NO20076299L - Maling av bindingsraten til en bindende substans og en analytt - Google Patents

Maling av bindingsraten til en bindende substans og en analytt

Info

Publication number
NO20076299L
NO20076299L NO20076299A NO20076299A NO20076299L NO 20076299 L NO20076299 L NO 20076299L NO 20076299 A NO20076299 A NO 20076299A NO 20076299 A NO20076299 A NO 20076299A NO 20076299 L NO20076299 L NO 20076299L
Authority
NO
Norway
Prior art keywords
binding
analyte
rate
ultrasonics
substance
Prior art date
Application number
NO20076299A
Other languages
English (en)
Inventor
Kauko Kahma
Original Assignee
Orion Diagnostica Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Diagnostica Oy filed Critical Orion Diagnostica Oy
Publication of NO20076299L publication Critical patent/NO20076299L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

En metode til å måle bindingsraten til en bindende substans og en analytt, for eksempel i et assay, slik som et immunoassay, som anvender et initielt trinn bestående av å utføre ultrasonikering tilstrekkelig til å ødelegge/dissosiere bindingen mellom den bindende substansen og analytten. Etter opphør av ultrasonikeringen nedtegnes målinger for å bestemme bindingsraten ved opphør av nevnte ultrasonikering eller ved et forutbestemt tidspunkt etter dette. Ultrasonikeringen resulterer i kunnskap om det eksakte tidspunktet for start av bindingsreaksjonen, som sørger for en bedre måling av bindingshastigheten. ?? ?? ?? ??
NO20076299A 2005-05-09 2007-12-06 Maling av bindingsraten til en bindende substans og en analytt NO20076299L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0509419A GB2426050A (en) 2005-05-09 2005-05-09 Method of measuring binding rate using sonication
PCT/EP2006/004244 WO2006119933A1 (en) 2005-05-09 2006-05-05 Measurement of binding rate of a binding substance and an analyte

Publications (1)

Publication Number Publication Date
NO20076299L true NO20076299L (no) 2007-12-06

Family

ID=34685297

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076299A NO20076299L (no) 2005-05-09 2007-12-06 Maling av bindingsraten til en bindende substans og en analytt

Country Status (15)

Country Link
US (1) US8133693B2 (no)
EP (1) EP1880217B1 (no)
JP (1) JP4927824B2 (no)
CN (1) CN101171515B (no)
AT (1) ATE438855T1 (no)
AU (1) AU2006246008B2 (no)
CA (1) CA2606548C (no)
DE (1) DE602006008293D1 (no)
DK (1) DK1880217T3 (no)
ES (1) ES2328397T3 (no)
GB (1) GB2426050A (no)
NO (1) NO20076299L (no)
PL (1) PL1880217T3 (no)
PT (1) PT1880217E (no)
WO (1) WO2006119933A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263415B2 (en) * 2006-09-14 2012-09-11 Ge Healthcare Bio-Sciences Ab Method of determining analyte concentration
EP2015072A1 (en) * 2007-07-12 2009-01-14 LEK Pharmaceuticals D.D. Ultrasound elution of biological ligands

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4157871A (en) 1976-06-02 1979-06-12 Beckman Instruments, Inc. System for rate immunonephelometric analysis
US4268171A (en) 1977-07-18 1981-05-19 Beckman Instruments, Inc. Method determining concentration in rate nephelometric immunochemical analysis
US4204837A (en) 1978-03-14 1980-05-27 Beckman Instruments, Inc. Method of rate immunonephelometric analysis
US4205954A (en) 1978-05-26 1980-06-03 Warner-Lambert Company Kinetic latex agglutinometry
US4766083A (en) 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
US4575485A (en) 1983-08-29 1986-03-11 Syntex (U.S.A.) Inc. Ultrasonic enhanced immuno-reactions
US4615984A (en) 1984-02-23 1986-10-07 Becton Dickinson & Company Dissociation of ligand-binder complex using ultrasound
IL75648A0 (en) * 1984-07-05 1985-10-31 Gen Probe Inc Accelerated nucleic acid reassociation method
US4762413A (en) * 1984-09-07 1988-08-09 Olympus Optical Co., Ltd. Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light
US4835110A (en) 1985-12-23 1989-05-30 Beckman Instruments, Inc. Method for enhancing analysis timing in kinetic nephelometry
GB8905807D0 (en) 1989-03-14 1989-04-26 Health Lab Service Board Particle aggregation
CA2023803C (en) * 1989-08-23 1999-05-18 Takeshi Miyazaki Method for measuring an immunologically active material and apparatus suitable for practicing said method
GB2265004B (en) 1992-03-10 1996-01-10 Univ Cardiff Immuno-agglutination assay using ultrasonic standing wave field
US5371021A (en) 1992-07-17 1994-12-06 Beckman Instruments, Inc. Initial rate photometric method for immunoassay
AU4102896A (en) 1994-11-29 1996-06-19 Analogic Corporation Particle agglutination assay system
US5527710A (en) * 1994-12-02 1996-06-18 Igen, Inc. Rate measurements of biomolecular reactions using electrochemiluminescence
ATE317979T1 (de) * 1996-12-19 2006-03-15 Dade Behring Marburg Gmbh Immundissoziation zur verbesserung der immunchemischen bestimmung eines analyten
US6413783B1 (en) * 1997-09-18 2002-07-02 Meso Scale Technologies, Llc Assay sonication apparatus and methodology
US6086821A (en) 1999-03-29 2000-07-11 The United States Of America As Represented By The Secretary Of The Navy Ultrasonic force differentiation assay
DE10005301A1 (de) * 2000-02-07 2001-08-09 Trutnau Hans Heinrich Multi-Schritt-Kinetik molekularer Interaktionen als analytisches Mess- und Auswerte-Verfahren
US7348182B2 (en) * 2000-10-03 2008-03-25 Mirari Biosciences, Inc. Directed microwave chemistry
US20040265871A1 (en) * 2003-04-11 2004-12-30 Angelsen Bjorn A.J. Ultrasound stimulated DNA hybridization
US7373255B2 (en) * 2003-06-06 2008-05-13 Biacore Ab Method and system for determination of molecular interaction parameters
EP1678495A4 (en) * 2003-10-20 2007-06-27 Univ California TRANSDUCTION SYSTEMS IN THE NANOMASSIC STATION FOR DETECTING MOLECULAR INTERACTIONS
US7183119B2 (en) * 2004-11-15 2007-02-27 Eastman Kodak Company Method for sensitive detection of multiple biological analytes

Also Published As

Publication number Publication date
DE602006008293D1 (de) 2009-09-17
JP2008541070A (ja) 2008-11-20
EP1880217B1 (en) 2009-08-05
EP1880217A1 (en) 2008-01-23
JP4927824B2 (ja) 2012-05-09
CA2606548A1 (en) 2006-11-16
WO2006119933A1 (en) 2006-11-16
US20090215200A1 (en) 2009-08-27
US8133693B2 (en) 2012-03-13
AU2006246008A1 (en) 2006-11-16
ATE438855T1 (de) 2009-08-15
DK1880217T3 (da) 2009-12-07
GB2426050A (en) 2006-11-15
AU2006246008B2 (en) 2011-09-29
CN101171515B (zh) 2012-06-27
CN101171515A (zh) 2008-04-30
PT1880217E (pt) 2009-08-31
ES2328397T3 (es) 2009-11-12
CA2606548C (en) 2014-09-09
PL1880217T3 (pl) 2010-01-29
GB0509419D0 (en) 2005-06-15

Similar Documents

Publication Publication Date Title
WO2003043487A3 (en) Method of using a non-antibody protein to detect and measure an analyte
WO2008064034A8 (en) Cement bond analysis
MX2009000914A (es) Medios y metodos para evaluar el riesgo de intervenciones cardiacas basadas en el factor 15 de diferenciacion del crecimiento.
WO2004070352A3 (en) Methods, mixtures, kits and compositions pertaining to analyte determination
WO2007120699A3 (en) Reagents and methods for using human embryonic stem cells to evaluate toxicity of pharmaceutical compounds & other chemicals
NO20076662L (no) Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff
NO20091389L (no) Fremgangsmate for benyttelse av malinger av smerteterskel
WO2007062225A3 (en) Test substrate handling apparatus
EP1318399A3 (en) Passive sample detection to initiate timing of an assay
WO2003093494A3 (en) Apparatus including ion transport detecting structures and methods of use
ATE541054T1 (de) Bio-barcode erkennung für zielmoleküle
WO2006051088A3 (de) Vorrichtungen für die durchführung und analyse von mikroarray-experimenten
WO2007136980A3 (en) Diagnostic test media and methods for the manufacture thereof
WO2005003394A3 (en) Bio-barcode based detection of target analytes
ATE541216T1 (de) Fluoreszenztestverfahren
ATE370414T1 (de) Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs
WO2006031883A3 (en) Analysis of mhc-peptide binding interactions
NO20076299L (no) Maling av bindingsraten til en bindende substans og en analytt
WO2002099381A3 (en) A single-cell biosensor for the measurement of gpcr ligands in a test sample
WO2007030949A3 (en) Methods of diagnosing ovarian cancer and kits therefor
FI973561A7 (fi) Menetelmä ja yhdisteitä analysoitavien aineiden määrittämiseksi remane nssimittausten avulla ja mainittujen yhdisteiden käyttö
NO20062073L (no) Fremgangsmate og anordning for bestemmelse av petrokjemiske parametre
WO2006053251A3 (en) Method of measuring amyloid-beta peptides
DK1386160T3 (da) Fremgangsmåde til påvisning af blodcelle-antigener og antistoffer rettet mod disse
BRPI0415829A (pt) método para o teste ultra-sÈnico de um objeto, aparelho, e, uso do mesmo

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application