NO20004311L - Farmasøytisk sammensetning av topiramat - Google Patents
Farmasøytisk sammensetning av topiramatInfo
- Publication number
- NO20004311L NO20004311L NO20004311A NO20004311A NO20004311L NO 20004311 L NO20004311 L NO 20004311L NO 20004311 A NO20004311 A NO 20004311A NO 20004311 A NO20004311 A NO 20004311A NO 20004311 L NO20004311 L NO 20004311L
- Authority
- NO
- Norway
- Prior art keywords
- topiramate
- pharmaceutical composition
- patients
- epilepsy
- preparing
- Prior art date
Links
- KJADKKWYZYXHBB-XBWDGYHZSA-N Topiramic acid Chemical group C1O[C@@]2(COS(N)(=O)=O)OC(C)(C)O[C@H]2[C@@H]2OC(C)(C)O[C@@H]21 KJADKKWYZYXHBB-XBWDGYHZSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 229960004394 topiramate Drugs 0.000 title abstract 3
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000009747 swallowing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Oppfinnelsen er rettet mot en farmasøytisk sammensetning av topiramat, et antikonvulsivt middel som er anvendelig for behandling av epilepsi. Mer spesielt tilveiebringer den foreliggende oppfinnelsen en fast doseringsformulering av topiramat som er tilsiktet primært for anvendelse ved pediatriske pasienter eller for pasienter som har vanskeligheter med å svelge tabletter. Fremgangsmåter for fremstilling av den farmasøytiske sammensetningen er også beskrevet.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7677098P | 1998-03-04 | 1998-03-04 | |
| PCT/US1999/004449 WO1999044581A2 (en) | 1998-03-04 | 1999-03-01 | Pharmaceutical composition of topiramate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20004311D0 NO20004311D0 (no) | 2000-08-30 |
| NO20004311L true NO20004311L (no) | 2000-10-25 |
Family
ID=22134079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20004311A NO20004311L (no) | 1998-03-04 | 2000-08-30 | Farmasøytisk sammensetning av topiramat |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | US6696091B2 (no) |
| EP (1) | EP1066027B1 (no) |
| JP (1) | JP2003530295A (no) |
| KR (1) | KR20010041592A (no) |
| CN (1) | CN100364501C (no) |
| AR (3) | AR017984A1 (no) |
| AT (1) | ATE246490T1 (no) |
| AU (1) | AU763643B2 (no) |
| BG (1) | BG64885B1 (no) |
| BR (1) | BR9908488A (no) |
| CA (1) | CA2322644C (no) |
| DE (1) | DE69910186T2 (no) |
| DK (1) | DK1066027T3 (no) |
| EA (1) | EA200000814A1 (no) |
| EE (1) | EE04175B1 (no) |
| ES (1) | ES2204109T3 (no) |
| HR (1) | HRP20000563B1 (no) |
| HU (1) | HUP0301192A3 (no) |
| ID (1) | ID26982A (no) |
| IL (2) | IL138032A0 (no) |
| MY (1) | MY125821A (no) |
| NO (1) | NO20004311L (no) |
| NZ (1) | NZ506532A (no) |
| PL (1) | PL194559B1 (no) |
| PT (1) | PT1066027E (no) |
| SK (1) | SK285440B6 (no) |
| TR (1) | TR200002541T2 (no) |
| TW (1) | TW590778B (no) |
| UA (1) | UA65607C2 (no) |
| WO (1) | WO1999044581A2 (no) |
| ZA (1) | ZA991716B (no) |
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| KR100664612B1 (ko) | 1999-02-17 | 2007-01-04 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 본태성 진전의 치료에 유용한 항경련성 유도체 |
| NZ514811A (en) * | 1999-04-08 | 2005-01-28 | Ortho Mcneil Pharm Inc | Anticonvulsant derivatives useful in reducing blood glucose levels |
| WO2000076493A1 (en) * | 1999-06-14 | 2000-12-21 | Thomas Najarian | Combination therapy for effecting weight loss and treating obesity |
