NO180741C - Fremgangsmåte for isolering av Faktor VIII - Google Patents

Fremgangsmåte for isolering av Faktor VIII

Info

Publication number
NO180741C
NO180741C NO921839A NO921839A NO180741C NO 180741 C NO180741 C NO 180741C NO 921839 A NO921839 A NO 921839A NO 921839 A NO921839 A NO 921839A NO 180741 C NO180741 C NO 180741C
Authority
NO
Norway
Prior art keywords
factor viii
isolating factor
isolating
proteins
plasma
Prior art date
Application number
NO921839A
Other languages
English (en)
Norwegian (no)
Other versions
NO921839D0 (no
NO180741B (no
NO921839L (no
Inventor
Per Kaersgaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO921839D0 publication Critical patent/NO921839D0/no
Publication of NO921839L publication Critical patent/NO921839L/no
Publication of NO180741B publication Critical patent/NO180741B/no
Publication of NO180741C publication Critical patent/NO180741C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Housing For Livestock And Birds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Cephalosporin Compounds (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Networks Using Active Elements (AREA)
  • Amplifiers (AREA)
NO921839A 1989-11-09 1992-05-08 Fremgangsmåte for isolering av Faktor VIII NO180741C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK562189A DK162233C (da) 1989-11-09 1989-11-09 Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
PCT/DK1990/000279 WO1991007438A1 (en) 1989-11-09 1990-11-05 A method for isolating factor viii

Publications (4)

Publication Number Publication Date
NO921839D0 NO921839D0 (no) 1992-05-08
NO921839L NO921839L (no) 1992-07-08
NO180741B NO180741B (no) 1997-03-03
NO180741C true NO180741C (no) 1997-06-11

Family

ID=8144000

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921839A NO180741C (no) 1989-11-09 1992-05-08 Fremgangsmåte for isolering av Faktor VIII

Country Status (26)

Country Link
US (1) US5245014A (zh)
EP (1) EP0524172B1 (zh)
JP (1) JP2509407B2 (zh)
CN (1) CN1044121C (zh)
AT (1) ATE118508T1 (zh)
AU (1) AU631471B2 (zh)
BG (1) BG61231B1 (zh)
CA (1) CA2073012C (zh)
CZ (1) CZ537190A3 (zh)
DE (1) DE69017050T2 (zh)
DK (1) DK162233C (zh)
ES (1) ES2068404T3 (zh)
FI (1) FI103510B (zh)
HU (1) HU214905B (zh)
IE (1) IE66836B1 (zh)
IL (1) IL96277A (zh)
NO (1) NO180741C (zh)
NZ (1) NZ236004A (zh)
PL (1) PL164894B1 (zh)
PT (1) PT95830B (zh)
RU (1) RU2055593C1 (zh)
SK (1) SK537190A3 (zh)
UA (1) UA29421C2 (zh)
WO (1) WO1991007438A1 (zh)
YU (1) YU47524B (zh)
ZA (1) ZA908599B (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE90875T1 (de) * 1989-05-24 1993-07-15 Miles Inc Gelfiltration von waermebehandeltem faktor viii.
US6180371B1 (en) 1996-06-26 2001-01-30 Emory University Modified factor VIII
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
US5888974A (en) * 1992-04-07 1999-03-30 Emory University Hybrid human/animal factor VIII
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
US7560107B2 (en) 1996-06-26 2009-07-14 Emory University Modified factor VIII
US6531577B1 (en) * 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
US6290527B1 (en) * 1998-07-03 2001-09-18 Nippon Telegraph And Telephone Corp. Nippon telegraph and telephone corporation
EP2921180B1 (en) 1999-02-22 2019-08-14 University of Connecticut Albumin-free factor VIII formulations
JP2002348300A (ja) * 1999-04-12 2002-12-04 Fujimori Kogyo Co Ltd 血液凝固第ｖｉｉｉ因子および血液凝固第ｖｉｉｉ因子／フォン・ビルブラント因子複合体の精製方法
EP1359936B1 (en) * 2001-02-05 2008-02-20 Novo Nordisk Health Care AG Combined use of factor vii polypeptides and factor viii polypeptides
AUPR638801A0 (en) * 2001-07-13 2001-08-09 Life Therapeutics Limited Factor viii separation
RU2253475C1 (ru) * 2004-02-02 2005-06-10 Общество с ограниченной ответственностью "Гемоцентр" Способ получения препарата фактора viii
SI1750733T1 (sl) 2004-05-03 2014-03-31 Emory University POSTOPEK DAJANJA PRAĹ IÄŚJEGA fVIII BREZ DOMENE B
US20080176789A1 (en) * 2004-08-27 2008-07-24 Novc Nordisk Healthcare A/G Purification of Factor Xlll Polypeptides From Biological Materials
US20060226086A1 (en) * 2005-04-08 2006-10-12 Robinson Thomas C Centrifuge for blood processing systems
RU2324495C1 (ru) * 2006-08-31 2008-05-20 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации Способ получения препарата фактора свертывания viii крови человека
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
EP2553095B1 (en) * 2010-03-30 2016-10-12 Octapharma AG A process for purifying vitamin K dependent proteins such as coagulation factor IX
RU2445974C2 (ru) * 2010-04-26 2012-03-27 Учреждение Российской академии медицинских наук Гематологический научный центр ГНЦ РАМН Способ получения концентрата фактора viii из плазмы крови человека
JP5922141B2 (ja) 2010-11-05 2016-05-24 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 増加した比活性を有する抗血友病第ｖｉｉｉ因子の新規変異体
CA2821711C (en) 2010-12-15 2017-10-10 Baxter International Inc. Eluate collection using conductivity gradient
CN103506080A (zh) * 2012-06-19 2014-01-15 汪志友 一种用于分离纯化凝血因子viii的介质及其制备方法
CN104937423B (zh) * 2012-09-28 2017-05-24 中外制药株式会社 凝血反应的评价方法
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
DK525384D0 (da) * 1984-11-05 1984-11-05 Nordisk Insulinlab Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat
US4847362A (en) * 1985-02-01 1989-07-11 New York University Method for purifying antihemophilic factor
US4675385A (en) * 1985-03-27 1987-06-23 Alpha Therapeutic Corporation Isolation of human plasma procoagulant protein factor VIII from biological factors
US4758657A (en) * 1985-07-11 1988-07-19 Armour Pharmaceutical Company Method of purifying Factor VIII:C
AT391808B (de) * 1986-11-03 1990-12-10 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion
ATE112287T1 (de) * 1987-12-21 1994-10-15 Miles Inc Faktor viii- gelfiltration.
WO1989009784A1 (en) * 1988-04-08 1989-10-19 Commonwealth Serum Laboratories Commission Production of heat-stable factor viii concentrate
ATE90875T1 (de) * 1989-05-24 1993-07-15 Miles Inc Gelfiltration von waermebehandeltem faktor viii.

