NO20030120L - Aminoalkoholderivater - Google Patents
AminoalkoholderivaterInfo
- Publication number
- NO20030120L NO20030120L NO20030120A NO20030120A NO20030120L NO 20030120 L NO20030120 L NO 20030120L NO 20030120 A NO20030120 A NO 20030120A NO 20030120 A NO20030120 A NO 20030120A NO 20030120 L NO20030120 L NO 20030120L
- Authority
- NO
- Norway
- Prior art keywords
- group
- hydrogen atom
- alkylene
- alkylene group
- substituent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000212246 | 2000-07-13 | ||
| JP2000241744 | 2000-08-09 | ||
| JP2000283218 | 2000-09-19 | ||
| PCT/JP2001/005988 WO2002006268A1 (en) | 2000-07-13 | 2001-07-10 | Amino alcohol derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20030120D0 NO20030120D0 (no) | 2003-01-10 |
| NO20030120L true NO20030120L (no) | 2003-03-11 |
Family
ID=27344040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20030120A NO20030120L (no) | 2000-07-13 | 2003-01-10 | Aminoalkoholderivater |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6723745B2 (de) |
| EP (1) | EP1300405B1 (de) |
| KR (1) | KR100812578B1 (de) |
| CN (2) | CN1267429C (de) |
| AT (1) | ATE360011T1 (de) |
| AU (2) | AU6950301A (de) |
| BR (1) | BR0112484A (de) |
| CA (1) | CA2415678A1 (de) |
| CZ (1) | CZ200350A3 (de) |
| DE (1) | DE60127961D1 (de) |
| HU (1) | HUP0301688A3 (de) |
| IL (3) | IL153594A0 (de) |
| MX (1) | MXPA03000397A (de) |
| NO (1) | NO20030120L (de) |
| NZ (2) | NZ533997A (de) |
| PL (1) | PL359411A1 (de) |
| SK (1) | SK152003A3 (de) |
| TW (1) | TWI301833B (de) |
| WO (1) | WO2002006268A1 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7534263B2 (en) | 2001-05-25 | 2009-05-19 | Conformis, Inc. | Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty |
| US8882847B2 (en) | 2001-05-25 | 2014-11-11 | Conformis, Inc. | Patient selectable knee joint arthroplasty devices |
| US7468075B2 (en) | 2001-05-25 | 2008-12-23 | Conformis, Inc. | Methods and compositions for articular repair |
| EP1300405B1 (de) * | 2000-07-13 | 2007-04-18 | Sankyo Company, Limited | Aminoalkoholderivate |
| AU2001296536A1 (en) | 2000-10-03 | 2002-04-15 | University Of Virginian Patent Foundation | Novel lysophosphatidic acid receptor agonists and antagonists |
| US7064217B2 (en) | 2001-01-30 | 2006-06-20 | University Of Virginia Patent Foundation | Agonists and antagonists of sphingosine-1-phosphate receptors |
| MXPA03008755A (es) * | 2001-03-26 | 2004-02-18 | Novartis Ag | Derivados de 2-amino-propanol. |
| DE60328161D1 (de) | 2002-01-11 | 2009-08-13 | Daiichi Sankyo Co Ltd | Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung |
| WO2003062219A1 (en) * | 2002-01-24 | 2003-07-31 | Eli Lilly And Company | Process for preparing an intermediate useful for the asymmetric synthesis of duloxetine |
| RU2358717C2 (ru) * | 2002-05-16 | 2009-06-20 | Новартис Аг | Применение средств, связывающих edg-рецептор, в лечении ракового заболевания |
| NZ560662A (en) | 2002-05-16 | 2009-09-25 | Novartis Ag | Use of EDG receptor binding agents in cancer |
| SE0202280D0 (sv) * | 2002-07-19 | 2002-07-19 | Astrazeneca Ab | Novel compounds |
| SE0202279D0 (sv) * | 2002-07-19 | 2002-07-19 | Astrazeneca Ab | Novel comppounds |
| WO2004026817A1 (ja) | 2002-09-19 | 2004-04-01 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体とその付加塩及び免疫抑制剤 |
| BR0314760A (pt) * | 2002-09-24 | 2005-07-26 | Novartis Ag | Compostos orgânicos |
| US7452911B2 (en) | 2002-10-31 | 2008-11-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
| CA2505371A1 (en) | 2002-11-07 | 2004-05-27 | Conformis, Inc. | Methods for determining meniscal size and shape and for devising treatment |
| BRPI0409250B8 (pt) | 2003-04-08 | 2022-01-18 | Mitsubishi Pharma Corp | Composições farmacêuticas sólidas compreendendo um agonista receptor de s1p e um álcool do açúcar |
| WO2005005383A1 (ja) * | 2003-07-11 | 2005-01-20 | Sankyo Company, Limited | アミノアルコール化合物 |
| WO2005014525A2 (en) * | 2003-08-12 | 2005-02-17 | Mitsubishi Pharma Corporation | Bi-aryl compound having immunosuppressive activity |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| GB0329498D0 (en) | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
| DE102004004719A1 (de) * | 2004-01-29 | 2005-08-18 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Aminoalkoholen |
| WO2005079788A1 (ja) | 2004-02-24 | 2005-09-01 | Sankyo Company, Limited | アミノアルコール化合物 |
| WO2005081954A2 (en) | 2004-02-25 | 2005-09-09 | Wyeth | Inhibitors of protein tyrosine phosphatase 1b |
| KR20070006889A (ko) * | 2004-05-03 | 2007-01-11 | 노파르티스 아게 | S1p 수용체 작용제 및 jak3 키나제 억제제를 포함하는조합물 |
| US7820703B2 (en) | 2004-05-06 | 2010-10-26 | University Of Virginia Patent Foundation | Lysophosphatidic acid receptor selective antagonists |
| US20110104186A1 (en) | 2004-06-24 | 2011-05-05 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| US7781617B2 (en) | 2004-07-16 | 2010-08-24 | Kyorin Pharmaceutical Co., Ltd | Effective use method of medicaments and method of preventing expression of side effect |
| TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
| US20080096972A1 (en) | 2004-07-30 | 2008-04-24 | Thitiwan Buranachokpaisan | Compound formulations of 2-amino-1, 3-propanediol compounds |
| US7119211B2 (en) * | 2004-09-23 | 2006-10-10 | Yamakawa Chemical Industry Co., Ltd. | Process for preparing optically active 3-(methylamino)-1-(2-thienyl) propan-1-ol and intermediates for preparation |
| EP2511262B1 (de) * | 2004-10-12 | 2017-02-01 | Kyorin Pharmaceutical Co., Ltd. | Verfahren zur herstellung von 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorphenyl]ethyl]-1,3-propandiol-hydrochlorid |
| CA2589265A1 (en) | 2004-11-29 | 2006-06-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
| GB0519274D0 (en) | 2005-09-21 | 2005-11-02 | Arakis Ltd | The treatment of neurodegenerative diseases |
| PT1932522E (pt) * | 2005-10-07 | 2012-06-26 | Kyorin Seiyaku Kk | Agente terapêutico para doenças do fígado contendo, como princípio activo, um derivado de 2- amino-1,3-propanodiol |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| UA100666C2 (uk) | 2006-04-11 | 2013-01-25 | Новартіс Аг | Інгібітори нсv/віл та їх застосування |
| GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
| TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
| SG174028A1 (en) * | 2006-08-08 | 2011-09-29 | Kyorin Seiyaku Kk | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
| MY146775A (en) * | 2006-08-08 | 2012-09-28 | Kyorin Seiyaku Kk | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
| PT3103448T (pt) | 2006-09-26 | 2019-07-12 | Novartis Ag | Composições farmacêuticas que compreendem um modulador de s1p |
| TW200906389A (en) * | 2007-05-25 | 2009-02-16 | Daiichi Sankyo Co Ltd | Pharmaceutical composition comprising of therapeutic or prophylactic agents for hepatitis |
| TW200927142A (en) | 2007-10-12 | 2009-07-01 | Novartis Ag | Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators |
| US8476305B2 (en) | 2008-02-07 | 2013-07-02 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient |
| EP2292594A4 (de) * | 2008-05-19 | 2014-10-15 | Kyorin Seiyaku Kk | Verfahren zur herstellung eines optisch aktiven aminoalkoholderivats |
| US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
| US20110182850A1 (en) | 2009-04-10 | 2011-07-28 | Trixi Brandl | Organic compounds and their uses |
| AU2011311880B2 (en) | 2010-10-08 | 2014-07-24 | Novartis Ag | Vitamin E formulations of sulfamide NS3 inhibitors |
| US9447078B2 (en) | 2012-01-20 | 2016-09-20 | Acucela Inc. | Substituted heterocyclic compounds for disease treatment |
| WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2817494A1 (de) * | 1977-05-03 | 1978-11-09 | Continental Pharma | Aminoalkohol-derivat |
| US4638070A (en) * | 1978-12-21 | 1987-01-20 | Continental Pharma | Heterocyclic amino-alcohol derivatives |
| JPS55124742A (en) * | 1979-03-20 | 1980-09-26 | Kyowa Hakko Kogyo Co Ltd | Novel aminoalcohol derivative |
| JPS60132934A (ja) * | 1983-11-21 | 1985-07-16 | Nippon Shinyaku Co Ltd | ブタノ−ル誘導体 |
| GB8405112D0 (en) * | 1984-02-28 | 1984-04-04 | Akzo Nv | Anti-arrhythmic amino-alcohols |
| US5250546A (en) * | 1984-09-28 | 1993-10-05 | Nippon Chemiphar Co., Ltd. | Amino-alcohol derivatives and processes for their preparation |
| FR2585708B1 (fr) * | 1985-07-31 | 1989-07-07 | Sanofi Sa | Derives aminoalcools peptidiques inhibiteurs de la resine et des proteases acides, leur procede de preparation et leur application en therapeutique |
| IL86740A (en) * | 1987-06-30 | 1992-11-15 | Tanabe Seiyaku Co | Thiphene derivatives,their preparation and pharmaceutical compositions containing them |
| JPH02256612A (ja) * | 1988-12-22 | 1990-10-17 | Tanabe Seiyaku Co Ltd | 消化管機能調整剤 |
| JP2747849B2 (ja) * | 1990-08-24 | 1998-05-06 | 大鵬薬品工業株式会社 | 2’―デオキシヌクレオシド類の選択的アシル化方法 |
| CA2058185A1 (en) * | 1990-12-24 | 1992-06-25 | Manfred Schudok | Process for the acylation of alcohols with immobilized enzymes |
| NO179246C (no) * | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| WO1993015405A1 (en) * | 1992-01-29 | 1993-08-05 | Sci-Clone, Inc. | Carcinoma associated antigen (sk1) monoclonal antibodies against sk1, methods of producing these antibodies and use therfor |
| WO1994008943A1 (fr) * | 1992-10-21 | 1994-04-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose 2-amino-1,3-propanediol et immunosuppresseur |
| US5616726A (en) * | 1993-06-29 | 1997-04-01 | Kaneka Corporation | Optically active aminoalcohol derivatives and method of producing same |
| ATE211726T1 (de) * | 1994-08-22 | 2002-01-15 | Welfide Corp | Benzolderivate und deren medizinische verwendung |
| US5948820A (en) * | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
| EP0786012B1 (de) * | 1994-10-12 | 1998-12-23 | E.I. Du Pont De Nemours And Company | Enzymatisches verfahren zur herstellung von chiralen alpha-tertiären carbonsäureestern |
| JPH09124564A (ja) * | 1995-11-06 | 1997-05-13 | Nikko Rika Kk | 光学活性体混合物ならびにその製造方法 |
| NO965193L (no) * | 1995-12-08 | 1997-06-09 | Seikagaku Kogyo Kk Seikagaku C | Aminalkoholderivat og fremgangsmåte for fremstilling derav |
| WO1997045529A1 (de) * | 1996-05-30 | 1997-12-04 | Lonza Ag | Verfahren zur herstellung von aminoalkoholen und derivaten davon |
| USRE39072E1 (en) | 1997-04-04 | 2006-04-18 | Mitsubishi Pharma Corporation | 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same |
| US6214823B1 (en) * | 1997-10-17 | 2001-04-10 | Merck & Co., Inc. | Benzodiazepine derivatives as antiarrhythmic agents |
| EP1300405B1 (de) | 2000-07-13 | 2007-04-18 | Sankyo Company, Limited | Aminoalkoholderivate |
| EP1315735A4 (de) | 2000-08-31 | 2005-04-06 | Merck & Co Inc | Phosphat-derivate als immunoregulatorische verbindungen |
| US20040058894A1 (en) | 2002-01-18 | 2004-03-25 | Doherty George A. | Selective S1P1/Edg1 receptor agonists |
-
2001
- 2001-07-10 EP EP01947965A patent/EP1300405B1/de not_active Expired - Lifetime
- 2001-07-10 HU HU0301688A patent/HUP0301688A3/hu unknown
- 2001-07-10 NZ NZ533997A patent/NZ533997A/en unknown
- 2001-07-10 IL IL15359401A patent/IL153594A0/xx active IP Right Grant
- 2001-07-10 KR KR1020037000413A patent/KR100812578B1/ko not_active Expired - Fee Related
- 2001-07-10 BR BR0112484-6A patent/BR0112484A/pt not_active IP Right Cessation
- 2001-07-10 AU AU6950301A patent/AU6950301A/xx active Pending
- 2001-07-10 AT AT01947965T patent/ATE360011T1/de not_active IP Right Cessation
- 2001-07-10 CN CNB018153402A patent/CN1267429C/zh not_active Expired - Fee Related
- 2001-07-10 DE DE60127961T patent/DE60127961D1/de not_active Expired - Lifetime
- 2001-07-10 CZ CZ200350A patent/CZ200350A3/cs unknown
- 2001-07-10 PL PL01359411A patent/PL359411A1/xx unknown
- 2001-07-10 CA CA002415678A patent/CA2415678A1/en not_active Abandoned
- 2001-07-10 NZ NZ523554A patent/NZ523554A/xx unknown
- 2001-07-10 SK SK15-2003A patent/SK152003A3/sk not_active Application Discontinuation
- 2001-07-10 AU AU2001269503A patent/AU2001269503B2/en not_active Ceased
- 2001-07-10 CN CNB2005100590917A patent/CN1328387C/zh not_active Expired - Fee Related
- 2001-07-10 WO PCT/JP2001/005988 patent/WO2002006268A1/ja not_active Ceased
- 2001-07-10 MX MXPA03000397A patent/MXPA03000397A/es active IP Right Grant
- 2001-07-12 TW TW090117073A patent/TWI301833B/zh active
-
2002
- 2002-12-22 IL IL153594A patent/IL153594A/en not_active IP Right Cessation
-
2003
- 2003-01-07 US US10/337,702 patent/US6723745B2/en not_active Expired - Fee Related
- 2003-01-10 NO NO20030120A patent/NO20030120L/no not_active Application Discontinuation
- 2003-11-20 US US10/718,858 patent/US6964976B2/en not_active Expired - Fee Related
-
2006
- 2006-03-30 IL IL174664A patent/IL174664A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6950301A (en) | 2002-01-30 |
| EP1300405A1 (de) | 2003-04-09 |
| US20030236297A1 (en) | 2003-12-25 |
| DE60127961D1 (de) | 2007-05-31 |
| IL153594A (en) | 2008-04-13 |
| US20040132784A1 (en) | 2004-07-08 |
| AU2001269503B2 (en) | 2005-02-17 |
| HUP0301688A2 (hu) | 2003-09-29 |
| CZ200350A3 (cs) | 2003-05-14 |
| IL174664A0 (en) | 2006-08-20 |
| KR20030047988A (ko) | 2003-06-18 |
| CN1680563A (zh) | 2005-10-12 |
| CA2415678A1 (en) | 2003-01-10 |
| NO20030120D0 (no) | 2003-01-10 |
| ATE360011T1 (de) | 2007-05-15 |
| CN1267429C (zh) | 2006-08-02 |
| US6964976B2 (en) | 2005-11-15 |
| MXPA03000397A (es) | 2003-05-27 |
| NZ533997A (en) | 2005-11-25 |
| CN1494540A (zh) | 2004-05-05 |
| US6723745B2 (en) | 2004-04-20 |
| PL359411A1 (en) | 2004-08-23 |
| EP1300405B1 (de) | 2007-04-18 |
| BR0112484A (pt) | 2003-09-23 |
| SK152003A3 (en) | 2004-07-07 |
| CN1328387C (zh) | 2007-07-25 |
| EP1300405A4 (de) | 2004-04-21 |
| IL153594A0 (en) | 2003-07-06 |
| HUP0301688A3 (en) | 2006-05-29 |
| WO2002006268A1 (en) | 2002-01-24 |
| NZ523554A (en) | 2004-12-24 |
| HK1051680A1 (en) | 2003-08-15 |
| KR100812578B1 (ko) | 2008-03-13 |
| TWI301833B (en) | 2008-10-11 |
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| FC2A | Withdrawal, rejection or dismissal of laid open patent application |