NO20051663L - Fremgangsmater for behandling av neurodegenerasjon - Google Patents
Fremgangsmater for behandling av neurodegenerasjonInfo
- Publication number
- NO20051663L NO20051663L NO20051663A NO20051663A NO20051663L NO 20051663 L NO20051663 L NO 20051663L NO 20051663 A NO20051663 A NO 20051663A NO 20051663 A NO20051663 A NO 20051663A NO 20051663 L NO20051663 L NO 20051663L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- treating neurodegeneration
- disease
- alpha
- treating
- Prior art date
Links
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 230000007850 degeneration Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 230000000979 retarding effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Det beskrives fremgangsmåter for forhindring eller retardering av degenereringen av neuroner. Det beskrives også fremgangsmåter for behandling av Aizheimers sykdom eller Parkinsons sykdom gjennom administreringen av selektive alfa 2B eller alfa 2B/2C reseptoragonister.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41704902P | 2002-10-08 | 2002-10-08 | |
| PCT/US2003/031809 WO2004032913A1 (en) | 2002-10-08 | 2003-10-07 | Alpha 2b 0r 2b/2c adrenoceptor agonists for the treatment of neurodegeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20051663L true NO20051663L (no) | 2005-05-31 |
Family
ID=32093954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20051663A NO20051663L (no) | 2002-10-08 | 2005-04-04 | Fremgangsmater for behandling av neurodegenerasjon |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20040138312A1 (no) |
| EP (1) | EP1549305B1 (no) |
| JP (2) | JP4724421B2 (no) |
| KR (1) | KR20050050124A (no) |
| CN (1) | CN100431536C (no) |
| AT (1) | ATE429216T1 (no) |
| AU (2) | AU2003282758A1 (no) |
| BR (1) | BR0314540A (no) |
| CA (1) | CA2501347A1 (no) |
| DE (1) | DE60327335D1 (no) |
| ES (1) | ES2322954T3 (no) |
| IL (1) | IL167849A (no) |
| MX (1) | MXPA05003664A (no) |
| NO (1) | NO20051663L (no) |
| NZ (1) | NZ539328A (no) |
| PL (1) | PL216373B1 (no) |
| RU (1) | RU2330649C2 (no) |
| WO (1) | WO2004032913A1 (no) |
| ZA (1) | ZA200502744B (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007105203A2 (en) * | 2006-03-16 | 2007-09-20 | Yeda Research And Development Co. Ltd. | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels |
| US20110160265A1 (en) * | 2007-10-18 | 2011-06-30 | Luhrs Lauren M B | Method of treating motor disorders with alpha-2b adrenergic receptor agonists |
| US8455548B2 (en) | 2007-10-18 | 2013-06-04 | Allergan, Inc. | Method of treating sensorimotor disorders with alpha-2 adrenergic receptor agonists |
| WO2009052072A1 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Treating motor disorders with 4-(1-(2,3-dimethylphenyl)ethyl)-1h-imidazole-2(3h)-thione |
| ES2495099T3 (es) * | 2008-12-08 | 2014-09-16 | Allergan, Inc. | Compuestos de N-(1-fenil-2-ariletil)-4,5-dihidro-3H-pirrol-2-amina como moduladores selectivos de subtipo de los adrenoceptores alfa2B o alfa2B y alfa2C |
| CN110337290A (zh) | 2016-12-31 | 2019-10-15 | 比奥克斯塞尔医疗股份有限公司 | 舌下右旋美托咪啶用于治疗激越的用途 |
| EP4523752A3 (en) | 2018-06-27 | 2025-05-14 | BioXcel Therapeutics, Inc. | Film formulations containing dexmedetomidine and methods of producing them |
| JP7739256B2 (ja) | 2019-07-19 | 2025-09-16 | バイオエクセル セラピューティクス,インコーポレイテッド | 鎮静作用のないデクスメデトミジン治療レジメン |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029792A (en) * | 1972-02-29 | 1977-06-14 | Pfizer Inc. | (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents |
| BE795970A (fr) * | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
| US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
| US6194415B1 (en) * | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
| US6329369B1 (en) * | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
| US6841684B2 (en) * | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
| PT1036065E (pt) * | 1997-12-04 | 2004-09-30 | Allergan Inc | Derivados de imidazol substituidos com actividade do tipo agonista nos receptores alfa 2b ou 2b/2c adrenergicos |
| US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
| WO2002005853A2 (en) * | 2000-07-14 | 2002-01-24 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
| WO2002058730A2 (en) * | 2000-11-01 | 2002-08-01 | Allergan, Inc. | Compositions for treatment of ocular neovascularization |
| US7091232B2 (en) * | 2002-05-21 | 2006-08-15 | Allergan, Inc. | 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds |
-
2003
- 2003-10-07 WO PCT/US2003/031809 patent/WO2004032913A1/en not_active Ceased
- 2003-10-07 DE DE60327335T patent/DE60327335D1/de not_active Expired - Lifetime
- 2003-10-07 ES ES03774642T patent/ES2322954T3/es not_active Expired - Lifetime
- 2003-10-07 KR KR1020057006114A patent/KR20050050124A/ko not_active Abandoned
- 2003-10-07 PL PL376346A patent/PL216373B1/pl unknown
- 2003-10-07 US US10/680,879 patent/US20040138312A1/en not_active Abandoned
- 2003-10-07 EP EP03774642A patent/EP1549305B1/en not_active Expired - Lifetime
- 2003-10-07 NZ NZ539328A patent/NZ539328A/en not_active IP Right Cessation
- 2003-10-07 CN CNB200380101115XA patent/CN100431536C/zh not_active Expired - Fee Related
- 2003-10-07 CA CA002501347A patent/CA2501347A1/en not_active Abandoned
- 2003-10-07 BR BR0314540-9A patent/BR0314540A/pt not_active Application Discontinuation
- 2003-10-07 MX MXPA05003664A patent/MXPA05003664A/es active IP Right Grant
- 2003-10-07 JP JP2004543495A patent/JP4724421B2/ja not_active Expired - Fee Related
- 2003-10-07 RU RU2005114504/14A patent/RU2330649C2/ru not_active IP Right Cessation
- 2003-10-07 AU AU2003282758A patent/AU2003282758A1/en not_active Abandoned
- 2003-10-07 AT AT03774642T patent/ATE429216T1/de not_active IP Right Cessation
-
2005
- 2005-04-04 IL IL167849A patent/IL167849A/en active IP Right Grant
- 2005-04-04 NO NO20051663A patent/NO20051663L/no unknown
- 2005-04-05 ZA ZA200502744A patent/ZA200502744B/en unknown
-
2009
- 2009-11-20 AU AU2009238370A patent/AU2009238370B2/en not_active Ceased
-
2010
- 2010-12-03 JP JP2010270724A patent/JP2011057700A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN100431536C (zh) | 2008-11-12 |
| DE60327335D1 (de) | 2009-06-04 |
| ZA200502744B (en) | 2006-02-22 |
| WO2004032913A1 (en) | 2004-04-22 |
| AU2009238370A1 (en) | 2009-12-17 |
| NZ539328A (en) | 2007-01-26 |
| PL216373B1 (pl) | 2014-03-31 |
| ES2322954T3 (es) | 2009-07-02 |
| EP1549305B1 (en) | 2009-04-22 |
| US20040138312A1 (en) | 2004-07-15 |
| PL376346A1 (en) | 2005-12-27 |
| JP2011057700A (ja) | 2011-03-24 |
| EP1549305A1 (en) | 2005-07-06 |
| BR0314540A (pt) | 2005-07-26 |
| AU2003282758A1 (en) | 2004-05-04 |
| AU2009238370B2 (en) | 2011-07-21 |
| HK1081880A1 (zh) | 2006-05-26 |
| IL167849A (en) | 2011-04-28 |
| JP4724421B2 (ja) | 2011-07-13 |
| JP2006504739A (ja) | 2006-02-09 |
| CN1703213A (zh) | 2005-11-30 |
| RU2330649C2 (ru) | 2008-08-10 |
| CA2501347A1 (en) | 2004-04-22 |
| RU2005114504A (ru) | 2005-10-27 |
| MXPA05003664A (es) | 2005-06-08 |
| KR20050050124A (ko) | 2005-05-27 |
| ATE429216T1 (de) | 2009-05-15 |
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