NO20060145L - Substituerte indazolyl (indolyl) maleimidderivater som kinase inhibitorer - Google Patents

Substituerte indazolyl (indolyl) maleimidderivater som kinase inhibitorer

Info

Publication number: NO20060145L
Authority: NO; Norway
Prior art keywords: sub; kinase inhibitors; kinase; indolyl; compounds
Prior art date: 2003-06-13

Application number

NO20060145A

Other languages

English (en)

Norwegian (no)

Inventor

Bruce E Maryanoff

Han-Cheng Zhang

Hong Ye

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-13

Filing date

2006-01-10

Publication date

2006-03-07

2006-01-10 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2006-03-07 Publication of NO20060145L publication Critical patent/NO20060145L/no

Links

229940043355 kinase inhibitor Drugs 0.000 title abstract 2
IBDXJDUQTQCJOV-UHFFFAOYSA-N 3-(1H-indazol-3-yl)-4-(1H-indol-2-yl)pyrrole-2,5-dione Chemical class C1=CC=C2C(C=3C(=O)NC(C=3C=3NC4=CC=CC=C4C=3)=O)=NNC2=C1 IBDXJDUQTQCJOV-UHFFFAOYSA-N 0.000 title 1
239000003757 phosphotransferase inhibitor Substances 0.000 title 1
108091000080 Phosphotransferase Proteins 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
102000020233 phosphotransferase Human genes 0.000 abstract 2
229940127263 dual kinase inhibitor Drugs 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
-1 indazolyl-substituted pyrroline compounds Chemical class 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Virology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Transplantation (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Ophthalmology & Optometry (AREA)

NO20060145A 2003-06-13 2006-01-10 Substituerte indazolyl (indolyl) maleimidderivater som kinase inhibitorer NO20060145L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US47851603P	2003-06-13	2003-06-13
PCT/US2004/017375 WO2005000836A1 (en)	2003-06-13	2004-06-01	Substituted indazolyl(indolyl)maleimide derivatives as kinase inhibitors

Publications (1)

Publication Number	Publication Date
NO20060145L true NO20060145L (no)	2006-03-07

Family

ID=33551833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20060145A NO20060145L (no)	2003-06-13	2006-01-10	Substituerte indazolyl (indolyl) maleimidderivater som kinase inhibitorer

Country Status (22)

Country	Link
US (1)	US7439363B2 (pt)
EP (1)	EP1654255B1 (pt)
JP (1)	JP2007500748A (pt)
KR (1)	KR20060021890A (pt)
CN (1)	CN1832940A (pt)
AT (1)	ATE406365T1 (pt)
AU (1)	AU2004251178A1 (pt)
BR (1)	BRPI0411366A (pt)
CA (1)	CA2529353A1 (pt)
CO (1)	CO5650246A2 (pt)
CR (1)	CR8148A (pt)
DE (1)	DE602004016174D1 (pt)
EA (1)	EA200600032A1 (pt)
EC (1)	ECSP056222A (pt)
ES (1)	ES2311161T3 (pt)
HR (1)	HRP20050991A2 (pt)
IL (1)	IL172456A0 (pt)
IS (1)	IS8174A (pt)
NO (1)	NO20060145L (pt)
RS (1)	RS20050915A (pt)
WO (1)	WO2005000836A1 (pt)
ZA (1)	ZA200600294B (pt)

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WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
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US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
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WO2003095452A1 (en) *	2002-05-08	2003-11-20	Janssen Pharmaceutica N.V.	Substituted pyrroline kinase inhibitors
EP1513520B1 (en) *	2002-06-05	2008-09-24	Janssen Pharmaceutica N.V.	Substituted pyrrolines as kinase inhibitors
JP2005531609A (ja) *	2002-06-05	2005-10-20	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	キナーゼ阻害剤としてのシスインドリル−マレイミド誘導体
US7488826B2 (en) *	2003-03-27	2009-02-10	Janssen Pharmaceutica N.V.	Substituted pyrroline kinase inhibitors

2004
- 2004-06-01 HR HR20050991A patent/HRP20050991A2/xx not_active Application Discontinuation
- 2004-06-01 EA EA200600032A patent/EA200600032A1/ru unknown
- 2004-06-01 CN CNA200480022892XA patent/CN1832940A/zh active Pending
- 2004-06-01 ES ES04754066T patent/ES2311161T3/es not_active Expired - Lifetime
- 2004-06-01 AU AU2004251178A patent/AU2004251178A1/en not_active Abandoned
- 2004-06-01 WO PCT/US2004/017375 patent/WO2005000836A1/en not_active Ceased
- 2004-06-01 KR KR1020057023946A patent/KR20060021890A/ko not_active Withdrawn
- 2004-06-01 JP JP2006533550A patent/JP2007500748A/ja not_active Withdrawn
- 2004-06-01 DE DE602004016174T patent/DE602004016174D1/de not_active Expired - Fee Related
- 2004-06-01 BR BRPI0411366-7A patent/BRPI0411366A/pt not_active IP Right Cessation
- 2004-06-01 RS YUP-2005/0915A patent/RS20050915A/sr unknown
- 2004-06-01 EP EP04754066A patent/EP1654255B1/en not_active Expired - Lifetime
- 2004-06-01 CA CA002529353A patent/CA2529353A1/en not_active Abandoned
- 2004-06-01 AT AT04754066T patent/ATE406365T1/de not_active IP Right Cessation
- 2004-06-01 US US10/858,212 patent/US7439363B2/en not_active Expired - Fee Related
2005
- 2005-12-08 IL IL172456A patent/IL172456A0/en unknown
- 2005-12-09 IS IS8174A patent/IS8174A/is unknown
- 2005-12-13 EC EC2005006222A patent/ECSP056222A/es unknown
- 2005-12-13 CR CR8148A patent/CR8148A/es not_active Application Discontinuation
- 2005-12-19 CO CO05127381A patent/CO5650246A2/es not_active Application Discontinuation
2006
- 2006-01-10 NO NO20060145A patent/NO20060145L/no not_active Application Discontinuation
- 2006-01-12 ZA ZA200600294A patent/ZA200600294B/xx unknown

Also Published As

Publication number	Publication date
CN1832940A (zh)	2006-09-13
JP2007500748A (ja)	2007-01-18
KR20060021890A (ko)	2006-03-08
EP1654255B1 (en)	2008-08-27
RS20050915A (sr)	2008-04-04
AU2004251178A1 (en)	2005-01-06
ES2311161T3 (es)	2009-02-01
ECSP056222A (es)	2006-04-19
CR8148A (es)	2008-09-10
EP1654255A1 (en)	2006-05-10
US20050004201A1 (en)	2005-01-06
EA200600032A1 (ru)	2006-06-30
ATE406365T1 (de)	2008-09-15
ZA200600294B (en)	2007-04-25
CA2529353A1 (en)	2005-01-06
WO2005000836A1 (en)	2005-01-06
IL172456A0 (en)	2006-04-10
CO5650246A2 (es)	2006-06-30
BRPI0411366A (pt)	2006-07-25
US7439363B2 (en)	2008-10-21
IS8174A (is)	2005-12-09
HRP20050991A2 (en)	2006-09-30
DE602004016174D1 (de)	2008-10-09

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Date	Code	Title	Description
2010-01-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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