NO20060231L - Difenylureaderivater og deres anvendelse som kloridkanalblokkere - Google Patents

Difenylureaderivater og deres anvendelse som kloridkanalblokkere

Info

Publication number
NO20060231L
NO20060231L NO20060231A NO20060231A NO20060231L NO 20060231 L NO20060231 L NO 20060231L NO 20060231 A NO20060231 A NO 20060231A NO 20060231 A NO20060231 A NO 20060231A NO 20060231 L NO20060231 L NO 20060231L
Authority
NO
Norway
Prior art keywords
channel blockers
chloride channel
diphenylurea derivatives
derivatives
diphenylurea
Prior art date
Application number
NO20060231A
Other languages
English (en)
Inventor
Palle Christophersen
Bjarne H Dahl
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of NO20060231L publication Critical patent/NO20060231L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Den foreliggende oppfinnelse vedrører nye difenylureaderivater som kan anvendes som kloridkanalblokkere. Ved andre aspekter vedrører oppfinnelsen anvendelsen av disse forbindelsene ved en fremgangsmåte for terapi, og farmasøytiske preparater som omfatter forbindelsene ifølge oppfinnelsen.
NO20060231A 2003-06-17 2006-01-16 Difenylureaderivater og deres anvendelse som kloridkanalblokkere NO20060231L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200300898 2003-06-17
PCT/EP2004/051111 WO2004111017A1 (en) 2003-06-17 2004-06-15 Diphenylurea derivatives and their use as chloride channel blockers

Publications (1)

Publication Number Publication Date
NO20060231L true NO20060231L (no) 2006-01-16

Family

ID=33547538

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060231A NO20060231L (no) 2003-06-17 2006-01-16 Difenylureaderivater og deres anvendelse som kloridkanalblokkere

Country Status (19)

Country Link
US (1) US7691891B2 (no)
EP (1) EP1638948B1 (no)
JP (1) JP2006527735A (no)
KR (1) KR20060059901A (no)
CN (1) CN1805942B (no)
AT (1) ATE411301T1 (no)
AU (1) AU2004247429B2 (no)
BR (1) BRPI0410576A (no)
CA (1) CA2529806A1 (no)
DE (1) DE602004017175D1 (no)
DK (1) DK1638948T3 (no)
IS (1) IS8211A (no)
MX (1) MXPA05013269A (no)
NO (1) NO20060231L (no)
NZ (1) NZ543595A (no)
RU (1) RU2350607C2 (no)
UA (1) UA81664C2 (no)
WO (1) WO2004111017A1 (no)
ZA (1) ZA200508828B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008524158A (ja) * 2004-12-17 2008-07-10 ノイロサーチ アクティーゼルスカブ カリウムチャネル活性化剤として有用なジフェニル尿素誘導体
WO2007104719A1 (en) * 2006-03-14 2007-09-20 Neurosearch A/S Diphenylurea derivatives and their use as chloride channel blockers or bkca channel modulators
US20100292283A1 (en) * 2007-11-28 2010-11-18 Antonio Nardi Novel phenyl-acetamide and phenyl-propionamide derivatives useful as potassium channel modulators
US9834537B2 (en) 2013-11-27 2017-12-05 Korea Institute Of Science And Technology Compounds as chloride channel blocking agent
SI3458052T1 (sl) 2016-05-17 2020-04-30 Scandion Oncology A/S Kombinirano zdravljenje raka
CN117229258B (zh) * 2022-06-07 2024-07-19 杭州壹瑞医药科技有限公司 N-四唑基芳基脲类衍生物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4073489B2 (ja) * 1996-05-24 2008-04-09 ニューロサーチ・アクティーゼルスカブ 酸性基を有するフエニル誘導体、その製造方法及びそれをクロライドチャンネル遮断剤として使用する方法
CN1118462C (zh) * 1997-04-22 2003-08-20 神经研究公司 取代的苯基衍生物、其制备方法以及用途
US6696475B2 (en) 1997-04-22 2004-02-24 Neurosearch A/S Substituted phenyl derivatives, their preparation and use
AU5727899A (en) 1998-10-02 2000-04-26 Neurosearch A/S Diaminocyclobutene-3,4-dione derivatives, their preparation and use
SK5222001A3 (en) * 1998-10-22 2002-05-09 Neurosearch As Substituted phenyl derivatives, their preparation and use
WO2002039987A2 (en) * 2000-11-14 2002-05-23 Neurosearch A/S Use of malaria parasite anion channel blockers for treating malaria
WO2003000245A1 (en) * 2001-06-22 2003-01-03 Poseidon Pharmaceuticals A/S Compounds for use in disorders associated with mast cell or basophil activity
ATE372770T1 (de) * 2002-08-01 2007-09-15 Neurosearch As Verbindungen nützlich in der behandlung von erkrankungen die auf anti-angiogenertherapie antworten
EP1537075B1 (en) * 2002-09-05 2009-07-01 Neurosearch A/S Diarylurea derivatives and their use as chloride channel blockers
JP2008524158A (ja) * 2004-12-17 2008-07-10 ノイロサーチ アクティーゼルスカブ カリウムチャネル活性化剤として有用なジフェニル尿素誘導体

