NO20081370L - Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika - Google Patents

Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Info

Publication number: NO20081370L
Authority: NO; Norway
Prior art keywords: phenyl; disorders; derivatives; processes; phenyl group
Prior art date: 2005-09-29

Application number

NO20081370A

Other languages

English (en)

Norwegian (no)

Inventor

Patrick Bernardelli

Stefanie Keil

Matthias Urmann

Hans Matter

Wolfgang Wendler

Maike Glien

Karen Chandross

Lan Lee

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-09-29

Filing date

2008-03-14

Publication date

2008-06-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35809809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081370(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-03-14 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2008-06-17 Publication of NO20081370L publication Critical patent/NO20081370L/no

Links

125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
BIGWXAGEQONZGD-UHFFFAOYSA-N 2h-oxadiazol-5-one Chemical class O=C1C=NNO1 BIGWXAGEQONZGD-UHFFFAOYSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
230000003210 demyelinating effect Effects 0.000 abstract 1
230000004129 fatty acid metabolism Effects 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1
210000001428 peripheral nervous system Anatomy 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Hematology (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Child & Adolescent Psychology (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)

NO20081370A 2005-09-29 2008-03-14 Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika NO20081370L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP05021235		2005-09-29
PCT/EP2006/009304 WO2007039178A2 (en)	2005-09-29	2006-09-26	Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number	Publication Date
NO20081370L true NO20081370L (no)	2008-06-17

Family

ID=35809809

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20081367A NO20081367L (no)	2005-09-29	2008-03-14	Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika
NO20081370A NO20081370L (no)	2005-09-29	2008-03-14	Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO20081367A NO20081367L (no)	2005-09-29	2008-03-14	Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Country Status (31)

