NO20076344L - Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptoren - Google Patents
Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptorenInfo
- Publication number
- NO20076344L NO20076344L NO20076344A NO20076344A NO20076344L NO 20076344 L NO20076344 L NO 20076344L NO 20076344 A NO20076344 A NO 20076344A NO 20076344 A NO20076344 A NO 20076344A NO 20076344 L NO20076344 L NO 20076344L
- Authority
- NO
- Norway
- Prior art keywords
- agonists
- piperazine
- ht1a receptor
- compounds
- ht1a
- Prior art date
Links
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 title abstract 3
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 title abstract 3
- LMRCKXYHPYNEJV-UHFFFAOYSA-N piperazine;piperidine Chemical compound C1CCNCC1.C1CNCCN1 LMRCKXYHPYNEJV-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000556 agonist Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 201000001880 Sexual dysfunction Diseases 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 231100000872 sexual dysfunction Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68946905P | 2005-06-10 | 2005-06-10 | |
| PCT/US2006/022719 WO2006135839A2 (en) | 2005-06-10 | 2006-06-09 | Piperazine-piperidine antagonists and agonists of the 5-ht1a receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076344L true NO20076344L (no) | 2008-02-27 |
Family
ID=37530084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076344A NO20076344L (no) | 2005-06-10 | 2007-12-11 | Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptoren |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7671056B2 (es) |
| EP (1) | EP1888559A2 (es) |
| JP (1) | JP2008543782A (es) |
| KR (1) | KR20080021134A (es) |
| CN (1) | CN101243073A (es) |
| AR (1) | AR055059A1 (es) |
| AU (1) | AU2006257874A1 (es) |
| BR (1) | BRPI0613491A2 (es) |
| CA (1) | CA2611711A1 (es) |
| CR (1) | CR9560A (es) |
| EC (1) | ECSP088094A (es) |
| GT (1) | GT200600255A (es) |
| IL (1) | IL187972A0 (es) |
| MX (1) | MX2007015678A (es) |
| NO (1) | NO20076344L (es) |
| PE (1) | PE20070069A1 (es) |
| RU (1) | RU2007146543A (es) |
| TW (1) | TW200800959A (es) |
| WO (1) | WO2006135839A2 (es) |
| ZA (1) | ZA200710699B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200800959A (en) | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
| TW200811144A (en) * | 2006-06-09 | 2008-03-01 | Wyeth Corp | Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline |
| TW200808741A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts |
| TW200808730A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Process for synthesizing piperazine-piperidine compounds |
| CN101466365A (zh) * | 2006-06-09 | 2009-06-24 | 惠氏公司 | 增强认知功能的方法 |
| TW200808740A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof |
| CL2007003410A1 (es) * | 2006-11-28 | 2008-04-11 | Wyeth Corp | Compuestos derivados de 5-fluoro-8-{4-[4-(6-metoxiquinolin-8-il)piperazin-1-il]piperidin-1-il}quinolina; procedimiento de preparacion; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento de trast |
| US20080199518A1 (en) * | 2006-11-28 | 2008-08-21 | Wyeth | Controlled-release formulation of piperazine-piperidine antagonists and agonists of the 5-HT1A receptor having enhanced intestinal dissolution |
| US20080226714A1 (en) * | 2007-02-16 | 2008-09-18 | Wyeth | Sustained-release tablet formulations of piperazine-piperidine antagonists and agonists of the 5-ht1a receptor having enhanced intestinal dissolution |
| WO2010033045A1 (en) * | 2008-09-16 | 2010-03-25 | Igor Anatolievich Pomytkin | Compositions and methods for prevention or treatment of beta amyloid deposition |
| WO2010081851A1 (en) | 2009-01-14 | 2010-07-22 | Genoscience Pharma | Piperidin-4-ylpiperazine compounds for the treatment of hcv infection |
