NO20041704L - Substituerte alkylaminopyridazinonderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som inneholder disse - Google Patents

Substituerte alkylaminopyridazinonderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som inneholder disse

Info

Publication number: NO20041704L
Authority: NO; Norway
Prior art keywords: sub; hydrogen; stands; alkyl; carbon atoms
Prior art date: 2001-09-27

Application number

NO20041704A

Other languages

English (en)

Other versions

NO325080B1 (no

Inventor

Aniko Miklosne Kovacs

Istvan Gacsalyi

Jozsef Barkoczy

Janos Wellmann

Laszlo Gabor Harsing

Peter Kotay Nagy

Gyorgy Levay

Andras Egyed

Gyula Simig

Eva Schmidt

Gabor Szenasi

Bernadett Martonne Marko

Csilla Leveleki

Hajnalka Kompagne

Original Assignee

Egyt Gyogyszervegyeszeti Gyar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-27

Filing date

2004-04-26

Publication date

2004-04-26

2004-04-26 Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar

2004-04-26 Publication of NO20041704L publication Critical patent/NO20041704L/no

2008-01-28 Publication of NO325080B1 publication Critical patent/NO325080B1/no

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
125000004432 carbon atom Chemical group C* 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
208000010877 cognitive disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000004193 piperazinyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO20041704A 2001-09-27 2004-04-26 Substituerte alkylaminopyridazinonderivater, fremgangsmater til deres fremstilling, og farmasoytiske sammensetninger som inneholder disse, fremgangsmate til fremstilling av sammensetningen og anvendelse av derivatene til a fremstille farmasoytiske preparater. NO325080B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0103912A HU227237B1 (en)	2001-09-27	2001-09-27	Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them
PCT/HU2002/000096 WO2003027097A1 (en)	2001-09-27	2002-09-26	Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same

Publications (2)

Publication Number	Publication Date
NO20041704L true NO20041704L (no)	2004-04-26
NO325080B1 NO325080B1 (no)	2008-01-28

Family

ID=89979721

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20041551A NO326370B1 (no)	2001-09-27	2004-04-16	Substituerte alkylaminopyridazinonderivater, fremgangsmate til fremstilling derav, anvendelse derav, farmasoytisk sammensetning som inneholder dem og fremgangsmate for fremstilling av sammensetningene
NO20041704A NO325080B1 (no)	2001-09-27	2004-04-26	Substituerte alkylaminopyridazinonderivater, fremgangsmater til deres fremstilling, og farmasoytiske sammensetninger som inneholder disse, fremgangsmate til fremstilling av sammensetningen og anvendelse av derivatene til a fremstille farmasoytiske preparater.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO20041551A NO326370B1 (no)	2001-09-27	2004-04-16	Substituerte alkylaminopyridazinonderivater, fremgangsmate til fremstilling derav, anvendelse derav, farmasoytisk sammensetning som inneholder dem og fremgangsmate for fremstilling av sammensetningene

Country Status (25)

Country	Link
US (2)	US20050043314A1 (no)
EP (2)	EP1430034B1 (no)
JP (2)	JP2005508914A (no)
KR (2)	KR100890667B1 (no)
CN (3)	CN1325489C (no)
AT (2)	ATE288910T1 (no)
AU (2)	AU2002330656B9 (no)
BR (2)	BR0212932A (no)
CA (2)	CA2461510C (no)
CZ (2)	CZ2004532A3 (no)
DE (2)	DE60202970T2 (no)
DK (2)	DK1430034T3 (no)
EA (2)	EA006942B1 (no)
ES (2)	ES2237696T3 (no)
HU (1)	HU227237B1 (no)
MA (2)	MA27068A1 (no)
MX (2)	MXPA04002838A (no)
NO (2)	NO326370B1 (no)
NZ (2)	NZ532103A (no)
PL (2)	PL369107A1 (no)
PT (2)	PT1430047E (no)
SI (2)	SI1430047T1 (no)
SK (2)	SK1902004A3 (no)
WO (2)	WO2003027078A1 (no)
ZA (2)	ZA200402545B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7504395B2 (en) *	2001-07-20	2009-03-17	Psychogenics, Inc.	Treatment for attention-deficit hyperactivity disorder
HU227592B1 (en) *	2002-11-13	2011-09-28	Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag	Use of substituted alkyl-piridazinone derivatives for the treatment of memory decline and learning malfunctions
CL2008000725A1 (es) *	2007-03-15	2008-11-14	Schering Corp	Compuestos derivados de heterociclos aromaticos; composicion farmaceutica; kit farmceuticos; uso de la composicion y de los compuestos como inhibidores de glucano sintasa para el tratamiento o prevencion del crecimiento de patogenos fungicos en planta y para tratar o prevenir infecciones producidas por hongos.
SI3788040T1 (sl) *	2018-04-30	2023-07-31	Ribon Therapeutics Inc.	Piridazinoni kot zaviralci parp7
CN109053693B (zh)	2018-09-20	2021-02-05	顺毅股份有限公司	哒嗪胺类化合物的制备及其应用
US12371421B2 (en)	2019-04-29	2025-07-29	Ribon Therapeutics, Inc.	Solid forms of a PARP7 inhibitor
MX2022005216A (es)	2019-10-30	2022-06-02	Ribon Therapeutics Inc	Piridazinonas como inhibidores de poli(adp-ribosa) polimerasa 7 (parp7).
WO2022188889A1 (zh) *	2021-03-12	2022-09-15	杭州英创医药科技有限公司	作为parp7抑制剂的化合物
CN115490671B (zh) *	2022-10-21	2024-05-14	水木未来(北京)科技有限公司	Parp7抑制剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH557820A (de) *	1970-11-12	1975-01-15	Sandoz Ag	Verfahren zur herstellung von neuen 2-(2-hydroxyalkyl)4,5-dihydro-pyridazin (2h)-3-onen.
IE62890B1 (en) *	1988-12-06	1995-03-08	Hafslund Nycomed Pharma	New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
PL164079B1 (pl) *	1990-06-15	1994-06-30	Akad Medyczna	posób wytwarzania nowych 2-amlnoalkilopochodnych 5-aminometyleno-6-/p-chlorofenylo /-4,5-dihydro-2H- plrydazyn -3-onu
HU209388B (en) *	1990-12-27	1994-05-30	Richter Gedeon Vegyeszet	Process for producing new 3/2h/-pyridazinones and pharmaceutical compositions comprising same
HU214320B (hu) *	1991-12-20	1998-03-02	EGIS Gyógyszergyár Rt.	Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására
HU224067B1 (hu) *	1995-05-29	2005-05-30	Gyógyszerkutató Intézet Kft.	3(2H)-Piridazinon-származékok és e vegyületeket tartalmazó gyógyszerkészítmények
JP2004500314A (ja) *	1998-06-05	2004-01-08	エギシュ　ヂョヂセルヂャール　エルテー	３（２ｈ）−ピリダジノン−４−置換アミノ−５−クロロ−誘導体の製法

2001
- 2001-09-27 HU HU0103912A patent/HU227237B1/hu not_active IP Right Cessation
2002
- 2002-09-26 EA EA200400470A patent/EA006942B1/ru not_active IP Right Cessation
- 2002-09-26 ES ES02767729T patent/ES2237696T3/es not_active Expired - Lifetime
- 2002-09-26 CN CNB028204425A patent/CN1325489C/zh not_active Expired - Fee Related
- 2002-09-26 DK DK02767729T patent/DK1430034T3/da active
- 2002-09-26 CZ CZ2004532A patent/CZ2004532A3/cs unknown
- 2002-09-26 NZ NZ532103A patent/NZ532103A/en unknown
- 2002-09-26 KR KR1020047004606A patent/KR100890667B1/ko not_active Expired - Fee Related
- 2002-09-26 JP JP2003530669A patent/JP2005508914A/ja active Pending
- 2002-09-26 CZ CZ2004528A patent/CZ2004528A3/cs unknown
- 2002-09-26 AT AT02762620T patent/ATE288910T1/de not_active IP Right Cessation
- 2002-09-26 AU AU2002330656A patent/AU2002330656B9/en not_active Ceased
- 2002-09-26 BR BR0212932-9A patent/BR0212932A/pt not_active IP Right Cessation
- 2002-09-26 EP EP02767729A patent/EP1430034B1/en not_active Expired - Lifetime
- 2002-09-26 SK SK1902004A patent/SK1902004A3/sk unknown
- 2002-09-26 BR BR0212839-0A patent/BR0212839A/pt not_active IP Right Cessation
- 2002-09-26 PT PT02762620T patent/PT1430047E/pt unknown
- 2002-09-26 US US10/490,959 patent/US20050043314A1/en not_active Abandoned
- 2002-09-26 CN CNB028189752A patent/CN100368404C/zh not_active Expired - Fee Related
- 2002-09-26 DK DK02762620T patent/DK1430047T3/da active
- 2002-09-26 DE DE60202970T patent/DE60202970T2/de not_active Expired - Lifetime
- 2002-09-26 SI SI200230109T patent/SI1430047T1/xx unknown
- 2002-09-26 DE DE60202969T patent/DE60202969T2/de not_active Expired - Lifetime
- 2002-09-26 WO PCT/HU2002/000097 patent/WO2003027078A1/en not_active Ceased
- 2002-09-26 EP EP02762620A patent/EP1430047B1/en not_active Expired - Lifetime
- 2002-09-26 AT AT02767729T patent/ATE288899T1/de not_active IP Right Cessation
- 2002-09-26 AU AU2002328166A patent/AU2002328166B2/en not_active Ceased
- 2002-09-26 CA CA002461510A patent/CA2461510C/en not_active Expired - Fee Related
- 2002-09-26 JP JP2003530685A patent/JP4472337B2/ja not_active Expired - Lifetime
- 2002-09-26 CA CA002461467A patent/CA2461467A1/en not_active Abandoned
- 2002-09-26 CN CN200710104934XA patent/CN101099740B/zh not_active Expired - Fee Related
- 2002-09-26 ES ES02762620T patent/ES2237690T3/es not_active Expired - Lifetime
- 2002-09-26 PT PT02767729T patent/PT1430034E/pt unknown
- 2002-09-26 SK SK1892004A patent/SK1892004A3/sk unknown
- 2002-09-26 MX MXPA04002838A patent/MXPA04002838A/es active IP Right Grant
- 2002-09-26 SI SI200230107T patent/SI1430034T1/xx unknown
- 2002-09-26 KR KR1020047004607A patent/KR100911069B1/ko not_active Expired - Fee Related
- 2002-09-26 WO PCT/HU2002/000096 patent/WO2003027097A1/en not_active Ceased
- 2002-09-26 MX MXPA04002836A patent/MXPA04002836A/es active IP Right Grant
- 2002-09-26 EA EA200400469A patent/EA006392B1/ru not_active IP Right Cessation
- 2002-09-26 PL PL02369107A patent/PL369107A1/xx not_active IP Right Cessation
- 2002-09-26 NZ NZ532104A patent/NZ532104A/en unknown
- 2002-09-26 US US10/491,151 patent/US6930110B2/en not_active Expired - Fee Related
- 2002-09-26 PL PL02369256A patent/PL369256A1/xx unknown
2004
- 2004-03-24 MA MA27589A patent/MA27068A1/fr unknown
- 2004-03-24 MA MA27588A patent/MA27137A1/fr unknown
- 2004-03-31 ZA ZA200402545A patent/ZA200402545B/en unknown
- 2004-03-31 ZA ZA200402544A patent/ZA200402544B/en unknown
- 2004-04-16 NO NO20041551A patent/NO326370B1/no not_active IP Right Cessation
- 2004-04-26 NO NO20041704A patent/NO325080B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR0212839A (pt)	2004-10-13
DK1430034T3 (da)	2005-05-30
ATE288910T1 (de)	2005-02-15
MA27068A1 (fr)	2004-12-20
HUP0103912A2 (hu)	2003-07-28
PT1430047E (pt)	2005-06-30
HUP0103912A3 (en)	2004-03-01
MXPA04002838A (es)	2004-07-05
EP1430047B1 (en)	2005-02-09
SI1430034T1 (en)	2005-08-31
ZA200402545B (en)	2005-04-26
EP1430047A1 (en)	2004-06-23
ES2237690T3 (es)	2005-08-01
CN101099740B (zh)	2010-09-08
CA2461510A1 (en)	2003-04-03
DE60202969T2 (de)	2006-01-19
WO2003027097A1 (en)	2003-04-03
KR100911069B1 (ko)	2009-08-06
AU2002328166B2 (en)	2008-04-17
AU2002330656B2 (en)	2009-04-09
KR20040039445A (ko)	2004-05-10
PT1430034E (pt)	2005-06-30
JP2005508914A (ja)	2005-04-07
CN1571783A (zh)	2005-01-26
SI1430047T1 (en)	2005-08-31
HU0103912D0 (en)	2001-12-28
JP4472337B2 (ja)	2010-06-02
CA2461510C (en)	2009-07-07
CN100368404C (zh)	2008-02-13
PL369107A1 (en)	2005-04-18
AU2002328166A2 (en)	2003-04-07
CN1558904A (zh)	2004-12-29
HK1069816A1 (en)	2005-06-03
NO326370B1 (no)	2008-11-17
AU2002330656B9 (en)	2009-09-03
CN101099740A (zh)	2008-01-09
DE60202970T2 (de)	2006-02-16
ES2237696T3 (es)	2005-08-01
ATE288899T1 (de)	2005-02-15
NZ532103A (en)	2005-08-26
KR20040039446A (ko)	2004-05-10
US6930110B2 (en)	2005-08-16
DE60202969D1 (de)	2005-03-17
NO20041551L (no)	2004-06-10
PL369256A1 (en)	2005-04-18
JP2005503437A (ja)	2005-02-03
EP1430034A1 (en)	2004-06-23
CZ2004532A3 (cs)	2004-08-18
CN1325489C (zh)	2007-07-11
HU227237B1 (en)	2010-12-28
DE60202970D1 (de)	2005-03-17
CA2461467A1 (en)	2003-04-03
EA200400469A1 (ru)	2004-08-26
MXPA04002836A (es)	2004-07-05
MA27137A1 (fr)	2005-01-03
DK1430047T3 (da)	2005-06-06
NO325080B1 (no)	2008-01-28
HK1115728A1 (en)	2008-12-05
ZA200402544B (en)	2005-04-26
EA006392B1 (ru)	2005-12-29
EP1430034B1 (en)	2005-02-09
NZ532104A (en)	2005-10-28
AU2002330656A2 (en)	2003-04-07
HK1069817A1 (en)	2005-06-03
US20040242873A1 (en)	2004-12-02
BR0212932A (pt)	2004-10-13
SK1902004A3 (en)	2004-10-05
EA006942B1 (ru)	2006-06-30
WO2003027078A1 (en)	2003-04-03
KR100890667B1 (ko)	2009-03-26
SK1892004A3 (en)	2004-10-05
CZ2004528A3 (cs)	2004-08-18
EA200400470A1 (ru)	2004-08-26
US20050043314A1 (en)	2005-02-24

Legal Events

Date	Code	Title	Description
2010-04-26	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
HUP0100615A2 (hu)	2001-10-28	Szubsztituált 2-(2,6-dioxo-3-fluoro-piperidin-3-il)-izoindolinok és ezek alkalmazása TNFalfa-szint csökkentésére
HRP20040317A2 (en)	2006-06-30	1,8-naphthyridine derivatives as antidiabetics
ATE505462T1 (de)	2011-04-15	Neue biologischaktive molekü le
DK1430047T3 (da)	2005-06-06	Substituerede alkylaminopyridazinonderivater, fremgangsmåde til fremstilling deraf og en farmaceutisk sammensætning indeholdende disse
GB0223232D0 (en)	2002-11-13	Chemical compounds
TW200607808A (en)	2006-03-01	Pyrido-pyrimidine derivatives, preparation thereof and application thereof
HUP0402033A2 (hu)	2005-02-28	2-Amino-4-piridil-metil-tiazolin-származékok alkalmazása az indukálható NO-szintetáz inhibitoraként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
AP1396A (en)	2005-04-19	1-Trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives.
MXPA04003741A (es)	2004-07-23	Derivados novedosos de hidroxialquil indolocarbazol, metodo de preparacion y composiciones farmaceuticas que los contienen.
SI1501823T1 (sl)	2006-06-30	Novi piperidinil-alkilamino-piridazinonski derivati, postopek za njihovo pripravo in farmacevtski sestavki, ki vsebujejo te spojine
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