NO20051089L - Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer - Google Patents

Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer

Info

Publication number: NO20051089L
Authority: NO; Norway
Prior art keywords: alkyl; amino; hiv protease; benzothiazole; spectrum
Prior art date: 2002-08-02

Application number

NO20051089A

Other languages

English (en)

Norwegian (no)

Inventor

Piet Tom Bert Paul Wigerinck

Daniel P Getman

Dominique Louis Nest Surleraux

Original Assignee

Tibotec Pharm Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-02

Filing date

2005-03-01

Publication date

2005-05-02

2005-03-01 Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd

2005-05-02 Publication of NO20051089L publication Critical patent/NO20051089L/no

Links

XFMNXQKCYJXARU-UHFFFAOYSA-N 2-amino-3h-1,3-benzothiazole-2-sulfonamide Chemical compound C1=CC=C2SC(N)(S(N)(=O)=O)NC2=C1 XFMNXQKCYJXARU-UHFFFAOYSA-N 0.000 title 1
239000004030 hiv protease inhibitor Substances 0.000 title 1
238000001228 spectrum Methods 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 6
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
108010010369 HIV Protease Proteins 0.000 abstract 2
-1 hexahydrofuro [2,3-b] furanyl Chemical group 0.000 abstract 2
UHGULLIUJBCTEF-UHFFFAOYSA-N 2-aminobenzothiazole Chemical class C1=CC=C2SC(N)=NC2=C1 UHGULLIUJBCTEF-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000002971 oxazolyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1
125000000335 thiazolyl group Chemical group 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO20051089A 2002-08-02 2005-03-01 Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer NO20051089L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP02078231		2002-08-02
US42786202P	2002-11-20	2002-11-20
PCT/EP2003/050359 WO2004014371A1 (fr)	2002-08-02	2003-08-04	Inhibiteurs broadspectrum 2-amino-benzothiazole sulfonamide hiv protease inhibitors

Publications (1)

Publication Number	Publication Date
NO20051089L true NO20051089L (no)	2005-05-02

Family

ID=31716850

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20051089A NO20051089L (no)	2002-08-02	2005-03-01	Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer

Country Status (16)

Country	Link
US (2)	US20050267156A1 (fr)
EP (1)	EP1545518A1 (fr)
KR (1)	KR20050025647A (fr)
CN (1)	CN1671380B (fr)
AP (1)	AP1878A (fr)
AU (1)	AU2003262561B2 (fr)
BR (1)	BR0305717A (fr)
CA (1)	CA2492832C (fr)
EA (1)	EA008594B1 (fr)
HR (1)	HRP20050605A2 (fr)
IL (1)	IL166257A (fr)
MX (1)	MXPA05001275A (fr)
NO (1)	NO20051089L (fr)
NZ (1)	NZ538488A (fr)
PL (1)	PL374948A1 (fr)
WO (1)	WO2004014371A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7378441B2 (en) *	2004-05-07	2008-05-27	Sequoia Pharmaceuticals, Inc.	Resistance-repellent retroviral protease inhibitors
JO2841B1 (en) *	2006-06-23	2014-09-15	تيبوتيك فارماسيوتيكالز ليمتد	2-(substituted-amino) -benzothiazole sulfonamide as protease inhibitors HIV (HIV)
US8267163B2 (en) *	2008-03-17	2012-09-18	Visteon Global Technologies, Inc.	Radiator tube dimple pattern
WO2011061590A1 (fr)	2009-11-17	2011-05-26	Hetero Research Foundation	Nouveaux dérivés carboxamides comme inhibiteurs du vih
EP2588455B1 (fr)	2010-07-02	2018-04-04	Gilead Sciences, Inc.	Dérivés de l'acide 2-quinolinyl-acétique en tant que composés antiviraux hiv
MX2012015097A (es)	2010-07-02	2013-05-28	Gilead Sciences Inc	Derivados de acido naft-2-ilacetico para tratar sida.
US9024038B2 (en)	2010-12-27	2015-05-05	Purdue Research Foundation	Compunds and methods for treating HIV
UA111841C2 (uk) *	2011-04-21	2016-06-24	Гіліад Сайєнсіз, Інк.	Сполуки бензотіазолу та їх фармацевтичне застосування
US9376392B2 (en)	2012-01-04	2016-06-28	Gilead Sciences, Inc.	2-(tert-butoxy)-2-(7-methylquinolin-6-yl) acetic acid derivatives for treating AIDS
US9284323B2 (en)	2012-01-04	2016-03-15	Gilead Sciences, Inc.	Naphthalene acetic acid derivatives against HIV infection
UY34750A (es)	2012-04-20	2013-11-29	Gilead Sciences Inc	?compuestos para el tratamiento del hiv, composiciones,métodos de preparación, intermediarios y métodos terapéuticos?.
RS61409B1 (sr) *	2014-12-10	2021-03-31	Tricida Inc	Polimeri koji vezuju protone za oralnu primenu opis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5968942A (en) *	1992-08-25	1999-10-19	G. D. Searle & Co.	α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
EP0715618B1 (fr) *	1993-08-24	1998-12-16	G.D. Searle & Co.	Hydroxyethylamino-sulfonamides aptes a etre utilises comme inhibiteurs de protease retrovirale
AU4828199A (en) *	1998-06-23	2000-01-10	Board Of Trustees Of The University Of Illinois, The	Multi-drug resistant retroviral protease inhibitors and associated methods
US7659404B2 (en) *	2001-02-14	2010-02-09	Tibotec Pharmaceuticals Ltd.	Broad spectrum 2-(substituted-amino)-benzothiazole sulfonamide HIV protease inhibitors