Country	Link
US (3)	US7834030B2 (de)
EP (2)	EP1934206B1 (de)
JP (2)	JP5183479B2 (de)
KR (2)	KR20080048520A (de)
CN (2)	CN101268069A (de)
AR (2)	AR056541A1 (de)
AT (1)	ATE537167T1 (de)
AU (2)	AU2006299092A1 (de)
BR (2)	BRPI0616465A2 (de)
CA (2)	CA2624105C (de)
CR (1)	CR9784A (de)
CY (1)	CY1113376T1 (de)
DK (1)	DK1931660T3 (de)
DO (2)	DOP2006000204A (de)
EC (1)	ECSP088323A (de)
ES (1)	ES2392181T3 (de)
IL (2)	IL190228A0 (de)
MA (2)	MA29804B1 (de)
MY (2)	MY148982A (de)
NO (2)	NO20081367L (de)
NZ (2)	NZ566878A (de)
PE (2)	PE20070545A1 (de)
PL (1)	PL1931660T3 (de)
PT (1)	PT1931660E (de)
RU (2)	RU2008112201A (de)
SI (1)	SI1931660T1 (de)
TN (1)	TNSN08145A1 (de)
TW (2)	TWI398436B (de)
UY (2)	UY29830A1 (de)
WO (2)	WO2007039172A1 (de)
ZA (1)	ZA200801630B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1586573B1 (de) *	2004-04-01	2007-02-07	Sanofi-Aventis Deutschland GmbH	Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
JP2010500300A (ja)	2006-08-08	2010-01-07	サノフィ−アベンティス	アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
US10954231B2 (en)	2006-10-16	2021-03-23	Bionomics Limited	Anxiolytic compounds
JP5373613B2 (ja)	2006-10-16	2013-12-18	バイオノミクスリミテッド	新規な抗不安薬化合物
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de)	2007-11-13	2009-07-23	Sanofi-Aventis Deutschland Gmbh	Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
US10793515B2 (en) *	2008-03-19	2020-10-06	Aurimmed Pharma, Inc.	Compounds advantageous in the treatment of central nervous system diseases and disorders
US20210130285A1 (en) *	2008-03-19	2021-05-06	Aurimmed Pharma, Inc.	Novel compounds advantageous in the treatment of central nervous system diseases and disorders
WO2010003624A2 (en)	2008-07-09	2010-01-14	Sanofi-Aventis	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
MX2012001729A (es)	2009-08-26	2012-06-13	Sanofi Sa	Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2566858A2 (de)	2010-05-04	2013-03-13	Pfizer Inc.	Heterocyclische derivate als alk-hemmer
WO2011157827A1 (de)	2010-06-18	2011-12-22	Sanofi	Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
CA2828780A1 (en)	2011-03-02	2012-09-07	Bionomics Limited	Novel small-molecules as therapeutics
EP2683705B1 (de)	2011-03-08	2015-04-22	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828995B2 (en)	2011-03-08	2014-09-09	Sanofi	Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120052A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8871758B2 (en)	2011-03-08	2014-10-28	Sanofi	Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683699B1 (de)	2011-03-08	2015-06-24	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2707367B1 (de)	2011-05-12	2019-10-09	Bionomics Limited	Verfahren zur herstellung von naphthyridinen
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (de)	2011-09-27	2015-10-21	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamidderivate als kinaseinhibitoren
RU2014133738A (ru)	2012-01-18	2016-03-10	Дайити Санкио Компани, Лимитед	Замещенное производное фенилазола
WO2013186089A2 (en)	2012-06-14	2013-12-19	Basf Se	Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests
US10258672B2 (en)	2014-10-09	2019-04-16	Case Western Reserve University	Compositions and methods of treating root avulsion injury
CN106616029B (zh) *	2016-12-08	2020-05-01	西南大学	一种提高虹鳟抗病能力的饲料添加剂及其制备方法
CN108976150B (zh) *	2017-06-05	2022-11-18	重庆博腾制药科技股份有限公司	一种3-乙基-4-氟苯腈的制备方法
CN111093684A (zh) *	2017-07-11	2020-05-01	凯斯西储大学	用于治疗髓鞘病症的组合物和方法
KR102919209B1 (ko)	2018-08-10	2026-01-28	다이아핀 테라퓨틱스, 엘엘씨	트리-펩타이드 그리고 대사, 심장혈관 및 염증성 장애의 치료
WO2021092279A1 (en) *	2019-11-06	2021-05-14	Board Of Regents, The University Of Texas System	Methods for the treatment of dysmyelinating/demyelinating diseases
EP4211139A4 (de)	2020-09-10	2024-12-18	Gasherbrum Bio, Inc.	Heterocyclische glp-1-agonisten
WO2025237291A1 (zh) *	2024-05-13	2025-11-20	上海翰森生物医药科技有限公司	一种异丙基异喹啉类化合物的制备方法及其中间体

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5783593A (en)	1993-11-04	1998-07-21	Abbott Laboratories	Inhibitors of squalene synthetase and protein farnesyltransferase
US5641796A (en) *	1994-11-01	1997-06-24	Eli Lilly And Company	Oral hypoglycemic agents
WO1997040017A2 (en)	1996-04-19	1997-10-30	Novo Nordisk A/S	Modulators of molecules with phosphotyrosine recognition units
ATE451346T1 (de) *	1998-03-10	2009-12-15	Ono Pharmaceutical Co	Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten
ES2277842T3 (es) *	1999-06-18	2007-08-01	MERCK & CO., INC.	Derivados de ariltiazolidindiona y de ariloxazolidindiona.
GB9914977D0 (en) *	1999-06-25	1999-08-25	Glaxo Group Ltd	Chemical compounds
DE10112768A1 (de)	2001-03-16	2002-09-19	Merck Patent Gmbh	Phenylderivate 3
GB0111523D0 (en)	2001-05-11	2001-07-04	Glaxo Group Ltd	Chemical compounds
AU2002323776B2 (en) *	2001-08-10	2008-07-31	Nippon Chemiphar Co., Ltd.	Activator for peroxisome proliferator-responsive receptor Delta
ES2290439T3 (es) *	2002-02-25	2008-02-16	Eli Lilly And Company	Moduladores del receptor activado del proliferador de peroxisomas.
JPWO2004080943A1 (ja)	2003-03-11	2006-06-08	小野薬品工業株式会社	シンナミルアルコール誘導体化合物およびその化合物を有効成分として含有する薬剤
EP1690538A4 (de)	2003-12-02	2009-02-25	Shionogi & Co	Isoxazol-derivat mit agonistischer wirkung gegen peroxisom-proliferator-aktivierten rezeptor
EP1586573B1 (de) *	2004-04-01	2007-02-07	Sanofi-Aventis Deutschland GmbH	Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
NZ550857A (en) *	2004-04-01	2009-12-24	Aventis Pharma Inc	1,3,4-oxadiazol-2-ones as PPAR delta modulators

2006
- 2006-09-26 AU AU2006299092A patent/AU2006299092A1/en not_active Abandoned
- 2006-09-26 CN CNA2006800344489A patent/CN101268069A/zh active Pending
- 2006-09-26 EP EP06805857A patent/EP1934206B1/de active Active
- 2006-09-26 CA CA2624105A patent/CA2624105C/en not_active Expired - Fee Related
- 2006-09-26 NZ NZ566878A patent/NZ566878A/en not_active IP Right Cessation
- 2006-09-26 JP JP2008532648A patent/JP5183479B2/ja not_active Expired - Fee Related
- 2006-09-26 DK DK06792252.6T patent/DK1931660T3/da active
- 2006-09-26 CA CA002624093A patent/CA2624093A1/en not_active Abandoned
- 2006-09-26 PL PL06792252T patent/PL1931660T3/pl unknown
- 2006-09-26 NZ NZ566875A patent/NZ566875A/en not_active IP Right Cessation
- 2006-09-26 KR KR1020087007735A patent/KR20080048520A/ko not_active Withdrawn
- 2006-09-26 SI SI200631453T patent/SI1931660T1/sl unknown
- 2006-09-26 WO PCT/EP2006/009298 patent/WO2007039172A1/en not_active Ceased
- 2006-09-26 RU RU2008112201/04A patent/RU2008112201A/ru not_active Application Discontinuation
- 2006-09-26 PT PT06792252T patent/PT1931660E/pt unknown
- 2006-09-26 AT AT06805857T patent/ATE537167T1/de active
- 2006-09-26 WO PCT/EP2006/009304 patent/WO2007039178A2/en not_active Ceased
- 2006-09-26 ES ES06792252T patent/ES2392181T3/es active Active
- 2006-09-26 JP JP2008532645A patent/JP2009509986A/ja not_active Abandoned
- 2006-09-26 RU RU2008112202/04A patent/RU2008112202A/ru not_active Application Discontinuation
- 2006-09-26 BR BRPI0616465-0A patent/BRPI0616465A2/pt not_active Application Discontinuation
- 2006-09-26 BR BRPI0616457-9A patent/BRPI0616457A2/pt not_active IP Right Cessation
- 2006-09-26 EP EP06792252A patent/EP1931660B1/de active Active
- 2006-09-26 CN CNA2006800359450A patent/CN101273036A/zh active Pending
- 2006-09-26 AU AU2006299086A patent/AU2006299086A1/en not_active Abandoned
- 2006-09-27 MY MYPI20064224A patent/MY148982A/en unknown
- 2006-09-27 DO DO2006000204A patent/DOP2006000204A/es unknown
- 2006-09-27 TW TW095135660A patent/TWI398436B/zh not_active IP Right Cessation
- 2006-09-27 MY MYPI20064223A patent/MY149182A/en unknown
- 2006-09-27 AR ARP060104222A patent/AR056541A1/es not_active Application Discontinuation
- 2006-09-27 TW TW095135657A patent/TW200811154A/zh unknown
- 2006-09-27 AR ARP060104225A patent/AR056203A1/es not_active Application Discontinuation
- 2006-09-27 DO DO2006000205A patent/DOP2006000205A/es unknown
- 2006-09-28 PE PE2006001178A patent/PE20070545A1/es not_active Application Discontinuation
- 2006-09-29 UY UY29830A patent/UY29830A1/es not_active Application Discontinuation
- 2006-09-29 UY UY29829A patent/UY29829A1/es not_active Application Discontinuation
- 2006-09-29 PE PE2006001189A patent/PE20070768A1/es not_active Application Discontinuation
2008
- 2008-02-19 ZA ZA2008/01630A patent/ZA200801630B/en unknown
- 2008-02-29 CR CR9784A patent/CR9784A/es not_active Application Discontinuation
- 2008-03-14 NO NO20081367A patent/NO20081367L/no not_active Application Discontinuation
- 2008-03-14 NO NO20081370A patent/NO20081370L/no not_active Application Discontinuation
- 2008-03-17 IL IL190228A patent/IL190228A0/en unknown
- 2008-03-17 IL IL190227A patent/IL190227A/en not_active IP Right Cessation
- 2008-03-24 MA MA30780A patent/MA29804B1/fr unknown
- 2008-03-24 MA MA30783A patent/MA29807B1/fr unknown
- 2008-03-25 KR KR1020087007148A patent/KR101342415B1/ko not_active Expired - Fee Related
- 2008-03-26 US US12/055,764 patent/US7834030B2/en not_active Expired - Fee Related
- 2008-03-26 US US12/055,793 patent/US20080287409A1/en not_active Abandoned
- 2008-03-27 EC EC2008008323A patent/ECSP088323A/es unknown
- 2008-03-28 TN TNP2008000145A patent/TNSN08145A1/en unknown
2009
- 2009-05-29 US US12/474,838 patent/US7851493B2/en not_active Expired - Fee Related
2012
- 2012-10-31 CY CY20121101040T patent/CY1113376T1/el unknown

