NO20002540L - Isolering av nukleinsyrer - Google Patents

Isolering av nukleinsyrer

Info

Publication number
NO20002540L
NO20002540L NO20002540A NO20002540A NO20002540L NO 20002540 L NO20002540 L NO 20002540L NO 20002540 A NO20002540 A NO 20002540A NO 20002540 A NO20002540 A NO 20002540A NO 20002540 L NO20002540 L NO 20002540L
Authority
NO
Norway
Prior art keywords
nucleic acids
beads
isolation
solid phase
activated
Prior art date
Application number
NO20002540A
Other languages
English (en)
Other versions
NO315323B1 (no
NO20002540D0 (no
Inventor
Matthew John Baker
Original Assignee
Dna Research Instr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26312726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20002540(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9725839.6A external-priority patent/GB9725839D0/en
Priority claimed from GBGB9815541.9A external-priority patent/GB9815541D0/en
Application filed by Dna Research Instr Ltd filed Critical Dna Research Instr Ltd
Publication of NO20002540D0 publication Critical patent/NO20002540D0/no
Publication of NO20002540L publication Critical patent/NO20002540L/no
Publication of NO315323B1 publication Critical patent/NO315323B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NO20002540A 1997-12-06 2000-05-16 Isolering av nukleinsyrer NO315323B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9725839.6A GB9725839D0 (en) 1997-12-06 1997-12-06 Isolation of nucleic acids
GBGB9815541.9A GB9815541D0 (en) 1998-07-17 1998-07-17 Isolation of nucleic acids
PCT/GB1998/003602 WO1999029703A2 (en) 1997-12-06 1998-12-04 Isolation of nucleic acids

Publications (3)

Publication Number Publication Date
NO20002540D0 NO20002540D0 (no) 2000-05-16
NO20002540L true NO20002540L (no) 2000-07-07
NO315323B1 NO315323B1 (no) 2003-08-18

Family

ID=26312726

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002540A NO315323B1 (no) 1997-12-06 2000-05-16 Isolering av nukleinsyrer

Country Status (15)

