NO20004906L - PDE IV-inhiberende pyridinderivater - Google Patents

PDE IV-inhiberende pyridinderivater

Info

Publication number
NO20004906L
NO20004906L NO20004906A NO20004906A NO20004906L NO 20004906 L NO20004906 L NO 20004906L NO 20004906 A NO20004906 A NO 20004906A NO 20004906 A NO20004906 A NO 20004906A NO 20004906 L NO20004906 L NO 20004906L
Authority
NO
Norway
Prior art keywords
pde
pyridine derivatives
inhibiting
inhibiting pyridine
derivatives
Prior art date
Application number
NO20004906A
Other languages
English (en)
Other versions
NO319531B1 (no
NO20004906D0 (no
Inventor
Eddy Jean Edgard Freyne
Gaston Stanislas Marcell Diels
Maria Enc Matesanz-Ballesteros
Adolfo Diaz-Martinez
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20004906D0 publication Critical patent/NO20004906D0/no
Publication of NO20004906L publication Critical patent/NO20004906L/no
Publication of NO319531B1 publication Critical patent/NO319531B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO20004906A 1998-04-01 2000-09-29 PDE IV-inhiberende pyridinderivater, deres fremstilling og anvendelse, samt sammensetninger omfattende dem NO319531B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201020 1998-04-01
PCT/EP1999/002045 WO1999050262A1 (en) 1998-04-01 1999-03-24 Pde iv inhibiting pyridine derivatives

Publications (3)

Publication Number Publication Date
NO20004906D0 NO20004906D0 (no) 2000-09-29
NO20004906L true NO20004906L (no) 2000-11-28
NO319531B1 NO319531B1 (no) 2005-08-29

Family

ID=8233543

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004906A NO319531B1 (no) 1998-04-01 2000-09-29 PDE IV-inhiberende pyridinderivater, deres fremstilling og anvendelse, samt sammensetninger omfattende dem

Country Status (33)

Country Link
US (1) US6656959B1 (no)
EP (1) EP1068194B1 (no)
JP (1) JP4778612B2 (no)
KR (1) KR100596664B1 (no)
CN (1) CN1172930C (no)
AR (1) AR014972A1 (no)
AT (1) ATE253569T1 (no)
AU (1) AU760771B2 (no)
BG (1) BG64705B1 (no)
BR (1) BR9909326A (no)
CA (1) CA2326045C (no)
CZ (1) CZ298747B6 (no)
DE (1) DE69912590T2 (no)
DK (1) DK1068194T3 (no)
EA (1) EA004207B1 (no)
EE (1) EE04718B1 (no)
ES (1) ES2211061T3 (no)
HR (1) HRP20000619B1 (no)
HU (1) HU229412B1 (no)
ID (1) ID27207A (no)
IL (2) IL138745A0 (no)
MY (1) MY124696A (no)
NO (1) NO319531B1 (no)
NZ (1) NZ507022A (no)
PL (1) PL196026B1 (no)
PT (1) PT1068194E (no)
SI (1) SI1068194T1 (no)
SK (1) SK284468B6 (no)
TR (1) TR200002801T2 (no)
TW (1) TWI242558B (no)
UA (1) UA66842C2 (no)
WO (1) WO1999050262A1 (no)
ZA (1) ZA200006190B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6639077B2 (en) 2000-03-23 2003-10-28 Merck Frosst Canada & Co. Tri-aryl-substituted-ethane PDE4 inhibitors
MY123585A (en) 2000-03-23 2006-05-31 Merck Canada Inc Tri-aryl-substituted-ethane pde4 inhibitors.
DE10130397A1 (de) * 2001-06-23 2003-01-09 Bayer Cropscience Gmbh Herbizide substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbzide und Pflanzenwachstumsregulatoren
DE10318610A1 (de) * 2003-04-24 2004-11-11 Elbion Ag 7-Azaindole und deren Verwendung als Therapeutika
JP4185154B2 (ja) 2004-04-30 2008-11-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 中枢神経系障害治療用の置換モルホリン化合物
US7863446B2 (en) 2006-01-19 2011-01-04 Orchid Research Laboratories Limited Heterocycles
JP2009525269A (ja) 2006-01-30 2009-07-09 ユーロ−セルティーク エス．エイ． カルシウムチャネルブロッカーとしての環状尿素化合物
DE602007011793D1 (de) 2006-10-18 2011-02-17 Pfizer Prod Inc Biaryl-ether-harnstoffverbindungen
BRPI0912029A2 (pt) 2008-02-01 2020-06-30 Orchid Research Laboratories Limited novos heterociclos
JOP20190060A1 (ar) 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876657A (en) * 1971-06-03 1975-04-08 Ashland Oil Inc Preparation of 1-substituted-2-imidazolidinones
US4600430A (en) 1985-02-22 1986-07-15 Eli Lilly And Company Pyridinylimidazolidinone compounds
JP3775685B2 (ja) * 1993-07-28 2006-05-17 ローン−プーラン・ロレ・リミテツド Ｐｄｅ▲ｉｖ▼およびｔｎｆ抑制剤としての化合物
GB9401460D0 (en) * 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
AU3272195A (en) * 1994-08-03 1996-03-04 Gics & Vermee, L.P. Ovenable food package
TW375612B (en) * 1995-04-06 1999-12-01 Janssen Pharmaceutica Nv 1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same
TW332201B (en) * 1995-04-06 1998-05-21 Janssen Pharmaceutica Nv 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives
TW424087B (en) 1995-04-06 2001-03-01 Janssen Pharmaceutica Nv 1,3-dihydro-1-(phenylalkenyl)-2H-imidazol-2-one derivatives
AU6526896A (en) * 1995-07-22 1997-02-18 Rhone-Poulenc Rorer Limited Substituted aromatic compounds and their pharmaceutical use
WO1997024122A1 (en) * 1995-12-29 1997-07-10 Smithkline Beecham Corporation Vitronectin receptor antagonists
SK285878B6 (sk) * 1996-10-02 2007-10-04 Janssen Pharmaceutica N. V. Derivát 2-kyaniminoimidazolu, prostriedok obsahujúci tento derivát, spôsob prípravy tohto prostriedku, uvedený derivát na použitie ako liečivo, použitie tohto derivátu na prípravu liečiva a spôsob prípravy tohto derivátu

