ATE441646T1 - 5-ht4-rezeptoragonistenverbindungen - Google Patents

5-ht4-rezeptoragonistenverbindungen

Info

Publication number
ATE441646T1
ATE441646T1 AT05816105T AT05816105T ATE441646T1 AT E441646 T1 ATE441646 T1 AT E441646T1 AT 05816105 T AT05816105 T AT 05816105T AT 05816105 T AT05816105 T AT 05816105T AT E441646 T1 ATE441646 T1 AT E441646T1
Authority
AT
Austria
Prior art keywords
compounds
receptor agonist
agonist compounds
receptor
carboxamide
Prior art date
Application number
AT05816105T
Other languages
English (en)
Inventor
Seok-Ki Choi
Paul Fatheree
Adam Goldblum
Lan Jiang
Daniel Long
Daniel Marquess
S Turner
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of ATE441646T1 publication Critical patent/ATE441646T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05816105T 2004-11-05 2005-11-04 5-ht4-rezeptoragonistenverbindungen ATE441646T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62518504P 2004-11-05 2004-11-05
PCT/US2005/039761 WO2006052640A1 (en) 2004-11-05 2005-11-04 5-ht4 receptor agonist compounds

Publications (1)

Publication Number Publication Date
ATE441646T1 true ATE441646T1 (de) 2009-09-15

Family

ID=35788046

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05816105T ATE441646T1 (de) 2004-11-05 2005-11-04 5-ht4-rezeptoragonistenverbindungen

Country Status (7)

Country Link
US (2) US7399862B2 (de)
EP (1) EP1807422B1 (de)
JP (1) JP5086091B2 (de)
AT (1) ATE441646T1 (de)
DE (1) DE602005016446D1 (de)
ES (1) ES2332808T3 (de)
WO (1) WO2006052640A1 (de)

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TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
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DE602005016446D1 (de) * 2004-11-05 2009-10-15 Theravance Inc 5-HT4-Rezeptoragonistenverbindungen
KR20070091665A (ko) * 2004-12-22 2007-09-11 세라밴스 인코포레이티드 인다졸－카르복사미드 화합물
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TWI377206B (en) 2005-04-06 2012-11-21 Theravance Inc Crystalline form of a quinolinone-carboxamide compound
ES2359673T3 (es) * 2005-06-07 2011-05-25 Theravance, Inc. Compuestos de benzoimidazolona-carboxamida como agonista del receptor 5-ht4.
MY143574A (en) * 2005-11-22 2011-05-31 Theravance Inc Carbamate compounds as 5-ht4 receptor agonists
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US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
CN102639526B (zh) 2009-09-14 2014-06-04 苏文生命科学有限公司 作为5-ht4受体配体的1,2-二氢-2-氧代喹啉化合物
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MY192815A (en) * 2011-12-22 2022-09-09 Connexios Life Sciences Pvt Ltd Derivatives of aza adamantanes and uses thereof
JP2015525202A (ja) 2012-05-03 2015-09-03 ノバルティス アーゲー グレリン受容体アゴニストとしての２，７−ジアザ−スピロ［４，５］デカ−７−イル誘導体のｌ−リンゴ酸塩およびその結晶形態
IL314038A (en) 2022-01-11 2024-09-01 Suven Life Sciences Ltd Pyrrolo[1,2-b]-2-pyridazinone compounds as 5-HT4 receptor agonists

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Also Published As

Publication number Publication date
WO2006052640A1 (en) 2006-05-18
JP5086091B2 (ja) 2012-11-28
EP1807422A1 (de) 2007-07-18
US7534889B2 (en) 2009-05-19
EP1807422B1 (de) 2009-09-02
US20080255187A1 (en) 2008-10-16
US20060100236A1 (en) 2006-05-11
US7399862B2 (en) 2008-07-15
JP2008518965A (ja) 2008-06-05
ES2332808T3 (es) 2010-02-12
DE602005016446D1 (de) 2009-10-15

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