NO20055495L - 4-(4-trans-hydroksysykloheksyl)amino-2-fenyl-7H-pyrrolo[2,3-d]-pyrimidinhydrogenmesylat og dets polymorfe former - Google Patents

4-(4-trans-hydroksysykloheksyl)amino-2-fenyl-7H-pyrrolo[2,3-d]-pyrimidinhydrogenmesylat og dets polymorfe former

Info

Publication number: NO20055495L
Authority: NO; Norway
Prior art keywords: pyrrolo; trans; phenyl; amino; cyclohexyl
Prior art date: 2003-04-22

Application number

NO20055495A

Other languages

English (en)

Norwegian (no)

Other versions

NO20055495D0 (no

Inventor

Emil Finner

Timo Heinrich

Axel Pahl

Bernd-Martin Luitjens

Pieter C Verveer

Jan Zorgdrager

Original Assignee

Solvay Pharm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-22

Filing date

2005-11-21

Publication date

2006-01-23

2005-11-21 Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh

2005-11-21 Publication of NO20055495D0 publication Critical patent/NO20055495D0/no

2006-01-23 Publication of NO20055495L publication Critical patent/NO20055495L/no

Links

ZBTPHDQFPPDXPK-UHFFFAOYSA-N S(C)(=O)(=O)O.NC=1C2=C(N=C(N1)C1=CC=CC=C1)NC=C2 Chemical compound S(C)(=O)(=O)O.NC=1C2=C(N=C(N1)C1=CC=CC=C1)NC=C2 ZBTPHDQFPPDXPK-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO20055495A 2003-04-22 2005-11-21 4-(4-trans-hydroksysykloheksyl)amino-2-fenyl-7H-pyrrolo[2,3-d]-pyrimidinhydrogenmesylat og dets polymorfe former NO20055495L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US46442203P	2003-04-22	2003-04-22
EP03101093		2003-04-22
PCT/EP2004/050573 WO2004094428A1 (en)	2003-04-22	2004-04-21	4-(4-trans-hydroxycyclohexyl)amino-2-phenyl-7h-pyrrolo`2, 3d! pyrimidine hydrogen mesylate and its polymorphic forms

Publications (2)

Publication Number	Publication Date
NO20055495D0 NO20055495D0 (no)	2005-11-21
NO20055495L true NO20055495L (no)	2006-01-23

Family

ID=36143550

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20055495A NO20055495L (no)	2003-04-22	2005-11-21	4-(4-trans-hydroksysykloheksyl)amino-2-fenyl-7H-pyrrolo[2,3-d]-pyrimidinhydrogenmesylat og dets polymorfe former

Country Status (25)

Country	Link
US (1)	US7381729B2 (de)
EP (1)	EP1641797B1 (de)
JP (1)	JP2006524214A (de)
KR (1)	KR20060021296A (de)
CN (1)	CN100360533C (de)
AR (1)	AR043880A1 (de)
AT (1)	ATE373002T1 (de)
AU (1)	AU2004232495B2 (de)
BR (1)	BRPI0409511A (de)
CA (1)	CA2522810A1 (de)
DE (1)	DE602004008919T2 (de)
DK (1)	DK1641797T3 (de)
ES (1)	ES2290696T3 (de)
IL (1)	IL171120A (de)
MX (1)	MXPA05011348A (de)
NO (1)	NO20055495L (de)
PL (1)	PL1641797T3 (de)
PT (1)	PT1641797E (de)
RU (1)	RU2345994C2 (de)
SA (1)	SA04250093B1 (de)
SI (1)	SI1641797T1 (de)
TW (1)	TWI324517B (de)
UA (1)	UA81806C2 (de)
WO (1)	WO2004094428A1 (de)
ZA (1)	ZA200508519B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR043880A1 (es)	2003-04-22	2005-08-17	Solvay Pharm Gmbh	Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
WO2007073855A1 (en) *	2005-12-23	2007-07-05	Bayer Healthcare Ag	Use of adenosine a1 receptor agonists for the protection of renal cells against toxic effects caused by aminoglycosides during treatment of infectious diseases
TW200808819A (en) *	2006-06-19	2008-02-16	Solvay Pharm Gmbh	Use of adenosine A1 antagonists in radiocontrast media induced nephrophaty
CN103724339B (zh)	2012-09-27	2015-10-14	广东东阳光药业有限公司	二氢嘧啶衍生物的晶型

