NO20013435L - Fremgangsmate for fremstilling av bisykliske forbindelser og anvendelse av fremgangsmaten til fremstilling av en ICE-inhibitorforbindelse - Google Patents

Fremgangsmate for fremstilling av bisykliske forbindelser og anvendelse av fremgangsmaten til fremstilling av en ICE-inhibitorforbindelse

Info

Publication number: NO20013435L
Authority: NO; Norway
Prior art keywords: preparing; preparation; inhibitor compound; bicyclic compounds; ice inhibitor
Prior art date: 1999-01-12

Application number

NO20013435A

Other languages

English (en)

Other versions

NO328110B1 (no

NO20013435D0 (no

Inventor

Veronique Crocq

Patrick Roussel

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-12

Filing date

2001-07-11

Publication date

2001-08-27

2001-07-11 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2001-07-11 Publication of NO20013435D0 publication Critical patent/NO20013435D0/no

2001-08-27 Publication of NO20013435L publication Critical patent/NO20013435L/no

2009-12-07 Publication of NO328110B1 publication Critical patent/NO328110B1/no

Links

150000001875 compounds Chemical class 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 3
101000828805 Cowpox virus (strain Brighton Red) Serine proteinase inhibitor 2 Proteins 0.000 title 1
125000002619 bicyclic group Chemical group 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
LOGFVTREOLYCPF-KXNHARMFSA-N (2s,3r)-2-[[(2r)-1-[(2s)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoic acid Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)CCCCN LOGFVTREOLYCPF-KXNHARMFSA-N 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
102000003777 Interleukin-1 beta Human genes 0.000 abstract 1
108090000193 Interleukin-1 beta Proteins 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
150000003007 phosphonic acid derivatives Chemical class 0.000 abstract 1
238000007363 ring formation reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO20013435A 1999-01-12 2001-07-11 Fremgangsmate for fremstilling av bisykliske forbindelser og anvendelse av fremgangsmaten til fremstilling av en ICE-inhibitorforbindelse NO328110B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9900227A FR2788276B1 (fr)	1999-01-12	1999-01-12	NOUVEAU PROCEDE DE PREPARATION DE COMPOSES BICYCLIQUES ET L'APPLICATION DE CE PROCEDE COMME ETAPE INTERMEDIAIRE POUR LA PREPARATION D'UN COMPOSE INHIBITEUR DE L'ENZYME DE CONVERSION DE L'INTERLEUKINE 1-BETA (ice)
PCT/FR2000/000041 WO2000042061A1 (fr)	1999-01-12	2000-01-11	Procede de preparation de composes bicycliques et l'application de ce procede pour la preparation d'un compose inhibiteur de ice

Publications (3)

Publication Number	Publication Date
NO20013435D0 NO20013435D0 (no)	2001-07-11
NO20013435L true NO20013435L (no)	2001-08-27
NO328110B1 NO328110B1 (no)	2009-12-07

Family

ID=9540778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20013435A NO328110B1 (no)	1999-01-12	2001-07-11	Fremgangsmate for fremstilling av bisykliske forbindelser og anvendelse av fremgangsmaten til fremstilling av en ICE-inhibitorforbindelse

Country Status (24)

Country	Link
US (1)	US6512111B1 (no)
EP (1)	EP1144436B1 (no)
JP (1)	JP4601826B2 (no)
KR (1)	KR100797349B1 (no)
CN (1)	CN1240710C (no)
AT (1)	ATE263780T1 (no)
AU (1)	AU774752B2 (no)
BR (1)	BR0007810B1 (no)
CA (1)	CA2359964C (no)
DE (1)	DE60009658T2 (no)
DK (1)	DK1144436T3 (no)
ES (1)	ES2215020T3 (no)
FR (1)	FR2788276B1 (no)
HK (1)	HK1045316B (no)
HU (1)	HU230062B1 (no)
IL (2)	IL144227A0 (no)
NO (1)	NO328110B1 (no)
NZ (1)	NZ512908A (no)
PL (1)	PL196993B1 (no)
PT (1)	PT1144436E (no)
SI (1)	SI1144436T1 (no)
TW (1)	TWI222443B (no)
WO (1)	WO2000042061A1 (no)
ZA (1)	ZA200105550B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6703500B2 (en)	1998-08-19	2004-03-09	Vertex Pharmaceuticals, Incorporated	Method of preparing bicyclic intermediates from piperazic acid or an ester thereof useful in the manufacture of caspase inhibitors
US6559304B1 (en)	1998-08-19	2003-05-06	Vertex Pharmaceuticals Incorporated	Method for synthesizing caspase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2128984B (en) *	1982-05-12	1985-05-22	Hoffmann La Roche	Diaza-bicyclic compounds
ZA833214B (en) *	1982-05-12	1983-12-28	Hoffmann La Roche	Bicyclic compounds

1999
- 1999-01-12 FR FR9900227A patent/FR2788276B1/fr not_active Expired - Fee Related
- 1999-12-10 TW TW088121699A patent/TWI222443B/zh not_active IP Right Cessation
2000
- 2000-01-11 PL PL348919A patent/PL196993B1/pl unknown
- 2000-01-11 DE DE60009658T patent/DE60009658T2/de not_active Expired - Lifetime
- 2000-01-11 HK HK02106828.3A patent/HK1045316B/zh not_active IP Right Cessation
- 2000-01-11 SI SI200030348T patent/SI1144436T1/xx unknown
- 2000-01-11 PT PT00900552T patent/PT1144436E/pt unknown
- 2000-01-11 HU HU0202665A patent/HU230062B1/hu not_active IP Right Cessation
- 2000-01-11 NZ NZ512908A patent/NZ512908A/en not_active IP Right Cessation
- 2000-01-11 IL IL14422700A patent/IL144227A0/xx active IP Right Grant
- 2000-01-11 JP JP2000593628A patent/JP4601826B2/ja not_active Expired - Fee Related
- 2000-01-11 EP EP00900552A patent/EP1144436B1/fr not_active Expired - Lifetime
- 2000-01-11 DK DK00900552T patent/DK1144436T3/da active
- 2000-01-11 AU AU30524/00A patent/AU774752B2/en not_active Ceased
- 2000-01-11 CA CA2359964A patent/CA2359964C/fr not_active Expired - Fee Related
- 2000-01-11 US US09/869,950 patent/US6512111B1/en not_active Expired - Lifetime
- 2000-01-11 CN CNB008048320A patent/CN1240710C/zh not_active Expired - Fee Related
- 2000-01-11 ES ES00900552T patent/ES2215020T3/es not_active Expired - Lifetime
- 2000-01-11 WO PCT/FR2000/000041 patent/WO2000042061A1/fr not_active Ceased
- 2000-01-11 AT AT00900552T patent/ATE263780T1/de active
- 2000-01-11 BR BRPI0007810-7A patent/BR0007810B1/pt not_active IP Right Cessation
- 2000-01-11 KR KR1020017008755A patent/KR100797349B1/ko not_active Expired - Fee Related
2001
- 2001-07-05 ZA ZA200105550A patent/ZA200105550B/en unknown
- 2001-07-10 IL IL144227A patent/IL144227A/en not_active IP Right Cessation
- 2001-07-11 NO NO20013435A patent/NO328110B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU774752B2 (en)	2004-07-08
NZ512908A (en)	2003-07-25
TWI222443B (en)	2004-10-21
FR2788276A1 (fr)	2000-07-13
CA2359964C (fr)	2010-04-20
ATE263780T1 (de)	2004-04-15
CN1240710C (zh)	2006-02-08
PL348919A1 (en)	2002-06-17
KR100797349B1 (ko)	2008-01-22
NO328110B1 (no)	2009-12-07
AU3052400A (en)	2000-08-01
HK1045316A1 (en)	2002-11-22
ES2215020T3 (es)	2004-10-01
JP2002534533A (ja)	2002-10-15
PT1144436E (pt)	2004-08-31
PL196993B1 (pl)	2008-02-29
US6512111B1 (en)	2003-01-28
BR0007810B1 (pt)	2011-08-23
DE60009658T2 (de)	2005-03-24
HUP0202665A2 (hu)	2002-12-28
IL144227A (en)	2006-12-31
EP1144436A1 (fr)	2001-10-17
CN1343218A (zh)	2002-04-03
KR20010101468A (ko)	2001-11-14
ZA200105550B (en)	2002-07-25
NO20013435D0 (no)	2001-07-11
DK1144436T3 (da)	2004-08-02
WO2000042061A1 (fr)	2000-07-20
DE60009658D1 (de)	2004-05-13
HU230062B1 (hu)	2015-06-29
HUP0202665A3 (en)	2004-12-28
EP1144436B1 (fr)	2004-04-07
FR2788276B1 (fr)	2001-02-16
IL144227A0 (en)	2002-05-23
JP4601826B2 (ja)	2010-12-22
CA2359964A1 (fr)	2000-07-20
HK1045316B (zh)	2006-09-29
SI1144436T1 (en)	2004-06-30
BR0007810A (pt)	2001-11-06

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Legal Events

Date	Code	Title	Description
2019-08-26	MM1K	Lapsed by not paying the annual fees