Also Published As

Publication number	Publication date
AR056541A1 (es)	2007-10-10
US20090281084A1 (en)	2009-11-12
MA29804B1 (fr)	2008-09-01
BRPI0616457A2 (pt)	2011-06-21
EP1934206A1 (de)	2008-06-25
TNSN08145A1 (en)	2009-07-14
UY29830A1 (es)	2007-04-30
JP2009509989A (ja)	2009-03-12
WO2007039178A3 (en)	2007-09-13
CN101273036A (zh)	2008-09-24
NZ566875A (en)	2010-06-25
ECSP088323A (es)	2008-04-28
DOP2006000204A (es)	2007-03-31
SI1931660T1 (sl)	2012-12-31
ES2392181T3 (es)	2012-12-05
KR20080048494A (ko)	2008-06-02
US7851493B2 (en)	2010-12-14
TW200811154A (en)	2008-03-01
MY149182A (en)	2013-07-31
UY29829A1 (es)	2007-04-30
RU2008112201A (ru)	2009-10-10
CA2624105A1 (en)	2007-04-12
KR20080048520A (ko)	2008-06-02
PE20070768A1 (es)	2007-08-22
DK1931660T3 (da)	2012-11-05
BRPI0616465A2 (pt)	2011-06-21
NZ566878A (en)	2010-07-30
PE20070545A1 (es)	2007-06-15
ZA200801630B (en)	2009-01-28
WO2007039172A1 (en)	2007-04-12
EP1931660B1 (de)	2012-08-01
IL190228A0 (en)	2009-09-22
KR101342415B1 (ko)	2013-12-17
CA2624105C (en)	2014-02-18
AU2006299092A1 (en)	2007-04-12
DOP2006000205A (es)	2007-03-31
US20080262036A1 (en)	2008-10-23
WO2007039178A2 (en)	2007-04-12
CR9784A (es)	2008-05-05
JP5183479B2 (ja)	2013-04-17
ATE537167T1 (de)	2011-12-15
NO20081367L (no)	2008-06-13
MA29807B1 (fr)	2008-09-01
MY148982A (en)	2013-06-28
PL1931660T3 (pl)	2012-12-31
AU2006299086A1 (en)	2007-04-12
JP2009509986A (ja)	2009-03-12
CY1113376T1 (el)	2016-06-22
TW200728293A (en)	2007-08-01
TWI398436B (zh)	2013-06-11
IL190227A0 (en)	2009-09-22
CN101268069A (zh)	2008-09-17
EP1934206B1 (de)	2011-12-14
US20080287409A1 (en)	2008-11-20
IL190227A (en)	2015-05-31
US7834030B2 (en)	2010-11-16
AR056203A1 (es)	2007-09-26
PT1931660E (pt)	2012-10-30
RU2008112202A (ru)	2009-10-10
CA2624093A1 (en)	2007-04-12
EP1931660A2 (de)	2008-06-18

Legal Events

Date	Code	Title	Description
2018-04-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20081370L (no)	2008-06-17	Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika
NO20081369L (no)	2008-05-28	Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika
NO20092293L (no)	2009-09-08	Sulfonyl-fenyl-2H-[1,2,4]oksodiazol-5-onderivater, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytiske midler
NO20064201L (no)	2006-12-13	Glukopyranosylsubstituerte benzolderivater, medikamenter inneholdende slike forbindelser, deres anvendelse og fremstilling
NO20073719L (no)	2007-08-22	Kjemiske forbindelser
NO20081682L (no)	2008-05-06	4-oksy-N-[1,3,4]-tiadiazol-2-yl-benzensulfonamider, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika
WO2008062905A3 (en)	2008-12-04	Heteromonocyclic compound and use thereof
WO2008055870A8 (en)	2008-12-24	Glucopyranosyl-substituted benzyl-benzonitrile derivatives, medicaments containing such compounds, their use and process for their manufacture
WO2008034859A8 (en)	2008-06-12	Glucopyranosyl-substituted difluorobenzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
NO20075641L (no)	2007-11-20	Kroman og kromenderivater og ders anvendelse
NO20084845L (no)	2009-02-03	2-pyrazinonderivater for behandling av sykdom eller tilstander der inhibiering av neutrofil elastaseaktivitetet er gunstig
TW200505880A (en)	2005-02-16	Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals
NO20056010L (no)	2006-01-20	Biaryloksymetylaren-karboksylsyrer
NO20081681L (no)	2008-04-29	N-[1,3,4]-tiadiazol-2-yl-benzensulfonamider, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytika
TW200510352A (en)	2005-03-16	Cycloalkyl substituted amino acid derivatives, processes for their freparation and their use as pharmaceuticals
TW200616985A (en)	2006-06-01	Salicylthiazoles substituted by diphenylamine or diphenylamine derivatives, process for their preparation and their use
TNSN06317A1 (en)	2007-12-03	Oxadiazolone derivatives as ppar delta agonists
NO20084177L (no)	2008-11-12	Substituerte Imidazo[2,1-B]thiazolforbindelser og deres anvendelse for produksjon av legemidler
NO20064951L (no)	2006-10-30	1,3,4-oksadiazol-2-oner som PPAR delta-modulatorer og deres anvendelse
TW200621732A (en)	2006-07-01	Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
NO20081676L (no)	2008-04-29	Bicykliske aryl-sulfonylsyre[1,3,4]-tiadlazol-2-yl-amlder, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytika
NO20081675L (no)	2008-04-23	Cykliske N-[1,3,4]-tiadiazol-2-yl-benzensulfonamlder, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytika
NO20081368L (no)	2008-06-18	Derivater av 2-amintiazoler og 2-aminooksazoler, fremgangsmate for fremstilling derav samt deres anvendelse som farmasoytika
TW200510399A (en)	2005-03-16	1, 3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups; processes for their preparation and their use as pharmaceuticals
IL176914A0 (en)	2006-12-10	Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments