NO20010603L - 2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister - Google Patents

2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister

Info

Publication number: NO20010603L
Authority: NO; Norway
Prior art keywords: alkyl; orl; aromatic; unsubstituted; piperidylbenzimidazole
Prior art date: 1998-08-06

Application number

NO20010603A

Other languages

English (en)

Norwegian (no)

Other versions

NO20010603D0 (no

Inventor

Fumitaka Ito

Hirohide Noguchi

Hiroshi Kondo

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-06

Filing date

2001-02-05

Publication date

2001-04-05

2001-02-05 Application filed by Pfizer filed Critical Pfizer

2001-02-05 Publication of NO20010603D0 publication Critical patent/NO20010603D0/no

2001-04-05 Publication of NO20010603L publication Critical patent/NO20010603L/no

Links

108010020615 nociceptin receptor Proteins 0.000 title abstract 2
-1 2-substituted-1-piperidylbenzimidazole compounds Chemical class 0.000 title 1
239000000018 receptor agonist Substances 0.000 title 1
229940044601 receptor agonist Drugs 0.000 title 1
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 1
125000006729 (C2-C5) alkenyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
229940035676 analgesics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical group [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Obesity (AREA)
Toxicology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20010603A 1998-08-06 2001-02-05 2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister NO20010603L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IBPCT/IB98/01206		1998-08-06
PCT/IB1999/001239 WO2000008013A2 (en)	1998-08-06	1999-07-05	2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists

Publications (2)

Publication Number	Publication Date
NO20010603D0 NO20010603D0 (no)	2001-02-05
NO20010603L true NO20010603L (no)	2001-04-05

Family

ID=11004738

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20010603A NO20010603L (no)	1998-08-06	2001-02-05	2-substituert-1-piperidylbenzimidazol forbindelser som ORL 1- reseptor agonister

Country Status (44)

Country	Link
US (1)	US6172067B1 (is)
EP (1)	EP1102762B1 (is)
JP (1)	JP3367945B2 (is)
CN (1)	CN1317968A (is)
AP (1)	AP2001002063A0 (is)
AR (1)	AR018686A1 (is)
AT (1)	ATE227716T1 (is)
AU (1)	AU749166B2 (is)
BG (1)	BG105301A (is)
BR (1)	BR9912778A (is)
CA (1)	CA2339621C (is)
CZ (1)	CZ2001397A3 (is)
DE (1)	DE69903953T2 (is)
DK (1)	DK1102762T3 (is)
EA (1)	EA200100104A1 (is)
EE (1)	EE200100075A (is)
ES (1)	ES2185357T3 (is)
GE (1)	GEP20033000B (is)
GT (1)	GT199900125A (is)
HK (1)	HK1040188A1 (is)
HN (1)	HN1999000105A (is)
HR (1)	HRP20010089B1 (is)
HU (1)	HUP0103567A3 (is)
ID (1)	ID27212A (is)
IL (1)	IL141029A0 (is)
IS (1)	IS5812A (is)
MA (1)	MA26659A1 (is)
NO (1)	NO20010603L (is)
NZ (1)	NZ509299A (is)
OA (1)	OA11590A (is)
PA (1)	PA8477701A1 (is)
PE (1)	PE20000868A1 (is)
PL (1)	PL346211A1 (is)
PT (1)	PT1102762E (is)
SI (1)	SI1102762T1 (is)
SK (1)	SK1602001A3 (is)
SV (1)	SV1999000099A (is)
TN (1)	TNSN99142A1 (is)
TR (1)	TR200100403T2 (is)
TW (1)	TW513424B (is)
UY (1)	UY25659A1 (is)
WO (1)	WO2000008013A2 (is)
YU (1)	YU8201A (is)
ZA (1)	ZA200100900B (is)

