NO20071095L - Hittil ukjente tiofenderivater - Google Patents

Hittil ukjente tiofenderivater

Info

Publication number
NO20071095L
NO20071095L NO20071095A NO20071095A NO20071095L NO 20071095 L NO20071095 L NO 20071095L NO 20071095 A NO20071095 A NO 20071095A NO 20071095 A NO20071095 A NO 20071095A NO 20071095 L NO20071095 L NO 20071095L
Authority
NO
Norway
Prior art keywords
thiophene derivatives
hitherto unknown
derivatives
hitherto
unknown
Prior art date
Application number
NO20071095A
Other languages
English (en)
Norwegian (no)
Inventor
Martin Bolli
Thomas Weller
Walter Fischli
Martine Clozel
Oliver Nayler
Daniel Bur
Claus Mueller
Michael Scherz
David Lehmann
Boris Mathys
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of NO20071095L publication Critical patent/NO20071095L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20071095A 2004-07-29 2007-02-27 Hittil ukjente tiofenderivater NO20071095L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2004/008501 WO2006010379A1 (en) 2004-07-29 2004-07-29 Novel thiophene derivatives as immunosuppressive agents
PCT/EP2005/007892 WO2006010544A2 (en) 2004-07-29 2005-07-20 1, 1a, 5, 5a-tetrahydro-3-thia-cyclopropa’a! pentalenes: tricyclic thiophene derivatives as s1p1/edg1 receptor agonists

Publications (1)

Publication Number Publication Date
NO20071095L true NO20071095L (no) 2007-02-27

Family

ID=34958296

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071095A NO20071095L (no) 2004-07-29 2007-02-27 Hittil ukjente tiofenderivater

Country Status (23)

Country Link
US (1) US7750040B2 (de)
EP (1) EP1805163B1 (de)
JP (1) JP4807884B2 (de)
KR (1) KR20070046849A (de)
CN (1) CN1993346B (de)
AR (1) AR050273A1 (de)
AT (1) ATE409697T1 (de)
AU (1) AU2005266529A1 (de)
BR (1) BRPI0513841A (de)
CA (1) CA2574305A1 (de)
DE (1) DE602005010109D1 (de)
DK (1) DK1805163T3 (de)
ES (1) ES2313391T3 (de)
IL (1) IL180962A0 (de)
MX (1) MX2007000972A (de)
NO (1) NO20071095L (de)
PL (1) PL1805163T3 (de)
PT (1) PT1805163E (de)
RU (1) RU2386626C2 (de)
SI (1) SI1805163T1 (de)
TW (1) TW200616994A (de)
WO (2) WO2006010379A1 (de)
ZA (1) ZA200700535B (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4678139B2 (ja) * 2004-05-10 2011-04-27 トヨタ自動車株式会社 自動車の暖房制御システム
WO2006010379A1 (en) 2004-07-29 2006-02-02 Actelion Pharmaceuticals Ltd. Novel thiophene derivatives as immunosuppressive agents
EP1781595A1 (de) 2004-08-13 2007-05-09 Praecis Pharmaceuticals Inc. Verfahren und zusammensetzungen zur modulation von sphingosin-1-phosphat-rezeptoraktivität
RU2404178C2 (ru) * 2005-03-23 2010-11-20 Актелион Фармасьютиклз Лтд Новые производные тиофена в качестве агонистов рецептора сфингозин-1-фосфата-1
BRPI0609665A2 (pt) * 2005-03-23 2010-04-20 Actelion Pharmaceuticals Ltd composto, composição farmacêutica, e, uso de um composto
JP5047941B2 (ja) * 2005-03-23 2012-10-10 アクテリオン ファーマシューティカルズ リミテッド 免疫調節物質としての水素付加されたベンゾ(c)チオフェン誘導体
KR20080024533A (ko) * 2005-06-24 2008-03-18 액테리온 파마슈티칼 리미티드 신규한 티오펜 유도체
AR057894A1 (es) * 2005-11-23 2007-12-26 Actelion Pharmaceuticals Ltd Derivados de tiofeno
TWI404706B (zh) * 2006-01-11 2013-08-11 Actelion Pharmaceuticals Ltd 新穎噻吩衍生物
DE602007003074D1 (de) 2006-01-24 2009-12-17 Actelion Pharmaceuticals Ltd Neue pyrinderivate
TWI408139B (zh) * 2006-09-07 2013-09-11 Actelion Pharmaceuticals Ltd 新穎噻吩衍生物
MY149853A (en) * 2006-09-07 2013-10-31 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives as immunomodulating agents
EP2069335B1 (de) * 2006-09-08 2012-12-26 Actelion Pharmaceuticals Ltd. Pyridin-3-yl-derivate als immunmodulatoren
DE102007019679B4 (de) 2006-11-06 2025-04-30 Carl Zeiss Meditec Ag Operationsmikroskop mit OCT-System
DE102007019677A1 (de) 2006-11-06 2008-05-08 Carl Zeiss Surgical Gmbh Operationsmikroskop mit OCT-System und Operationsmikroskop-Beleuchtungsmodul mit OCT-System
DE102007019680A1 (de) 2006-11-06 2008-05-08 Carl Zeiss Surgical Gmbh Ophthalmo-Operationsmikroskop mit OCT-System
CN101627034B (zh) * 2007-03-16 2013-05-15 埃科特莱茵药品有限公司 氨基-吡啶衍生物作为s1p1/edg1受体激动剂
WO2009011850A2 (en) * 2007-07-16 2009-01-22 Abbott Laboratories Novel therapeutic compounds
CN101896482B (zh) * 2007-12-10 2013-01-09 埃科特莱茵药品有限公司 作为s1p1/edg1激动剂的噻吩衍生物
WO2009074969A2 (en) * 2007-12-12 2009-06-18 University Of Lausanne Sphingosine-1-phosphate, analogs and antagonists for use as medicaments
ES2389042T3 (es) * 2008-03-06 2012-10-22 Actelion Pharmaceuticals Ltd. Compuestos de piridina
BRPI0909055A2 (pt) * 2008-03-07 2019-02-26 Actelion Pharmaceuticals Ltd composto derivado de piridin-2-il, composição farmacêutica que o contém e uso desse composto.
HRP20170246T4 (hr) 2008-03-17 2020-02-07 Actelion Pharmaceuticals Ltd. Režim doziranja za selektivni agonist s1p1-receptora
US8735387B2 (en) 2008-07-15 2014-05-27 Sanofi Oxazolopyrimidines as Edg-1 receptor agonists
KR101728374B1 (ko) 2008-07-23 2017-04-19 아레나 파마슈티칼스, 인크. 자가면역성 및 염증성의 장애의 치료에 유용한 치환된 1,2,3,4-테트라히드로시클로펜타[b]인돌-3-일)아세트산 유도체
PL2342205T3 (pl) 2008-08-27 2016-12-30 Podstawione tricykliczne pochodne kwasowe jako antagoniści receptora S1P1 użyteczni w leczeniu zaburzeń autoimmunologicznych i zapalnych
DE102009002514A1 (de) 2009-04-21 2010-10-28 Evonik Degussa Gmbh Verfahren zur Herstellung von substituierten 1,4-Chinonmethiden
MX2012000414A (es) 2009-07-16 2012-02-08 Actelion Pharmaceuticals Ltd Derivados piridin-4-ilo.
SG178907A1 (en) * 2009-08-28 2012-04-27 Arena Pharm Inc Cannabinoid receptor modulators
CN103221391B (zh) 2010-01-27 2018-07-06 艾尼纳制药公司 (R)-2-(7-(4-环戊基-3-(三氟甲基)苄基氧基)-1,2,3,4-四氢环戊二烯并[b]吲哚-3-基)乙酸及其盐的制备方法
ES2558087T3 (es) 2010-03-03 2016-02-01 Arena Pharmaceuticals, Inc. Procesos para la preparación de moduladores del receptor S1P1 y formas cristalinas de los mismos
MY163185A (en) 2011-01-19 2017-08-15 Idorsia Pharmaceuticals Ltd 2-methoxy-pyridin-4-yl derivatives
US9597340B2 (en) 2011-02-25 2017-03-21 Arena Pharmaceuticals, Inc. Cannabinoid receptor modulators
LT2885266T (lt) 2012-08-17 2020-07-10 Actelion Pharmaceuticals Ltd (2z,5z)-5-(3-chlor-4-((r)-2,3-dihidroksipropoksi)benziliden)-2-(propilimino)-3-(o-tolil)tiazolidin-4-ono gamybos būdas ir šiame procese naudojamas tarpinis junginys
DE102013208091B4 (de) 2013-05-02 2019-05-09 Carl Zeiss Ag Vorrichtung und Verfahren zum Vermessen einer Flächentopografie
DE102014222629A1 (de) 2014-11-05 2016-05-12 Carl Zeiss Meditec Ag Untersuchen eines Objekts mit OCT-Abtastlichtstrahlen
DE202014011051U1 (de) 2014-11-05 2017-07-26 Carl Zeiss Meditec Ag Vorrichtung für das Untersuchen eines Patientenauges
DE202014011050U1 (de) 2014-11-05 2017-07-26 Carl Zeiss Meditec Ag Vorrichtung für das Untersuchen eines Patientenauges
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
ES2770348T3 (es) 2015-05-20 2020-07-01 Idorsia Pharmaceuticals Ltd Forma cristalina del compuesto (s)-3-{4-[5-(2-ciclopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi}-propano-1,2-diol
US10111841B2 (en) 2015-06-19 2018-10-30 University Of South Florida Stabilization of alcohol intoxication-induced cardiovascular instability
WO2016209809A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders
AU2018222747A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
US11534424B2 (en) 2017-02-16 2022-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
KR20200005614A (ko) 2017-05-08 2020-01-15 아레나 파마슈티칼스, 인크. 내장 통증의 치료를 위한 화합물 및 방법
US11492318B2 (en) * 2017-05-19 2022-11-08 Etna-Tec, Ltd. Methods for making functionalized fluorinated monomers, fluorinated monomers, and compositions for making the same
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1
US11555015B2 (en) 2018-09-06 2023-01-17 Arena Pharmaceuticals, Inc. Compounds useful in the treatment of autoimmune and inflammatory disorders
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
CN113072519A (zh) * 2021-04-01 2021-07-06 福建海西新药创制有限公司 一种利用微反应装置连续生产非布司他的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2599740B1 (fr) 1986-06-05 1988-08-12 Rhone Poulenc Sante Derives de benzo(b)thiophene de benzo(b)furannecarboxamides, leurs procedes de preparation et les medicaments les contenant
US4963557A (en) 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
AU7686891A (en) 1990-04-05 1991-10-30 American National Red Cross, The A protein family related to immediate-early protein expressed by human endothelial cells during differentiation
AU653957B2 (en) 1990-09-20 1994-10-20 Merrell Dow Pharmaceuticals Inc. 1-aryl-3-pyridinyl-2-propene-1-ones
US6423508B1 (en) 1998-03-09 2002-07-23 Smithkline Beecham Corporation Polynucleotide sequences of human EDG-1c
GB9808665D0 (en) * 1998-04-23 1998-06-24 Merck Sharp & Dohme Therapeutic compounds
WO2003014107A1 (en) 2001-08-01 2003-02-20 Basell Polyolefine Gmbh Process for the preparation of heterocyclic pentalene derivatives
US20040058894A1 (en) * 2002-01-18 2004-03-25 Doherty George A. Selective S1P1/Edg1 receptor agonists
AU2003202994B2 (en) 2002-01-18 2007-11-22 Merck Sharp & Dohme Corp. N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists
JP2005533058A (ja) 2002-06-17 2005-11-04 メルク エンド カムパニー インコーポレーテッド Edg受容体アゴニストとしての1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)アゼチジン−3−カルボキシラートおよび1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)ピロリジン−3−カルボキシラート
DE10231370B4 (de) 2002-07-11 2006-04-06 Sanofi-Aventis Deutschland Gmbh Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
EP1546110A4 (de) 2002-07-30 2008-03-26 Univ Virginia Verbindungen mit wirkung bei der signalübertragung mittels sphingosin-1-phosphat
WO2004035538A1 (en) 2002-10-15 2004-04-29 Merck & Co., Inc. Process for making azetidine-3-carboxylic acid
CN1788008A (zh) 2003-05-15 2006-06-14 麦克公司 作为s1p受体激动剂的3-(2-氨基-1-氮杂环基)-5-芳基-1,2,4-噁二唑
TW200505416A (en) 2003-08-12 2005-02-16 Mitsubishi Pharma Corp Bi-aryl compound having immunosuppressive activity
AU2004277947A1 (en) 2003-10-01 2005-04-14 Merck & Co., Inc. 3,5-aryl, heteroaryl or cycloalkyl substituted-1,2,4-oxadiazoles as S1P receptor agonists
AU2004299456B2 (en) 2003-12-17 2010-10-07 Merck Sharp & Dohme Corp. (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists
WO2006010379A1 (en) 2004-07-29 2006-02-02 Actelion Pharmaceuticals Ltd. Novel thiophene derivatives as immunosuppressive agents
JP5047941B2 (ja) 2005-03-23 2012-10-10 アクテリオン ファーマシューティカルズ リミテッド 免疫調節物質としての水素付加されたベンゾ(c)チオフェン誘導体
RU2404178C2 (ru) 2005-03-23 2010-11-20 Актелион Фармасьютиклз Лтд Новые производные тиофена в качестве агонистов рецептора сфингозин-1-фосфата-1
BRPI0609665A2 (pt) * 2005-03-23 2010-04-20 Actelion Pharmaceuticals Ltd composto, composição farmacêutica, e, uso de um composto
WO2006131336A1 (en) 2005-06-08 2006-12-14 Novartis Ag POLYCYCLIC OXADIAZOLES OR I SOXAZOLES AND THEIR USE AS SlP RECEPTOR LIGANDS
KR20080024533A (ko) 2005-06-24 2008-03-18 액테리온 파마슈티칼 리미티드 신규한 티오펜 유도체
AR057894A1 (es) 2005-11-23 2007-12-26 Actelion Pharmaceuticals Ltd Derivados de tiofeno
GB0601744D0 (en) 2006-01-27 2006-03-08 Novartis Ag Organic compounds
US20080005421A1 (en) 2006-05-19 2008-01-03 Chi-Tung Chang Switching Device of Input and Output Interfaces of Computer Systems
EP2109364A4 (de) 2006-12-15 2010-04-14 Abbott Lab Neuartige oxadiazolverbindungen
WO2008091967A1 (en) 2007-01-26 2008-07-31 Smithkline Beecham Corporation Chemical compounds

Also Published As

Publication number Publication date
PT1805163E (pt) 2008-12-05
RU2007107164A (ru) 2008-09-10
BRPI0513841A (pt) 2008-05-20
WO2006010544A2 (en) 2006-02-02
JP2008508210A (ja) 2008-03-21
CN1993346B (zh) 2011-04-27
AR050273A1 (es) 2006-10-11
IL180962A0 (en) 2007-07-04
WO2006010544A3 (en) 2006-03-30
EP1805163A2 (de) 2007-07-11
ES2313391T3 (es) 2009-03-01
ZA200700535B (en) 2008-10-29
US7750040B2 (en) 2010-07-06
AU2005266529A1 (en) 2006-02-02
RU2386626C2 (ru) 2010-04-20
DE602005010109D1 (de) 2008-11-13
JP4807884B2 (ja) 2011-11-02
TW200616994A (en) 2006-06-01
EP1805163B1 (de) 2008-10-01
WO2006010379A1 (en) 2006-02-02
KR20070046849A (ko) 2007-05-03
ATE409697T1 (de) 2008-10-15
CN1993346A (zh) 2007-07-04
PL1805163T3 (pl) 2009-04-30
CA2574305A1 (en) 2006-02-02
US20080064740A1 (en) 2008-03-13
MX2007000972A (es) 2007-04-10
SI1805163T1 (sl) 2009-02-28
DK1805163T3 (da) 2008-12-15

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