NO20044341L - Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin - Google Patents

Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin

Info

Publication number: NO20044341L
Authority: NO; Norway
Prior art keywords: homoerythromycin; deoxo; aza; methyl; pseudopolymorph
Prior art date: 2002-03-18

Application number

NO20044341A

Other languages

English (en)

Norwegian (no)

Inventor

Mladen Vinkovic

Mikjenko Dumic

Original Assignee

Pliva Istrazivacki Inst Doo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-18

Filing date

2004-10-13

Publication date

2004-11-23

2004-10-13 Application filed by Pliva Istrazivacki Inst Doo filed Critical Pliva Istrazivacki Inst Doo

2004-11-23 Publication of NO20044341L publication Critical patent/NO20044341L/no

Links

239000013078 crystal Substances 0.000 abstract 2
MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Thermal Transfer Or Thermal Recording In General (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Instructional Devices (AREA)
Finger-Pressure Massage (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20044341A 2002-03-18 2004-10-13 Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin NO20044341L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
HR20020231A HRP20020231A2 (en)	2002-03-18	2002-03-18	ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
US39361202P	2002-07-03	2002-07-03
US39470502P	2002-07-08	2002-07-08
PCT/IB2003/000987 WO2003077830A2 (en)	2002-03-18	2003-03-18	9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives

Publications (1)

Publication Number	Publication Date
NO20044341L true NO20044341L (no)	2004-11-23

Family

ID=28045976

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20044341A NO20044341L (no)	2002-03-18	2004-10-13	Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin

Country Status (23)

Country	Link
US (1)	US7569549B2 (is)
EP (2)	EP1627883A1 (is)
JP (1)	JP2005529082A (is)
KR (1)	KR20050002872A (is)
CN (1)	CN1642966A (is)
AT (1)	ATE440104T1 (is)
AU (1)	AU2003215779A1 (is)
BG (1)	BG108874A (is)
BR (1)	BR0308644A (is)
CA (1)	CA2479211A1 (is)
DE (1)	DE60328872D1 (is)
EA (1)	EA200401217A1 (is)
ES (1)	ES2331733T3 (is)
HR (2)	HRP20020231A2 (is)
IL (1)	IL163836A0 (is)
IS (1)	IS7449A (is)
MX (1)	MXPA04009009A (is)
NO (1)	NO20044341L (is)
NZ (1)	NZ535477A (is)
PL (1)	PL372468A1 (is)
RS (1)	RS82504A (is)
TN (1)	TNSN04166A1 (is)
WO (1)	WO2003077830A2 (is)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20020231A2 (en)	2002-03-18	2003-12-31	Pliva D D	ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
HRP20020614A2 (en) *	2002-07-22	2004-06-30	PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o.	Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
EP1648473B1 (en)	2003-07-24	2009-01-28	PLIVA HRVATSKA d.o.o.	Single dose fast dissolving azithromycin
EP1878432A1 (en) *	2003-07-24	2008-01-16	Pliva - Research and Development Ltd.	Single dose fast dissolving azithromycin
WO2005053652A1 (en)	2003-12-04	2005-06-16	Pfizer Products Inc.	Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
CA2549225A1 (en) *	2003-12-04	2005-06-16	Pfizer Products Inc.	Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions containing preferably a poloxamer and a glyceride
ATE399536T1 (de) *	2003-12-04	2008-07-15	Pfizer Prod Inc	Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
US6984403B2 (en) *	2003-12-04	2006-01-10	Pfizer Inc.	Azithromycin dosage forms with reduced side effects
BRPI0416534A (pt)	2003-12-04	2007-01-09	Pfizer Prod Inc	composições multiparticuladas com estabilidade melhorada
EP1694304A2 (en) *	2003-12-04	2006-08-30	Pfizer Products Inc.	Azithromycin multiparticulate dosage forms by liquid-based processes
US20060116336A1 (en) *	2004-03-17	2006-06-01	American Pharmaceutical Partners, Inc.	Lyophilized azithromycin formulation
US7468428B2 (en) *	2004-03-17	2008-12-23	App Pharmaceuticals, Llc	Lyophilized azithromycin formulation