Also Published As

Publication number Publication date
EP1638948B1 (en) 2008-10-15
RU2350607C2 (ru) 2009-03-27
MXPA05013269A (es) 2006-03-17
ZA200508828B (en) 2008-01-30
KR20060059901A (ko) 2006-06-02
CA2529806A1 (en) 2004-12-23
CN1805942A (zh) 2006-07-19
ATE411301T1 (de) 2008-10-15
DK1638948T3 (da) 2009-02-02
EP1638948A1 (en) 2006-03-29
NZ543595A (en) 2009-01-31
JP2006527735A (ja) 2006-12-07
RU2005136532A (ru) 2006-07-27
HK1091816A1 (zh) 2007-01-26
UA81664C2 (ru) 2008-01-25
US7691891B2 (en) 2010-04-06
DE602004017175D1 (de) 2008-11-27
CN1805942B (zh) 2010-06-02
BRPI0410576A (pt) 2006-06-20
AU2004247429B2 (en) 2010-01-28
AU2004247429A1 (en) 2004-12-23
WO2004111017A1 (en) 2004-12-23
US20060178413A1 (en) 2006-08-10
IS8211A (is) 2005-12-30

Similar Documents

Publication Publication Date Title
NO20073791L (no) Pyrazolylaminopyridinderivater anvendbare som kinaseinhibitorer
NO20064763L (no) Forbindelser og fremgangsmater for behandling av dyslipidemi
EA200870391A1 (ru) Тетрагидропирролопиримидиндионы и их применение в качестве ингибиторов эластазы нейтрофилов человека
ATE484508T1 (de) Furylverbindungen
EA201200669A1 (ru) ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα
NO20064976L (no) Azanidoler som er nyttige som inhibitorer av rock og andre proteinkinaser
EA200700096A1 (ru) Производные 2-карбамид-4-фенилтиазола, способ их получения и их применение в терапии
NO20054905L (no) 2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika
EA200800760A1 (ru) ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα
NO20090628L (no) Pyridizinon derivativater
NO20071549L (no) Nye benzofuserte heteroalrylsulfamidderivater, anvendelige som anti-krampemidler
EA200702674A1 (ru) Способ лечения атеросклероза, дислипидемий и связанных с ними состояний и фармацевтические композиции
NO20062649L (no) Biarylsulfonamider og metoder for anvendelse av disse
BRPI0716069A2 (pt) composto, composiÇço farmacÊutica, e, mÉtodo para tratar um distérbio
NO20080394L (no) N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav
NO20062021L (no) Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika
NO20054340L (no) Nye sammenkoplede heterocykler og deres anvendelse
NO20060360L (no) Nye 8-azabisyklo [3.2.1] oktanderivater og deres anvendelse som monoaminneurotransmittergjenopptaksinhibitorer
NO20083201L (no) Nye fenantridinderivater som bradykininantagonister
DK1606288T3 (da) Benzensulfonamidderivater, fremgangsmåde til fremstilling deraf og deres anvendelse til behandling af smerte
NO20073652L (no) Enantiomerer av 3-heteroaryl-8H-8-azabisyklo(3.2.1)okt-2-en og deres anvendelse som monoaminnevrotransmitter-gjenopptaksinhibitorer
DE60329326D1 (de) Tace inhibitoren
NO20084055L (no) Nye primaere aminer
ATE419242T1 (de) Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
NO20084279L (no) Difenylureaderivater og deres anvendelse som kloridkanalblokkere eller BKCa-kanalmodulatorer

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application