NO20060985L - Inhibitorer av Akt aktivitet - Google Patents

Inhibitorer av Akt aktivitet

Info

Publication number
NO20060985L
NO20060985L NO20060985A NO20060985A NO20060985L NO 20060985 L NO20060985 L NO 20060985L NO 20060985 A NO20060985 A NO 20060985A NO 20060985 A NO20060985 A NO 20060985A NO 20060985 L NO20060985 L NO 20060985L
Authority
NO
Norway
Prior art keywords
inhibitors
akt activity
activity
compounds
akt
Prior art date
Application number
NO20060985A
Other languages
English (en)
Inventor
Jack Dale Leber
Dirk A Heerding
Tammy J Clark
David H Drewry
Igor Safonov
Dennis Yamashita
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20060985L publication Critical patent/NO20060985L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Oppfinnelsen angår nye lH-imidazo[4,5-c]pyridin-2-yl-forbindelser, anvendelsen av slike forbindelser som inhibitorer av proteinkinase B-aktivitet og i behandlingen av cancer og artritt.
NO20060985A 2003-07-29 2006-02-28 Inhibitorer av Akt aktivitet NO20060985L (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US49085103P 2003-07-29 2003-07-29
US49105503P 2003-07-30 2003-07-30
US49310103P 2003-08-06 2003-08-06
US49475203P 2003-08-13 2003-08-13
US50701403P 2003-09-29 2003-09-29
US53084703P 2003-12-18 2003-12-18
PCT/US2004/024340 WO2005011700A1 (en) 2003-07-29 2004-07-28 INHIBITORS OF Akt ACTIVITY

Publications (1)

Publication Number Publication Date
NO20060985L true NO20060985L (no) 2006-04-19

Family

ID=34120170

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060985A NO20060985L (no) 2003-07-29 2006-02-28 Inhibitorer av Akt aktivitet

Country Status (16)

Country Link
US (1) US20080255143A1 (no)
EP (1) EP1653961A4 (no)
JP (1) JP2007500709A (no)
KR (1) KR20060066714A (no)
AR (1) AR045134A1 (no)
AU (1) AU2004261214A1 (no)
BR (1) BRPI0412993A (no)
CA (1) CA2534038A1 (no)
CO (1) CO5640140A2 (no)
IL (1) IL173174A0 (no)
IS (1) IS8322A (no)
MA (1) MA27933A1 (no)
MX (1) MXPA06001134A (no)
NO (1) NO20060985L (no)
TW (1) TW200523262A (no)
WO (1) WO2005011700A1 (no)

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ES2387780T3 (es) * 2003-10-06 2012-10-01 Glaxosmithkline Llc Preparación de azabencimidazoles 1,6-disustituidos como inhibidores de quinasas
JP2007510667A (ja) * 2003-11-07 2007-04-26 スミスクライン ビーチャム （コーク） リミテッド 癌の治療法

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US20080255143A1 (en) 2008-10-16
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JP2007500709A (ja) 2007-01-18
IS8322A (is) 2006-02-22
AU2004261214A1 (en) 2005-02-10
AR045134A1 (es) 2005-10-19
CO5640140A2 (es) 2006-05-31
TW200523262A (en) 2005-07-16
BRPI0412993A (pt) 2006-10-03
WO2005011700A1 (en) 2005-02-10
EP1653961A4 (en) 2009-04-01
KR20060066714A (ko) 2006-06-16
EP1653961A1 (en) 2006-05-10
IL173174A0 (en) 2006-06-11
CA2534038A1 (en) 2005-02-10

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