NO20075637L - 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet - Google Patents
4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitetInfo
- Publication number
- NO20075637L NO20075637L NO20075637A NO20075637A NO20075637L NO 20075637 L NO20075637 L NO 20075637L NO 20075637 A NO20075637 A NO 20075637A NO 20075637 A NO20075637 A NO 20075637A NO 20075637 L NO20075637 L NO 20075637L
- Authority
- NO
- Norway
- Prior art keywords
- oxo
- phenyl
- treatment
- infertility
- drugs
- Prior art date
Links
- GTFDKLAZHJQLIA-UHFFFAOYSA-N 4-phenyl-4,6,7,8-tetrahydro-1h-quinolin-5-one Chemical class O=C1CCCC(NC=C2)=C1C2C1=CC=CC=C1 GTFDKLAZHJQLIA-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 208000000509 infertility Diseases 0.000 title 1
- 230000036512 infertility Effects 0.000 title 1
- 231100000535 infertility Toxicity 0.000 title 1
- KHNADQLNEYSCBM-UHFFFAOYSA-N 2-methyl-4-phenyl-4,6,7,8-tetrahydro-1h-quinolin-5-one Chemical class C1CCC(=O)C2=C1NC(C)=CC2C1=CC=CC=C1 KHNADQLNEYSCBM-UHFFFAOYSA-N 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000021267 infertility disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05103741 | 2005-05-04 | ||
| PCT/EP2006/061978 WO2006117371A1 (en) | 2005-05-04 | 2006-05-02 | 4-PHENYL-5-0X0-l,4,5,6,7,8-HEXAHYDR0QËIN0LINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20075637L true NO20075637L (no) | 2008-01-29 |
Family
ID=34939698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20075637A NO20075637L (no) | 2005-05-04 | 2007-11-06 | 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8017782B2 (pl) |
| EP (1) | EP1879581B1 (pl) |
| JP (1) | JP5118631B2 (pl) |
| KR (1) | KR20080010445A (pl) |
| CN (1) | CN101212971B (pl) |
| AR (1) | AR054109A1 (pl) |
| AT (1) | ATE406895T1 (pl) |
| AU (1) | AU2006243194B2 (pl) |
| BR (1) | BRPI0611124A2 (pl) |
| CA (1) | CA2607106C (pl) |
| CY (1) | CY1108584T1 (pl) |
| DE (1) | DE602006002608D1 (pl) |
| DK (1) | DK1879581T3 (pl) |
| ES (1) | ES2313667T3 (pl) |
| HR (1) | HRP20080488T3 (pl) |
| IL (1) | IL186831A (pl) |
| MX (1) | MX2007013754A (pl) |
| MY (1) | MY144609A (pl) |
| NO (1) | NO20075637L (pl) |
| NZ (1) | NZ562804A (pl) |
| PE (1) | PE20061371A1 (pl) |
| PL (1) | PL1879581T3 (pl) |
| PT (1) | PT1879581E (pl) |
| RS (1) | RS50614B (pl) |
| RU (1) | RU2403249C2 (pl) |
| SI (1) | SI1879581T1 (pl) |
| TW (1) | TW200716553A (pl) |
| UA (1) | UA92009C2 (pl) |
| WO (1) | WO2006117371A1 (pl) |
| ZA (1) | ZA200709096B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| DK1879866T3 (da) * | 2005-05-04 | 2011-06-06 | Organon Nv | Dihydropyridinderivater |
| UA92007C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
| TW200944523A (en) | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| US8071587B2 (en) | 2009-05-27 | 2011-12-06 | N. V. Organon | (Dihydro)imidazoiso[5,1-A]quinolines |
| TW201116531A (en) | 2009-07-29 | 2011-05-16 | Organon Nv | Ring-annulated dihydropyrrolo[2,1-a]isoquinolines |
| US8431564B2 (en) | 2009-07-29 | 2013-04-30 | Merck Sharp & Dohme B.V. | Ring-annulated dihydropyrrolo[2,1-α]isoquinolines |
| TW201116515A (en) | 2009-07-31 | 2011-05-16 | Organon Nv | Dihydrobenzoindazoles |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1070162B (de) | 1959-12-03 | Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M | Verfahren zur Herstellung von 5 - Brom - 3 - nitro - 4 - hydroxybenzaldehyd bzw. 5 - Chlor - 3 - nitro - 4 - hydroxybenzaldehyd | |
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| GB9407432D0 (en) * | 1994-04-14 | 1994-06-08 | Zeneca Ltd | Heterocyclic derivative |
| DE4430639A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
| GB9515445D0 (en) | 1995-07-27 | 1995-09-27 | Pharmacia Spa | Dihydropyridine and pyridine derivatives and process for their preparation |
| AU7333496A (en) * | 1995-10-19 | 1997-05-07 | Takeda Chemical Industries Ltd. | Quinoline derivatives as gnrh antagonists |
| US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
| ATE279407T1 (de) | 1998-08-07 | 2004-10-15 | Applied Research Systems | Fsh mimetika zur behandlung von infertilität |
| CA2425889A1 (en) | 2000-07-27 | 2002-02-07 | Smithkline Beecham Corporation | Agonists of follicle stimulating hormone activity |
| RU2347570C2 (ru) | 2001-07-02 | 2009-02-27 | Н.В.Органон | Тетрагидрохинолиновые производные |
| JP2003026630A (ja) | 2001-07-13 | 2003-01-29 | Taoka Chem Co Ltd | カラーカプラー中間体用カルボン酸クロリド類の製造法 |
| TWI322012B (en) | 2002-12-20 | 2010-03-21 | Organon Nv | Tetrahydroquinoline derivatives |
| UA92007C2 (ru) | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
| DK1879866T3 (da) | 2005-05-04 | 2011-06-06 | Organon Nv | Dihydropyridinderivater |
| UA92008C2 (en) | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
-
2006
- 2006-02-05 UA UAA200711804A patent/UA92009C2/ru unknown
- 2006-05-02 BR BRPI0611124-6A patent/BRPI0611124A2/pt not_active IP Right Cessation
- 2006-05-02 AT AT06754954T patent/ATE406895T1/de active
- 2006-05-02 CN CN2006800235439A patent/CN101212971B/zh not_active Expired - Fee Related
- 2006-05-02 RU RU2007144984/04A patent/RU2403249C2/ru not_active IP Right Cessation
- 2006-05-02 DE DE602006002608T patent/DE602006002608D1/de not_active Expired - Lifetime
- 2006-05-02 US US11/912,756 patent/US8017782B2/en active Active
- 2006-05-02 PT PT06754954T patent/PT1879581E/pt unknown
- 2006-05-02 WO PCT/EP2006/061978 patent/WO2006117371A1/en not_active Ceased
- 2006-05-02 KR KR1020077027874A patent/KR20080010445A/ko not_active Ceased
- 2006-05-02 ES ES06754954T patent/ES2313667T3/es not_active Expired - Lifetime
- 2006-05-02 JP JP2008509437A patent/JP5118631B2/ja not_active Expired - Fee Related
- 2006-05-02 DK DK06754954T patent/DK1879581T3/da active
- 2006-05-02 NZ NZ562804A patent/NZ562804A/en not_active IP Right Cessation
- 2006-05-02 RS RSP-2008/0457A patent/RS50614B/sr unknown
- 2006-05-02 AU AU2006243194A patent/AU2006243194B2/en not_active Ceased
- 2006-05-02 PL PL06754954T patent/PL1879581T3/pl unknown
- 2006-05-02 HR HR20080488T patent/HRP20080488T3/xx unknown
- 2006-05-02 EP EP06754954A patent/EP1879581B1/en not_active Expired - Lifetime
- 2006-05-02 SI SI200630120T patent/SI1879581T1/sl unknown
- 2006-05-02 MX MX2007013754A patent/MX2007013754A/es active IP Right Grant
- 2006-05-02 CA CA2607106A patent/CA2607106C/en not_active Expired - Fee Related
- 2006-05-03 TW TW095115776A patent/TW200716553A/zh unknown
- 2006-05-03 MY MYPI20062028A patent/MY144609A/en unknown
- 2006-05-03 AR ARP060101781A patent/AR054109A1/es unknown
- 2006-05-03 PE PE2006000466A patent/PE20061371A1/es not_active Application Discontinuation
-
2007
- 2007-10-22 ZA ZA200709096A patent/ZA200709096B/xx unknown
- 2007-10-22 IL IL186831A patent/IL186831A/en not_active IP Right Cessation
- 2007-11-06 NO NO20075637A patent/NO20075637L/no not_active Application Discontinuation
-
2008
- 2008-11-20 CY CY20081101342T patent/CY1108584T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |