NO20044262L - Tiazolidinkarboksamidderivater som modulatorer av prostaglandin F-reseptoren - Google Patents
Tiazolidinkarboksamidderivater som modulatorer av prostaglandin F-reseptorenInfo
- Publication number
- NO20044262L NO20044262L NO20044262A NO20044262A NO20044262L NO 20044262 L NO20044262 L NO 20044262L NO 20044262 A NO20044262 A NO 20044262A NO 20044262 A NO20044262 A NO 20044262A NO 20044262 L NO20044262 L NO 20044262L
- Authority
- NO
- Norway
- Prior art keywords
- prostaglandin
- modulators
- receptor
- carboxamide derivatives
- thiazolidine carboxamide
- Prior art date
Links
- YDGXLVKDGGLWPF-UHFFFAOYSA-N 1,3-thiazolidine-2-carboxamide Chemical class NC(=O)C1NCCS1 YDGXLVKDGGLWPF-UHFFFAOYSA-N 0.000 title abstract 2
- 102000000471 Prostaglandin F receptors Human genes 0.000 title 1
- 108050008995 Prostaglandin F receptors Proteins 0.000 title 1
- 208000005171 Dysmenorrhea Diseases 0.000 abstract 1
- 206010013935 Dysmenorrhoea Diseases 0.000 abstract 1
- 208000005107 Premature Birth Diseases 0.000 abstract 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 abstract 1
- 206010036590 Premature baby Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02100314 | 2002-03-28 | ||
| PCT/EP2003/050083 WO2003082278A1 (en) | 2002-03-28 | 2003-03-27 | Thiazolidine carboxamide derivatives as modulators of the prostaglandin f receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20044262L true NO20044262L (no) | 2004-10-07 |
Family
ID=28459561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20044262A NO20044262L (no) | 2002-03-28 | 2004-10-07 | Tiazolidinkarboksamidderivater som modulatorer av prostaglandin F-reseptoren |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20050215605A1 (de) |
| EP (1) | EP1487442B1 (de) |
| JP (1) | JP4602672B2 (de) |
| KR (1) | KR20040095311A (de) |
| CN (1) | CN100484524C (de) |
| AT (1) | ATE489951T1 (de) |
| AU (2) | AU2003240757B2 (de) |
| BR (1) | BR0308748A (de) |
| CA (1) | CA2477265A1 (de) |
| DE (1) | DE60335175D1 (de) |
| EA (1) | EA007328B1 (de) |
| ES (1) | ES2360882T3 (de) |
| HR (1) | HRP20040759A2 (de) |
| IL (1) | IL164212A0 (de) |
| MX (1) | MXPA04009374A (de) |
| NO (1) | NO20044262L (de) |
| PL (1) | PL372919A1 (de) |
| RS (1) | RS81604A (de) |
| UA (1) | UA78021C2 (de) |
| WO (1) | WO2003082278A1 (de) |
| ZA (1) | ZA200406763B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2360882T3 (es) * | 2002-03-28 | 2011-06-10 | Merck Serono Sa | Derivados de tiazolidina carboxamida como moduladores del receptor de prostaglandina f. |
| CA2511970C (en) | 2003-01-14 | 2012-06-26 | Cytokinetics, Inc. | Urea derivatives useful in the treatment of heart failure |
| MY150129A (en) | 2004-04-09 | 2013-11-29 | Archer Daniels Midland Co | Method of preparing fatty acid alkyl esters from waste or recycled fatty acid stock |
| BRPI0512193B8 (pt) | 2004-06-17 | 2021-05-25 | Cytokinetics Inc | composto ou sal farmaceuticamente aceitável, composição farmacêutica, e, uso do composto ou sal |
| US7176222B2 (en) | 2004-07-27 | 2007-02-13 | Cytokinetics, Inc. | Syntheses of ureas |
| ES2419007T3 (es) | 2005-12-15 | 2013-08-19 | Cytokinetics, Inc. | Ciertas entidades químicas, composiciones y procedimientos |
| US7825120B2 (en) | 2005-12-15 | 2010-11-02 | Cytokinetics, Inc. | Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas |
| US7718657B2 (en) | 2005-12-16 | 2010-05-18 | Cytokinetics, Inc. | Certain indanyl urea modulators of the cardiac sarcomere |
