NO20063716L - Anvendelse av lavdose erytropoietin ved stimulering av endotel forloperceller, regenerering av organer og sinking av progresjonen av sluttorganskader - Google Patents
Anvendelse av lavdose erytropoietin ved stimulering av endotel forloperceller, regenerering av organer og sinking av progresjonen av sluttorganskaderInfo
- Publication number
- NO20063716L NO20063716L NO20063716A NO20063716A NO20063716L NO 20063716 L NO20063716 L NO 20063716L NO 20063716 A NO20063716 A NO 20063716A NO 20063716 A NO20063716 A NO 20063716A NO 20063716 L NO20063716 L NO 20063716L
- Authority
- NO
- Norway
- Prior art keywords
- stimulation
- progenitor cells
- endothelial progenitor
- organ
- slowing
- Prior art date
Links
- 230000003511 endothelial effect Effects 0.000 title abstract 4
- 210000000130 stem cell Anatomy 0.000 title abstract 4
- 230000000638 stimulation Effects 0.000 title abstract 4
- 102000003951 Erythropoietin Human genes 0.000 title abstract 3
- 108090000394 Erythropoietin Proteins 0.000 title abstract 3
- 229940105423 erythropoietin Drugs 0.000 title abstract 3
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title abstract 3
- 230000033667 organ regeneration Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 230000004069 differentiation Effects 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000004862 vasculogenesis Effects 0.000 abstract 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Birds (AREA)
- Rheumatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
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- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
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Abstract
Foreliggende oppfinnelse vedrører anvendelsen av lavt dosert erytropoietin for stimulering av den fysiologiske mobiliseringen, proliferasjonen og differensieringen av endotel-forløperceller for stimulering av vaskulogenesen, for terapi av sykdommer som har en sammenheng med en dysfunksjon av endotel-forløperceller, og for fremstilling av farmasøytiske sammensetninger for behandling av slike sykdommer samt farmasøytiske sammensetninger som omfatter erytropoietin og andre egnede virkestoffer for stimulering av endotel-forløperceller.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004004509A DE102004004509B4 (de) | 2004-01-23 | 2004-01-23 | Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden |
| PCT/EP2005/000618 WO2005070450A2 (de) | 2004-01-23 | 2005-01-22 | Verwendung von niedrig dosiertem erythropoietin zur behandlung von akuter oder chronischer niereninsuffizienz und zur behandlung von wunden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20063716L true NO20063716L (no) | 2006-10-18 |
Family
ID=34801204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20063716A NO20063716L (no) | 2004-01-23 | 2006-08-18 | Anvendelse av lavdose erytropoietin ved stimulering av endotel forloperceller, regenerering av organer og sinking av progresjonen av sluttorganskader |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070161552A1 (no) |
| EP (2) | EP2156843A3 (no) |
| JP (2) | JP2007518769A (no) |
| KR (1) | KR20070007082A (no) |
| CN (2) | CN101601857A (no) |
| AU (2) | AU2005205917B2 (no) |
| BR (1) | BRPI0507048A (no) |
| CA (1) | CA2554234A1 (no) |
| DE (2) | DE102004063927A1 (no) |
| EA (3) | EA200900874A1 (no) |
| IL (2) | IL177017A0 (no) |
| NO (1) | NO20063716L (no) |
| NZ (1) | NZ548697A (no) |
| SG (1) | SG149875A1 (no) |
| UA (1) | UA86400C2 (no) |
| WO (1) | WO2005070450A2 (no) |
| ZA (1) | ZA200606515B (no) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10234192B4 (de) * | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| AR061269A1 (es) * | 2006-06-07 | 2008-08-13 | Chugai Pharmaceutical Co Ltd | Composicion y metodo de revascularizacion para el tratamiento de enfermedades isquemicas usando eritropoyetina |
| EP2018835B1 (de) | 2007-07-09 | 2014-03-05 | Augustinus Bader | Wirkstoff abgebendes Pflaster |
| JP5869219B2 (ja) * | 2007-08-16 | 2016-02-24 | レメドー バイオメッド リミテッド | 治療および美容適用のためのエリスロポイエチンおよびフィブロネクチン組成物 |
| US20100310626A1 (en) * | 2008-01-24 | 2010-12-09 | Remedor Biomed Ltd. | Erythropoietin and fibronectin compositions for bone regeneration |
| CN101980714A (zh) * | 2008-03-31 | 2011-02-23 | 奥古斯蒂努斯·巴德 | 借助干细胞或骨髓细胞进行组织再生的方法和组合物 |
| WO2011108711A1 (ja) * | 2010-03-04 | 2011-09-09 | 扶桑薬品工業株式会社 | 妊娠高血圧症候群モデル動物とその治療方法 |
| RU2426174C1 (ru) * | 2010-03-29 | 2011-08-10 | Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" | Способ фармакологической коррекции ишемии конечности, в том числе при l-name индуцированном дефиците оксида азота |
| EP2590666B1 (en) | 2010-07-06 | 2017-04-26 | Augustinus Bader | Topical application of erythropoietin for use in the treatment of injuries of the cornea |
| WO2012031778A1 (de) | 2010-09-12 | 2012-03-15 | Augustinus Bader | Verwendung von erythropoietin bei der heilung von wunden oder gewebedefekten ohne narbenbildung |
| WO2013057357A1 (es) * | 2011-10-21 | 2013-04-25 | Servicio Andaluz De Salud | Método para la identificación de fármacos útiles para el tratamiento de enfermedades cardiovasculares |
| WO2014160496A1 (en) * | 2013-03-13 | 2014-10-02 | Stemetrix, Inc. | Skin compositions and uses |
| WO2017104725A1 (ja) * | 2015-12-16 | 2017-06-22 | 第一三共株式会社 | 創傷治療剤 |
| JP7043784B2 (ja) * | 2016-10-28 | 2022-03-30 | 大正製薬株式会社 | 発毛剤 |
| CN108114282B (zh) * | 2016-11-28 | 2021-03-02 | 北京大学第三医院 | 他汀类化合物治疗缺血性疾病的用途 |
| CN106754650B (zh) * | 2017-02-24 | 2018-10-02 | 哈尔滨中科赛恩斯生物技术有限公司 | 一种骨髓来源的内皮祖细胞培养方法 |
| RU2720103C1 (ru) * | 2019-10-16 | 2020-04-24 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ коррекции нарушений микроциркуляции в плаценте карбамилированным дарбэпоэтином при ADMA-подобной модели преэклампсии |
| KR102387136B1 (ko) * | 2020-04-06 | 2022-04-14 | 재단법인대구경북과학기술원 | 탈모의 예방 또는 치료용 펩티드 및 이의 이용 |
| CN119080909A (zh) * | 2024-08-29 | 2024-12-06 | 深圳赛保尔生物药业有限公司 | 负载peg-epo及间充质干细胞的组合物、药物及其制备方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5455790A (en) | 1977-10-05 | 1979-05-04 | Tomoyuki Tajima | Production of erythropoetin |
| JPS6045849B2 (ja) | 1980-08-25 | 1985-10-12 | 林原 健 | ヒトエリトロポエチンの製造方法 |
| NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin |
| US5198417A (en) * | 1985-11-27 | 1993-03-30 | Genetics Institute, Inc. | Methods of treating pancytopenia and AIDS by co-administering EPO and colony stimulating factors |
| JPH03503167A (ja) * | 1988-02-24 | 1991-07-18 | アメリカン ナショナル レッド クロス | 部位指定血管形成素子とその使用法 |
| US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| HUT73876A (en) | 1993-04-29 | 1996-10-28 | Abbott Lab | Erythropoietin analog compositions and methods |
| CN1057534C (zh) | 1993-08-17 | 2000-10-18 | 柯瑞英-艾格公司 | 促红细胞生成素类似物 |
| EP0939644B1 (en) * | 1996-08-27 | 2004-01-14 | Hemosol Inc. | Enhanced stimulation of erythropoiesis |
| US20020052309A1 (en) * | 1996-09-11 | 2002-05-02 | Athanasius A. Anagnostou | Method of treating endothelial injury |
| US5980887A (en) * | 1996-11-08 | 1999-11-09 | St. Elizabeth's Medical Center Of Boston | Methods for enhancing angiogenesis with endothelial progenitor cells |
| RU2144815C1 (ru) * | 1996-12-24 | 2000-01-27 | Общество с ограниченной ответственностью Научно-производственный центр "Сибирская природная косметика" | Способ получения регенерирующего косметического крема для ухода за кожей |
| US6284260B1 (en) * | 1998-02-04 | 2001-09-04 | Veronica L. Zaharia Czeizler | Treatment with erythropoietin of bleeding from benign and malignant lesions with normal and abnormal coagulation parameters |
| EP0965349A1 (de) * | 1998-06-18 | 1999-12-22 | Roche Diagnostics GmbH | Verwendung von Erythropoietin zur Behandlung von Hämochromatosen |
| AR019025A1 (es) * | 1998-04-09 | 2001-12-26 | Roche Diagnostics Gmbh | Uso de eritropoyetina en bajas dosis para producir un preparado farmaceutico para el tratamiento de hemocromatosis, preparado farmaceutico combinadoutilizado segun dicho uso y envase farmaceutico unitario que contiene al referido preparado farmaceutico combinado |
| US6284234B1 (en) * | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| AU784550B2 (en) * | 1999-04-13 | 2006-05-04 | Kenneth S. Warren Institute, Inc., The | Modulation of excitable tissue function by peripherally administered erythropoietin |
| US7078376B1 (en) * | 2000-08-11 | 2006-07-18 | Baxter Healthcare S.A. | Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects |
| DE60232870D1 (de) * | 2001-04-04 | 2009-08-20 | Genodyssee | Neue polynukleotide und polypeptide des erythropoietingens |
| US20030068297A1 (en) * | 2001-08-18 | 2003-04-10 | Deepak Jain | Composition and methods for skin rejuvenation and repair |
| US6784154B2 (en) * | 2001-11-01 | 2004-08-31 | University Of Utah Research Foundation | Method of use of erythropoietin to treat ischemic acute renal failure |
| EP1471930B1 (en) * | 2002-01-09 | 2007-04-11 | Crucell Holland B.V. | Use of erythropoietin for the preventive or curative treatment of cardiac failure |
| WO2003103608A2 (en) * | 2002-06-11 | 2003-12-18 | The Burnham Institute | Neuroprotective synergy of erythropoietin and insulin-like growth factor |
| US20040009908A1 (en) * | 2002-07-10 | 2004-01-15 | Stamler Jonathan S. | Methods for treating or preventing ischemic injury |
| DE10234192B4 (de) * | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| WO2005037304A1 (en) * | 2003-10-17 | 2005-04-28 | Crucell Holland B.V. | Treatment and prevention of decubitus |
| JP4947883B2 (ja) | 2004-07-30 | 2012-06-06 | キヤノン株式会社 | 通信装置、制御方法ならびにプログラム |
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2004
- 2004-01-23 DE DE102004063927A patent/DE102004063927A1/de not_active Ceased
- 2004-01-23 DE DE102004004509A patent/DE102004004509B4/de not_active Expired - Fee Related
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2005
- 2005-01-22 CN CNA2009101341892A patent/CN101601857A/zh active Pending
- 2005-01-22 WO PCT/EP2005/000618 patent/WO2005070450A2/de not_active Ceased
- 2005-01-22 EA EA200900874A patent/EA200900874A1/ru unknown
- 2005-01-22 EP EP09014673A patent/EP2156843A3/de not_active Withdrawn
- 2005-01-22 EA EA200702523A patent/EA200702523A1/ru unknown
- 2005-01-22 AU AU2005205917A patent/AU2005205917B2/en not_active Ceased
- 2005-01-22 US US10/586,896 patent/US20070161552A1/en not_active Abandoned
- 2005-01-22 CN CNA2005800094258A patent/CN1942200A/zh active Pending
- 2005-01-22 EA EA200601359A patent/EA015350B1/ru not_active IP Right Cessation
- 2005-01-22 NZ NZ548697A patent/NZ548697A/en unknown
- 2005-01-22 SG SG200900491-2A patent/SG149875A1/en unknown
- 2005-01-22 KR KR1020067016711A patent/KR20070007082A/ko not_active Ceased
- 2005-01-22 CA CA002554234A patent/CA2554234A1/en not_active Abandoned
- 2005-01-22 BR BRPI0507048-1A patent/BRPI0507048A/pt not_active IP Right Cessation
- 2005-01-22 EP EP05715203A patent/EP1711201A2/de not_active Withdrawn
- 2005-01-22 JP JP2006550060A patent/JP2007518769A/ja active Pending
- 2005-01-22 UA UAA200609280A patent/UA86400C2/ru unknown
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2006
- 2006-07-23 IL IL177017A patent/IL177017A0/en unknown
- 2006-08-04 ZA ZA2006/06515A patent/ZA200606515B/en unknown
- 2006-08-18 NO NO20063716A patent/NO20063716L/no not_active Application Discontinuation
-
2010
- 2010-02-19 AU AU2010200621A patent/AU2010200621A1/en not_active Abandoned
- 2010-05-17 JP JP2010113592A patent/JP2010235613A/ja not_active Withdrawn
- 2010-10-05 IL IL208497A patent/IL208497A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG149875A1 (en) | 2009-02-27 |
| EA200601359A1 (ru) | 2006-12-29 |
| DE102004004509B4 (de) | 2010-07-01 |
| EP2156843A3 (de) | 2011-12-28 |
| JP2010235613A (ja) | 2010-10-21 |
| AU2005205917B2 (en) | 2010-11-18 |
| WO2005070450A2 (de) | 2005-08-04 |
| AU2005205917A1 (en) | 2005-08-04 |
| EA015350B1 (ru) | 2011-06-30 |
| EA200900874A1 (ru) | 2009-10-30 |
| ZA200606515B (en) | 2008-01-08 |
| WO2005070450A8 (de) | 2005-10-13 |
| BRPI0507048A (pt) | 2007-06-12 |
| EP2156843A2 (de) | 2010-02-24 |
| DE102004004509A1 (de) | 2005-08-18 |
| WO2005070450A3 (de) | 2005-12-08 |
| IL177017A0 (en) | 2006-12-10 |
| US20070161552A1 (en) | 2007-07-12 |
| KR20070007082A (ko) | 2007-01-12 |
| DE102004063927A1 (de) | 2005-12-15 |
| EP1711201A2 (de) | 2006-10-18 |
| EA200702523A1 (ru) | 2008-04-28 |
| AU2010200621A1 (en) | 2010-03-11 |
| UA86400C2 (ru) | 2009-04-27 |
| CN101601857A (zh) | 2009-12-16 |
| CN1942200A (zh) | 2007-04-04 |
| CA2554234A1 (en) | 2005-08-04 |
| NZ548697A (en) | 2011-01-28 |
| JP2007518769A (ja) | 2007-07-12 |
| IL208497A0 (en) | 2010-12-30 |
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