NO20041922L - Benzamid og heteroarylamid som P2X7-reseptorantagonister - Google Patents

Benzamid og heteroarylamid som P2X7-reseptorantagonister

Info

Publication number
NO20041922L
NO20041922L NO20041922A NO20041922A NO20041922L NO 20041922 L NO20041922 L NO 20041922L NO 20041922 A NO20041922 A NO 20041922A NO 20041922 A NO20041922 A NO 20041922A NO 20041922 L NO20041922 L NO 20041922L
Authority
NO
Norway
Prior art keywords
heteroarylamide
benzamide
receptor antagonists
antagonists
receptor
Prior art date
Application number
NO20041922A
Other languages
English (en)
Norwegian (no)
Inventor
Allen Jacob Duplantier
Chakrapani Subramanyam
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20041922L publication Critical patent/NO20041922L/no

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
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    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
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    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
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    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
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NO20041922A 2001-11-12 2004-05-11 Benzamid og heteroarylamid som P2X7-reseptorantagonister NO20041922L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33678101P 2001-11-12 2001-11-12
PCT/IB2002/004613 WO2003042191A1 (en) 2001-11-12 2002-11-04 Benzamide and heteroarylamide as p2x7 receptor antagonists

Publications (1)

Publication Number Publication Date
NO20041922L true NO20041922L (no) 2004-06-01

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NO20041922A NO20041922L (no) 2001-11-12 2004-05-11 Benzamid og heteroarylamid som P2X7-reseptorantagonister

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US (2) US7214677B2 (de)
EP (1) EP1448535B1 (de)
JP (1) JP4365218B2 (de)
KR (1) KR20050043785A (de)
CN (1) CN1585755A (de)
AP (1) AP2004003028A0 (de)
AR (1) AR038365A1 (de)
AT (1) ATE502020T1 (de)
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CA (1) CA2466724C (de)
CY (1) CY1111405T1 (de)
DE (1) DE60239485D1 (de)
DK (1) DK1448535T3 (de)
EA (1) EA200400488A1 (de)
EC (1) ECSP045097A (de)
ES (1) ES2358988T3 (de)
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HN (1) HN2002000319A (de)
HU (1) HUP0401936A3 (de)
IL (1) IL161329A0 (de)
IS (1) IS7216A (de)
MA (1) MA27144A1 (de)
MX (1) MXPA04004465A (de)
NO (1) NO20041922L (de)
OA (1) OA12718A (de)
PA (1) PA8557501A1 (de)
PE (1) PE20030537A1 (de)
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