| EP1157682A1 (en) † | 2000-05-25 | 2001-11-28 | Cilag AG | Blister package for topiramate tablets |
| DK1309324T3 (da) | 2000-07-07 | 2006-06-12 | Ortho Mcneil Pharm Inc | Antikonvulsive derivater egnede til behandling og forebyggelse af udvikling af type II diabetes mellitus og syndrom X |
| NZ537490A (en) * | 2000-10-30 | 2006-11-30 | Ortho Mcneil Pharm Inc | Treatment of diabetes and syndrome X using a sulfamate derivate such as topiramate and metformin |
| US7771749B2 (en) | 2001-07-11 | 2010-08-10 | Monsanto Technology Llc | Lignin-based microparticles for the controlled release of agricultural actives |
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-
1999
- 1999-01-03 UA UA2000085074A patent/UA65607C2/uk unknown
- 1999-03-01 MY MYPI99000735A patent/MY125821A/en unknown
- 1999-03-01 DK DK99908594T patent/DK1066027T3/da active
- 1999-03-01 KR KR1020007009784A patent/KR20010041592A/ko not_active Ceased
- 1999-03-01 US US09/259,718 patent/US6696091B2/en not_active Expired - Lifetime
- 1999-03-01 EA EA200000814A patent/EA200000814A1/ru unknown
- 1999-03-01 WO PCT/US1999/004449 patent/WO1999044581A2/en not_active Ceased
- 1999-03-01 PT PT99908594T patent/PT1066027E/pt unknown
- 1999-03-01 CA CA002322644A patent/CA2322644C/en not_active Expired - Lifetime
- 1999-03-01 HR HR20000563A patent/HRP20000563B1/xx not_active IP Right Cessation
- 1999-03-01 ID IDW20001690A patent/ID26982A/id unknown
- 1999-03-01 ES ES99908594T patent/ES2204109T3/es not_active Expired - Lifetime
- 1999-03-01 DE DE69910186T patent/DE69910186T2/de not_active Revoked
- 1999-03-01 TR TR2000/02541T patent/TR200002541T2/xx unknown
- 1999-03-01 EE EEP200000503A patent/EE04175B1/xx unknown
- 1999-03-01 AT AT99908594T patent/ATE246490T1/de active
- 1999-03-01 NZ NZ506532A patent/NZ506532A/en not_active IP Right Cessation
- 1999-03-01 BR BR9908488-0A patent/BR9908488A/pt not_active Application Discontinuation
- 1999-03-01 AU AU27989/99A patent/AU763643B2/en not_active Expired
- 1999-03-01 PL PL99343894A patent/PL194559B1/pl unknown
- 1999-03-01 CN CNB998035890A patent/CN100364501C/zh not_active Expired - Lifetime
- 1999-03-01 IL IL13803299A patent/IL138032A0/xx active IP Right Grant
- 1999-03-01 EP EP99908594A patent/EP1066027B1/en not_active Revoked
- 1999-03-01 HU HU0301192A patent/HUP0301192A3/hu unknown
- 1999-03-01 JP JP2000534184A patent/JP2003530295A/ja active Pending
- 1999-03-01 SK SK1306-2000A patent/SK285440B6/sk not_active IP Right Cessation
- 1999-03-03 AR ARP990100895A patent/AR017984A1/es not_active Application Discontinuation
- 1999-03-03 ZA ZA9901716A patent/ZA991716B/xx unknown
- 1999-03-26 TW TW088103263A patent/TW590778B/zh not_active IP Right Cessation
-
2000
- 2000-08-23 IL IL138032A patent/IL138032A/en not_active IP Right Cessation
- 2000-08-29 BG BG104727A patent/BG64885B1/bg unknown
- 2000-08-30 NO NO20004311A patent/NO20004311L/no unknown
-
2003
- 2003-12-30 US US10/748,764 patent/US7125560B2/en not_active Expired - Lifetime
-
2005
- 2005-03-31 AR ARP050101281A patent/AR048456A2/es not_active Application Discontinuation
- 2005-03-31 AR ARP050101282A patent/AR048457A2/es not_active Application Discontinuation
-
2006
- 2006-08-25 US US11/467,298 patent/US20060286163A1/en not_active Abandoned
-
2007
- 2007-10-30 US US11/927,850 patent/US20080260813A1/en not_active Abandoned
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