NO20033723L - Vannopplöselig triazolfungicid - Google Patents

Vannopplöselig triazolfungicid

Info

Publication number
NO20033723L
NO20033723L NO20033723A NO20033723A NO20033723L NO 20033723 L NO20033723 L NO 20033723L NO 20033723 A NO20033723 A NO 20033723A NO 20033723 A NO20033723 A NO 20033723A NO 20033723 L NO20033723 L NO 20033723L
Authority
NO
Norway
Prior art keywords
water
triazole fungicide
group
soluble triazole
soluble
Prior art date
Application number
NO20033723A
Other languages
English (en)
Other versions
NO20033723D0 (no
NO326520B1 (no
Inventor
Makoto Mori
Yoshiko Kagoshima
Takuya Uchida
Toshiyuki Konosu
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO20033723D0 publication Critical patent/NO20033723D0/no
Publication of NO20033723L publication Critical patent/NO20033723L/no
Publication of NO326520B1 publication Critical patent/NO326520B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6518—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO20033723A 2001-02-22 2003-08-21 Triazolforbindelser, farmasoytiske preparater som omfatter forbindelsene, forbindelsene for anvendelse som et antifungalt middel, samt anvendelse av forbindelsene ved fremstilling av produkter for behandling av soppinfeksjoner NO326520B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001046890 2001-02-22
PCT/JP2002/001500 WO2002066465A1 (en) 2001-02-22 2002-02-20 Water-soluble triazole fungicide

Publications (3)

Publication Number Publication Date
NO20033723D0 NO20033723D0 (no) 2003-08-21
NO20033723L true NO20033723L (no) 2003-10-21
NO326520B1 NO326520B1 (no) 2008-12-22

Family

ID=18908429

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20033723A NO326520B1 (no) 2001-02-22 2003-08-21 Triazolforbindelser, farmasoytiske preparater som omfatter forbindelsene, forbindelsene for anvendelse som et antifungalt middel, samt anvendelse av forbindelsene ved fremstilling av produkter for behandling av soppinfeksjoner

Country Status (22)

Country Link
US (1) US7230023B2 (no)
EP (1) EP1362856B1 (no)
KR (1) KR100851800B1 (no)
CN (2) CN100430390C (no)
AT (1) ATE407932T1 (no)
AU (1) AU2002234892C9 (no)
BR (1) BR0207534A (no)
CA (1) CA2439001C (no)
CZ (1) CZ20032218A3 (no)
DE (1) DE60228821D1 (no)
ES (1) ES2314028T3 (no)
HU (1) HUP0303249A3 (no)
IL (1) IL157440A0 (no)
MX (1) MXPA03007588A (no)
NO (1) NO326520B1 (no)
NZ (1) NZ527693A (no)
PL (1) PL363523A1 (no)
PT (1) PT1362856E (no)
RU (1) RU2276670C2 (no)
SK (1) SK10592003A3 (no)
WO (1) WO2002066465A1 (no)
ZA (1) ZA200306547B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004026862A1 (ja) * 2002-09-20 2004-04-01 Sankyo Company, Limited 水溶性トリアゾール化合物
DE602005025497D1 (de) 2004-08-05 2011-02-03 Sumitomo Chemical Co Verfahren zur herstellung von halogensubstituiertem benzoldimethanol
KR100738228B1 (ko) 2006-02-22 2007-07-12 한국화학연구원 아졸계 항균제 화합물 및 그의 제조방법
TW200817424A (en) 2006-08-04 2008-04-16 Daiichi Sankyo Co Ltd Benzylphenyl glucopyranoside derivatives
CA2663436A1 (en) 2006-10-04 2008-04-10 Pfizer Products Inc. Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists
WO2010019204A1 (en) * 2008-08-12 2010-02-18 Merck Sharp & Dohme Corp. Antifungal agents
WO2010019206A1 (en) * 2008-08-12 2010-02-18 Merck Sharp & Dohme Corp. Antifungal agents
CN103508981A (zh) * 2012-06-18 2014-01-15 北京美倍他药物研究有限公司 新的哌嗪衍生物及其医药用途
CN107556294A (zh) * 2016-06-30 2018-01-09 陕西合成药业股份有限公司 一种新型抗真菌感染药物及其制备方法和用途
IL293481A (en) * 2019-12-06 2022-08-01 Celgene Corp Processes for the preparation of 2-(4-chlorophenyl)-n-((2-(2,6-dioxypyridin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2104065B (en) * 1981-06-04 1985-11-06 Ciba Geigy Ag Heterocyclyl-substituted mandelic acid compounds and mandelonitriles and their use for combating microorganisms
CS228931B2 (cs) 1981-06-06 1984-05-14 Pfizer Způsob výroby 2-(2,4-difluorfenyl)-l,3-bis(lH-l,2,4-triazol-l-yl)propan- -2-oiu
EP0069442B1 (en) 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
JPS6214766A (ja) 1985-07-11 1987-01-23 Tokyu Foods:Kk 肉そばの製造法
RU2039050C1 (ru) * 1989-09-26 1995-07-09 Такеда Кемикал Индастриз ЛТД Производные 1,2,4-триазола, оптически инертные или имеющие r- или s-конфигурацию c-2 и c-3 асимметричных центров, или их соли, обладающие фунгицидной активностью, и способ их получения
GB9002375D0 (en) 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
IE912990A1 (en) * 1990-08-26 1992-03-11 Sankyo Co Anti-fungal triazole derivatives, their preparation and¹uses
KR920019763A (ko) * 1991-04-26 1992-11-19 모리다 가즈라 아졸 화합물, 그의 제조방법 및 용도
JP3050982B2 (ja) 1991-12-13 2000-06-12 富山化学工業株式会社 新規なトリアゾール誘導体およびその塩
US5622944A (en) 1992-06-12 1997-04-22 Affymax Technologies N.V. Testosterone prodrugs for improved drug delivery
JPH05345768A (ja) 1992-06-13 1993-12-27 Nippon Nohyaku Co Ltd 新規トリアゾール化合物及び該化合物を有効成分とする抗真菌剤
TW297813B (no) * 1993-09-24 1997-02-11 Takeda Pharm Industry Co Ltd
JP3635686B2 (ja) 1994-08-10 2005-04-06 エーザイ株式会社 抗真菌剤及びその製造方法
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
WO1995025107A1 (en) 1994-03-12 1995-09-21 Yuhan Corporation Triazole compounds and processes for the preparation thereof
JP3056412B2 (ja) 1995-02-17 2000-06-26 武田薬品工業株式会社 アゾール化合物およびその用途
DK0841327T3 (da) 1995-04-06 2002-01-21 Sankyo Co Triazolantisvampemiddel
MX9702382A (es) 1995-08-02 1998-02-28 Uriach & Cia Sa J Nuevos derivados de pirimidona con actividad antifungica.
ATE238286T1 (de) 1997-01-17 2003-05-15 Naeja Pharmaceutical Inc Neue triazole als therapeutische mittel gegen pilzinfektionen
JPH10279567A (ja) 1997-02-04 1998-10-20 Sankyo Co Ltd トリアゾール誘導体
JPH1180135A (ja) 1997-07-08 1999-03-26 Sankyo Co Ltd 抗真菌トリアゾール化合物
JP3638438B2 (ja) 1997-12-26 2005-04-13 エスエス製薬株式会社 トリアゾール誘導体またはその塩、その製造方法及び当該化合物を有効成分とする医薬
WO1999045008A1 (en) 1998-03-06 1999-09-10 F. Hoffmann-La Roche Ag 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity
US6265584B1 (en) * 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
AU1177200A (en) 1998-11-10 2000-05-29 Meiji Seika Kaisha Ltd. Novel imidazo(5,1-B)thiazole derivatives and fungicides containing the same as the active ingredient
WO2000030655A1 (en) * 1998-11-20 2000-06-02 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
WO2001005819A1 (en) 1999-07-15 2001-01-25 Kuhnil Pharm. Co., Ltd. Novel water soluble-cyclosporine conjugated compounds
US6362172B2 (en) 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
NZ521241A (en) 2000-03-07 2004-02-27 Ranbaxy Lab Ltd Azole compounds as therapeutic agents for fungal infections
JP2001342187A (ja) 2000-03-27 2001-12-11 Sankyo Co Ltd アミド系トリアゾール化合物
TW591024B (en) 2000-03-27 2004-06-11 Sankyo Lifetech Company Ltd An amide type triazole compound having antifungal activity
US6319933B1 (en) 2000-04-17 2001-11-20 Basilea Pharmaceutica Ag Azole derivatives

Also Published As

Publication number Publication date
DE60228821D1 (de) 2008-10-23
EP1362856A4 (en) 2004-11-24
CN1720913A (zh) 2006-01-18
WO2002066465A1 (en) 2002-08-29
EP1362856B1 (en) 2008-09-10
ATE407932T1 (de) 2008-09-15
AU2002234892B2 (en) 2005-01-06
CN100430390C (zh) 2008-11-05
EP1362856A1 (en) 2003-11-19
AU2002234892C9 (en) 2006-01-05
KR100851800B1 (ko) 2008-08-13
RU2003125879A (ru) 2005-03-20
CZ20032218A3 (cs) 2004-03-17
HUP0303249A2 (hu) 2004-01-28
AU2002234892C1 (en) 2005-06-02
MXPA03007588A (es) 2003-12-04
PL363523A1 (en) 2004-11-29
ZA200306547B (en) 2004-09-01
AU2002234892A1 (en) 2003-02-27
PT1362856E (pt) 2008-12-16
CN100349569C (zh) 2007-11-21
IL157440A0 (en) 2004-03-28
CA2439001A1 (en) 2002-08-29
NO20033723D0 (no) 2003-08-21
ES2314028T3 (es) 2009-03-16
KR20030080030A (ko) 2003-10-10
NO326520B1 (no) 2008-12-22
US20040198790A1 (en) 2004-10-07
RU2276670C2 (ru) 2006-05-20
US7230023B2 (en) 2007-06-12
SK10592003A3 (sk) 2004-05-04
BR0207534A (pt) 2004-07-20
NZ527693A (en) 2004-10-29
CN1503795A (zh) 2004-06-09
HUP0303249A3 (en) 2007-03-28
HK1058037A1 (en) 2004-04-30
CA2439001C (en) 2010-05-04

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