Also Published As

Publication number Publication date
KR100596664B1 (ko) 2006-07-06
SK13872000A3 (sk) 2001-11-06
ATE253569T1 (de) 2003-11-15
WO1999050262A1 (en) 1999-10-07
HK1033579A1 (en) 2001-09-07
PL196026B1 (pl) 2007-11-30
CN1295571A (zh) 2001-05-16
ID27207A (id) 2001-03-08
EA200001009A1 (ru) 2001-02-26
AU760771B2 (en) 2003-05-22
CA2326045A1 (en) 1999-10-07
HUP0101239A2 (hu) 2002-05-29
IL138745A (en) 2007-06-17
JP2002509927A (ja) 2002-04-02
BG64705B1 (bg) 2005-12-30
DE69912590D1 (de) 2003-12-11
KR20010040681A (ko) 2001-05-15
CZ20003338A3 (cs) 2001-02-14
BR9909326A (pt) 2000-12-12
HUP0101239A3 (en) 2002-09-30
EE200000569A (et) 2002-04-15
AR014972A1 (es) 2001-04-11
ES2211061T3 (es) 2004-07-01
EA004207B1 (ru) 2004-02-26
SI1068194T1 (en) 2004-04-30
ZA200006190B (en) 2001-10-31
CA2326045C (en) 2008-12-09
BG104718A (en) 2001-04-30
NO319531B1 (no) 2005-08-29
DE69912590T2 (de) 2004-09-16
PL343194A1 (en) 2001-07-30
TR200002801T2 (tr) 2000-12-21
EE04718B1 (et) 2006-10-16
NZ507022A (en) 2002-06-28
CZ298747B6 (cs) 2008-01-16
MY124696A (en) 2006-06-30
UA66842C2 (uk) 2004-06-15
NO20004906D0 (no) 2000-09-29
HRP20000619B1 (en) 2004-06-30
SK284468B6 (sk) 2005-04-01
CN1172930C (zh) 2004-10-27
JP4778612B2 (ja) 2011-09-21
HU229412B1 (en) 2013-12-30
PT1068194E (pt) 2004-03-31
US6656959B1 (en) 2003-12-02
EP1068194A1 (en) 2001-01-17
EP1068194B1 (en) 2003-11-05
AU3147499A (en) 1999-10-18
DK1068194T3 (da) 2004-03-15
TWI242558B (en) 2005-11-01
HRP20000619A2 (en) 2001-10-31
IL138745A0 (en) 2001-10-31

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