NO169900C - Analogifremgangsmaate for fremstilling av terapeutisk aktive (ih-azol-1-ylmetyl)substituerte benzotriazolderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive (ih-azol-1-ylmetyl)substituerte benzotriazolderivater

Info

Publication number: NO169900C
Authority: NO; Norway
Prior art keywords: azol; ylmethyl; preparation; therapeutic active; analogue procedure
Prior art date: 1987-06-01

Application number

NO882390A

Other languages

English (en)

Norwegian (no)

Other versions

NO169900B (no

NO882390D0 (no

NO882390L (no

Inventor

Alfons Herman Marg Raeymaekers

Eddy Jean Edgard Freyne

Josephus Ludovicus Hube Gelder

Marc Gaston Venet

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-01

Filing date

1988-05-31

Publication date

1992-08-19

1988-05-31 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1988-05-31 Publication of NO882390D0 publication Critical patent/NO882390D0/no

1988-12-02 Publication of NO882390L publication Critical patent/NO882390L/no

1992-05-11 Publication of NO169900B publication Critical patent/NO169900B/no

1992-08-19 Publication of NO169900C publication Critical patent/NO169900C/no

Links

QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical class C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO882390A 1987-06-01 1988-05-31 Analogifremgangsmaate for fremstilling av terapeutisk aktive (ih-azol-1-ylmetyl)substituerte benzotriazolderivater NO169900C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5602187A	1987-06-01	1987-06-01

Publications (4)

Publication Number	Publication Date
NO882390D0 NO882390D0 (no)	1988-05-31
NO882390L NO882390L (no)	1988-12-02
NO169900B NO169900B (no)	1992-05-11
NO169900C true NO169900C (no)	1992-08-19

Family

ID=22001654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO882390A NO169900C (no)	1987-06-01	1988-05-31	Analogifremgangsmaate for fremstilling av terapeutisk aktive (ih-azol-1-ylmetyl)substituerte benzotriazolderivater

Country Status (24)

Country	Link
EP (1)	EP0293978B1 (da)
JP (1)	JPH0662612B2 (da)
KR (1)	KR970000952B1 (da)
CN (1)	CN1022184C (da)
AU (1)	AU603446B2 (da)
BG (2)	BG50278A3 (da)
CA (1)	CA1307271C (da)
CY (1)	CY1866A (da)
DE (1)	DE3884055T2 (da)
DK (1)	DK175218B1 (da)
ES (1)	ES2059490T3 (da)
FI (1)	FI90078C (da)
HK (1)	HK114795A (da)
HU (2)	HU201056B (da)
IE (1)	IE61823B1 (da)
IL (1)	IL86551A (da)
LT (1)	LT3950B (da)
LV (1)	LV10452B (da)
NO (1)	NO169900C (da)
NZ (1)	NZ224714A (da)
PT (1)	PT87623B (da)
RU (1)	RU1838308C (da)
UA (1)	UA11192A (da)
ZA (1)	ZA883861B (da)

