifetime
- 1975-11-27 CA CA240,662A patent/CA1059523A/en not_active Expired
- 1975-11-28 NO NO754024A patent/NO145382C/no unknown
- 1975-12-02 CS CS758165A patent/CS189731B2/cs unknown
- 1975-12-08 SU SU752195302A patent/SU604487A3/ru active
- 1975-12-09 CH CH1599575A patent/CH622250A5/de not_active IP Right Cessation
- 1975-12-10 IL IL48642A patent/IL48642A/xx unknown
- 1975-12-11 LU LU73993A patent/LU73993A1/xx unknown
- 1975-12-11 HU HU75BA3349A patent/HU173557B/hu unknown
- 1975-12-11 AT AT939775A patent/AT343653B/de not_active IP Right Cessation
- 1975-12-11 PL PL1975185475A patent/PL99858B1/pl unknown
- 1975-12-11 JP JP50146940A patent/JPS5182266A/ja active Pending
- 1975-12-11 SE SE7513990A patent/SE419645B/xx unknown
- 1975-12-11 FI FI753493A patent/FI753493A7/fi not_active Application Discontinuation
- 1975-12-11 BE BE162651A patent/BE836528A/xx unknown
- 1975-12-11 DD DD190061A patent/DD125484A5/xx unknown
- 1975-12-12 IE IE2714/75A patent/IE42208B1/en unknown
- 1975-12-12 YU YU03152/75A patent/YU315275A/xx unknown
- 1975-12-12 NL NL7514521A patent/NL7514521A/xx not_active Application Discontinuation
- 1975-12-12 DK DK567275A patent/DK137082C/da active
- 1975-12-12 ES ES443429A patent/ES443429A1/es not_active Expired
- 1975-12-12 FR FR7538124A patent/FR2293928A1/fr active Granted
- 1975-12-12 ZA ZA757777A patent/ZA757777B/xx unknown
1980
- 1980-08-29 KE KE3078A patent/KE3078A/xx unknown
- 1980-09-18 HK HK525/80A patent/HK52580A/xx unknown

Also Published As

Publication number	Publication date
DE2458965C3 (de)	1979-10-11
FR2293928B1 (no)	1979-09-21
IL48642A0 (en)	1976-02-29
AT343653B (de)	1978-06-12
DK137082C (da)	1978-06-19
IL48642A (en)	1979-12-30
US4051252A (en)	1977-09-27
YU315275A (en)	1982-02-28
GB1490306A (en)	1977-11-02
DD125484A5 (no)	1977-04-20
BE836528A (fr)	1976-06-11
KE3078A (en)	1980-10-03
DE2458965A1 (de)	1976-06-16
ZA757777B (en)	1976-11-24
IE42208L (en)	1976-06-13
NO145382B (no)	1981-11-30
CA1059523A (en)	1979-07-31
NO754024L (no)	1976-06-15
CH622250A5 (no)	1981-03-31
FI753493A7 (no)	1976-06-14
HK52580A (en)	1980-09-26
DK567275A (da)	1976-06-14
HU173557B (hu)	1979-06-28
ES443429A1 (es)	1977-04-16
FR2293928A1 (fr)	1976-07-09
AU8717075A (en)	1977-06-09
JPS5182266A (en)	1976-07-19
SU604487A3 (ru)	1978-04-25
NL7514521A (nl)	1976-06-15
ATA939775A (de)	1977-10-15
DK137082B (da)	1978-01-16
PL99858B1 (pl)	1978-08-31
CS189731B2 (en)	1979-04-30
IE42208B1 (en)	1980-06-18
SE419645B (sv)	1981-08-17
LU73993A1 (no)	1976-11-11
DE2458965B2 (de)	1979-02-22
SE7513990L (sv)	1976-06-14

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NO148375C (no)	1983-09-28	Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-klor-7-alfa-amino-acylcefalosporinforbindelser
NO142838C (no)	1980-10-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater
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NO143459C (no)	1981-02-18	Analogifremgangsmaate for fremstilling av fysiologisk aktive 2-fenylimino-imidazolidin-derivater
NO144773C (no)	1981-11-04	Analogifremgangsmaate til fremstilling av terapeutisk aktive aminer.
SE400551B (sv)	1978-04-03	Forfarande for framstellning av terapeutiskt aktiva 3-amino-5-karbamylbensoesyraderivat
NO144928C (no)	1981-12-09	Analogifremgangsmaate for fremstilling av fysiologisk aktive zantinderivater.
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