NO20050667L - N-substituerte-1H-indol-5-propionsyreforbindelser som PPAR agonister nyttige for behandling av diabetes - Google Patents

N-substituerte-1H-indol-5-propionsyreforbindelser som PPAR agonister nyttige for behandling av diabetes

Info

Publication number: NO20050667L
Authority: NO; Norway
Prior art keywords: indole; diabetes; substituted; treatment; propionic acid
Prior art date: 2002-09-12

Application number

NO20050667A

Other languages

English (en)

Norwegian (no)

Inventor

Beat Wirz

Peter Mohr

Alfred Binggeli

Uwe Grether

Hans Hilpert

Markus Meyer

Hans-Peter Maerki

Hans Iding

Roland Humm

Bernd Kuhn

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-12

Filing date

2005-02-08

Publication date

2005-06-08

2005-02-08 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2005-06-08 Publication of NO20050667L publication Critical patent/NO20050667L/no

Links

-1 N-substituted-1H-indole-5-propionic acid compounds Chemical class 0.000 title 1
102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title 1
108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title 1
239000000556 agonist Substances 0.000 title 1
206010012601 diabetes mellitus Diseases 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Obesity (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Emergency Medicine (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20050667A 2002-09-12 2005-02-08 N-substituerte-1H-indol-5-propionsyreforbindelser som PPAR agonister nyttige for behandling av diabetes NO20050667L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02020477		2002-09-12
PCT/EP2003/009819 WO2004024726A1 (en)	2002-09-12	2003-09-04	N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes

Publications (1)

Publication Number	Publication Date
NO20050667L true NO20050667L (no)	2005-06-08

Family

ID=31985028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20050667A NO20050667L (no)	2002-09-12	2005-02-08	N-substituerte-1H-indol-5-propionsyreforbindelser som PPAR agonister nyttige for behandling av diabetes

Country Status (29)

