NO20003399D0 - <Alfa>-amionoamidderivater som er nyttige som smertestillende midler - Google Patents

<Alfa>-amionoamidderivater som er nyttige som smertestillende midler

Info

Publication number: NO20003399D0
Authority: NO; Norway
Prior art keywords: sub; hydrogen; alkyl; integer; present
Prior art date: 1997-12-31

Application number

NO20003399A

Other languages

English (en)

Other versions

NO327453B1 (no

NO20003399L (no

Inventor

Paolo Pevarello

Mario Varasi

Patricia Salvati

Claes Post

Original Assignee

Newron Pharm Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-31

Filing date

2000-06-29

Publication date

2000-06-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10824342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20003399(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-06-29 Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa

2000-06-29 Publication of NO20003399D0 publication Critical patent/NO20003399D0/no

2000-08-02 Publication of NO20003399L publication Critical patent/NO20003399L/no

2009-07-06 Publication of NO327453B1 publication Critical patent/NO327453B1/no

Links

125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
208000000094 Chronic Pain Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
230000001684 chronic effect Effects 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
208000004296 neuralgia Diseases 0.000 abstract 1
208000021722 neuropathic pain Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

NO20003399A 1997-12-31 2000-06-29 Anvendelse av et alfa-amionoamid for fremstilling av et medikament for bruk som et smertestillende middel NO327453B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9727523.4A GB9727523D0 (en)	1997-12-31	1997-12-31	Alpha-aminoamide derivatives useful as analgesic agents
PCT/EP1998/008157 WO1999035125A1 (en)	1997-12-31	1998-12-12	Alpha-aminoamide derivatives useful as analgesic agents

Publications (3)

Publication Number	Publication Date
NO20003399D0 true NO20003399D0 (no)	2000-06-29
NO20003399L NO20003399L (no)	2000-08-02
NO327453B1 NO327453B1 (no)	2009-07-06

Family

ID=10824342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20003399A NO327453B1 (no)	1997-12-31	2000-06-29	Anvendelse av et alfa-amionoamid for fremstilling av et medikament for bruk som et smertestillende middel

Country Status (18)

Country	Link
US (2)	US6306903B1 (no)
EP (1)	EP1045830B1 (no)
JP (1)	JP4410930B2 (no)
KR (1)	KR100525587B1 (no)
AT (1)	ATE238273T1 (no)
BR (1)	BR9814548A (no)
CA (1)	CA2316902C (no)
DE (1)	DE69813896T2 (no)
DK (1)	DK1045830T3 (no)
EA (1)	EA002763B1 (no)
ES (1)	ES2194392T3 (no)
GB (1)	GB9727523D0 (no)
HU (1)	HU228995B1 (no)
IL (2)	IL136734A0 (no)
NO (1)	NO327453B1 (no)
NZ (1)	NZ505440A (no)
PT (1)	PT1045830E (no)
WO (1)	WO1999035125A1 (no)

