NO20040535L - C-2 metylerte derivater av paclitaxel for anvendelse som antitumor-midler - Google Patents

C-2 metylerte derivater av paclitaxel for anvendelse som antitumor-midler

Info

Publication number: NO20040535L
Authority: NO; Norway
Prior art keywords: sub; paclitaxel; antitumor agents; methylated derivatives; formula
Prior art date: 2001-08-07

Application number

NO20040535A

Other languages

English (en)

Norwegian (no)

Inventor

Ezio Bombardelli

Arturo Battaglia

Gabriele Fontana

Samanta Cimitan

Original Assignee

Lndena Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-07

Filing date

2004-02-05

Publication date

2004-04-26

2004-02-05 Application filed by Lndena Spa filed Critical Lndena Spa

2004-04-26 Publication of NO20040535L publication Critical patent/NO20040535L/no

Links

239000002246 antineoplastic agent Substances 0.000 title 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical class O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000005676 cyclic carbonates Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 t-butoxycarbonyl Chemical group 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Epoxy Compounds (AREA)

NO20040535A 2001-08-07 2004-02-05 C-2 metylerte derivater av paclitaxel for anvendelse som antitumor-midler NO20040535L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2001MI001734A ITMI20011734A1 (it)	2001-08-07	2001-08-07	Derivanti tassanici e procedimenti per la loro preparazione
PCT/EP2002/008185 WO2003013503A1 (en)	2001-08-07	2002-07-23	C-2' methylated derivatives of paclitaxel for use as antitumour agents

Publications (1)

Publication Number	Publication Date
NO20040535L true NO20040535L (no)	2004-04-26

Family

ID=11448252

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20040535A NO20040535L (no)	2001-08-07	2004-02-05	C-2 metylerte derivater av paclitaxel for anvendelse som antitumor-midler

Country Status (20)

Country	Link
US (1)	US7153884B2 (pl)
EP (1)	EP1423108B1 (pl)
KR (1)	KR100894580B1 (pl)
CN (1)	CN100370980C (pl)
AT (1)	ATE363901T1 (pl)
AU (1)	AU2002328942B2 (pl)
BR (1)	BR0211770A (pl)
CA (1)	CA2456523A1 (pl)
DE (1)	DE60220524T2 (pl)
DK (1)	DK1423108T3 (pl)
ES (1)	ES2287310T3 (pl)
HU (1)	HUP0401275A3 (pl)
IL (1)	IL160233A0 (pl)
IT (1)	ITMI20011734A1 (pl)
MX (1)	MXPA04001234A (pl)
NO (1)	NO20040535L (pl)
PL (1)	PL194975B1 (pl)
PT (1)	PT1423108E (pl)
RU (1)	RU2287528C2 (pl)
WO (1)	WO2003013503A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2706881A1 (en) *	2007-11-30	2009-06-11	Brian Z. Ring	Tle3 as a marker for chemotherapy
CN101851231A (zh) *	2010-05-27	2010-10-06	东北林业大学	一种多西紫杉醇新衍生物的合成方法及其在制备抗肿瘤药物中的应用
CN104650012A (zh) *	2013-11-22	2015-05-27	天士力控股集团有限公司	一种紫杉烷类化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2059631C1 (ru) *	1991-11-29	1996-05-10	Дзе Юниверсити оф Канзас	Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
FR2721024B1 (fr) *	1994-06-09	1996-07-12	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

2001
- 2001-08-07 IT IT2001MI001734A patent/ITMI20011734A1/it unknown
2002
- 2002-07-23 IL IL16023302A patent/IL160233A0/xx unknown
- 2002-07-23 AT AT02764753T patent/ATE363901T1/de not_active IP Right Cessation
- 2002-07-23 WO PCT/EP2002/008185 patent/WO2003013503A1/en not_active Ceased
- 2002-07-23 AU AU2002328942A patent/AU2002328942B2/en not_active Ceased
- 2002-07-23 PT PT02764753T patent/PT1423108E/pt unknown
- 2002-07-23 ES ES02764753T patent/ES2287310T3/es not_active Expired - Lifetime
- 2002-07-23 HU HU0401275A patent/HUP0401275A3/hu unknown
- 2002-07-23 DE DE60220524T patent/DE60220524T2/de not_active Expired - Fee Related
- 2002-07-23 EP EP02764753A patent/EP1423108B1/en not_active Expired - Lifetime
- 2002-07-23 RU RU2004103481/04A patent/RU2287528C2/ru not_active IP Right Cessation
- 2002-07-23 CN CNB028153529A patent/CN100370980C/zh not_active Expired - Fee Related
- 2002-07-23 BR BR0211770-3A patent/BR0211770A/pt not_active IP Right Cessation
- 2002-07-23 US US10/485,982 patent/US7153884B2/en not_active Expired - Fee Related
- 2002-07-23 MX MXPA04001234A patent/MXPA04001234A/es active IP Right Grant
- 2002-07-23 DK DK02764753T patent/DK1423108T3/da active
- 2002-07-23 CA CA002456523A patent/CA2456523A1/en not_active Abandoned
- 2002-07-23 PL PL367868A patent/PL194975B1/pl not_active IP Right Cessation
- 2002-07-23 KR KR1020047001736A patent/KR100894580B1/ko not_active Expired - Fee Related
2004
- 2004-02-05 NO NO20040535A patent/NO20040535L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE60220524D1 (de)	2007-07-19
RU2287528C2 (ru)	2006-11-20
ITMI20011734A1 (it)	2003-02-07
DK1423108T3 (da)	2007-10-01
KR20040030926A (ko)	2004-04-09
HK1066483A1 (en)	2005-03-24
DE60220524T2 (de)	2008-02-07
RU2004103481A (ru)	2005-06-10
US7153884B2 (en)	2006-12-26
WO2003013503A1 (en)	2003-02-20
IL160233A0 (en)	2004-07-25
ES2287310T3 (es)	2007-12-16
EP1423108A1 (en)	2004-06-02
PL194975B1 (pl)	2007-07-31
CA2456523A1 (en)	2003-02-20
AU2002328942B2 (en)	2007-08-30
CN100370980C (zh)	2008-02-27
HUP0401275A3 (en)	2007-05-29
KR100894580B1 (ko)	2009-04-24
ATE363901T1 (de)	2007-06-15
BR0211770A (pt)	2004-07-27
US20040242674A1 (en)	2004-12-02
ITMI20011734A0 (it)	2001-08-07
HUP0401275A2 (hu)	2004-10-28
MXPA04001234A (es)	2004-05-27
EP1423108B1 (en)	2007-06-06
CN1538841A (zh)	2004-10-20
PT1423108E (pt)	2007-08-28
PL367868A1 (pl)	2005-03-07

Similar Documents

Publication	Publication Date	Title
DK1585739T3 (da)	2011-06-20	Substituerede arylcyclopropylacetamider som glucokinaseaktivatorer
MXPA06012595A (es)	2007-05-09	Analogos de amino-tetrazoles y metodos de uso.
ATE283253T1 (de)	2004-12-15	Substituierte aminopropoxyarylderivate als lxr agonisten
ATE260275T1 (de)	2004-03-15	Substituierte thien-3-yl- sulfonylamino(thio)carbonyl-triazolin(thi)one
HRP20090195T1 (hr)	2009-05-31	Inhibitori mitotičkih kinezina
BR0207302A (pt)	2004-02-10	Trifluorometilpurinas como inibidores da fosfodiesterase 4
EA200601686A1 (ru)	2007-02-27	Замещенные производные морфолина и тиоморфолина
DK1385515T3 (da)	2008-10-27	Spiropyrazole forbindelser
CY1106247T1 (el)	2011-06-08	Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
MX2009003713A (es)	2009-07-02	Inhibidor de progresion de enfermedad de alzheimer que contiene un compuesto heterociclico con estructura especifica.
EA200600694A1 (ru)	2006-10-27	Дисульфидные, сульфидные, сульфоксидные и сульфоновые производные циклических сахаров и их применение
DE60336735D1 (de)	2011-05-26	Neue biologischaktive molekü le
HRP20080057T3 (en)	2008-02-29	9,10-alpha,alpha-oh-taxane analogs and methods for production thereof
DK1644389T3 (da)	2011-05-09	Pyrinidinforbindelser med phosphonatgrupper som antivirale nukleotidanaloger
NO20061317L (no)	2006-03-23	Imidazopyridinderivater som induserbare NO-syntaseinhibatorer
BR0208812A (pt)	2004-03-09	Derivados fenil heterociclil éter como inibidores de recaptação de serotonina
ATE419242T1 (de)	2009-01-15	Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
ATE239722T1 (de)	2003-05-15	Benzofurylpiperazine als serotonin-agonisten
NO20050871L (no)	2005-02-18	6-amino-1H-indazol- og 4-aminobenzofuranforbindelser som fosfodiesterase 4-inhibitorer
NO20040535L (no)	2004-04-26	C-2 metylerte derivater av paclitaxel for anvendelse som antitumor-midler
MXPA06003345A (es)	2006-06-08	Derivados de aminopiridina como inhibidores de la no-sintasa inducible.
EA200600608A1 (ru)	2006-10-27	Производные имидазопиридина как ингибиторы индуцируемой no-синтазы
ATE401325T1 (de)	2008-08-15	C10-carbamoyloxysubstituierte taxane als antitumormittel
MXPA05012279A (es)	2006-02-10	Derivados de bencil sulfonamida.
SE0402734D0 (sv)	2004-11-10	Antimiicrobial compounds

Legal Events

Date	Code	Title	Description
2010-03-01	FC2A	Withdrawal, rejection or dismissal of laid open patent application