NO20075567L - 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet - Google Patents

4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet

Info

Publication number
NO20075567L
NO20075567L NO20075567A NO20075567A NO20075567L NO 20075567 L NO20075567 L NO 20075567L NO 20075567 A NO20075567 A NO 20075567A NO 20075567 A NO20075567 A NO 20075567A NO 20075567 L NO20075567 L NO 20075567L
Authority
NO
Norway
Prior art keywords
oxo
phenyl
infertility
drugs
treatment
Prior art date
Application number
NO20075567A
Other languages
English (en)
Norwegian (no)
Inventor
Cornelis Marius Timmers
Willem Frederik Johan Karstens
Pedro Manuel Grima Poveda
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of NO20075567L publication Critical patent/NO20075567L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20075567A 2005-05-04 2007-11-05 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet NO20075567L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05103738 2005-05-04
PCT/EP2006/061976 WO2006117370A1 (en) 2005-05-04 2006-05-02 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY

Publications (1)

Publication Number Publication Date
NO20075567L true NO20075567L (no) 2007-12-03

Family

ID=34939695

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075567A NO20075567L (no) 2005-05-04 2007-11-05 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet

Country Status (28)

Country Link
US (1) US8034945B2 (sr)
EP (1) EP1879580B1 (sr)
JP (1) JP5129738B2 (sr)
KR (1) KR20080010427A (sr)
CN (1) CN101212972B (sr)
AR (1) AR056338A1 (sr)
AT (1) ATE424823T1 (sr)
AU (1) AU2006243190B2 (sr)
BR (1) BRPI0611118A2 (sr)
CA (1) CA2606682C (sr)
CY (1) CY1109076T1 (sr)
DE (1) DE602006005640D1 (sr)
DK (1) DK1879580T3 (sr)
ES (1) ES2322295T3 (sr)
HR (1) HRP20090189T1 (sr)
IL (1) IL186676A (sr)
MX (1) MX2007013742A (sr)
NO (1) NO20075567L (sr)
NZ (1) NZ562685A (sr)
PE (1) PE20061440A1 (sr)
PL (1) PL1879580T3 (sr)
PT (1) PT1879580E (sr)
RS (1) RS50968B (sr)
RU (1) RU2403243C2 (sr)
SI (1) SI1879580T1 (sr)
UA (1) UA92008C2 (sr)
WO (1) WO2006117370A1 (sr)
ZA (1) ZA200709094B (sr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1879866T3 (da) * 2005-05-04 2011-06-06 Organon Nv Dihydropyridinderivater
UA92007C2 (ru) * 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности
UA92009C2 (ru) * 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия
TW200944523A (en) 2008-02-08 2009-11-01 Organon Nv (Dihydro)pyrrolo[2,1-a]isoquinolines
US8071587B2 (en) 2009-05-27 2011-12-06 N. V. Organon (Dihydro)imidazoiso[5,1-A]quinolines
TW201116531A (en) 2009-07-29 2011-05-16 Organon Nv Ring-annulated dihydropyrrolo[2,1-a]isoquinolines
US8431564B2 (en) 2009-07-29 2013-04-30 Merck Sharp & Dohme B.V. Ring-annulated dihydropyrrolo[2,1-α]isoquinolines
TW201116515A (en) 2009-07-31 2011-05-16 Organon Nv Dihydrobenzoindazoles
WO2011157654A1 (de) 2010-06-15 2011-12-22 Bayer Cropscience Ag Anthranilsäurediamid-derivate
RU2648352C1 (ru) * 2017-07-18 2018-03-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ лечения первичного бесплодия, обусловленного тромбофилиями при проведении экстракорпорального оплодотворения

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070162B (de) 1959-12-03 Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M Verfahren zur Herstellung von 5 - Brom - 3 - nitro - 4 - hydroxybenzaldehyd bzw. 5 - Chlor - 3 - nitro - 4 - hydroxybenzaldehyd
US5455253A (en) * 1992-10-20 1995-10-03 Zeneca Limited Heterocyclic derivatives
GB9318935D0 (en) * 1992-10-20 1993-10-27 Zeneca Ltd Heterocyclic derivatives
GB9407432D0 (en) * 1994-04-14 1994-06-08 Zeneca Ltd Heterocyclic derivative
DE4430639A1 (de) * 1994-08-29 1996-03-07 Bayer Ag Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten
GB9515445D0 (en) 1995-07-27 1995-09-27 Pharmacia Spa Dihydropyridine and pyridine derivatives and process for their preparation
AU7333496A (en) * 1995-10-19 1997-05-07 Takeda Chemical Industries Ltd. Quinoline derivatives as gnrh antagonists
US6593335B1 (en) 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
ATE279407T1 (de) 1998-08-07 2004-10-15 Applied Research Systems Fsh mimetika zur behandlung von infertilität
CA2425889A1 (en) 2000-07-27 2002-02-07 Smithkline Beecham Corporation Agonists of follicle stimulating hormone activity
RU2347570C2 (ru) 2001-07-02 2009-02-27 Н.В.Органон Тетрагидрохинолиновые производные
JP2003026630A (ja) 2001-07-13 2003-01-29 Taoka Chem Co Ltd カラーカプラー中間体用カルボン酸クロリド類の製造法
TWI322012B (en) 2002-12-20 2010-03-21 Organon Nv Tetrahydroquinoline derivatives
UA92007C2 (ru) 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности
DK1879866T3 (da) 2005-05-04 2011-06-06 Organon Nv Dihydropyridinderivater
UA92009C2 (ru) 2005-05-04 2010-09-27 Н.В. Органон Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия

Also Published As

Publication number Publication date
JP5129738B2 (ja) 2013-01-30
NZ562685A (en) 2010-10-29
EP1879580B1 (en) 2009-03-11
CN101212972B (zh) 2011-06-08
ES2322295T3 (es) 2009-06-18
US20080300270A1 (en) 2008-12-04
RU2403243C2 (ru) 2010-11-10
AR056338A1 (es) 2007-10-03
IL186676A (en) 2011-08-31
RS50968B (sr) 2010-10-31
AU2006243190A1 (en) 2006-11-09
PL1879580T3 (pl) 2009-08-31
AU2006243190B2 (en) 2011-04-07
KR20080010427A (ko) 2008-01-30
ATE424823T1 (de) 2009-03-15
CN101212972A (zh) 2008-07-02
CA2606682C (en) 2013-10-29
PT1879580E (pt) 2009-05-27
WO2006117370A1 (en) 2006-11-09
HRP20090189T1 (hr) 2009-05-31
US8034945B2 (en) 2011-10-11
SI1879580T1 (sl) 2009-06-30
ZA200709094B (en) 2008-09-25
RU2007144988A (ru) 2009-06-10
JP2008540378A (ja) 2008-11-20
EP1879580A1 (en) 2008-01-23
DK1879580T3 (da) 2009-05-18
DE602006005640D1 (de) 2009-04-23
MX2007013742A (es) 2008-01-24
IL186676A0 (en) 2008-02-09
BRPI0611118A2 (pt) 2010-11-09
PE20061440A1 (es) 2007-02-03
UA92008C2 (en) 2010-09-27
CY1109076T1 (el) 2014-07-02
CA2606682A1 (en) 2006-11-09

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