IS8211A - Dífenýlúrea-afleiður og notkun þeirra sem klórgangahindrar - Google Patents

Dífenýlúrea-afleiður og notkun þeirra sem klórgangahindrar

Info

Publication number
IS8211A
IS8211A IS8211A IS8211A IS8211A IS 8211 A IS8211 A IS 8211A IS 8211 A IS8211 A IS 8211A IS 8211 A IS8211 A IS 8211A IS 8211 A IS8211 A IS 8211A
Authority
IS
Iceland
Prior art keywords
diphenylurea derivatives
inhibitors
chlorine barrier
chlorine
barrier inhibitors
Prior art date
Application number
IS8211A
Other languages
English (en)
Inventor
H. Dahl Bjarne
Christophersen Palle
Original Assignee
Neurosearch A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch A/S filed Critical Neurosearch A/S
Publication of IS8211A publication Critical patent/IS8211A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS8211A 2003-06-17 2005-12-30 Dífenýlúrea-afleiður og notkun þeirra sem klórgangahindrar IS8211A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200300898 2003-06-17
PCT/EP2004/051111 WO2004111017A1 (en) 2003-06-17 2004-06-15 Diphenylurea derivatives and their use as chloride channel blockers

Publications (1)

Publication Number Publication Date
IS8211A true IS8211A (is) 2005-12-30

Family

ID=33547538

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8211A IS8211A (is) 2003-06-17 2005-12-30 Dífenýlúrea-afleiður og notkun þeirra sem klórgangahindrar

Country Status (19)

Country Link
US (1) US7691891B2 (is)
EP (1) EP1638948B1 (is)
JP (1) JP2006527735A (is)
KR (1) KR20060059901A (is)
CN (1) CN1805942B (is)
AT (1) ATE411301T1 (is)
AU (1) AU2004247429B2 (is)
BR (1) BRPI0410576A (is)
CA (1) CA2529806A1 (is)
DE (1) DE602004017175D1 (is)
DK (1) DK1638948T3 (is)
IS (1) IS8211A (is)
MX (1) MXPA05013269A (is)
NO (1) NO20060231L (is)
NZ (1) NZ543595A (is)
RU (1) RU2350607C2 (is)
UA (1) UA81664C2 (is)
WO (1) WO2004111017A1 (is)
ZA (1) ZA200508828B (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101287456A (zh) * 2004-12-17 2008-10-15 神经研究公司 用作钾通道激活剂的二苯基脲衍生物
MX2008011409A (es) * 2006-03-14 2008-09-22 Neurosearch As Derivados de difenilurea y su uso como bloqueadores de canal de cloruro o moduladores del canal bkca.
WO2009068557A1 (en) * 2007-11-28 2009-06-04 Neurosearch A/S Novel phenyl-acetamide and phenyl-propionamide derivatives useful as potassium channel modulators
US9834537B2 (en) 2013-11-27 2017-12-05 Korea Institute Of Science And Technology Compounds as chloride channel blocking agent
EP3622953B1 (en) 2016-05-17 2021-03-17 Scandion Oncology A/S Combination treatment of cancer
CN117229258B (zh) * 2022-06-07 2024-07-19 杭州壹瑞医药科技有限公司 N-四唑基芳基脲类衍生物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255858C (en) * 1996-05-24 2007-09-11 Neurosearch A/S Phenyl derivatives containing an acidic group, their preparation and their use as chloride channel blockers
US6696475B2 (en) * 1997-04-22 2004-02-24 Neurosearch A/S Substituted phenyl derivatives, their preparation and use
CZ295822B6 (cs) * 1997-04-22 2005-11-16 Neurosearch A/S Substituované fenylderiváty, způsob jejich přípravy a použití a farmaceutické přípravky s jejich obsahem
WO2000020378A1 (en) 1998-10-02 2000-04-13 Neurosearch A/S Diaminocyclobutene-3,4-dione derivatives, their preparation and use
CN1263733C (zh) 1998-10-22 2006-07-12 神经研究公司 取代苯基衍生物,它们的制备和用途
WO2002039987A2 (en) * 2000-11-14 2002-05-23 Neurosearch A/S Use of malaria parasite anion channel blockers for treating malaria
WO2003000245A1 (en) * 2001-06-22 2003-01-03 Poseidon Pharmaceuticals A/S Compounds for use in disorders associated with mast cell or basophil activity
JP2005537336A (ja) * 2002-08-01 2005-12-08 ニューロサーチ、アクティーゼルスカブ 抗血管新生治療に応答する疾患の治療に有用な化合物
EP1537075B1 (en) * 2002-09-05 2009-07-01 Neurosearch A/S Diarylurea derivatives and their use as chloride channel blockers
CN101287456A (zh) * 2004-12-17 2008-10-15 神经研究公司 用作钾通道激活剂的二苯基脲衍生物

Also Published As

Publication number Publication date
ATE411301T1 (de) 2008-10-15
RU2005136532A (ru) 2006-07-27
US20060178413A1 (en) 2006-08-10
ZA200508828B (en) 2008-01-30
DE602004017175D1 (de) 2008-11-27
RU2350607C2 (ru) 2009-03-27
EP1638948B1 (en) 2008-10-15
US7691891B2 (en) 2010-04-06
EP1638948A1 (en) 2006-03-29
AU2004247429B2 (en) 2010-01-28
NO20060231L (no) 2006-01-16
DK1638948T3 (da) 2009-02-02
CN1805942B (zh) 2010-06-02
CA2529806A1 (en) 2004-12-23
UA81664C2 (ru) 2008-01-25
AU2004247429A1 (en) 2004-12-23
JP2006527735A (ja) 2006-12-07
HK1091816A1 (zh) 2007-01-26
BRPI0410576A (pt) 2006-06-20
WO2004111017A1 (en) 2004-12-23
KR20060059901A (ko) 2006-06-02
NZ543595A (en) 2009-01-31
MXPA05013269A (es) 2006-03-17
CN1805942A (zh) 2006-07-19

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