NO166131C - Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser.

Info

Publication number
NO166131C
NO166131C NO862426A NO862426A NO166131C NO 166131 C NO166131 C NO 166131C NO 862426 A NO862426 A NO 862426A NO 862426 A NO862426 A NO 862426A NO 166131 C NO166131 C NO 166131C
Authority
NO
Norway
Prior art keywords
compounds
pyridobenzoksazine
preparation
preparing
optically active
Prior art date
Application number
NO862426A
Other languages
English (en)
Norwegian (no)
Other versions
NO166131B (no
NO862426D0 (no
NO862426L (no
Inventor
Isao Hayakawa
Shohgo Atarashi
Shuichi Yokohama
Masazumi Imamura
Katsuichi Sakano
Nobuyuki Higashihashi
Masayuki Ohshima
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27281433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO166131(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP60226499A external-priority patent/JPH0720946B2/ja
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO862426D0 publication Critical patent/NO862426D0/no
Publication of NO862426L publication Critical patent/NO862426L/no
Priority to NO883791A priority Critical patent/NO169896C/no
Publication of NO166131B publication Critical patent/NO166131B/no
Publication of NO166131C publication Critical patent/NO166131C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO862426A 1985-06-20 1986-06-18 Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser. NO166131C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO883791A NO169896C (no) 1985-06-20 1988-08-25 3-s-3-alkylbenzoksazinderivater

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13471285 1985-06-20
JP60226499A JPH0720946B2 (ja) 1985-10-11 1985-10-11 光学活性３−メチルベンゾオキサジン誘導体およびその製法
JP1649686 1986-01-28

Publications (4)

Publication Number Publication Date
NO862426D0 NO862426D0 (no) 1986-06-18
NO862426L NO862426L (no) 1986-12-22
NO166131B NO166131B (no) 1991-02-25
NO166131C true NO166131C (no) 1991-06-05

Family

ID=27281433

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862426A NO166131C (no) 1985-06-20 1986-06-18 Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser.

Country Status (16)

Country Link
US (3) US5053407A (de)
EP (1) EP0206283B1 (de)
KR (2) KR920010048B1 (de)
AT (1) ATE85057T1 (de)
BG (1) BG60527B2 (de)
CA (1) CA1304080C (de)
DE (2) DE3687599T2 (de)
DK (1) DK170473B1 (de)
ES (1) ES8801251A1 (de)
FI (1) FI90241C (de)
GR (1) GR861625B (de)
HK (1) HK91793A (de)
IE (1) IE59463B1 (de)
NL (1) NL980016I2 (de)
NO (1) NO166131C (de)
YU (3) YU44918B (de)