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DE60023100T2 (de)	2000-01-05	2006-07-06	Pfizer Inc.	Benzimidazol-Verbindungen zur Verwendung als ORL1-Rezeptor-Antagonisten
GB2359078A (en)	2000-02-11	2001-08-15	Astrazeneca Uk Ltd	Pharmaceutically active pyrimidine derivatives
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GB2359551A (en)	2000-02-23	2001-08-29	Astrazeneca Uk Ltd	Pharmaceutically active pyrimidine derivatives
GB0005642D0 (en)	2000-03-10	2000-05-03	Astrazeneca Uk Ltd	Chemical compounds
SE0003828D0 (sv)	2000-10-20	2000-10-20	Astrazeneca Ab	Novel compounds
WO2002040019A1 (en)	2000-11-15	2002-05-23	Banyu Pharmaceutical Co.,Ltd.	Benzimidazole derivatives
GB0104050D0 (en)	2001-02-19	2001-04-04	Astrazeneca Ab	Chemical compounds
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PT1385514E (pt)	2001-04-18	2009-02-04	Euro Celtique Sa	Compostos espiroindeno e espiroindano
KR100855204B1 (ko)	2001-04-18	2008-09-01	유로-셀티크 소시에떼 아노뉨	노시셉틴 유사체
US6872733B2 (en)	2001-04-18	2005-03-29	Euro-Celtique S.A.	Benzimidazolone compounds
KR100628292B1 (ko)	2001-04-18	2006-09-27	유로-셀티크 소시에떼 아노뉨	스파이로파이라졸 화합물
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SE0102716D0 (sv) *	2001-08-14	2001-08-14	Astrazeneca Ab	Novel compounds
SE0103818D0 (sv) *	2001-11-15	2001-11-15	Astrazeneca Ab	Chemical compounds
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JP4056977B2 (ja)	2002-03-29	2008-03-05	田辺三菱製薬株式会社	睡眠障害治療薬
GB0221828D0 (en)	2002-09-20	2002-10-30	Astrazeneca Ab	Novel compound
GB0221829D0 (en) *	2002-09-20	2002-10-30	Astrazeneca Ab	Novel compound
DE10252666A1 (de) *	2002-11-11	2004-08-05	Grünenthal GmbH	N-Piperidyl-cyclohexan-Derivate
DE10252665A1 (de) *	2002-11-11	2004-06-03	Grünenthal GmbH	4-Aminomethyl-1-aryl-cyclohexylamin-Derivate
SE0301369D0 (sv)	2003-05-09	2003-05-09	Astrazeneca Ab	Chemical compounds
GB0315203D0 (en) *	2003-06-28	2003-08-06	Celltech R&D Ltd	Chemical compounds
SA04250305B1 (ar)	2003-09-25	2008-06-02	سولفاي فارماسوتيكالز بي . في	مشتقات بنزيميدازولون cenzimidazolone وكينازولينون quinazolinone كمساعادات على مستقبلات ORL1 البشرية
GB0328243D0 (en)	2003-12-05	2004-01-07	Astrazeneca Ab	Methods
US20050228023A1 (en) *	2003-12-19	2005-10-13	Sri International	Agonist and antagonist ligands of the nociceptin receptor
WO2006038738A1 (ja) *	2004-10-08	2006-04-13	Takeda Pharmaceutical Company Limited	受容体機能調節剤
US7842817B2 (en)	2005-01-11	2010-11-30	Neurosearch A/S	2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
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EP2280008B1 (en)	2007-01-16	2013-05-29	Purdue Pharma L.P.	Heterocyclic-substituted piperidines as orl-1 ligands
TW201322983A (zh)	2007-08-31	2013-06-16	Purdue Pharma Lp	經取代之喹□啉型哌啶化合物及其用途
US8119661B2 (en) *	2007-09-11	2012-02-21	Astrazeneca Ab	Piperidine derivatives and their use as muscarinic receptor modulators
CN102105465B (zh)	2008-07-21	2015-03-11	普渡制药公司	取代的喹喔啉型桥连哌啶化合物及其用途
CN103168032A (zh)	2010-08-05	2013-06-19	安美基公司	抑制间变性淋巴瘤激酶的苯并咪唑和氮杂苯并咪唑化合物
JP6007262B2 (ja)	2012-01-06	2016-10-12	ノーバス・インターナショナル・インコーポレイテッドＮｏｖｕｓＩｎｔｅｒｎａｔｉｏｎａｌ，Ｉｎｃ．	スルホキシドベース界面活性剤
EP2812313A4 (en)	2012-02-09	2015-09-30	Novus Int Inc	FUNCTIONALIZED POLYMERIC COMPOSITIONS
JO3300B1 (ar)	2012-06-06	2018-09-16	Novartis Ag	مركبات وتركيبات لتعديل نشاط egfr
MX2015000395A (es)	2012-07-12	2015-04-10	Novus Int Inc	Composiciones de matriz y capa para proteccion de bioactivos.
US9085561B2 (en) *	2012-07-30	2015-07-21	Purdue Pharma L.P.	Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
US9090618B2 (en)	2012-12-27	2015-07-28	Purdue Pharma L.P.	Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014153529A1 (en)	2013-03-22	2014-09-25	The Scripps Research Institute	Substituted benzimidazoles as nociceptin receptor modulators
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1999
- 1999-06-25 MA MA25646A patent/MA26659A1/fr unknown
- 1999-06-28 TW TW088110899A patent/TW513424B/zh not_active IP Right Cessation
- 1999-07-05 EE EEP200100075A patent/EE200100075A/xx unknown
- 1999-07-05 AT AT99926688T patent/ATE227716T1/de not_active IP Right Cessation
- 1999-07-05 SI SI9930151T patent/SI1102762T1/xx unknown
- 1999-07-05 TN TNTNSN99142A patent/TNSN99142A1/fr unknown
- 1999-07-05 SK SK160-2001A patent/SK1602001A3/sk unknown
- 1999-07-05 JP JP2000563646A patent/JP3367945B2/ja not_active Expired - Fee Related
- 1999-07-05 HU HU0103567A patent/HUP0103567A3/hu unknown
- 1999-07-05 GE GEAP19995740A patent/GEP20033000B/en unknown
- 1999-07-05 YU YU8201A patent/YU8201A/sh unknown
- 1999-07-05 PL PL99346211A patent/PL346211A1/xx not_active Application Discontinuation
- 1999-07-05 DE DE69903953T patent/DE69903953T2/de not_active Expired - Fee Related
- 1999-07-05 ID IDW20010284D patent/ID27212A/id unknown
- 1999-07-05 WO PCT/IB1999/001239 patent/WO2000008013A2/en not_active Ceased
- 1999-07-05 EA EA200100104A patent/EA200100104A1/ru unknown
- 1999-07-05 BR BR9912778-4A patent/BR9912778A/pt not_active Application Discontinuation
- 1999-07-05 AP APAP/P/2001/002063A patent/AP2001002063A0/en unknown
- 1999-07-05 HR HR970081A patent/HRP20010089B1/xx not_active IP Right Cessation
- 1999-07-05 CZ CZ2001397A patent/CZ2001397A3/cs unknown
- 1999-07-05 PT PT99926688T patent/PT1102762E/pt unknown
- 1999-07-05 IL IL14102999A patent/IL141029A0/xx unknown
- 1999-07-05 EP EP99926688A patent/EP1102762B1/en not_active Expired - Lifetime
- 1999-07-05 ES ES99926688T patent/ES2185357T3/es not_active Expired - Lifetime
- 1999-07-05 HK HK02101444.8A patent/HK1040188A1/zh unknown
- 1999-07-05 CN CN99810857A patent/CN1317968A/zh active Pending
- 1999-07-05 CA CA002339621A patent/CA2339621C/en not_active Expired - Fee Related
- 1999-07-05 OA OA1200100031A patent/OA11590A/en unknown