Country	Link
US (1)	US6890947B2 (de)
EP (1)	EP1539746B1 (de)
JP (1)	JP4286782B2 (de)
KR (1)	KR100645684B1 (de)
CN (1)	CN100577660C (de)
AR (1)	AR041218A1 (de)
AT (1)	ATE345340T1 (de)
AU (1)	AU2003267041B2 (de)
BR (1)	BR0314261A (de)
CA (1)	CA2494601C (de)
DE (1)	DE60309719T2 (de)
DK (1)	DK1539746T3 (de)
ES (1)	ES2275105T3 (de)
GT (1)	GT200300194A (de)
HR (1)	HRP20050212A2 (de)
MX (1)	MXPA05002704A (de)
MY (1)	MY135646A (de)
NO (1)	NO20050667L (de)
NZ (1)	NZ537979A (de)
PA (1)	PA8581701A1 (de)
PE (1)	PE20050050A1 (de)
PL (1)	PL375878A1 (de)
PT (1)	PT1539746E (de)
RU (1)	RU2296759C2 (de)
SI (1)	SI1539746T1 (de)
TW (1)	TWI248933B (de)
UY (1)	UY27975A1 (de)
WO (1)	WO2004024726A1 (de)
ZA (1)	ZA200501273B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10022925A1 (de) *	2000-05-11	2001-11-15	Basf Ag	Substituierte Indole als PARP-Inhibitoren
MXPA05010812A (es) *	2003-04-17	2006-03-30	Kalypsys Inc	Acido(3-{3-?(2,4- bis-trifluorometil -bencil)-(5-etil -pirimidin-2-il) -amino]- propoxi}-fenil) -acetico y compuestos relacionados como moduladores de receptores activados por proliferador de peroxisoma y metodos de tratamiento de trastornos metaboli
US20050203151A1 (en) *	2003-12-19	2005-09-15	Kalypsys, Inc.	Novel compounds, compositions and uses thereof for treatment of metabolic disorders and related conditions
US7405236B2 (en) *	2004-08-16	2008-07-29	Hoffman-La Roche Inc.	Indole derivatives comprising an acetylene group
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
NO20083270L (no) *	2008-07-23	2010-01-25	Thia Medica As	Indolforbindelser
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8933024B2 (en)	2010-06-18	2015-01-13	Sanofi	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
EP2567959B1 (de)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4011326A (en) *	1975-07-29	1977-03-08	Merck & Co., Inc.	2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents
DK151884C (da) *	1979-03-07	1988-06-13	Pfizer	Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
CA1247547A (en) *	1983-06-22	1988-12-28	Paul Hadvary	Leucine derivatives
CA1270837A (en)	1984-12-21	1990-06-26	Hoffmann-La Roche Limited	Oxetanones
CA1328881C (en)	1984-12-21	1994-04-26	Pierre Barbier	Process for the manufacture of oxetanones
CA2035972C (en)	1990-02-23	2006-07-11	Martin Karpf	Process for the preparation of oxetanones
US5089514A (en) *	1990-06-14	1992-02-18	Pfizer Inc.	3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
US5274143A (en)	1991-07-23	1993-12-28	Hoffmann-La Roche Inc.	Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione
NZ253742A (en)	1992-07-03	1997-06-24	Smithkline Beecham Plc	Heterocyclylaminoalkoxy substituted phenyl derivatives and pharmaceutical compositions
GB9225386D0 (en)	1992-12-04	1993-01-27	Smithkline Beecham Plc	Novel compounds
DE4317320A1 (de) *	1993-05-25	1994-12-01	Boehringer Mannheim Gmbh	Neue Thiazolidindione und diese enthaltende Arzneimittel
GB9326171D0 (en)	1993-12-22	1994-02-23	Smithkline Beecham Plc	Novel compounds
IL117208A0 (en) *	1995-02-23	1996-06-18	Nissan Chemical Ind Ltd	Indole type thiazolidines
KR100430059B1 (ko) *	1995-04-10	2004-09-24	후지사와 야꾸힝 고교 가부시키가이샤	cGMP-PDE억제제로서의인돌유도체
JPH09176162A (ja) *	1995-12-22	1997-07-08	Toubishi Yakuhin Kogyo Kk	チアゾリジンジオン誘導体及びその製造法並びにそれを含む医薬組成物
GB9600464D0 (en)	1996-01-09	1996-03-13	Smithkline Beecham Plc	Novel method
ES2217392T3 (es) *	1996-02-02	2004-11-01	MERCK & CO., INC.	Agentes antidiabeticos.
RU2190609C2 (ru) *	1996-12-10	2002-10-10	Бристол-Маерс Сквибб Компани	Производные бензодиоксола, бензофурана, дигидробензофурана и бензодиоксана и содержащие их композиции
US6004996A (en) *	1997-02-05	1999-12-21	Hoffman-La Roche Inc.	Tetrahydrolipstatin containing compositions
DE19711616A1 (de) *	1997-03-20	1998-09-24	Boehringer Mannheim Gmbh	Verbessertes Verfahren zur Herstellung von Thiazolidindionen
US6121397A (en) *	1997-07-14	2000-09-19	Xerox Corporation	Polymerization processes using oligomeric compound, monomer and surfactant
HN1998000118A (es)	1997-08-27	1999-02-09	Pfizer Prod Inc	2 - aminopiridinas que contienen sustituyentes de anillos condensados.
DE69815008T2 (de)	1997-09-19	2004-04-01	Ssp Co., Ltd.	Alfa-substituierte Phenylpropionsäurederivate und diese enthaltende Arzneimittel
WO1999008501A2 (en)	1998-04-23	1999-02-25	Dr. Reddy's Research Foundation	New heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
GB9817118D0 (en)	1998-08-07	1998-10-07	Glaxo Group Ltd	Pharmaceutical compounds
DE69916288T2 (de)	1998-08-14	2005-03-24	F. Hoffmann-La Roche Ag	Lipasehemmer und chitosan enthaltende arzneimittel
BR9912980B1 (pt)	1998-08-14	2013-10-22		Composição farmacêutica administrável oralmente, tablete de mascar contendo a mesma e utilização da mesma
GB9914977D0 (en)	1999-06-25	1999-08-25	Glaxo Group Ltd	Chemical compounds
DK1078923T3 (da)	1999-08-02	2006-07-10	Hoffmann La Roche	Fremgangsmåde til fremstilling af benzothiophenderivater
JP2004513076A (ja) *	2000-07-25	2004-04-30	メルク　エンド　カムパニー　インコーポレーテッド	糖尿病治療で有用なｎ−置換インドール類
CA2418104A1 (en)	2000-08-23	2002-02-28	Eli Lilly And Company	Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists
DE10117090B4 (de) *	2001-04-06	2013-08-14	Dr. Ing. H.C. F. Porsche Aktiengesellschaft	Wassergekühlte, mehrzylindrige Brennkraftmaschine
WO2003004458A1 (en)	2001-07-03	2003-01-16	Biovitrum Ab	New compounds
EP1442028A4 (de) *	2001-11-06	2009-11-04	Bristol Myers Squibb Co	Substituierte säurederivate, die sich als antidiabetika und mittel gegen obesitas eignen, und verfahren
AU2002359160A1 (en)	2001-12-20	2003-07-09	Biovitrum Ab	PIPAZOLO (1,5-a) PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR

2003
- 2003-09-04 NZ NZ537979A patent/NZ537979A/en unknown
- 2003-09-04 ES ES03747962T patent/ES2275105T3/es not_active Expired - Lifetime
- 2003-09-04 CA CA002494601A patent/CA2494601C/en not_active Expired - Fee Related
- 2003-09-04 HR HR20050212A patent/HRP20050212A2/hr not_active Application Discontinuation
- 2003-09-04 PT PT03747962T patent/PT1539746E/pt unknown
- 2003-09-04 WO PCT/EP2003/009819 patent/WO2004024726A1/en not_active Ceased
- 2003-09-04 PL PL03375878A patent/PL375878A1/xx not_active Application Discontinuation
- 2003-09-04 DK DK03747962T patent/DK1539746T3/da active
- 2003-09-04 EP EP03747962A patent/EP1539746B1/de not_active Expired - Lifetime
- 2003-09-04 BR BR0314261-2A patent/BR0314261A/pt not_active IP Right Cessation
- 2003-09-04 MX MXPA05002704A patent/MXPA05002704A/es active IP Right Grant
- 2003-09-04 AU AU2003267041A patent/AU2003267041B2/en not_active Ceased
- 2003-09-04 SI SI200330631T patent/SI1539746T1/sl unknown
- 2003-09-04 KR KR1020057004166A patent/KR100645684B1/ko not_active Expired - Fee Related
- 2003-09-04 JP JP2004535427A patent/JP4286782B2/ja not_active Expired - Fee Related
- 2003-09-04 DE DE60309719T patent/DE60309719T2/de not_active Expired - Lifetime
- 2003-09-04 AT AT03747962T patent/ATE345340T1/de not_active IP Right Cessation
- 2003-09-04 CN CN03821483A patent/CN100577660C/zh not_active Expired - Fee Related
- 2003-09-04 RU RU2005110921/04A patent/RU2296759C2/ru not_active IP Right Cessation
- 2003-09-08 TW TW092124737A patent/TWI248933B/zh not_active IP Right Cessation
- 2003-09-09 PA PA20038581701A patent/PA8581701A1/es unknown
- 2003-09-10 PE PE2003000917A patent/PE20050050A1/es not_active Application Discontinuation
- 2003-09-10 US US10/659,664 patent/US6890947B2/en not_active Expired - Fee Related
- 2003-09-10 MY MYPI20033416A patent/MY135646A/en unknown
- 2003-09-10 GT GT200300194A patent/GT200300194A/es unknown
- 2003-09-10 AR ARP030103266A patent/AR041218A1/es unknown
- 2003-09-11 UY UY27975A patent/UY27975A1/es not_active Application Discontinuation
2005
- 2005-02-08 NO NO20050667A patent/NO20050667L/no not_active Application Discontinuation
- 2005-02-11 ZA ZA200501273A patent/ZA200501273B/en unknown

Also Published As

Publication number	Publication date
UY27975A1 (es)	2004-03-31
ZA200501273B (en)	2006-08-30
PT1539746E (pt)	2007-02-28
ES2275105T3 (es)	2007-06-01
AR041218A1 (es)	2005-05-11
WO2004024726A1 (en)	2004-03-25
CA2494601C (en)	2009-09-29
JP2006503029A (ja)	2006-01-26
DE60309719D1 (de)	2006-12-28
CA2494601A1 (en)	2004-03-25
PA8581701A1 (es)	2004-04-23
MXPA05002704A (es)	2005-05-05
AU2003267041B2 (en)	2007-03-29
TW200418845A (en)	2004-10-01
BR0314261A (pt)	2005-07-26
DE60309719T2 (de)	2007-09-20
KR100645684B1 (ko)	2006-11-15
CN1681808A (zh)	2005-10-12
RU2005110921A (ru)	2006-01-20
DK1539746T3 (da)	2007-03-26
SI1539746T1 (sl)	2007-04-30
RU2296759C2 (ru)	2007-04-10
PL375878A1 (en)	2005-12-12
CN100577660C (zh)	2010-01-06
HRP20050212A2 (en)	2006-05-31
MY135646A (en)	2008-06-30
PE20050050A1 (es)	2005-02-18
US20040053979A1 (en)	2004-03-18
ATE345340T1 (de)	2006-12-15
EP1539746A1 (de)	2005-06-15
TWI248933B (en)	2006-02-11
JP4286782B2 (ja)	2009-07-01
GT200300194A (es)	2004-04-15
US6890947B2 (en)	2005-05-10
NZ537979A (en)	2007-08-31
AU2003267041A1 (en)	2004-04-30
KR20050042809A (ko)	2005-05-10
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Publication	Publication Date	Title
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