Country Link
US (1) US20030130499A1 (no)
EP (2) EP1036082B1 (no)
JP (2) JP2004501054A (no)
KR (2) KR20010032806A (no)
CN (1) CN1230440C (no)
AT (2) ATE386044T1 (no)
AU (1) AU755342B2 (no)
BR (1) BR9815569A (no)
CA (1) CA2318306A1 (no)
DE (2) DE69839133T2 (no)
DK (1) DK1036082T3 (no)
ES (2) ES2301581T3 (no)
NO (1) NO315323B1 (no)
PT (1) PT1036082E (no)
WO (1) WO1999029703A2 (no)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
US6914137B2 (en) * 1997-12-06 2005-07-05 Dna Research Innovations Limited Isolation of nucleic acids
EP1171584A1 (en) * 1999-04-21 2002-01-16 Annovis, Inc. Magnetic dna extraction kit for plants
US6383783B1 (en) * 1999-09-21 2002-05-07 3M Innovative Properties Company Nucleic acid isolation by adhering to hydrophobic solid phase and removing with nonionic surfactant
SE9904539D0 (sv) * 1999-12-10 1999-12-10 Alphahelix Ab Method and device for the handling of samples and reagents
JP2001221721A (ja) * 2000-02-09 2001-08-17 Sapporo Imuno Diagnostic Laboratory:Kk 乾燥濾紙便による遺伝子診断
DE10006590B4 (de) * 2000-02-11 2007-10-18 Qiagen North American Holdings, Inc. Verwendung funktionalisierter Membranen bzw. Matrizes zur Aufreinigung von Nukleinsäuren sowie entsprechende Verfahren
EP1349951A4 (en) * 2001-01-09 2005-08-24 Whitehead Biomedical Inst METHODS AND REAGENTS FOR ISOLATING NUCLEIC ACIDS
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
AU2003202026A1 (en) 2002-01-16 2003-09-02 Dynal Biotech Asa Method for isolating nucleic acids and protein from a single sample
GB0212826D0 (en) 2002-05-31 2002-07-10 Dna Res Innovations Ltd Materials and methods relating to polyions and substance delivery
GB0212825D0 (en) * 2002-05-31 2002-07-10 Dna Res Innovations Ltd Methods compositions and kits for cell separation
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040197780A1 (en) * 2003-04-02 2004-10-07 Agencourt Bioscience Corporation Method for isolating nucleic acids
CN100395257C (zh) * 2003-05-08 2008-06-18 慈溪市中鼎生物技术有限公司 钾离子酸性水溶液和利用这种溶液的dna提取方法和试剂盒
JP4996248B2 (ja) 2003-07-31 2012-08-08 ハンディーラブ インコーポレイテッド 粒子含有サンプルの処理
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
EP2345739B8 (en) * 2004-05-03 2016-12-07 Handylab, Inc. A microfluidic device for processing polynucleotide-containing samples
CA2566866A1 (en) * 2004-05-11 2006-03-09 Wyeth Novel polynucleotides related to oligonucleotide arrays to monitor gene expression
US20060024712A1 (en) * 2004-06-25 2006-02-02 Invitrogen Corporation Separation of nucleic acid
EP1778877B1 (en) 2004-07-28 2009-10-21 Canon U.S. Life Sciences, Inc. Methods for monitoring genomic dna of organisms
JP2008510456A (ja) * 2004-07-30 2008-04-10 アジェンコート バイオサイエンス コーポレーション 多官能基コート化固相担体を用いる核酸の単離方法
JP5053089B2 (ja) * 2004-08-03 2012-10-17 ベクトン・ディキンソン・アンド・カンパニー 化合物の直接単離および多成分サンプルの分別のための磁性材料の使用
KR100647306B1 (ko) * 2004-12-23 2006-11-23 삼성전자주식회사 아미노기와 카르복실기를 포함하고 제1 ｐＨ에서 양전하를띠는 물질을 이용하여 핵산을 분리하는 방법
US7964380B2 (en) 2005-01-21 2011-06-21 Argylia Technologies Nanoparticles for manipulation of biopolymers and methods of thereof
US20060166223A1 (en) * 2005-01-26 2006-07-27 Reed Michael W DNA purification and analysis on nanoengineered surfaces
KR100647315B1 (ko) * 2005-02-02 2006-11-23 삼성전자주식회사 실란화된 고상 물질을 이용한 핵산의 분리 및 증폭 방법
KR101544351B1 (ko) * 2005-02-18 2015-08-13 캐논 유.에스. 라이프 사이언시즈, 인크. 유기체의 게놈 ｄｎａ를 확인하기 위한 장치 및 방법
US20060234251A1 (en) * 2005-04-19 2006-10-19 Lumigen, Inc. Methods of enhancing isolation of RNA from biological samples
KR100668337B1 (ko) 2005-05-21 2007-01-12 삼성전자주식회사 단백질에 비하여 핵산에 대한 결합력이 선택적으로 높은ｐＨ 의존성 이온 교환물질, 그가 고정화되어 있는 고체기판, 및 상기 물질 및 고체 기판을 이용하여 핵산을분리하는 방법
CN101300352B (zh) * 2005-09-01 2013-03-20 佳能美国生命科学公司 检测、分析和鉴定基因组dna的方法和分子诊断装置
GB0522193D0 (en) * 2005-10-31 2005-12-07 Axis Shield Asa Method
JP4871881B2 (ja) * 2005-12-05 2012-02-08 ユニバーサル・バイオ・リサーチ株式会社 ｃＲＮＡの調製方法
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2007112114A2 (en) 2006-03-24 2007-10-04 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
KR100785010B1 (ko) * 2006-04-06 2007-12-11 삼성전자주식회사 수소 결합을 이용하여 고체 지지체의 친수성 표면 상에서핵산 정제 방법 및 장치
EP2423684A3 (en) 2006-04-21 2012-06-27 Wyeth LLC Differential expression profiling analysis of cell culture phenotypes and the uses thereof
US8163535B2 (en) 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
EP2041318A2 (en) 2006-06-26 2009-04-01 Blood Cell Storage, Inc. Device and method for extraction and analysis of nucleic acids from biological samples
KR100813264B1 (ko) * 2006-08-21 2008-03-13 삼성전자주식회사 비평면 형상의 고체 지지체를 이용하여 미생물로부터핵산을 증폭하는 방법
US20080070282A1 (en) 2006-08-21 2008-03-20 Samsung Electronics Co., Ltd. Method and device for obtaining or amplifying nucleic acid from a cell using a nonplanar solid substrate
KR100813265B1 (ko) * 2006-08-21 2008-03-13 삼성전자주식회사 비평면 형상의 고체 지지체를 이용하여 미생물로부터핵산을 증폭하는 방법
US8158411B2 (en) 2006-08-21 2012-04-17 Samsung Electronics Co., Ltd. Method of separating microorganism using nonplanar solid substrate and device for separating microorganism using the same
KR100837401B1 (ko) * 2006-08-21 2008-06-12 삼성전자주식회사 비평면 형상의 고체 지지체를 이용하여 미생물로부터핵산을 분리하는 방법,상기 분리된 핵산을 주형으로 하여핵산을 증폭하는 방법 및 상기 고체 지지체를 포함하는핵산 분리 및 증폭 장치
WO2008035991A2 (en) * 2006-09-19 2008-03-27 Michael Ronald Cook A nucleic acid extraction method
GB2445441B (en) * 2006-09-26 2010-06-30 Ge Healthcare Bio Sciences Nucleic acid purification method
US8709787B2 (en) * 2006-11-14 2014-04-29 Handylab, Inc. Microfluidic cartridge and method of using same
US8999636B2 (en) * 2007-01-08 2015-04-07 Toxic Report Llc Reaction chamber
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
CA2629589C (en) * 2007-04-20 2016-03-29 F.Hoffmann-La Roche Ag Isolation and purification of nucleic acid molecules with a solid phase
WO2008157299A2 (en) * 2007-06-15 2008-12-24 Wyeth Differential expression profiling analysis of cell culture phenotypes and uses thereof
WO2009009127A2 (en) * 2007-07-12 2009-01-15 U.S. Genomics, Inc. Method and system for transferring and/or concentrating a sample
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
WO2009012185A1 (en) 2007-07-13 2009-01-22 Handylab, Inc. Polynucleotide capture materials, and methods of using same
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US10125388B2 (en) 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
US20090186358A1 (en) * 2007-12-21 2009-07-23 Wyeth Pathway Analysis of Cell Culture Phenotypes and Uses Thereof
GB0814570D0 (en) 2008-08-08 2008-09-17 Diagnostics For The Real World Isolation of nucleic acid
KR101015502B1 (ko) * 2008-09-09 2011-02-22 삼성전자주식회사 제1 ｐＨ에서 양전하 및 제2 ｐＨ에서 음전하를 띠는 화합물 및 그를 이용하여 핵산을 분리하는 방법
US8283165B2 (en) 2008-09-12 2012-10-09 Genvault Corporation Matrices and media for storage and stabilization of biomolecules
US8361716B2 (en) * 2008-10-03 2013-01-29 Pathogenetix, Inc. Focusing chamber
US20100204462A1 (en) 2008-10-13 2010-08-12 Thomas Walter Pipette tip with separation material
DE102008063003A1 (de) 2008-12-23 2010-06-24 Qiagen Gmbh Nukleinsäureaufreinigungsverfahren
DE102008063001A1 (de) 2008-12-23 2010-06-24 Qiagen Gmbh Nukleinsäureaufreinigungsverfahren
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
US9415392B2 (en) 2009-03-24 2016-08-16 The University Of Chicago Slip chip device and methods
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
EP2256195A1 (de) 2009-05-12 2010-12-01 Qiagen GmbH Nukleinsäureaufreinigungsverfahren
JP2013505018A (ja) 2009-09-21 2013-02-14 アコーニ バイオシステムズ 磁気溶解方法及び装置
CN102753705A (zh) * 2009-12-14 2012-10-24 B·吴 分离核酸物质的方法和材料
KR101878749B1 (ko) 2010-03-05 2018-07-17 삼성전자주식회사 표적 세포의 분리 방법 및 키트
EP2752670A2 (en) 2010-07-23 2014-07-09 Beckman Coulter, Inc. System or method of including analytical units
AU2012242510B2 (en) 2011-04-15 2015-05-14 Becton, Dickinson And Company Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
EP2729570B1 (en) * 2011-07-04 2017-11-22 Qiagen GmbH Reagent usable for the isolation and/or purification of nucleic acids
CN113388605A (zh) 2011-09-26 2021-09-14 凯杰有限公司 用于分离细胞外核酸的快速方法
JP6117217B2 (ja) 2011-09-30 2017-04-19 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ ユニット化された試薬ストリップ
US9340828B2 (en) 2011-10-27 2016-05-17 Ge Healthcare Bio-Sciences Ab Purification of nucleic acid
EP2773892B1 (en) 2011-11-04 2020-10-07 Handylab, Inc. Polynucleotide sample preparation device
EP2776846B1 (en) 2011-11-07 2019-08-21 Beckman Coulter, Inc. Aliquotter system and workflow
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
CN104053997B (zh) 2011-11-07 2016-12-21 贝克曼考尔特公司 用于处理样本的系统和方法
US9046506B2 (en) 2011-11-07 2015-06-02 Beckman Coulter, Inc. Specimen container detection
BR112014011046A2 (pt) 2011-11-07 2017-06-13 Beckman Coulter, Inc. fluxo de trabalho e sistema de centrífuga
ES2844324T3 (es) 2011-11-07 2021-07-21 Beckman Coulter Inc Brazo robótico
ES2978107T3 (es) 2012-02-03 2024-09-05 Becton Dickinson Co Archivos externos para distribución de pruebas de diagnóstico molecular y determinación de compatibilidad entre pruebas
US8685708B2 (en) 2012-04-18 2014-04-01 Pathogenetix, Inc. Device for preparing a sample
WO2013159116A1 (en) 2012-04-20 2013-10-24 University Of Chicago Fluidic devices for biospecimen preservation
JP6196661B2 (ja) 2012-04-20 2017-09-13 スリップチップ， エルエルシー サンプル調製または自律分析のための流体デバイスおよびシステム
US9803237B2 (en) 2012-04-24 2017-10-31 California Institute Of Technology Slip-induced compartmentalization
JP6170154B2 (ja) 2012-08-28 2017-07-26 バイオキューブシステム インコーポレイテッド 生物学的試料から核酸増幅反応用生物学的分子を迅速に分離するための多孔性固体相及びその用途
US9719082B2 (en) * 2013-10-31 2017-08-01 General Electric Company Substrates and associated methods for elution of nucleic acids
WO2015199423A1 (ko) * 2014-06-24 2015-12-30 (주)바이오니아 자성 입자를 이용한 핵산 분리 방법
CN104513819B (zh) * 2014-12-17 2020-05-05 吉林大学 一种选择性提取dna的方法
EP3307886B1 (en) 2015-06-10 2021-03-24 Qiagen GmbH Method for isolating extracellular nucleic acids using anion exchange particles
KR101696549B1 (ko) * 2015-07-31 2017-01-13 전북대학교산학협력단 수소이온농도 대응 검체 스왑 장치
KR102190922B1 (ko) * 2015-09-01 2020-12-14 삼성전자주식회사 핵산 분리 방법
WO2017162518A1 (en) 2016-03-19 2017-09-28 Qiagen Gmbh Stabilization of rna
US11161107B2 (en) 2016-05-25 2021-11-02 Integrated Micro-Chromatography Systems, Inc. Dispersive pipette extraction system for purification of large biomolecules
CN106520522A (zh) * 2016-12-06 2017-03-22 厦门华厦学院 一种dna萃取装置及方法
EP3502274A1 (de) * 2017-12-22 2019-06-26 Attomol GmbH Probenträger und verfahren zu dessen herstellung
CN108660074B (zh) * 2018-05-28 2022-04-29 嘉兴市艾科诺生物科技有限公司 核酸提取pcr扩增检测一体化解决方案
EP3916397B1 (en) 2019-01-25 2023-08-30 Sekisui Chemical Co., Ltd. Method for isolating nucleic acid, nucleic acid isolation kit, and inspection chip
JP2020124129A (ja) * 2019-02-01 2020-08-20 積水化学工業株式会社 核酸の単離方法及び核酸単離用デバイス
CN110129314B (zh) * 2019-04-24 2021-04-13 合肥欧创基因生物科技有限公司 一种氨基酸缓冲液及血浆游离dna提取试剂盒
CN114845957A (zh) * 2019-09-18 2022-08-02 南科征途有限公司 用于按尺寸富集和分离核酸的设备系统和方法
US20230028205A1 (en) 2019-12-16 2023-01-26 Qiagen Gmbh Enrichment method
US20240287498A1 (en) 2021-06-17 2024-08-29 Qiagen Gmbh Method for isolating non-vesicular mirna