| CN101797223B (zh) * | 2009-02-06 | 2012-05-23 | 上海交通大学医学院 | 石杉碱甲眼用制剂及其应用 |
| PT3061821T (pt) * | 2009-07-22 | 2019-09-05 | PureTech Health LLC | Composições para tratamento de distúrbios melhorados por ativação de recetores muscarínicos |
| US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
| KR102408292B1 (ko) | 2018-09-28 | 2022-06-10 | 카루나 세러퓨틱스 인코포레이티드 | 무스카린성 수용체 활성화에 의해 개선된 장애의 치료를 위한 조성물 및 방법 |
| KR20250129556A (ko) | 2024-02-22 | 2025-08-29 | 단국대학교 천안캠퍼스 산학협력단 | Fk960을 유효성분으로 포함하는 신경 질환 예방 또는 치료용 약학 조성물 |
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| JP4796927B2 (ja) | 2005-11-28 | 2011-10-19 | 株式会社豊田中央研究所 | クロック信号出力回路 |
| TW200808740A (en) | 2006-06-09 | 2008-02-16 | Wyeth Corp | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof |
| TW200808741A (en) | 2006-06-09 | 2008-02-16 | Wyeth Corp | 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts |
| CN101466365A (zh) | 2006-06-09 | 2009-06-24 | 惠氏公司 | 增强认知功能的方法 |
| TW200808730A (en) | 2006-06-09 | 2008-02-16 | Wyeth Corp | Process for synthesizing piperazine-piperidine compounds |
| US20080199518A1 (en) | 2006-11-28 | 2008-08-21 | Wyeth | Controlled-release formulation of piperazine-piperidine antagonists and agonists of the 5-HT1A receptor having enhanced intestinal dissolution |
-
2006
- 2006-06-08 TW TW095120358A patent/TW200800959A/zh unknown
- 2006-06-09 KR KR1020087000800A patent/KR20080021134A/ko not_active Withdrawn
- 2006-06-09 AU AU2006257874A patent/AU2006257874A1/en not_active Abandoned
- 2006-06-09 BR BRPI0613491-2A patent/BRPI0613491A2/pt not_active Application Discontinuation
- 2006-06-09 WO PCT/US2006/022719 patent/WO2006135839A2/en not_active Ceased
- 2006-06-09 EP EP06772861A patent/EP1888559A2/en not_active Withdrawn
- 2006-06-09 JP JP2008516005A patent/JP2008543782A/ja active Pending
- 2006-06-09 PE PE2006000646A patent/PE20070069A1/es not_active Application Discontinuation
- 2006-06-09 US US11/450,942 patent/US7671056B2/en not_active Expired - Fee Related
- 2006-06-09 CA CA002611711A patent/CA2611711A1/en not_active Abandoned
- 2006-06-09 CN CNA2006800292484A patent/CN101243073A/zh active Pending
- 2006-06-09 GT GT200600255A patent/GT200600255A/es unknown
- 2006-06-09 MX MX2007015678A patent/MX2007015678A/es not_active Application Discontinuation
- 2006-06-09 RU RU2007146543/04A patent/RU2007146543A/ru not_active Application Discontinuation
- 2006-06-12 AR ARP060102469A patent/AR055059A1/es unknown
-
2007
- 2007-12-05 CR CR9560A patent/CR9560A/es not_active Application Discontinuation
- 2007-12-06 IL IL187972A patent/IL187972A0/en unknown
- 2007-12-07 ZA ZA200710699A patent/ZA200710699B/xx unknown
- 2007-12-11 NO NO20076344A patent/NO20076344L/no not_active Application Discontinuation
-
2008
- 2008-01-10 EC EC2008008094A patent/ECSP088094A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101243073A (zh) | 2008-08-13 |
| RU2007146543A (ru) | 2009-07-20 |
| ZA200710699B (en) | 2009-05-27 |
| KR20080021134A (ko) | 2008-03-06 |
| MX2007015678A (es) | 2008-02-20 |
| IL187972A0 (en) | 2008-03-20 |
| JP2008543782A (ja) | 2008-12-04 |
| AR055059A1 (es) | 2007-08-01 |
| ECSP088094A (es) | 2008-02-20 |
| AU2006257874A1 (en) | 2006-12-21 |
| WO2006135839A2 (en) | 2006-12-21 |
| CR9560A (es) | 2008-02-20 |
| EP1888559A2 (en) | 2008-02-20 |
| PE20070069A1 (es) | 2007-03-15 |
| WO2006135839A3 (en) | 2007-11-22 |
| TW200800959A (en) | 2008-01-01 |
| US20070027160A1 (en) | 2007-02-01 |
| CA2611711A1 (en) | 2006-12-21 |
| BRPI0613491A2 (pt) | 2011-01-11 |
| US7671056B2 (en) | 2010-03-02 |
| GT200600255A (es) | 2007-07-19 |
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