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ES2352739T3 (es) *	1997-11-21	2011-02-22	Purdue Neuroscience Company	2-aminoacetamidas sustituidas y el uso de las mismas.
AU2002215053A1 (en) *	2000-11-27	2002-06-24	Pharmacia Italia S.P.A.	Phenylacetamido- pyrazole derivatives and their use as antitumor agents
SI1423168T1 (sl) *	2001-09-03	2006-06-30	Newron Pharm Spa	Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba
US6476068B1 (en)	2001-12-06	2002-11-05	Pharmacia Italia, S.P.A.	Platinum derivative pharmaceutical formulations
EP1438956A1 (en) *	2003-01-16	2004-07-21	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful as antimigraine agents
WO2004087125A1 (en) *	2003-04-02	2004-10-14	Ionix Pharmaceuticals Limited	Amino acid derivatives as inhibitors of mammalian sodium channels
AR044007A1 (es)	2003-04-11	2005-08-24	Newron Pharmaceuticals Inc	Metodos para el tratamiento de la enfermedad de parkinson
WO2005000309A2 (en) *	2003-06-27	2005-01-06	Ionix Pharmaceuticals Limited	Chemical compounds
ES2339021T3 (es) *	2003-08-25	2010-05-14	Newron Pharmaceuticals S.P.A.	Derivados de alfa-aminoamida utiles como agentes antiinflamatorios.
EP1524267A1 (en) *	2003-10-15	2005-04-20	Newron Pharmaceuticals S.p.A.	Substituted benzylaminoalkylene heterocycles
EP1533302A1 (en) *	2003-11-21	2005-05-25	Newron Pharmaceuticals S.p.A.	Histidine derivatives
EP1533298A1 (en)	2003-11-21	2005-05-25	Newron Pharmaceuticals S.p.A.	3-aminopyrrolidone derivatives
EP1533295A1 (en) *	2003-11-24	2005-05-25	Newron Pharmaceuticals S.p.A.	Cyclopentyl Derivatives
EP1535908A1 (en) *	2003-11-24	2005-06-01	Newron Pharmaceuticals S.p.A.	N-acyl-N'-benzyl-alkylendiamino drivatives
EP1557166A1 (en) *	2004-01-21	2005-07-27	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
EP1588704A1 (en)	2004-04-22	2005-10-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
US20080096965A1 (en) *	2004-09-10	2008-04-24	Newron Pharmaceuticals S.P.A.	(Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators
ATE472529T1 (de) *	2005-10-10	2010-07-15	Glaxo Group Ltd	Prolinamidderivate als natriumkanalmodulatoren
TW200730494A (en)	2005-10-10	2007-08-16	Glaxo Group Ltd	Novel compounds
TW200728258A (en)	2005-10-10	2007-08-01	Glaxo Group Ltd	Novel compounds
EP1963280B1 (en)	2005-12-22	2015-10-28	Newron Pharmaceuticals S.p.A.	2-phenylethylamino derivatives as calcium and/or sodium channel modulators
EP1870097A1 (en) *	2006-06-15	2007-12-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
DK2474521T3 (en)	2006-06-19	2016-10-31	Newron Pharm Spa	High-purity 2- [4- (3- and 2-fluorobenzyloxy) benzylamino] propanamides for use as pharmaceuticals and pharmaceutical formulations thus
DK2155663T3 (en)	2007-06-15	2018-01-22	Newron Pharm Spa	SUBSTITUTED 2- [2- (PHENYL) ETHYLAMINO] ALKANAMIDE DERIVATIVES AND THEIR USE AS SODIUM AND / OR CALCIUM CHANNEL MODULATORS
KR101593627B1 (ko)	2007-12-11	2016-02-11	뉴론 파마슈티칼즈 에스. 피. 에이.	고순도의 ２［４（３ 또는 ２플루오로벤질옥시）벤질아미노］프로판아미드의 제조방법
EP2314569A1 (en)	2009-10-22	2011-04-27	Merck Patent GmbH	Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
NZ602648A (en)	2010-04-27	2014-10-31	Newron Pharm Spa	Process for the production of ralfinamide methanesulfonate salts or their r-enantiomers
MX2015002954A (es)	2012-09-10	2015-06-05	Hoffmann La Roche	Nuevas 6-aminoacido-heteroarilhidropirimidinas para el tratamiento y profilaxis de la infeccion del virus de la hepatitis b.
WO2015102390A1 (ko) *	2013-12-30	2015-07-09	이화여자대학교 산학협력단	신규한 아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 통증의 예방 또는 치료용 약학적 조성물
ES2912881T3 (es)	2014-12-23	2022-05-30	Convergence Pharmaceuticals	Procedimiento para preparar derivados de alfa-carboxamida pirrolidina
CN107522654B (zh) *	2016-06-21	2020-09-01	中国人民解放军军事医学科学院毒物药物研究所	新的α-氨基酰胺衍生物及其医药用途
CN112153968A (zh)	2017-10-05	2020-12-29	生物基因公司	制备α-羧酰胺吡咯烷衍生物的工艺

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ES2352739T3 (es)	1997-11-21	2011-02-22	Purdue Neuroscience Company	2-aminoacetamidas sustituidas y el uso de las mismas.
GB9727521D0 (en) *	1997-12-31	1998-02-25	Pharmacia & Upjohn Spa	Substituted 2-benzylamino-2-phenyl-acetamide compounds
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SI1423168T1 (sl)	2001-09-03	2006-06-30	Newron Pharm Spa	Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba
EP1438956A1 (en)	2003-01-16	2004-07-21	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful as antimigraine agents
AR044007A1 (es)	2003-04-11	2005-08-24	Newron Pharmaceuticals Inc	Metodos para el tratamiento de la enfermedad de parkinson
EP1588704A1 (en)	2004-04-22	2005-10-26	Newron Pharmaceuticals S.p.A.	Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders

1997
- 1997-12-31 GB GBGB9727523.4A patent/GB9727523D0/en not_active Ceased
1998
- 1998-12-12 DK DK98966617T patent/DK1045830T3/da active
- 1998-12-12 US US09/582,198 patent/US6306903B1/en not_active Ceased
- 1998-12-12 ES ES98966617T patent/ES2194392T3/es not_active Expired - Lifetime
- 1998-12-12 KR KR10-2000-7007229A patent/KR100525587B1/ko not_active Expired - Lifetime
- 1998-12-12 US US11/359,982 patent/USRE40259E1/en not_active Expired - Lifetime
- 1998-12-12 DE DE69813896T patent/DE69813896T2/de not_active Expired - Lifetime
- 1998-12-12 PT PT98966617T patent/PT1045830E/pt unknown
- 1998-12-12 HU HU0100870A patent/HU228995B1/hu unknown
- 1998-12-12 JP JP2000527527A patent/JP4410930B2/ja not_active Expired - Lifetime
- 1998-12-12 EP EP98966617A patent/EP1045830B1/en not_active Expired - Lifetime
- 1998-12-12 NZ NZ505440A patent/NZ505440A/en not_active IP Right Cessation
- 1998-12-12 AT AT98966617T patent/ATE238273T1/de active
- 1998-12-12 BR BR9814548-7A patent/BR9814548A/pt not_active Application Discontinuation
- 1998-12-12 IL IL13673498A patent/IL136734A0/xx active IP Right Grant
- 1998-12-12 WO PCT/EP1998/008157 patent/WO1999035125A1/en not_active Ceased
- 1998-12-12 CA CA002316902A patent/CA2316902C/en not_active Expired - Lifetime
- 1998-12-12 EA EA200000731A patent/EA002763B1/ru not_active IP Right Cessation
2000
- 2000-06-13 IL IL136734A patent/IL136734A/en not_active IP Right Cessation
- 2000-06-29 NO NO20003399A patent/NO327453B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1045830B1 (en)	2003-04-23
NO327453B1 (no)	2009-07-06
EA200000731A1 (ru)	2001-02-26
HU228995B1 (en)	2013-07-29
GB9727523D0 (en)	1998-02-25
HK1028020A1 (en)	2001-02-02
ATE238273T1 (de)	2003-05-15
IL136734A (en)	2007-03-08
JP2002508302A (ja)	2002-03-19
HUP0100870A3 (en)	2002-11-28
DK1045830T3 (da)	2003-08-04
PT1045830E (pt)	2003-08-29
KR20010033706A (ko)	2001-04-25
NO20003399L (no)	2000-08-02
USRE40259E1 (en)	2008-04-22
NZ505440A (en)	2002-02-01
CA2316902C (en)	2006-06-06
EP1045830A1 (en)	2000-10-25
JP4410930B2 (ja)	2010-02-10
ES2194392T3 (es)	2003-11-16
EA002763B1 (ru)	2002-08-29
CA2316902A1 (en)	1999-07-15
DE69813896T2 (de)	2003-11-06
US6306903B1 (en)	2001-10-23
DE69813896D1 (de)	2003-05-28
IL136734A0 (en)	2001-06-14
KR100525587B1 (ko)	2005-11-03
WO1999035125A1 (en)	1999-07-15
BR9814548A (pt)	2000-10-10
HUP0100870A2 (hu)	2001-07-30

Legal Events

Date	Code	Title	Description
2019-01-14	MK1K	Patent expired

Publication	Publication Date	Title
NO20003399L (no)	2000-08-02	<Alfa>-amionoamidderivater som er nyttige som smertestillende midler
CY1111310T1 (el)	2015-08-05	Ενωσεις για την αγωγη μεταβολικων διαταραχων
WO2004073611A3 (en)	2004-11-25	Compounds for the treatment of metabolic disorders
ATE530066T1 (de)	2011-11-15	Verbindungen zur behandlung von stoffwechselstörungen
MY153023A (en)	2014-12-31	Tropane derivatives useful in therapy
ATE526018T1 (de)	2011-10-15	Verbindungen zur behandlung von stoffwechselstörungen
TNSN06439A1 (fr)	2008-02-22	Derives de 2-carbamide -4-phenylthiazole, leur preparation et leur application en therapeutique
UA95613C2 (ru)	2011-08-25	Соединения для лечения расстройсв метаболизма
ATE503746T1 (de)	2011-04-15	Neue imidazolidinderivate
WO2004093806A3 (en)	2005-04-07	Compounds for the treatment of metabolic disorders
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ATE540675T1 (de)	2012-01-15	Verbindungen zur behandlung von stoffwechselstörungen
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