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797202A (en) * 1971-08-27 1974-03-19 Gen Electric Microporous/non-porous composite membranes
US4055469A (en) * 1976-12-10 1977-10-25 Eastman Kodak Company Purification of microbial enzyme extracts using synthetic polyelectrolytes
US4843012A (en) * 1986-09-17 1989-06-27 Genetics Institute, Inc. Novel composition for nucleic acid purification
DE3639949A1 (de) * 1986-11-22 1988-06-09 Diagen Inst Molekularbio Verfahren zur trennung von langkettigen nukleinsaeuren
US5599667A (en) * 1987-03-02 1997-02-04 Gen-Probe Incorporated Polycationic supports and nucleic acid purification separation and hybridization
US4921805A (en) * 1987-07-29 1990-05-01 Life Technologies, Inc. Nucleic acid capture method
CA1297432C (en) * 1987-07-29 1992-03-17 Gulilat Gebeyehu Nucleic acid capture reagent
US4908318A (en) * 1987-09-04 1990-03-13 Integrated Genetics, Inc. Nucleic acid extraction methods
US4923978A (en) * 1987-12-28 1990-05-08 E. I. Du Pont De Nemours & Company Process for purifying nucleic acids
US5234809A (en) * 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5334499A (en) * 1989-04-17 1994-08-02 Eastman Kodak Company Methods of extracting, amplifying and detecting a nucleic acid from whole blood or PBMC fraction
US5124444A (en) * 1989-07-24 1992-06-23 Microprobe Corporation Lactam-containing compositions and methods useful for the extraction of nucleic acids
US5128247A (en) * 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
US5433847A (en) * 1989-11-01 1995-07-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Radial flow chromatography
US5641628A (en) * 1989-11-13 1997-06-24 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
IT1240870B (it) * 1990-02-14 1993-12-17 Talent Procedimento per l'estrazione e la purificazione di dna genomico umano
WO1992008133A1 (en) * 1990-10-29 1992-05-14 Dekalb Plant Genetics Isolation of biological materials using magnetic particles
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5204246A (en) * 1990-12-26 1993-04-20 Pioneer Hi-Bred International, Inc. Dna isolation method
US6051380A (en) * 1993-11-01 2000-04-18 Nanogen, Inc. Methods and procedures for molecular biological analysis and diagnostics
US5710028A (en) * 1992-07-02 1998-01-20 Eyal; Nurit Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor
JPH10502052A (ja) * 1994-04-08 1998-02-24 ハイブライドン インコーポレイテッド 陰イオン交換クロマトグラフィーを用いるオリゴデオキシヌクレオチド・ホスホロチエオエートの精製
US5622822A (en) * 1994-09-13 1997-04-22 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using polyethyleneimine and an anionic phosphate ester surfactant and amplification of same
US5582988A (en) * 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5705628A (en) * 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
US5652348A (en) * 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5660984A (en) * 1994-12-09 1997-08-26 Davis; Thomas E. DNA isolating apparatus comprising a non-porous DNA binding, anion exchange resin and methods of use thereof
US5631146A (en) * 1995-01-19 1997-05-20 The General Hospital Corporation DNA aptamers and catalysts that bind adenosine or adenosine-5'-phosphates and methods for isolation thereof
US5612473A (en) * 1996-01-16 1997-03-18 Gull Laboratories Methods, kits and solutions for preparing sample material for nucleic acid amplification
US5981735A (en) * 1996-02-12 1999-11-09 Cobra Therapeutics Limited Method of plasmid DNA production and purification
SE9600590D0 (sv) * 1996-02-19 1996-02-19 Pharmacia Biotech Ab Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris
US5916746A (en) * 1996-05-09 1999-06-29 Kirkegaard & Perry Laboratories, Inc. Formazan-based immunoassay
US5981235A (en) * 1996-07-29 1999-11-09 Promega Corporation Methods for isolating nucleic acids using alkaline protease
JP3793287B2 (ja) * 1996-08-22 2006-07-05 ペンタックス株式会社 プラスミドｄｎａの単離方法
CA2214495C (en) * 1996-09-25 2002-02-05 Daniel L. Woodard Hydrated zirconium silicate composition for purification of nucleic acids
US6060246A (en) * 1996-11-15 2000-05-09 Avi Biopharma, Inc. Reagent and method for isolation and detection of selected nucleic acid sequences
US5770712A (en) * 1997-03-14 1998-06-23 Virginia Tech Intellectual Properties, Inc. Crosslinked hydrogel beads from chitosan
EP0897978A3 (en) * 1997-08-22 2001-10-17 Becton, Dickinson and Company Zirconium oxide and related compounds for purification of nucleic acids
JP4304348B2 (ja) * 1997-09-22 2009-07-29 独立行政法人理化学研究所 Ｄｎａの単離方法
DE19743518A1 (de) * 1997-10-01 1999-04-15 Roche Diagnostics Gmbh Automatisierbare universell anwendbare Probenvorbereitungsmethode
US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US6194562B1 (en) * 1998-04-22 2001-02-27 Promega Corporation Endotoxin reduction in nucleic acid purification
WO1999058664A1 (en) * 1998-05-14 1999-11-18 Whitehead Institute For Biomedical Research Solid phase technique for selectively isolating nucleic acids
EP1147226B1 (en) * 1999-01-27 2013-01-23 Folim G. Halaka Materials and methods for the purification of polyelectrolytes
US6310199B1 (en) * 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
US6270970B1 (en) * 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids

Also Published As

Publication number Publication date
ATE386044T1 (de) 2008-03-15
CA2318306A1 (en) 1999-06-17
CN1281462A (zh) 2001-01-24
EP1036082B1 (en) 2002-05-29
DK1036082T3 (da) 2002-08-12
NO315323B1 (no) 2003-08-18
US20030130499A1 (en) 2003-07-10
EP1234832B1 (en) 2008-02-13
EP1234832A3 (en) 2003-08-13
KR20050088164A (ko) 2005-09-01
DE69805649D1 (de) 2002-07-04
CN1230440C (zh) 2005-12-07
HK1034520A1 (en) 2001-10-26
DE69839133T2 (de) 2009-02-05
NO20002540D0 (no) 2000-05-16
BR9815569A (pt) 2001-10-09
WO1999029703A2 (en) 1999-06-17
ATE218140T1 (de) 2002-06-15
AU1344799A (en) 1999-06-28
JP2004501054A (ja) 2004-01-15
EP1234832A2 (en) 2002-08-28
DE69805649T2 (de) 2002-12-05
KR20010032806A (ko) 2001-04-25
WO1999029703A3 (en) 1999-08-26
ES2301581T3 (es) 2008-07-01
AU755342B2 (en) 2002-12-12
JP2010162037A (ja) 2010-07-29
EP1036082A2 (en) 2000-09-20
DE69839133D1 (de) 2008-03-27
PT1036082E (pt) 2002-10-31
ES2177093T3 (es) 2002-12-01

Similar Documents

Publication Publication Date Title
NO20002540L (no) Isolering av nukleinsyrer
WO2001071732A3 (en) Porous ferro- or ferrimagnetic glass particles for isolating molecules
AU3376897A (en) Microfluidic method for nucleic acid amplification
WO1993015229A3 (en) Amplification of assay reporters by nucleic acid replication
CA2392802A1 (en) Nucleic acid isolation method and kit
EP1905828A3 (en) Optical sorting method
AU2331095A (en) Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
DK97189A (da) Immobiliseringsproces
CA2207608A1 (en) Isolation of nucleic acid
WO2003062462A3 (en) Method for isolating nucleic acids and protein from a single sample
EP1908832A3 (en) A method for increasing the concentration of a nucleic acid molecule
WO2001077383A3 (en) Nucleic acid detection medium
AU5210798A (en) Nucleic acid construct for expressing active substances which can be activated by proteases, and preparation and use
ATE219093T1 (de) Verfahren zur isolierung von anionischen organischen substanzen aus wässrigen systemen mit kationischen polymernanopartikeln
SE434848B (sv) Forfaringssett for framstellning av porosa cellulosaperlor
AU4857700A (en) Method for rapidly detecting and enumerating microorganisms in mammalian cell preparations using atp bioluminescence
WO2000060114A3 (en) Polynucleotide sequencing using a helicase
EP1310793A4 (en) SUBSTRATE ACTIVATION KIT AND METHOD FOR DETECTING DNA OR SIMILAR
EP1231470A4 (en) SUBSTANCES IMMOBILIZATION METHOD
DE68914689D1 (de) Verbesserte zusammensetzung zur isolierung und anreicherung von nukleinsäure und dadurch verbessertes verfahren.
WO2000040757A3 (en) Method of identifying nucleic acids
EP0682121A4 (en) METHOD FOR AMPLIFYING AND DETECTING A NUCLEOTIDE SEQUENCE USING THERMOSTABLE ENZYMES.
WO2003012089A3 (en) Crystal structure of beta-site app cleaving enzyme (bace) and use thereof
WO2000011472A3 (de) Nachweis von zellen mittels spezifischer zellwand-bindender domänen (cbd) von zellwand-bindenden proteinen
AU2002346403A1 (en) Method for selective conjugation of analytes to enzymes without unwanted enzyme-enzyme cross-linking