NO20073723L - Ibandronatpolymorf A - Google Patents

Ibandronatpolymorf A

Info

Publication number
NO20073723L
NO20073723L NO20073723A NO20073723A NO20073723L NO 20073723 L NO20073723 L NO 20073723L NO 20073723 A NO20073723 A NO 20073723A NO 20073723 A NO20073723 A NO 20073723A NO 20073723 L NO20073723 L NO 20073723L
Authority
NO
Norway
Prior art keywords
ibandronate
ibandronate polymorph
polymorph
hydroxypropane
pentyl
Prior art date
Application number
NO20073723A
Other languages
English (en)
Inventor
Uwe Eiermann
Bernd Junghans
Bernhard Knipp
Tim Sattelkau
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36090730&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20073723(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20073723L publication Critical patent/NO20073723L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår en ny polymorf krystallform av 3-(N-metyl-N-pentyl) amino-1-hydroksypropan-1,1-difosfonsyre mononatriumsalt monohydrat (Ibandronat) med den følgende formel Formel 1
NO20073723A 2005-02-01 2007-07-18 Ibandronatpolymorf A NO20073723L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05100686 2005-02-01
PCT/EP2006/000580 WO2006081963A1 (en) 2005-02-01 2006-01-24 Ibandronate polymorph a

Publications (1)

Publication Number Publication Date
NO20073723L true NO20073723L (no) 2007-08-28

Family

ID=36090730

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073723A NO20073723L (no) 2005-02-01 2007-07-18 Ibandronatpolymorf A

Country Status (25)

Country Link
US (1) US7714158B2 (no)
EP (2) EP1848728B1 (no)
JP (2) JP5828608B2 (no)
KR (1) KR100908529B1 (no)
CN (1) CN101111504B (no)
AR (1) AR053012A1 (no)
AU (1) AU2006210009B2 (no)
BR (1) BRPI0607092A2 (no)
CA (1) CA2594802C (no)
CY (1) CY1121703T1 (no)
DK (1) DK2662380T3 (no)
ES (2) ES2712644T3 (no)
HU (1) HUE042316T2 (no)
IL (1) IL184562A (no)
LT (1) LT2662380T (no)
MX (1) MX2007009107A (no)
NO (1) NO20073723L (no)
PL (1) PL2662380T3 (no)
PT (1) PT2662380T (no)
RU (1) RU2368617C2 (no)
SI (1) SI2662380T1 (no)
TR (1) TR201902609T4 (no)
TW (1) TWI374889B (no)
WO (1) WO2006081963A1 (no)
ZA (1) ZA200706168B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005025977D1 (de) 2004-08-23 2011-03-03 Teva Pharma Kristalline form des ibandronat-natriums und herstellungsverfahren dafür
JP5828607B2 (ja) * 2005-02-01 2015-12-09 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ イバンドロネート多形ｂ
WO2007074475A2 (en) * 2005-12-27 2007-07-05 Natco Pharma Limited Novel polymorphic forms of ibandronate
CA2656053A1 (en) * 2006-07-03 2008-01-10 Generics [Uk] Limited Novel process for the preparation of bisphosphonic acids
US20090012047A1 (en) * 2006-11-16 2009-01-08 Eran Turgeman Crystalline forms of ibandronate sodium
CA2570949A1 (en) * 2006-12-12 2008-06-12 Apotex Pharmachem Inc. Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
CN101679465B (zh) * 2007-04-11 2013-08-21 霍夫曼-拉罗奇有限公司 伊班膦酸盐的制备方法
KR20100014728A (ko) 2007-04-19 2010-02-10 닥터 레디스 레보러터리즈 리미티드 이반드로네이트 나트륨 다형태
US20090042839A1 (en) * 2007-08-09 2009-02-12 Sharon Avhar-Maydan Crystalline forms of ibandronate sodium
EP2128166A1 (en) 2008-05-20 2009-12-02 Chemo Ibérica, S.A. Polymorphic forms of Ibandronate sodium and processes for preparation thereof
EP2180003A1 (en) 2008-10-21 2010-04-28 Zentiva, k.s. Preparation of ibandronate trisodium
WO2012007021A1 (en) 2010-07-14 2012-01-19 Pharmathen S.A. Process for the preparation of 3-(n-methyl-n-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid salt or derivatives thereof
TR201200588A2 (tr) 2012-01-18 2012-07-23 Koçak Farma İlaç Ve Ki̇mya Sanayi̇ Anoni̇m Şi̇rketi̇ Sodyum ibandronat monohidrat polimorflarini ve polimorflu karışımlarını hazırlamak için prosesler.
KR20200085441A (ko) 2019-01-07 2020-07-15 엠에프씨 주식회사 이반드로네이트의 신규한 결정형 및 이의 제조방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
TW198039B (no) * 1988-11-28 1993-01-11 Ciba Geigy Ag
RU2172742C2 (ru) * 1995-12-28 2001-08-27 Пфайзер Инк. Стимуляторы секреции гормона роста
IT1303672B1 (it) * 1998-07-28 2001-02-23 Nicox Sa Sali nitrati di farmaci attivi nei disordini ossei
EP0998932A1 (de) 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
SK284569B6 (sk) 1998-10-16 2005-06-02 Akzo Nobel N.V. Vysoko čistá zlúčenina (7alfa, 17alfa)-17-hydroxy-7-metyl-19-nor- 17-pregn-5(10)-én-20-ín-3-ón, spôsob jej prípravy a farmaceutická dávková jednotka s jej obsahom
AU756540B2 (en) 1998-12-04 2003-01-16 Roche Diagnostics Gmbh Use of ibandronate for promoting osseointegration of endoprostheses
US6677320B2 (en) * 2000-01-20 2004-01-13 Hoffmann-La Roches Inc. Parenteral bisphosphonate composition with improved local tolerance
CN1404836A (zh) * 2001-09-14 2003-03-26 中生北方生物工程开发研究所 埃本膦酸钠作为预防和治疗骨质疏松症的药物的有效成分的应用
KR20140021045A (ko) 2002-05-10 2014-02-19 에프. 호프만-라 로슈 아게 골다공증 치료 및 예방용 비스포스폰산
NZ536273A (en) 2002-12-20 2007-08-31 Hoffmann La Roche High dose ibandronate formulation
WO2006002348A2 (en) * 2004-06-23 2006-01-05 Teva Pharmaceutical Industies Ltd. Solid and crystalline ibandronic acid
DE602005025977D1 (de) * 2004-08-23 2011-03-03 Teva Pharma Kristalline form des ibandronat-natriums und herstellungsverfahren dafür

Also Published As

Publication number Publication date
AU2006210009A1 (en) 2006-08-10
IL184562A0 (en) 2007-10-31
JP2008529980A (ja) 2008-08-07
RU2007132701A (ru) 2009-03-10
EP1848728A1 (en) 2007-10-31
PT2662380T (pt) 2019-02-27
ES2478302T3 (es) 2014-07-21
MX2007009107A (es) 2007-09-11
US7714158B2 (en) 2010-05-11
ZA200706168B (en) 2008-09-25
CN101111504A (zh) 2008-01-23
US20060172975A1 (en) 2006-08-03
EP2662380B1 (en) 2018-11-21
CA2594802A1 (en) 2006-08-10
CY1121703T1 (el) 2020-07-31
TWI374889B (en) 2012-10-21
KR20070100394A (ko) 2007-10-10
AR053012A1 (es) 2007-04-18
ES2712644T3 (es) 2019-05-14
TW200638939A (en) 2006-11-16
SI2662380T1 (sl) 2019-04-30
TR201902609T4 (tr) 2019-03-21
CN101111504B (zh) 2011-12-21
BRPI0607092A2 (pt) 2009-08-04
EP1848728B1 (en) 2014-06-11
EP2662380A1 (en) 2013-11-13
IL184562A (en) 2015-11-30
JP2015205907A (ja) 2015-11-19
PL2662380T3 (pl) 2019-05-31
WO2006081963A1 (en) 2006-08-10
RU2368617C2 (ru) 2009-09-27
JP6039754B2 (ja) 2016-12-07
CA2594802C (en) 2012-11-27
AU2006210009B2 (en) 2009-08-13
HUE042316T2 (hu) 2019-06-28
DK2662380T3 (en) 2019-03-18
KR100908529B1 (ko) 2009-07-20
JP5828608B2 (ja) 2015-12-09
LT2662380T (lt) 2019-03-12

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: ATNAHS PHARMA UK LIMITED, GB

FC2A Withdrawal, rejection or dismissal of laid open patent application