NO20030926L - Fremgangsmåte for fremstilling av hydrater av olanzapin og deres omdannelsetil krystallinske former av olanzapin - Google Patents
Fremgangsmåte for fremstilling av hydrater av olanzapin og deres omdannelsetil krystallinske former av olanzapinInfo
- Publication number
- NO20030926L NO20030926L NO20030926A NO20030926A NO20030926L NO 20030926 L NO20030926 L NO 20030926L NO 20030926 A NO20030926 A NO 20030926A NO 20030926 A NO20030926 A NO 20030926A NO 20030926 L NO20030926 L NO 20030926L
- Authority
- NO
- Norway
- Prior art keywords
- olanzapine
- hydrates
- conversion
- preparation
- crystalline forms
- Prior art date
Links
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title 2
- 229960005017 olanzapine Drugs 0.000 title 2
- 238000006243 chemical reaction Methods 0.000 title 1
- 150000004677 hydrates Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN709CH2000 | 2000-08-31 | ||
| IN711CH2000 | 2000-08-31 | ||
| PCT/US2001/007258 WO2002018390A1 (en) | 2000-08-31 | 2001-03-07 | Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20030926D0 NO20030926D0 (no) | 2003-02-27 |
| NO20030926L true NO20030926L (no) | 2003-04-24 |
Family
ID=26324874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20030926A NO20030926L (no) | 2000-08-31 | 2003-02-27 | Fremgangsmåte for fremstilling av hydrater av olanzapin og deres omdannelsetil krystallinske former av olanzapin |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1313742A1 (pt) |
| JP (1) | JP2004507548A (pt) |
| AU (1) | AU2001243475A1 (pt) |
| BR (1) | BR0114031A (pt) |
| CA (1) | CA2420987A1 (pt) |
| CZ (1) | CZ2003566A3 (pt) |
| HU (1) | HUP0300875A3 (pt) |
| IL (1) | IL154688A0 (pt) |
| NO (1) | NO20030926L (pt) |
| RU (1) | RU2003108745A (pt) |
| SK (1) | SK2502003A3 (pt) |
| WO (1) | WO2002018390A1 (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002340328A1 (en) * | 2001-10-29 | 2003-05-12 | Janet I. Cord | Olanzapine dihydrate-ii a process for its preparation and use thereof |
| AU2003243153A1 (en) * | 2002-04-23 | 2003-11-10 | Dr. Reddy's Laboratories Limited | Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof |
| AU2002251329A1 (en) * | 2002-04-25 | 2003-11-10 | Generics (Uk) Limited | Novel crystalline forms of celecoxib and other compounds |
| PL196814B1 (pl) * | 2002-05-17 | 2008-02-29 | Inst Farmaceutyczny | Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty |
| US7297789B2 (en) | 2002-05-31 | 2007-11-20 | Sandoz, Inc. | Process of preparation of olanzapine form I |
| SI21270A (sl) | 2002-07-15 | 2004-02-29 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Kristalne oblike olanzapina in postopki za njihovo pripravo |
| PL202856B1 (pl) * | 2002-12-20 | 2009-07-31 | Adamed Spo & Lstrok Ka Z Ogran | Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny |
| US7323459B2 (en) | 2002-12-24 | 2008-01-29 | Teva Pharmaceutical Industries Ltd. | Crystal forms, methods for their preparation and method for preparation of olanzapine |
| DE602004014264D1 (de) | 2003-12-22 | 2008-07-17 | Teva Pharma | Verfahren zur herstellung von olanzapin |
| ATE504588T1 (de) | 2004-01-27 | 2011-04-15 | Synthon Bv | Stabile salze von olanzapin |
| AR047461A1 (es) * | 2004-01-27 | 2006-01-18 | Synthon Bv | Formacion, purificacion y uso de n-formilolanzapina |
| EP1716154A1 (en) * | 2004-02-19 | 2006-11-02 | Neuland Laboratories Ltd | Process for the preparation of olanzapine form 1 useful as antipsychotic drug |
| WO2005107375A2 (en) * | 2004-05-06 | 2005-11-17 | Matrix Laboratories Ltd | Process for the preparation of olanzapine form-i |