| EP1962852B1 (de) | 2005-12-19 | 2017-01-25 | Cytokinetics, Inc. | Verbindungen, zusammensetzungen und verfahren |
| CN103804338A (zh) * | 2006-02-07 | 2014-05-21 | 株式会社·R-技术上野 | 用于制备前列腺素衍生物的方法 |
| US20090163586A1 (en) | 2007-12-20 | 2009-06-25 | Astrazeneca Ab | Bis-(Sulfonylamino) Derivatives in Therapy 205 |
| WO2011014649A1 (en) * | 2009-07-29 | 2011-02-03 | Duke University | Compositions and methods for inhibiting hair growth |
| MY157429A (en) | 2011-06-24 | 2016-06-15 | Amgen Inc | Trpm8 antagonists and their use in treatments |
| JP2014517074A (ja) | 2011-06-24 | 2014-07-17 | アムジエン・インコーポレーテツド | Ｔｒｐｍ８アンタゴニストおよび治療におけるそれらの使用 |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| US20160264536A1 (en) | 2013-10-23 | 2016-09-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| ES2915948T3 (es) * | 2016-01-04 | 2022-06-27 | ObsEva SA | Administración conjunta de alfa-aminoéster de derivado de hidroxipropiltiazolidin-carboxamida y un agente tocolítico |
| US9447055B1 (en) | 2016-01-04 | 2016-09-20 | Merck Serono S.A. | α-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof |
| BR112018013597A2 (pt) * | 2016-01-04 | 2019-01-08 | ObsEva S.A. | composição farmacêutica, método para tratar ou impedir o trabalho de parto prematuro, método para impedir o trabalho de parto antes do parto cesariana, método para tratar ou impedir a dismenorreia e kit |
| EA202092538A1 (ru) * | 2016-10-13 | 2021-05-31 | Мерк Сероно С.А. | Альфа-сложные аминоэфиры производного гидроксипропилтиазолидин карбоксамида и его солевая форма, кристаллический полиморф |
| CN109790136B (zh) * | 2016-12-22 | 2024-01-12 | 广州华睿光电材料有限公司 | 含呋喃交联基团的聚合物及其应用 |
| US11534428B1 (en) | 2018-05-16 | 2022-12-27 | Xoma (Us) Llc | Compositions and methods for delaying the incidence of labor |
| CA3198802A1 (en) | 2020-11-16 | 2022-05-19 | Jean-Pierre Gotteland | Compositions and methods for the treatment or prevention of preterm labor |
| US20240024295A1 (en) * | 2020-12-11 | 2024-01-25 | Elise A. Olsen | Compositions and methods for inhibiting hair growth |
| WO2025124698A1 (en) | 2023-12-12 | 2025-06-19 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
| WO2025132542A1 (en) | 2023-12-19 | 2025-06-26 | Idorsia Pharmaceuticals Ltd | Macrocyclic orexin agonists |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4016270A (en) * | 1975-10-31 | 1977-04-05 | Alza Corporation | Method for treating dysmenorrhea with a uterine therapeutic system |
| JPH0662529B2 (ja) * | 1984-07-13 | 1994-08-17 | 三共株式会社 | アミノ酸誘導体 |
| JPS6450818A (en) * | 1987-08-20 | 1989-02-27 | Tsumura & Co | Prostaglandin f2alpha-inhibitor |
| US5338755A (en) * | 1990-07-31 | 1994-08-16 | Elf Sanofi | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present |
| US6271201B1 (en) | 1993-07-15 | 2001-08-07 | Board Of Regents, The University Of Texas System | Methods for the selective regulation of placental prostanoids and inhibition of labor using IGF-I |
| IL128661A (en) * | 1996-08-28 | 2001-10-31 | Procter & Gamble | Teleprotease inhibitors 1, 3 - diethocycles and pharmaceutical preparations containing them |
| HUP0002680A3 (en) * | 1997-07-31 | 2001-12-28 | American Home Prod | Benzyl compounds which inhibit leukocyte adhesion mediated by vla-4 |
| AR016133A1 (es) * | 1997-07-31 | 2001-06-20 | Wyeth Corp | Compuesto de carbamiloxi que inhiben la adhesion de leucocitos mediada por vla-4, compuestos que son prodrogas de dichos compuestos, composicionfarmaceutica, metodo para fijar vla-4 a una muestra biologica, metodo para el tratamiento de una condicion inflamatoria |
| US6645939B1 (en) * | 1997-11-24 | 2003-11-11 | Merck & Co., Inc. | Substituted β-alanine derivatives as cell adhesion inhibitors |
| ES2360882T3 (es) * | 2002-03-28 | 2011-06-10 | Merck Serono Sa | Derivados de tiazolidina carboxamida como moduladores del receptor de prostaglandina f. |
-
2003
- 2003-03-27 ES ES03730168T patent/ES2360882T3/es not_active Expired - Lifetime
- 2003-03-27 ZA ZA200406763A patent/ZA200406763B/en unknown
- 2003-03-27 WO PCT/EP2003/050083 patent/WO2003082278A1/en not_active Ceased
- 2003-03-27 RS YU81604A patent/RS81604A/sr unknown
- 2003-03-27 AT AT03730168T patent/ATE489951T1/de not_active IP Right Cessation
- 2003-03-27 PL PL03372919A patent/PL372919A1/xx not_active Application Discontinuation
- 2003-03-27 HR HRP20040759 patent/HRP20040759A2/hr not_active Application Discontinuation
- 2003-03-27 CN CNB038115603A patent/CN100484524C/zh not_active Expired - Lifetime
- 2003-03-27 DE DE60335175T patent/DE60335175D1/de not_active Expired - Lifetime
- 2003-03-27 CA CA002477265A patent/CA2477265A1/en not_active Abandoned
- 2003-03-27 UA UA20040907830A patent/UA78021C2/uk unknown
- 2003-03-27 MX MXPA04009374A patent/MXPA04009374A/es active IP Right Grant
- 2003-03-27 AU AU2003240757A patent/AU2003240757B2/en not_active Ceased
- 2003-03-27 JP JP2003579816A patent/JP4602672B2/ja not_active Expired - Lifetime
- 2003-03-27 KR KR10-2004-7015040A patent/KR20040095311A/ko not_active Ceased
- 2003-03-27 BR BR0308748-4A patent/BR0308748A/pt not_active IP Right Cessation
- 2003-03-27 IL IL16421203A patent/IL164212A0/xx unknown
- 2003-03-27 EP EP03730168A patent/EP1487442B1/de not_active Expired - Lifetime
- 2003-03-27 EA EA200401270A patent/EA007328B1/ru unknown
- 2003-03-27 US US10/508,014 patent/US20050215605A1/en not_active Abandoned
-
2004
- 2004-10-07 NO NO20044262A patent/NO20044262L/no not_active Application Discontinuation
-
2008
- 2008-06-17 US US12/140,682 patent/US8415480B2/en not_active Expired - Lifetime
- 2008-08-19 AU AU2008207407A patent/AU2008207407A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60335175D1 (de) | 2011-01-13 |
| JP2005531524A (ja) | 2005-10-20 |
| EP1487442A1 (de) | 2004-12-22 |
| US8415480B2 (en) | 2013-04-09 |
| US20050215605A1 (en) | 2005-09-29 |
| US20080255094A1 (en) | 2008-10-16 |
| HK1075215A1 (zh) | 2005-12-09 |
| BR0308748A (pt) | 2005-01-11 |
| JP4602672B2 (ja) | 2010-12-22 |
| WO2003082278A1 (en) | 2003-10-09 |
| EA200401270A1 (ru) | 2005-02-24 |
| AU2008207407A1 (en) | 2008-09-11 |
| PL372919A1 (en) | 2005-08-08 |
| CN1655780A (zh) | 2005-08-17 |
| KR20040095311A (ko) | 2004-11-12 |
| EP1487442B1 (de) | 2010-12-01 |
| EA007328B1 (ru) | 2006-08-25 |
| US20090215749A9 (en) | 2009-08-27 |
| HRP20040759A2 (en) | 2004-12-31 |
| UA78021C2 (en) | 2007-02-15 |
| ES2360882T3 (es) | 2011-06-10 |
| CA2477265A1 (en) | 2003-10-09 |
| ATE489951T1 (de) | 2010-12-15 |
| MXPA04009374A (es) | 2005-01-25 |
| IL164212A0 (en) | 2005-12-18 |
| ZA200406763B (en) | 2005-09-30 |
| RS81604A (sr) | 2006-12-15 |
| AU2003240757B2 (en) | 2008-07-03 |
| AU2003240757A1 (en) | 2003-10-13 |
| CN100484524C (zh) | 2009-05-06 |
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Legal Events
| Date | Code | Title | Description |
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| CREP | Change of representative |
Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS |
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| FC2A | Withdrawal, rejection or dismissal of laid open patent application |