2003
- 2003-08-04 CN CN038184044A patent/CN1671380B/zh not_active Expired - Fee Related
- 2003-08-04 PL PL03374948A patent/PL374948A1/xx not_active Application Discontinuation
- 2003-08-04 EA EA200500298A patent/EA008594B1/ru not_active IP Right Cessation
- 2003-08-04 MX MXPA05001275A patent/MXPA05001275A/es active IP Right Grant
- 2003-08-04 CA CA2492832A patent/CA2492832C/fr not_active Expired - Fee Related
- 2003-08-04 AP AP2005003242A patent/AP1878A/xx active
- 2003-08-04 AU AU2003262561A patent/AU2003262561B2/en not_active Ceased
- 2003-08-04 EP EP03784205A patent/EP1545518A1/fr not_active Ceased
- 2003-08-04 BR BR0305717-8A patent/BR0305717A/pt not_active Application Discontinuation
- 2003-08-04 KR KR1020057001206A patent/KR20050025647A/ko not_active Ceased
- 2003-08-04 WO PCT/EP2003/050359 patent/WO2004014371A1/fr not_active Ceased
- 2003-08-04 US US10/523,445 patent/US20050267156A1/en not_active Abandoned
- 2003-08-04 HR HR20050605A patent/HRP20050605A2/hr not_active Application Discontinuation
- 2003-08-04 NZ NZ538488A patent/NZ538488A/en not_active IP Right Cessation
2005
- 2005-01-12 IL IL166257A patent/IL166257A/en not_active IP Right Cessation
- 2005-03-01 NO NO20051089A patent/NO20051089L/no not_active Application Discontinuation
2009
- 2009-04-20 US US12/426,730 patent/US20090203742A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2004014371A1 (fr)	2004-02-19
EA200500298A1 (ru)	2005-08-25
KR20050025647A (ko)	2005-03-14
EA008594B1 (ru)	2007-06-29
PL374948A1 (en)	2005-11-14
MXPA05001275A (es)	2005-04-28
BR0305717A (pt)	2004-09-28
HRP20050605A2 (en)	2006-02-28
CA2492832A1 (fr)	2004-02-19
US20090203742A1 (en)	2009-08-13
AU2003262561A1 (en)	2004-02-25
CN1671380A (zh)	2005-09-21
EP1545518A1 (fr)	2005-06-29
NZ538488A (en)	2007-10-26
AP1878A (en)	2008-08-13
IL166257A (en)	2013-04-30
AP2005003242A0 (en)	2005-03-31
CA2492832C (fr)	2012-05-22
CN1671380B (zh)	2010-05-26
IL166257A0 (en)	2006-01-15
US20050267156A1 (en)	2005-12-01
AU2003262561B2 (en)	2008-10-16

Legal Events

Date	Code	Title	Description
2014-06-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20051600L (no)	2005-06-13	1,4-disubstituerte piperidinderivater og anvendelse derav som 11-betaHSD1 inhibitorer
NO20082629L (no)	2008-09-05	Macrocyklisk factor VIIa-inhibitorer anvendbare som antikoagulanter
NO20054852L (no)	2005-12-13	GFAT inhibitorer
NO20051089L (no)	2005-05-02	Bredspektrede 2-amino-benzotiazol-sulfonamid-HIV-proteaseinhibitorer
NO20051965D0 (no)	2005-04-22	Nye piperidinderivater for anvendelse ved behandling av kemokinmedierte sykdomstilstander.
NO20054224L (no)	2005-11-10	Nye 2-pyridinkarboksamidderivater
DK1263722T3 (da)	2011-01-03	Farmaceutiske sammensætninger, som indeholder azetidinderivat, nye azetidinderivater og fremstilling deraf
DE60230266D1 (de)	2009-01-22	Phenylpyridincarbonyl piperazinderivate
NO20081074L (no)	2008-04-29	Macrocyclisk inhibitorer av hepatitis C-virus
NO20062370L (no)	2006-07-18	Amidderivater
DK1585739T3 (da)	2011-06-20	Substituerede arylcyclopropylacetamider som glucokinaseaktivatorer
NO20092279L (no)	2009-08-31	Makrocyklisk factor VIIa inhibitorer anvendbare som antikoagulanter
HRP20070430T3 (en)	2007-11-30	(3-oxo-3,4-dihydro-quinoxalin-2-yl-amino)-benzamide derivatives and related compounds as glycogen phosphorylase inhibitors for the treatment of diabetes and obesity
NO20063761L (no)	2006-10-23	Sulfonamidderivater for behandling av sykdommer
NO20070605L (no)	2007-02-01	Nye 2-substituerte D-homoostra-1,3,5(10)-triener som inhibitor av 17(3-hydroksysteroiddehydrogenaser type-1.
NO20083390L (no)	2008-10-14	Piperaziner og piperidiner som mGluR5-forsterkere
NO20071008L (no)	2007-02-21	Fremgangsmate for fremstilling av N-piperidino-1,5-difenylpyrazol-3-karboksamidderivater
MY130411A (en)	2007-06-29	Piperidine derivatives
AR045959A1 (es)	2005-11-16	Derivados de pirazolo- e imidazo-pirimidina
NO20063647L (no)	2006-10-19	Nye inhibitorer av chymase
NO20052074L (no)	2005-06-01	Substituerte benzoksazinoner og anvendelser derav.
NO20054135L (no)	2005-09-23	Kipolinon/benzoksazin derivater og anvendelser derav
WO2008146919A1 (fr)	2008-12-04	Dérivé de la lincosamide et agent antibactérien le comprenant en tant qu'ingrédient actif
NO20062491L (no)	2006-09-06	Benzoksazinderivter og deres anvendelse
NO20082226L (no)	2008-07-01	6-heteroarylpyridoindolonderivater, deres fremstilling og terapeutisk anvendelse derav