| US8044196B2 (en) | 2004-07-14 | 2011-10-25 | Jubilant Organosys Limited | Process for producing pure form of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| EP1781666A1 (en) * | 2004-07-14 | 2007-05-09 | Shasun Chemicals and Drugs Limited | Improved process for making form i of olanzapine. |
| ES2253091B1 (es) | 2004-07-27 | 2007-02-01 | Inke, S.A. | Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo. |
| WO2006025065A1 (en) * | 2004-08-31 | 2006-03-09 | Lee Pharma Private Limited | A process for the preparation of anhydrous olanzopine hydrochloride of form-1 |
| WO2006027800A1 (en) * | 2004-09-06 | 2006-03-16 | Shasun Chemicals And Drugs Limited | A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine |
| PL1838716T3 (pl) * | 2005-01-05 | 2011-09-30 | Lilly Co Eli | Dihydrat embonianu olanzapiny |
| BRPI0608484E2 (pt) * | 2005-03-21 | 2014-10-29 | Reddys Lab Ltd Dr | Processo de preparação da forma i cristalina de olanzapina |
| HUP0501046A2 (en) * | 2005-11-11 | 2007-08-28 | Egis Gyogyszergyar Nyilvanosan | Process for the preparation of olanzapine |
| US7834176B2 (en) | 2006-01-26 | 2010-11-16 | Sandoz Ag | Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E |
| PL381564A1 (pl) | 2007-01-22 | 2008-08-04 | Koźluk Tomasz Nobilus Ent | Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny |
| CA2687143A1 (en) * | 2007-05-15 | 2008-11-20 | Generics [Uk] Limited | Process for the purification of olanzapine |
| EP2292624A1 (en) | 2009-07-20 | 2011-03-09 | LEK Pharmaceuticals d.d. | Process for the purification of olanzapine |
| CN102093386B (zh) * | 2011-01-05 | 2016-06-01 | 浙江华海药业股份有限公司 | 一种制备奥兰扎平晶型ⅱ的方法 |
| JP6008734B2 (ja) * | 2012-12-20 | 2016-10-19 | 株式会社トクヤマ | オランザピンii型結晶の製造方法 |
| PT3466934T (pt) | 2016-05-31 | 2024-04-30 | Taiho Pharmaceutical Co Ltd | Compostos de sulfonamida ou seus sais como inibidores da ribonucleótido-redutase para o tratamento de cancro |
| MX2020005478A (es) | 2017-11-29 | 2020-08-27 | Taiho Pharmaceutical Co Ltd | Compuestos de sulfonamida y usos de los mismos. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9009229D0 (en) | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
| EG23659A (en) * | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| ZA978515B (en) * | 1996-09-23 | 1999-03-23 | Lilly Co Eli | Intermediates and process for preparing olanzapine |
| CZ299247B6 (cs) * | 1996-09-23 | 2008-05-28 | Eli Lilly And Company | Olanzapin dihydrát D |
-
2001
- 2001-03-07 SK SK250-2003A patent/SK2502003A3/sk unknown
- 2001-03-07 JP JP2002523905A patent/JP2004507548A/ja active Pending
- 2001-03-07 CA CA002420987A patent/CA2420987A1/en not_active Abandoned
- 2001-03-07 IL IL15468801A patent/IL154688A0/xx unknown
- 2001-03-07 WO PCT/US2001/007258 patent/WO2002018390A1/en not_active Ceased
- 2001-03-07 EP EP01916449A patent/EP1313742A1/en not_active Withdrawn
- 2001-03-07 AU AU2001243475A patent/AU2001243475A1/en not_active Abandoned
- 2001-03-07 CZ CZ2003566A patent/CZ2003566A3/cs unknown
- 2001-03-07 RU RU2003108745/04A patent/RU2003108745A/ru not_active Application Discontinuation
- 2001-03-07 HU HU0300875A patent/HUP0300875A3/hu unknown
- 2001-03-07 BR BR0114031-0A patent/BR0114031A/pt not_active IP Right Cessation
-
2003
- 2003-02-27 NO NO20030926A patent/NO20030926L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0300875A2 (hu) | 2003-12-29 |
| HUP0300875A3 (en) | 2005-09-28 |
| CA2420987A1 (en) | 2002-03-07 |
| NO20030926D0 (no) | 2003-02-27 |
| RU2003108745A (ru) | 2005-01-10 |
| JP2004507548A (ja) | 2004-03-11 |
| SK2502003A3 (en) | 2004-03-02 |
| BR0114031A (pt) | 2003-09-09 |
| WO2002018390A1 (en) | 2002-03-07 |
| EP1313742A1 (en) | 2003-05-28 |
| CZ2003566A3 (cs) | 2004-01-14 |
| IL154688A0 (en) | 2003-09-17 |
| AU2001243475A1 (en) | 2002-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |