NO20081367L - Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika - Google Patents

Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Info

Publication number: NO20081367L
Authority: NO; Norway
Prior art keywords: phenyl; processes; preparation; phenyl group; pharmaceuticals
Prior art date: 2005-09-29

Application number

NO20081367A

Other languages

English (en)

Norwegian (no)

Inventor

Patrick Bernardelli

Stefanie Keil

Matthias Urmann

Hans Matter

Wolfgang Wendler

Maike Glien

Karen Chandross

Lan Lee

Corinne Terrier

Herve Minoux

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-09-29

Filing date

2008-03-14

Publication date

2008-06-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35809809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081367(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-03-14 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2008-06-13 Publication of NO20081367L publication Critical patent/NO20081367L/no

Links

125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
INVHTFJJZGBKTM-UHFFFAOYSA-N 5-phenyl-1,2,4-oxadiazol-3-one Chemical class OC1=NOC(C=2C=CC=CC=2)=N1 INVHTFJJZGBKTM-UHFFFAOYSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
229940122054 Peroxisome proliferator-activated receptor delta agonist Drugs 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
230000003210 demyelinating effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000004129 fatty acid metabolism Effects 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1
210000001428 peripheral nervous system Anatomy 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
- A—HUMAN NECESSITIES
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)

NO20081367A 2005-09-29 2008-03-14 Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika NO20081367L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP05021235		2005-09-29
PCT/EP2006/009298 WO2007039172A1 (en)	2005-09-29	2006-09-26	Phenyl- and pyridyl-i, 2 , 4 -oxadiazolone derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number	Publication Date
NO20081367L true NO20081367L (no)	2008-06-13

Family

ID=35809809

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20081367A NO20081367L (no)	2005-09-29	2008-03-14	Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika
NO20081370A NO20081370L (no)	2005-09-29	2008-03-14	Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20081370A NO20081370L (no)	2005-09-29	2008-03-14	Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Country Status (31)

Country	Link
US (3)	US20080287409A1 (de)
EP (2)	EP1931660B1 (de)
JP (2)	JP2009509986A (de)
KR (2)	KR20080048520A (de)
CN (2)	CN101273036A (de)
AR (2)	AR056203A1 (de)
AT (1)	ATE537167T1 (de)
AU (2)	AU2006299092A1 (de)
BR (2)	BRPI0616465A2 (de)
CA (2)	CA2624093A1 (de)
CR (1)	CR9784A (de)
CY (1)	CY1113376T1 (de)
DK (1)	DK1931660T3 (de)
DO (2)	DOP2006000205A (de)
EC (1)	ECSP088323A (de)
ES (1)	ES2392181T3 (de)
IL (2)	IL190227A (de)
MA (2)	MA29807B1 (de)
MY (2)	MY148982A (de)
NO (2)	NO20081367L (de)
NZ (2)	NZ566878A (de)
PE (2)	PE20070545A1 (de)
PL (1)	PL1931660T3 (de)
PT (1)	PT1931660E (de)
RU (2)	RU2008112202A (de)
SI (1)	SI1931660T1 (de)
TN (1)	TNSN08145A1 (de)
TW (2)	TWI398436B (de)
UY (2)	UY29829A1 (de)
WO (2)	WO2007039172A1 (de)
ZA (1)	ZA200801630B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1586573B1 (de) *	2004-04-01	2007-02-07	Sanofi-Aventis Deutschland GmbH	Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
BRPI0715160A2 (pt)	2006-08-08	2013-06-11	Sanofi Aventis	imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
US10954231B2 (en)	2006-10-16	2021-03-23	Bionomics Limited	Anxiolytic compounds
ES2399071T3 (es)	2006-10-16	2013-03-25	Bionomics Limited	Nuevos compuestos ansiolíticos
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de)	2007-11-13	2009-07-23	Sanofi-Aventis Deutschland Gmbh	Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
US20210130285A1 (en) *	2008-03-19	2021-05-06	Aurimmed Pharma, Inc.	Novel compounds advantageous in the treatment of central nervous system diseases and disorders
US10793515B2 (en) *	2008-03-19	2020-10-06	Aurimmed Pharma, Inc.	Compounds advantageous in the treatment of central nervous system diseases and disorders
WO2010003624A2 (en)	2008-07-09	2010-01-14	Sanofi-Aventis	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
DK2470552T3 (en)	2009-08-26	2014-02-17	Sanofi Sa	NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8916593B2 (en)	2010-05-04	2014-12-23	Pfizer Inc.	Alkoxy-substituted 2-aminopyridines as ALK inhibitors
US8933024B2 (en)	2010-06-18	2015-01-13	Sanofi	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
JP2014510065A (ja)	2011-03-02	2014-04-24	バイオノミックスリミテッド	治療薬としての新規な小分子
US8710050B2 (en)	2011-03-08	2014-04-29	Sanofi	Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683704B1 (de)	2011-03-08	2014-12-17	Sanofi	Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120054A1 (de)	2011-03-08	2012-09-13	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120056A1 (de)	2011-03-08	2012-09-13	Sanofi	Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2766349B1 (de)	2011-03-08	2016-06-01	Sanofi	Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
JP6055817B2 (ja)	2011-05-12	2016-12-27	バイオノミックスリミテッド	ナフチリジンの調製方法
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
HK1200824A1 (en) *	2012-01-18	2015-08-14	Daiichi Sankyo Company, Limited	Substituted phenylazole derivative
MX2014015265A (es)	2012-06-14	2015-08-12	Basf Se	Metodos plaguicidas que utilizan compuestos de 3-piridiltiazol sustituido y derivados para combatir plagas de animales.
US10258672B2 (en)	2014-10-09	2019-04-16	Case Western Reserve University	Compositions and methods of treating root avulsion injury
CN106616029B (zh) *	2016-12-08	2020-05-01	西南大学	一种提高虹鳟抗病能力的饲料添加剂及其制备方法
CN108976150B (zh) *	2017-06-05	2022-11-18	重庆博腾制药科技股份有限公司	一种3-乙基-4-氟苯腈的制备方法
EP3651785B1 (de) *	2017-07-11	2025-11-12	Case Western Reserve University	Zusammensetzungen und verfahren zur behandlung von myelinerkrankungen
AU2019318209B2 (en)	2018-08-10	2025-09-25	Diapin Therapeutics, Llc	Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders
WO2021092279A1 (en) *	2019-11-06	2021-05-14	Board Of Regents, The University Of Texas System	Methods for the treatment of dysmyelinating/demyelinating diseases
JP7858636B2 (ja)	2020-09-10	2026-05-14	ガシャーブラム・バイオ・インコーポレイテッド	ヘテロ環ｇｌｐ－１アゴニスト
WO2025237291A1 (zh) *	2024-05-13	2025-11-20	上海翰森生物医药科技有限公司	一种异丙基异喹啉类化合物的制备方法及其中间体

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5783593A (en)	1993-11-04	1998-07-21	Abbott Laboratories	Inhibitors of squalene synthetase and protein farnesyltransferase
US5641796A (en) *	1994-11-01	1997-06-24	Eli Lilly And Company	Oral hypoglycemic agents
JP2000511883A (ja)	1996-04-19	2000-09-12	ノボノルディスクアクティーゼルスカブ	ホスホチロシン認識ユニットを有する分子のモジュレーター
JP4345230B2 (ja) *	1998-03-10	2009-10-14	小野薬品工業株式会社	カルボン酸誘導体およびその誘導体を有効成分として含有する薬剤
CA2377246A1 (en) *	1999-06-18	2000-12-28	Ranjit C. Desai	Arylthiazolidinedione and aryloxazolidinedione derivatives
GB9914977D0 (en)	1999-06-25	1999-08-25	Glaxo Group Ltd	Chemical compounds
DE10112768A1 (de)	2001-03-16	2002-09-19	Merck Patent Gmbh	Phenylderivate 3
GB0111523D0 (en)	2001-05-11	2001-07-04	Glaxo Group Ltd	Chemical compounds
AU2002323776B2 (en) *	2001-08-10	2008-07-31	Nippon Chemiphar Co., Ltd.	Activator for peroxisome proliferator-responsive receptor Delta
JP2005529077A (ja) *	2002-02-25	2005-09-29	イーライ・リリー・アンド・カンパニー	ペルオキシソーム増殖因子活性化受容体調節物質
JPWO2004080943A1 (ja)	2003-03-11	2006-06-08	小野薬品工業株式会社	シンナミルアルコール誘導体化合物およびその化合物を有効成分として含有する薬剤
US20070054902A1 (en)	2003-12-02	2007-03-08	Shionogi & Co., Ltd.	Isoxazole derivatives as peroxisome proliferator-activated receptors agonists
EP1586573B1 (de) *	2004-04-01	2007-02-07	Sanofi-Aventis Deutschland GmbH	Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
KR20060135854A (ko) *	2004-04-01	2006-12-29	아벤티스 파마슈티칼스 인크.	Ｐｐａｒ 델타 조절물질로서의 1,3,4-옥사디아졸-2-온

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Publication number	Publication date
BRPI0616457A2 (pt)	2011-06-21
MY148982A (en)	2013-06-28
UY29829A1 (es)	2007-04-30
US20080287409A1 (en)	2008-11-20
DOP2006000205A (es)	2007-03-31
IL190227A0 (en)	2009-09-22
EP1934206B1 (de)	2011-12-14
KR101342415B1 (ko)	2013-12-17
TW200811154A (en)	2008-03-01
US20090281084A1 (en)	2009-11-12
NO20081370L (no)	2008-06-17
WO2007039172A1 (en)	2007-04-12
RU2008112201A (ru)	2009-10-10
WO2007039178A2 (en)	2007-04-12
DOP2006000204A (es)	2007-03-31
US20080262036A1 (en)	2008-10-23
IL190227A (en)	2015-05-31
AU2006299092A1 (en)	2007-04-12
EP1934206A1 (de)	2008-06-25
US7834030B2 (en)	2010-11-16
PT1931660E (pt)	2012-10-30
ZA200801630B (en)	2009-01-28
SI1931660T1 (sl)	2012-12-31
UY29830A1 (es)	2007-04-30
TNSN08145A1 (en)	2009-07-14
ECSP088323A (es)	2008-04-28
PE20070545A1 (es)	2007-06-15
ATE537167T1 (de)	2011-12-15
EP1931660B1 (de)	2012-08-01
BRPI0616465A2 (pt)	2011-06-21
CR9784A (es)	2008-05-05
CA2624093A1 (en)	2007-04-12
AU2006299086A1 (en)	2007-04-12
NZ566878A (en)	2010-07-30
PE20070768A1 (es)	2007-08-22
TWI398436B (zh)	2013-06-11
EP1931660A2 (de)	2008-06-18
KR20080048494A (ko)	2008-06-02
CN101273036A (zh)	2008-09-24
CA2624105A1 (en)	2007-04-12
WO2007039178A3 (en)	2007-09-13
RU2008112202A (ru)	2009-10-10
IL190228A0 (en)	2009-09-22
US7851493B2 (en)	2010-12-14
ES2392181T3 (es)	2012-12-05
AR056541A1 (es)	2007-10-10
JP2009509989A (ja)	2009-03-12
NZ566875A (en)	2010-06-25
MA29804B1 (fr)	2008-09-01
JP2009509986A (ja)	2009-03-12
CY1113376T1 (el)	2016-06-22
TW200728293A (en)	2007-08-01
MA29807B1 (fr)	2008-09-01
JP5183479B2 (ja)	2013-04-17
DK1931660T3 (da)	2012-11-05
PL1931660T3 (pl)	2012-12-31
KR20080048520A (ko)	2008-06-02
MY149182A (en)	2013-07-31
CN101268069A (zh)	2008-09-17
AR056203A1 (es)	2007-09-26
CA2624105C (en)	2014-02-18

Legal Events

Date	Code	Title	Description
2012-04-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
MY148982A (en)	2013-06-28	Phenyl-1,2,4-oxadiazolone derivative with phenyl group, processes for their preparation and their use as pharmaceuticals
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TN2009000242A1 (en)	2010-10-18	Sulfonyl-phenyl-2h-[1,2,4]oxodiazol-5-one derivatives, processes for their preparation and their use as pharmaceuticals
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TN2009000199A1 (en)	2010-10-18	Heteromonocyclic compound and use thereof
NO20081681L (no)	2008-04-29	N-[1,3,4]-tiadiazol-2-yl-benzensulfonamider, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytika
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TW200505830A (en)	2005-02-16	Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
NO20063860L (no)	2006-08-29	7-fenylamino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav samt deres anvendelse som legemidler
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MX2007010841A (es)	2007-11-09	8-pirrolidinobenzimidazoles biciclicos sustituidos, un metodo para su produccion y su uso como medicamentos.
TW200730516A (en)	2007-08-16	Cyclic N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals
WO2008020256A3 (en)	2008-04-10	3,4-dihydrobenzo[1,2,3]thiadiazine-1,1-dioxide derivatives, process for preparation thereof, medicaments containing said derivatives and their use