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SI8110592A8 (en)	1981-03-06	1996-06-30	Pliva Pharm & Chem Works	Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
RO107257B1 (ro) *	1987-07-09	1993-10-30	Pfizer	Procedeu de obtinere a unui dihidrat de azitromicina, cristalin
HRP20020231A2 (en)	2002-03-18	2003-12-31	Pliva D D	ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
EP0699207B1 (en)	1993-05-19	1997-06-25	Pfizer Inc.	Intermediate for azithromycin
HRP940251B1 (en)	1994-04-15	1998-12-31	Stjepan Mutak	Process for the preparation of azithromycin dihydrochloride
ES2122905B1 (es) *	1996-07-11	1999-11-16	Astur Pharma Sa	Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
PT102130A (pt)	1998-03-13	1999-09-30	Hovione Sociedade Quimica S A	Processo de preparacao de dihidrato de azitromicina
CN1205338A (zh)	1998-05-08	1999-01-20	刘万忠	阿奇霉素水溶性盐的合成新方法及其在医药上的用途
TW546302B (en) *	1998-05-08	2003-08-11	Biochemie Sa	Improvements in macrolide production
US6245903B1 (en)	1998-08-21	2001-06-12	Apotex, Inc.	Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
AU768219B2 (en) *	1998-11-30	2003-12-04	Teva Pharmaceutical Industries Ltd.	Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
ES2267549T3 (es) *	1999-06-29	2007-03-16	Sandoz Ag	Procedimiento para la produccion de azitromicina.
ES2177373B1 (es) *	1999-11-26	2003-11-01	Astur Pharma Sa	Preparacion de azitromicina en su forma no cristalina
CA2396426A1 (en) *	2000-01-04	2001-07-12	Teva Pharmaceutical Industries Ltd.	Preparation method of azithromycin dihydrate
ES2162764B1 (es) *	2000-05-17	2003-04-01	Ercros Ind Sa	Forma polimorfica del dihidrato de azitromicina, y su procedimiento deobtencion.
ES2260047T3 (es)	2000-07-25	2006-11-01	Laboratorio Silanes, S.A. De C.V.	Proceso de etapa unica para la preparacion de 7,16-deoxi-2-aza-10-o-cladinosil-12-o-desosaminil-4,5-dihidroxi-6-etil-3,5,9,11,13,15-hexametilbiciclo(11.2.1)hexadeca-1(2)-en-ona y obtencion de una forma nueva de 9-deoxo-9a-metil-9a-homoeritromicina a.
WO2002015842A2 (en) *	2000-08-23	2002-02-28	Wockhardt Limited	Process for preparation of anhydrous azithromycin
EE05200B1 (et) *	2000-11-27	2009-08-17	Biochemie S.A.	Asitromtsiin monohdraadina, selle valmistamismeetod ja selle kasutamine ravimkoostises
KR100491183B1 (ko)	2001-03-21	2005-05-25	한미약품 주식회사	아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
KR100431431B1 (ko)	2001-04-25	2004-05-14	한미약품 주식회사	아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
HRP20010301A2 (en)	2001-04-27	2001-12-31	Pliva D D	New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
DK1390377T3 (da)	2001-05-22	2006-06-19	Pfizer Prod Inc	Ny krystalform af azithromycin
US6861413B2 (en)	2001-05-22	2005-03-01	Pfizer Inc.	Stable non-dihydrate azithromycin oral suspensions
PL371259A1 (pl)	2001-12-21	2005-06-13	Pfizer Products Inc.	Bezpośrednio sprasowywalne preparaty azytromycyny
AU2002353316A1 (en)	2001-12-21	2003-07-09	Pfizer Products Inc.	Methods for wet granulating azithromycin
BR0307331A (pt)	2002-02-01	2004-12-07	Pfizer Prod Inc	Formulações granuladas a seco de azitromicina
ITMI20021209A1 (it)	2002-06-04	2003-12-04	Chemi Spa	Processo di preparazione di azitromicina ad elevata purezza

2002
- 2002-03-18 HR HR20020231A patent/HRP20020231A2/hr not_active Application Discontinuation
2003
- 2003-03-17 US US10/390,573 patent/US7569549B2/en not_active Expired - Lifetime
- 2003-03-18 EA EA200401217A patent/EA200401217A1/ru unknown
- 2003-03-18 JP JP2003575884A patent/JP2005529082A/ja not_active Abandoned
- 2003-03-18 PL PL03372468A patent/PL372468A1/xx unknown
- 2003-03-18 CN CNA038063263A patent/CN1642966A/zh active Pending
- 2003-03-18 KR KR10-2004-7014757A patent/KR20050002872A/ko not_active Withdrawn
- 2003-03-18 WO PCT/IB2003/000987 patent/WO2003077830A2/en not_active Ceased
- 2003-03-18 MX MXPA04009009A patent/MXPA04009009A/es not_active Application Discontinuation
- 2003-03-18 EP EP05023731A patent/EP1627883A1/en not_active Withdrawn
- 2003-03-18 RS YU82504A patent/RS82504A/sr unknown
- 2003-03-18 AU AU2003215779A patent/AU2003215779A1/en not_active Abandoned
- 2003-03-18 DE DE60328872T patent/DE60328872D1/de not_active Expired - Fee Related
- 2003-03-18 IL IL16383603A patent/IL163836A0/xx unknown
- 2003-03-18 ES ES03744475T patent/ES2331733T3/es not_active Expired - Lifetime
- 2003-03-18 HR HR20040858A patent/HRP20040858A2/xx not_active Application Discontinuation
- 2003-03-18 AT AT03744475T patent/ATE440104T1/de not_active IP Right Cessation
- 2003-03-18 CA CA002479211A patent/CA2479211A1/en not_active Abandoned
- 2003-03-18 EP EP03744475A patent/EP1485393B1/en not_active Expired - Lifetime
- 2003-03-18 NZ NZ535477A patent/NZ535477A/en unknown
- 2003-03-18 BR BR0308644-5A patent/BR0308644A/pt not_active Application Discontinuation
2004
- 2004-09-03 TN TNP2004000166A patent/TNSN04166A1/en unknown
- 2004-09-14 BG BG108874A patent/BG108874A/xx unknown
- 2004-09-16 IS IS7449A patent/IS7449A/is unknown
- 2004-10-13 NO NO20044341A patent/NO20044341L/no unknown

Also Published As

Publication number	Publication date
TNSN04166A1 (en)	2007-03-12
PL372468A1 (en)	2005-07-25
IS7449A (is)	2004-09-16
CN1642966A (zh)	2005-07-20
EP1485393B1 (en)	2009-08-19
ES2331733T3 (es)	2010-01-14
HRP20020231A2 (en)	2003-12-31
BR0308644A (pt)	2005-01-25
EP1627883A1 (en)	2006-02-22
US7569549B2 (en)	2009-08-04
KR20050002872A (ko)	2005-01-10
MXPA04009009A (es)	2005-06-17
ATE440104T1 (de)	2009-09-15
CA2479211A1 (en)	2003-09-25
RS82504A (sr)	2006-12-15
JP2005529082A (ja)	2005-09-29
AU2003215779A1 (en)	2003-09-29
IL163836A0 (en)	2005-12-18
US20040014951A1 (en)	2004-01-22
EP1485393A2 (en)	2004-12-15
HRP20040858A2 (en)	2005-06-30
WO2003077830A3 (en)	2004-05-13
NZ535477A (en)	2006-11-30
EA200401217A1 (ru)	2005-02-24
BG108874A (en)	2005-12-30
DE60328872D1 (en)	2009-10-01
WO2003077830A2 (en)	2003-09-25

Publication	Publication Date	Title
NO20044341L (no)	2004-11-23	Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin
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