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IE75342B1 (en) * 1987-12-25 1997-08-27 Daiichi Seiyaku Co Propoxybenzene derivatives and process for preparing the same
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AU4376589A (en) * 1988-11-07 1990-05-10 Gist-Brocades N.V. Optically active benzoxazines and benzothiazines
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
FR2655545B1 (fr) * 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
TW208013B (de) * 1990-03-01 1993-06-21 Daiichi Co Ltd
NO179912C (no) * 1990-11-28 1997-01-08 Daiichi Seiyaku Co Analogifremgangsmåte for fremstilling av et terapeutisk virksomt optisk aktivt pyridobenzoksazinderivat
ES2055656B1 (es) * 1992-10-07 1995-11-16 Etilo Derivados Procedimiento para la obtencion de benzoxazinas utiles para sintesis de ofloxacina, levofloxacina y derivados.
AU674542B2 (en) * 1992-10-07 1997-01-02 Derivados Del Etilo, S.A. Process for obtaining benzoxazines useful for the synthesis of ofloxacin, levofloxacin and derivatives thereof
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
US5686095A (en) * 1995-10-23 1997-11-11 Price, Jr.; Francis W. Method of treating canker sores
EP0934061B3 (de) 1996-07-24 2015-01-21 Warner-Lambert Company LLC Isobutylgaba und dessen derivate zur schmerzbehandlung
US6022551A (en) * 1998-01-20 2000-02-08 Ethicon, Inc. Antimicrobial composition
US6248343B1 (en) 1998-01-20 2001-06-19 Ethicon, Inc. Therapeutic antimicrobial compositions
US5972358A (en) * 1998-01-20 1999-10-26 Ethicon, Inc. Low tack lotion, gels and creams
US5997893A (en) * 1998-01-20 1999-12-07 Ethicon, Inc. Alcohol based anti-microbial compositions with cosmetic appearance
KR100309871B1 (ko) 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
AU757777B2 (en) 1998-12-04 2003-03-06 Influx, Inc. Inhibitors of multidrug transporters
KR100617952B1 (ko) * 1999-03-04 2006-08-30 보령제약 주식회사 광학활성 피리도 벤즈옥사진 유도체의 제조방법
JP4302350B2 (ja) 1999-09-08 2009-07-22 第一三共株式会社 ベンゾオキサジン誘導体の製造法およびその製造中間体
KR20010103346A (ko) * 2000-05-09 2001-11-23 이후근 패각 입자와 접착제 그리고 물감을 혼합하여 그림 밑칠용재료를 제조하는 방법
EP1349853B1 (de) * 2000-12-21 2006-03-08 Pharmacia & Upjohn Company LLC Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
WO2002070726A1 (en) 2001-03-07 2002-09-12 Daiichi Pharmaceutical Co., Ltd. Process for preparation of optically active propoxyaniline derivatives
WO2002088411A1 (en) 2001-04-27 2002-11-07 Research Institute Of Industrial Science & Technology High manganese duplex stainless steel having superior hot workabilities and method for manufacturing thereof
US7425628B2 (en) 2001-10-03 2008-09-16 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
PT1451194E (pt) 2001-10-03 2007-01-31 Teva Pharma Preparação de hemi-hidrato de levofloxacina
KR100440192B1 (ko) * 2001-11-22 2004-07-12 이수화학 주식회사 광학 활성 퀴놀론카르복실산 유도체의 제조방법
AU2002365416A1 (en) * 2001-11-29 2003-06-10 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
EA006053B1 (ru) * 2001-12-24 2005-08-25 Тева Фармасьютикал Индастриес Лтд. Твёрдая лекарственная форма, способ её изготовления и устройство
EP2316468A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
JP2006516152A (ja) 2002-08-14 2006-06-22 テバ ファーマシューティカル インダストリーズ リミティド ガチフロキサシンの合成
US20040152701A1 (en) * 2002-12-02 2004-08-05 Dr. Reddy's Laboratories Limited Novel anhydrous crystalline form of Levofloxacin and process for preparation there of
FR2859471B1 (fr) 2003-09-09 2006-02-03 Solvay Procede pour la fabrication d'un compose enantiopur
JP5203696B2 (ja) 2005-02-07 2013-06-05 田辺三菱製薬株式会社 光学活性なテトラヒドロナフタレン誘導体
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US20090264342A1 (en) * 2006-02-13 2009-10-22 Trustees Of Boston University Compositions and methods for antibiotic potentiation and drug discovery
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20100234348A1 (en) * 2006-08-04 2010-09-16 Trustees Of Boston University Compositions and methods for potentiating antibiotic activity
EP1939206A1 (de) * 2006-12-22 2008-07-02 Farmaprojects, S.A. Herstellungsverfahren für eine antibakterielle Quinolonverbindung
US20100029938A1 (en) * 2006-12-22 2010-02-04 Farmaprojects, S. A. Process for the preparation of an antibacterial quinolone compound
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CN102325532B (zh) 2008-10-07 2015-06-17 Mpex医药有限公司 用于减轻肺部炎症的左氧氟沙星吸入剂
AU2009302478B2 (en) 2008-10-07 2015-09-03 Horizon Orphan Llc Aerosol fluoroquinolone formulations for improved pharmacokinetics
BRPI1010981A2 (pt) 2009-05-15 2018-12-04 Redx Pharma Ltd "derivados de fármaco redox"
CN101659669B (zh) * 2009-09-04 2011-07-20 诚达药业股份有限公司 左旋氧氟沙星的制备方法
LT2473170T (lt) 2009-09-04 2019-10-10 Horizon Orphan Llc Aerozolizuoto levofloksacino panaudojimas cistinės fibrozės gydymui
CN102775424A (zh) * 2012-07-09 2012-11-14 浙江司太立制药股份有限公司 一种左氧氟沙星杂质的制备方法
WO2014152332A1 (en) 2013-03-15 2014-09-25 Melinta Therapeutics, Inc. Methods of treating infections in overweight and obese patients using antibiotics
ES2988983T3 (es) * 2014-05-09 2024-11-22 Tecnimede Sociedade Tecnico Medicinal S Sales de mandelato de enantiómeros de pirlindol para uso en medicina
CN105037388A (zh) * 2015-08-28 2015-11-11 安徽环球药业股份有限公司 一种安妥沙星的制备方法
CN105367585B (zh) * 2015-12-02 2017-11-17 山东齐都药业有限公司 左氧氟沙星杂质的制备方法
EP4149427A1 (de) 2020-06-11 2023-03-22 Sentiss Pharma Private Limited Ophthalmische zusammensetzungen mit einer kombination aus einem antibakteriellen fluorchinolonmittel und einem entzündungshemmenden mittel

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JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
JPS5852290A (ja) * 1981-09-21 1983-03-28 Dai Ichi Seiyaku Co Ltd ピリドベンゾオキサジンカルボン酸誘導体
DE3543513A1 (de) * 1985-12-10 1987-06-11 Bayer Ag Enantiomerenreine 1,8-verbrueckte 4-chinolon-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel und ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
US5053407A (en) 1991-10-01
NL980016I1 (nl) 1998-07-01
DK285086D0 (da) 1986-06-18
EP0206283A2 (de) 1986-12-30
FI90241C (fi) 1994-01-10
FI862643A0 (fi) 1986-06-19
KR920009279A (ko) 1992-05-28
IE861631L (en) 1986-12-20
DE3687599T2 (de) 1993-05-19
ES556292A0 (es) 1988-01-01
US4985557A (en) 1991-01-15
YU45524B (en) 1992-05-28
ES8801251A1 (es) 1988-01-01
NL980016I2 (nl) 1998-08-03
YU44918B (en) 1991-04-30
DE3687599D1 (de) 1993-03-11
BG60527B2 (bg) 1995-07-28
EP0206283A3 (en) 1988-08-10
KR920010048B1 (ko) 1992-11-13
CA1304080C (en) 1992-06-23
DK170473B1 (da) 1995-09-11
YU107386A (en) 1988-02-29
GR861625B (en) 1986-10-21
US5142046A (en) 1992-08-25
YU209889A (en) 1990-04-30
HK91793A (en) 1993-09-10
DK285086A (da) 1986-12-21
KR870000340A (ko) 1987-02-17
NO166131B (no) 1991-02-25
FI90241B (fi) 1993-09-30
ATE85057T1 (de) 1993-02-15
YU186788A (en) 1989-04-30
DE19875012I2 (de) 2006-06-29
EP0206283B1 (de) 1993-01-27
FI862643A7 (fi) 1986-12-21
YU45512B (en) 1992-05-28
KR940003757B1 (ko) 1994-04-30
IE59463B1 (en) 1994-02-23
NO862426D0 (no) 1986-06-18
NO862426L (no) 1986-12-22

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