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CA2002859C (en) *	1988-11-29	1998-12-29	Jean P. F. Van Wauwe	Method of treating epithelial disorders
US5157046A (en) *	1988-11-29	1992-10-20	Janssen Pharmaceutica N.V.	Method of treating epithelial disorders
GB8827820D0 (en) *	1988-11-29	1988-12-29	Janssen Pharmaceutica Nv	(1h-azol-1-ylmethyl)substituted quinoline derivatives
DE59010171D1 (de) *	1989-07-14	1996-04-11	Ciba Geigy Ag	Substituierte Benzonitrile
CA2026792A1 (en) *	1989-11-01	1991-05-02	Michael N. Greco	(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1h-benzotriazole derivatives
US5066656A (en) *	1989-11-01	1991-11-19	Janssen Pharmaceutica N.V.	Pharmacologically active (6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1H-benzotriazole derivatives
NZ236440A (en) *	1989-12-15	1993-07-27	Merck & Co Inc	Reversal of sexual phenotype in poultry using an inhibitor of steroid biotransformation and/or aromatase inhibitor, poultry produced by this process
AU7124691A (en) *	1990-02-27	1991-08-29	Ciba-Geigy Ag	Benzofurans
DE4010797A1 (de) *	1990-04-04	1991-10-10	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
EP0457716A1 (de) *	1990-04-20	1991-11-21	Ciba-Geigy Ag	Naphthalinderivate
TW224461B (da) *	1990-09-18	1994-06-01	Ciba Geigy Ag
US5162337A (en) *	1990-10-05	1992-11-10	Merck & Co., Inc.	Animal growth promotion
TW210334B (da) *	1990-12-12	1993-08-01	Ciba Geigy Ag
CH683151A5 (de) *	1991-04-24	1994-01-31	Ciba Geigy Ag	Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
EP0641785B1 (en) *	1991-09-02	1999-10-27	Yamanouchi Pharmaceutical Co. Ltd.	Triazolylated tertiary amine compound or salt thereof
US5635521A (en) *	1991-09-23	1997-06-03	Sandoz Ltd.	Imidazolylmethyl-pyridines
JP2700595B2 (ja) *	1992-05-21	1998-01-21	呉羽化学工業株式会社	アゾール誘導体を含有する抗アロマターゼ剤
JPH08502990A (ja) *	1992-11-10	1996-04-02	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	鏡像体的に純粋な６−［（４−クロロフェニル）（１ｈ−１，２，４−トリアゾール−１−イル）メチル−１−メチル−１ｈ−ベンゾトリアゾールの製造方法
EP0684235A1 (en) *	1994-05-27	1995-11-29	Mochida Pharmaceutical Co., Ltd.	Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity
WO1997006788A1 (en) *	1995-08-14	1997-02-27	Janssen Pharmaceutica N.V.	Transdermal administration of vorozole
IT1286866B1 (it) *	1996-10-28	1998-07-17	Menarini Farma Ind	Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
KR100559816B1 (ko) *	1996-12-24	2006-03-10	쥬가이 세이야쿠 가부시키가이샤	Ｎｏｓ 저해작용을 가진 방향족 아민 유도체
EP1295880A4 (en) *	2000-06-28	2004-05-06	Ssp Co Ltd	IMIDAZOLE DERIVATIVES OR THEIR SALTS AND THE MEDICINES CONTAINING THEM
US7135575B2 (en)	2003-03-03	2006-11-14	Array Biopharma, Inc.	P38 inhibitors and methods of use thereof
KR101099281B1 (ko) *	2003-03-03	2011-12-26	어레이 바이오파마 인크.	ｐ38 억제제 및 그의 사용 방법
EP1845973B1 (en)	2005-01-21	2015-08-12	Astex Therapeutics Limited	Pharmaceutical compounds
EP1874304B1 (en) *	2005-04-29	2009-07-15	Janssen Pharmaceutica N.V.	Benzotriazole derivatives as cannabinoid receptor antagonists
US7572807B2 (en)	2005-06-09	2009-08-11	Bristol-Myers Squibb Company	Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
CN101291950B (zh)	2005-09-15	2013-01-02	科学与工业研究会	咪唑基取代的类固醇和茚满-1-酮衍生物
WO2007089646A1 (en)	2006-01-31	2007-08-09	Array Biopharma Inc.	Kinase inhibitors and methods of use thereof
US8883790B2 (en)	2006-10-12	2014-11-11	Astex Therapeutics Limited	Pharmaceutical combinations
US8916552B2 (en)	2006-10-12	2014-12-23	Astex Therapeutics Limited	Pharmaceutical combinations
JP2013540145A (ja) *	2010-10-21	2013-10-31	ウニベルシテートデスザールランデス	コルチゾール依存性疾患の治療用の選択的ｃｙｐ１１ｂ１阻害剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR75101B (da) *	1980-10-23	1984-07-13	Pfizer
US4602025A (en) *	1984-06-18	1986-07-22	Eli Lilly And Company	Aromatase inhibitors
US4659730A (en) *	1984-06-18	1987-04-21	Eli Lilly And Company	Aromatase inhibiting imidazole derivatives
US4801594A (en) *	1984-06-18	1989-01-31	Eli Lilly And Company	Aromatase inhibitors
US4609666A (en) *	1984-06-18	1986-09-02	Eli Lilly And Company	Aromatase inhibiting derivatives of α,α-bis(4-halophenyl)methyltetrazoles and triazoles
EP0165781A1 (en) *	1984-06-18	1985-12-27	Eli Lilly And Company	Aromatase inhibiting N-substituted imidazole derivatives
DE3744589C1 (de)	1987-12-31	1988-12-29	Albrecht Josef Bohrfutter	Nachspannendes Bohrfutter

1988
- 1988-05-19 NZ NZ224714A patent/NZ224714A/xx unknown
- 1988-05-20 UA UA4355784A patent/UA11192A/uk unknown
- 1988-05-20 RU SU884355784A patent/RU1838308C/ru active
- 1988-05-23 AU AU16537/88A patent/AU603446B2/en not_active Expired
- 1988-05-25 CA CA000567618A patent/CA1307271C/en not_active Expired - Lifetime
- 1988-05-26 DE DE88201061T patent/DE3884055T2/de not_active Expired - Lifetime
- 1988-05-26 ES ES88201061T patent/ES2059490T3/es not_active Expired - Lifetime
- 1988-05-26 EP EP88201061A patent/EP0293978B1/en not_active Expired - Lifetime
- 1988-05-26 CY CY186688A patent/CY1866A/xx unknown
- 1988-05-30 ZA ZA883861A patent/ZA883861B/xx unknown
- 1988-05-30 IL IL86551A patent/IL86551A/xx not_active IP Right Cessation
- 1988-05-31 DK DK198802952A patent/DK175218B1/da not_active IP Right Cessation
- 1988-05-31 FI FI882552A patent/FI90078C/fi not_active IP Right Cessation
- 1988-05-31 NO NO882390A patent/NO169900C/no not_active IP Right Cessation
- 1988-05-31 PT PT87623A patent/PT87623B/pt not_active IP Right Cessation
- 1988-05-31 IE IE164088A patent/IE61823B1/en not_active IP Right Cessation
- 1988-05-31 BG BG084328A patent/BG50278A3/xx unknown
- 1988-06-01 CN CN88103408A patent/CN1022184C/zh not_active Expired - Lifetime
- 1988-06-01 KR KR1019880006557A patent/KR970000952B1/ko not_active Expired - Lifetime
- 1988-06-01 JP JP63132886A patent/JPH0662612B2/ja not_active Expired - Lifetime
- 1988-06-01 HU HU882783A patent/HU201056B/hu unknown
1992
- 1992-11-27 LV LVP-92-233A patent/LV10452B/lv unknown
1993
- 1993-10-18 BG BG098159A patent/BG60429B2/bg unknown
- 1993-12-16 LT LTIP1625A patent/LT3950B/lt not_active IP Right Cessation
1995
- 1995-06-29 HU HU95P/P00533P patent/HU211482A9/hu unknown
- 1995-07-13 HK HK114795A patent/HK114795A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU211482A9 (en)	1995-11-28
IL86551A0 (en)	1988-11-15
NO169900B (no)	1992-05-11
LV10452A (lv)	1995-02-20
HU201056B (en)	1990-09-28
EP0293978A3 (en)	1990-06-13
FI882552A7 (fi)	1988-12-02
DK175218B1 (da)	2004-07-12
IE881640L (en)	1988-12-01
UA11192A (uk)	1996-12-25
DK295288A (da)	1988-12-02
NO882390D0 (no)	1988-05-31
CN88103408A (zh)	1988-12-14
KR970000952B1 (ko)	1997-01-21
RU1838308C (ru)	1993-08-30
CY1866A (en)	1988-05-26
HUT49132A (en)	1989-08-28
HK114795A (en)	1995-07-21
JPH0662612B2 (ja)	1994-08-17
FI90078B (fi)	1993-09-15
DK295288D0 (da)	1988-05-31
AU1653788A (en)	1988-12-01
CN1022184C (zh)	1993-09-22
DE3884055D1 (de)	1993-10-21
LT3950B (en)	1996-05-27
CA1307271C (en)	1992-09-08
BG50278A3 (bg)	1992-06-15
LV10452B (en)	1995-08-20
AU603446B2 (en)	1990-11-15
ZA883861B (en)	1990-01-31
PT87623B (pt)	1992-09-30
IE61823B1 (en)	1994-11-30
EP0293978B1 (en)	1993-09-15
FI882552A0 (fi)	1988-05-31
LTIP1625A (en)	1995-07-25
NO882390L (no)	1988-12-02
EP0293978A2 (en)	1988-12-07
BG60429B2 (bg)	1995-03-31
DE3884055T2 (de)	1994-01-27
FI90078C (fi)	1993-12-27
NZ224714A (en)	1990-03-27
KR890000469A (ko)	1989-03-14
IL86551A (en)	1992-07-15
PT87623A (pt)	1988-06-01
ES2059490T3 (es)	1994-11-16
JPS63316775A (ja)	1988-12-26

Legal Events

Date	Code	Title	Description
2008-06-23	MK1K	Patent expired

Publication	Publication Date	Title
NO164025C (no)	1990-08-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-imidazolylmetyl-tetrahydrokarbazolon-derivater.
NO883974D0 (no)	1988-09-07	Fremgangsmaate for fremstilling av terapeutiske aktive tetrahydro-hydroksypyranon-derivater.
NO169439C (no)	1992-06-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive oxadiazoler
NO172048C (no)	1993-06-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazoler
NO882732D0 (no)	1988-06-21	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO165843C (no)	1991-04-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive n-6 -substituerte adenosiner.
NO904986L (no)	1991-05-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive diazepin-derivater.
NO874153D0 (no)	1987-10-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo-benzoksazinon-derivater.
NO161497C (no)	1989-08-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 9a-aza-9a-homoerytromycin-derivater.
NO884231D0 (no)	1988-09-23	Fremgangsmaate for fremstilling av terapeutisk aktive imidazopyridin-derivater.
NO172986C (no)	1993-10-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 9h-puriner
NO172575C (no)	1993-08-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzocykloalkanderivater
NO903941D0 (no)	1990-09-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive diazepinon-derivater.
NO171214C (no)	1993-02-10	Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyridonkarboksylsyrederivater
NO158876C (no)	1988-11-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive adenosin-derivater.
NO164541C (no)	1990-10-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater.
NO167734C (no)	1991-12-04	Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte aminderivater.
NO169963C (no)	1992-08-26	Analogifremgangsmaate til fremstilling av terapeutisk aktive, substituerte 3,4-dihydro-2h-benzopyraner
NO171679C (no)	1993-04-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-fenyl-3-(1-piperazinyl)-1h-indazoler
NO902710L (no)	1990-12-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive r(-) 3-kinuklidinol-derivater.
NO884176D0 (no)	1988-09-20	Fremgangsmaate for fremstilling av terapeutisk aktive amidinoderivater.
NO169648C (no)	1992-07-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater
NO884175D0 (no)	1988-09-20	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske derivater.
NO873680D0 (no)	1987-09-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive sulfonamido-etyl-forbindelser.
NO881884D0 (no)	1988-04-29	Fremgangsmaate for fremstilling av terapeutisk aktive pyrrolidin-derivater.