Also Published As

Publication number Publication date
HU9201551D0 (en) 1992-08-28
IE904022A1 (en) 1991-05-22
NO921839D0 (no) 1992-05-08
ES2068404T3 (es) 1995-04-16
DE69017050D1 (de) 1995-03-23
HU214905B (hu) 1998-07-28
PL164894B1 (pl) 1994-10-31
ZA908599B (en) 1991-07-31
IL96277A (en) 1995-07-31
ATE118508T1 (de) 1995-03-15
DK162233B (da) 1991-09-30
CA2073012A1 (en) 1991-05-10
SK278640B6 (en) 1997-12-10
BG61231B1 (en) 1997-03-31
YU210590A (sh) 1993-05-28
DK562189A (da) 1991-05-10
WO1991007438A1 (en) 1991-05-30
UA29421C2 (uk) 2000-11-15
DK162233C (da) 1992-03-16
FI922105A0 (fi) 1992-05-08
YU47524B (sh) 1995-10-03
PL287703A1 (en) 1991-12-02
CN1051732A (zh) 1991-05-29
PT95830A (pt) 1991-09-30
DK562189D0 (da) 1989-11-09
AU631471B2 (en) 1992-11-26
FI922105L (fi) 1992-05-08
IL96277A0 (en) 1991-08-16
CN1044121C (zh) 1999-07-14
HUT60511A (en) 1992-09-28
NZ236004A (en) 1991-11-26
SK537190A3 (en) 1997-12-10
JP2509407B2 (ja) 1996-06-19
NO180741B (no) 1997-03-03
BG96316A (bg) 1993-12-24
FI103510B1 (fi) 1999-07-15
DE69017050T2 (de) 1995-06-14
CZ537190A3 (cs) 1998-05-13
AU6747090A (en) 1991-06-13
EP0524172B1 (en) 1995-02-15
FI103510B (fi) 1999-07-15
JPH05501557A (ja) 1993-03-25
US5245014A (en) 1993-09-14
PT95830B (pt) 1997-11-28
CA2073012C (en) 1996-03-19
EP0524172A1 (en) 1993-01-27
IE66836B1 (en) 1996-02-07
RU2055593C1 (ru) 1996-03-10
NO921839L (no) 1992-07-08

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