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE55646B1 (en) *	1982-08-19	1990-12-05	Warner Lambert Co	3-deazaguanine sulfonic acid salts
CS249455B1 (en) *	1985-01-24	1987-03-12	Miroslav Protiva	N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation
JP2815691B2 (ja) *	1990-09-20	1998-10-27	麒麟麦酒株式会社	Ｋｒｎ２３９１酸付加塩およびその用途
BR9307646A (pt) *	1992-12-17	1999-05-25	Pfizer	Pirrolopirimidinas como antagonistas de crf
FR2708604B1 (fr) *	1993-07-30	1995-10-20	Sanofi Elf	Utilisation de dérivés de benzènesulfonyl-indole pour la préparation de médicaments.
JPH08198876A (ja) *	1995-01-30	1996-08-06	Yoshitomi Pharmaceut Ind Ltd	トランス−Ｎ−（１Ｈ−ピラゾロ〔３，４−ｂ〕ピリジン−４−イル）−４−グアニジノメチルシクロヘキサンカルボキサミド・１メタンスルホン酸塩・１水和物
JPH08337584A (ja) *	1995-04-10	1996-12-24	Dai Ichi Seiyaku Co Ltd	縮合六環式アミノ化合物、これを含有する医薬及びその製法
FR2749846B1 (fr) *	1996-06-17	1998-09-11	Pf Medicament	Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
MA24500A1 (fr) *	1997-03-21	1998-10-01	Lg Life Sciences Ltd	Derive du sel d'acide carboxylique de naphthyridine .
HUP0103836A3 (en) *	1998-06-02	2003-05-28	Osi Pharmaceuticals Inc Uniond	Pyrrolo[2,3d]pyrimidine compositions and their use
US6878716B1 (en) *	1998-06-02	2005-04-12	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine A1 receptor and uses thereof
TWI223598B (en) *	1998-06-22	2004-11-11	Pfizer Ireland Pharmaceuticals	An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate
ES2269217T3 (es) *	1999-12-02	2007-04-01	Osi Pharmaceuticals, Inc.	Compuestos especificos para los receptores a1, a2a y a3 de adenosina y sus usos.
AU779118B2 (en) *	2000-03-03	2005-01-06	Pfizer Inc.	4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3, 4-tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline mesylate and polymorphs
US6960590B2 (en) *	2000-10-17	2005-11-01	Merck & Co. Inc.	Orally active salts with tyrosine kinase activity
US6680324B2 (en) *	2000-12-01	2004-01-20	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine A1 receptors and uses thereof
US6673802B2 (en) *	2000-12-01	2004-01-06	Osi Pharmaceuticals, Inc.	Compounds specific to adenosine A3 receptor and uses thereof
AR043880A1 (es)	2003-04-22	2005-08-17	Solvay Pharm Gmbh	Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas

2004
- 2004-04-19 AR ARP040101306A patent/AR043880A1/es unknown
- 2004-04-20 TW TW093110973A patent/TWI324517B/zh not_active IP Right Cessation
- 2004-04-21 PT PT04728571T patent/PT1641797E/pt unknown
- 2004-04-21 UA UAA200511088A patent/UA81806C2/uk unknown
- 2004-04-21 WO PCT/EP2004/050573 patent/WO2004094428A1/en not_active Ceased
- 2004-04-21 ES ES04728571T patent/ES2290696T3/es not_active Expired - Lifetime
- 2004-04-21 MX MXPA05011348A patent/MXPA05011348A/es active IP Right Grant
- 2004-04-21 US US10/828,650 patent/US7381729B2/en not_active Expired - Fee Related
- 2004-04-21 CA CA002522810A patent/CA2522810A1/en not_active Abandoned
- 2004-04-21 CN CNB2004800106903A patent/CN100360533C/zh not_active Expired - Fee Related
- 2004-04-21 PL PL04728571T patent/PL1641797T3/pl unknown
- 2004-04-21 RU RU2005136215/04A patent/RU2345994C2/ru not_active IP Right Cessation
- 2004-04-21 EP EP04728571A patent/EP1641797B1/de not_active Expired - Lifetime
- 2004-04-21 AU AU2004232495A patent/AU2004232495B2/en not_active Ceased
- 2004-04-21 DE DE602004008919T patent/DE602004008919T2/de not_active Expired - Lifetime
- 2004-04-21 BR BRPI0409511-1A patent/BRPI0409511A/pt not_active IP Right Cessation
- 2004-04-21 KR KR1020057019944A patent/KR20060021296A/ko not_active Ceased
- 2004-04-21 SI SI200430470T patent/SI1641797T1/sl unknown
- 2004-04-21 JP JP2006505565A patent/JP2006524214A/ja active Pending
- 2004-04-21 DK DK04728571T patent/DK1641797T3/da active
- 2004-04-21 AT AT04728571T patent/ATE373002T1/de active
- 2004-04-22 SA SA4250093A patent/SA04250093B1/ar unknown
2005
- 2005-09-27 IL IL171120A patent/IL171120A/en not_active IP Right Cessation
- 2005-10-20 ZA ZA200508519A patent/ZA200508519B/en unknown
- 2005-11-21 NO NO20055495A patent/NO20055495L/no unknown

Also Published As

Publication number	Publication date
HK1089767A1 (en)	2006-12-08
ZA200508519B (en)	2007-04-25
TW200505457A (en)	2005-02-16
AU2004232495A1 (en)	2004-11-04
PT1641797E (pt)	2007-12-21
EP1641797A1 (de)	2006-04-05
RU2005136215A (ru)	2006-03-20
AR043880A1 (es)	2005-08-17
CA2522810A1 (en)	2004-11-04
AU2004232495B2 (en)	2010-04-22
EP1641797B1 (de)	2007-09-12
DE602004008919D1 (de)	2007-10-25
UA81806C2 (uk)	2008-02-11
CN1777606A (zh)	2006-05-24
NO20055495D0 (no)	2005-11-21
US7381729B2 (en)	2008-06-03
TWI324517B (en)	2010-05-11
US20040248912A1 (en)	2004-12-09
KR20060021296A (ko)	2006-03-07
SA04250093B1 (ar)	2008-07-12
ATE373002T1 (de)	2007-09-15
DK1641797T3 (da)	2007-10-29
DE602004008919T2 (de)	2008-06-19
JP2006524214A (ja)	2006-10-26
ES2290696T3 (es)	2008-02-16
CN100360533C (zh)	2008-01-09
PL1641797T3 (pl)	2008-01-31
BRPI0409511A (pt)	2006-04-18
SI1641797T1 (sl)	2007-12-31
MXPA05011348A (es)	2005-11-28
WO2004094428A1 (en)	2004-11-04
RU2345994C2 (ru)	2009-02-10
IL171120A (en)	2011-01-31

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