- 1999-07-05 TR TR2001/00403T patent/TR200100403T2/xx unknown
- 1999-07-05 DK DK99926688T patent/DK1102762T3/da active
- 1999-07-05 AU AU43859/99A patent/AU749166B2/en not_active Ceased
- 1999-07-05 NZ NZ509299A patent/NZ509299A/en not_active Application Discontinuation
- 1999-07-05 HN HN1999000105A patent/HN1999000105A/es unknown
- 1999-07-06 AR ARP990103264A patent/AR018686A1/es active IP Right Grant
- 1999-07-15 PE PE1999000717A patent/PE20000868A1/es not_active Application Discontinuation
- 1999-07-16 SV SV1999000099A patent/SV1999000099A/es not_active Application Discontinuation
- 1999-07-16 PA PA19998477701A patent/PA8477701A1/es unknown
- 1999-08-05 US US09/369,208 patent/US6172067B1/en not_active Expired - Fee Related
- 1999-08-06 GT GT199900125A patent/GT199900125A/es unknown
- 1999-08-13 UY UY25659A patent/UY25659A1/es not_active Application Discontinuation
2001
- 2001-01-16 IS IS5812A patent/IS5812A/is unknown
- 2001-02-01 ZA ZA200100900A patent/ZA200100900B/xx unknown
- 2001-02-05 NO NO20010603A patent/NO20010603L/no not_active Application Discontinuation
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Publication number	Publication date
JP2002522431A (ja)	2002-07-23
GEP20033000B (en)	2003-06-25
IL141029A0 (en)	2002-02-10
EE200100075A (et)	2002-06-17
TW513424B (en)	2002-12-11
HN1999000105A (es)	2000-11-11
AU749166B2 (en)	2002-06-20
PE20000868A1 (es)	2000-08-31
AR018686A1 (es)	2001-11-28
ID27212A (id)	2001-03-08
DE69903953T2 (de)	2003-03-27
BG105301A (en)	2001-12-29
SV1999000099A (es)	2000-09-05
WO2000008013A2 (en)	2000-02-17
SK1602001A3 (en)	2002-09-10
CN1317968A (zh)	2001-10-17
SI1102762T1 (en)	2003-04-30
CA2339621C (en)	2005-04-05
US6172067B1 (en)	2001-01-09
DE69903953D1 (de)	2002-12-19
JP3367945B2 (ja)	2003-01-20
PL346211A1 (en)	2002-01-28
GT199900125A (es)	2001-01-27
NZ509299A (en)	2003-05-30
ATE227716T1 (de)	2002-11-15
HUP0103567A2 (hu)	2002-02-28
PA8477701A1 (es)	2000-09-29
ZA200100900B (en)	2002-08-28
YU8201A (sh)	2003-07-07
BR9912778A (pt)	2001-09-25
AU4385999A (en)	2000-02-28
HK1040188A1 (zh)	2002-05-31
HRP20010089A2 (en)	2002-02-28
AP2001002063A0 (en)	2001-03-31
EA200100104A1 (ru)	2001-08-27
EP1102762A2 (en)	2001-05-30
NO20010603D0 (no)	2001-02-05
TR200100403T2 (tr)	2001-07-23
ES2185357T3 (es)	2003-04-16
DK1102762T3 (da)	2002-12-16
EP1102762B1 (en)	2002-11-13
CA2339621A1 (en)	2000-02-17
TNSN99142A1 (fr)	2005-11-10
WO2000008013A3 (en)	2000-03-23
UY25659A1 (es)	2000-02-23
PT1102762E (pt)	2003-02-28
IS5812A (is)	2001-01-16
MA26659A1 (fr)	2004-12-20
HUP0103567A3 (en)	2003-01-28
HRP20010089B1 (en)	2003-04-30
OA11590A (en)	2004-08-18
CZ2001397A3 (cs)	2002-05-15

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2003-09-15	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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